1. Prior Aspirin Therapy Associated with Less Thrombus in Stemi Patients

    Prior Aspirin Therapy Associated with Less Thrombus in Stemi Patients
    A small study linking previous aspirin therapy with lower thrombus burden in patients undergoing primary percutaneous coronary intervention (PCI) shows the potential mechanism by which the antiplatelet drug may prevent or lessen the damage of an ST-segment elevation myocardial infarction (STEMI), according to findings published online January 25, 2010, ahead of print in the American Journal of Cardiology. Researchers led by Giampaolo Niccoli, MD, PhD, of Catholic University of the Sacred Heart (Rome, Italy), looked at the relationship between previous aspirin therapy and angiographic thrombus grade in 91 consecutive patients at their institution undergoing primary PCI for a first STEMI ...
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    1. The fundamental difficulty is that angiography is a bad way to look at thrombus...In the absence of a total occlusion, where you can’t estimate thrombus, the only technique that might have a chance to provide a good estimate is optical coherence tomography (OCT), because OCT can distinguish between plaque and thrombus while IVUS cannot.
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