Diagnostic Efficacy of Real-Time Optical Coherence Tomography in the Management of Preinvasive and Invasive Neoplasia of the Uterine Cervix

Entities Mentioned

• Imalux
• Nancy J. Tresser

1. Objective: Determine the sensitivity and specificity of optical coherence tomography (OCT) as an adjunct to colposcopy in the detection of cervical intraepithelial neoplasia (CIN) grade 2 or higher in a real-time clinical evaluation. Background: Optical coherence tomography (OCT) uses infrared light similar to ultrasound pulse-echo imaging. Image resolution is optimal in the 1-to-3-mm range. This study is the third in our series of OCT investigations and our first real-time clinical trial. The study was conducted at the Peking University Shenzhen Hospital, Shenzhen, China. Methods: Nonpregnant women 18 years or older with abnormal cervical cytologic findings or a positive high-risk human ... (Read Full Article)

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