1. Plasmon resonance gold nanoparticles for improving optical diagnostics and photothermal therapy of tumor

    Plasmon resonance gold nanoparticles for improving optical diagnostics and photothermal therapy of tumor
    The study was performed on 16 CBA-line female mice with transplanted cervical cancer. 0.2 ml of gold nanoparticle solution with a concentration of 109 particles/ml were injected into the animals intravenously. The particles were 200-250 nm in size; the plasmon-resonance related extinction maximum was at the wavelength of 850-950 nm. Accumulation of the nanoparticles into tumor node was visualized by the method of optical coherence tomography (OCT). When the accumulation of nanoparticles in the tumor was maximal, hyperthermia was accomplished using the LSP-AZOR laser setup generating cw radiation at 810 nm. The duration of exposition was 20 min ...
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