Optical Coherence Tomography-Measured Pigment Epithelial Detachment Height As A Predictor for Retinal Pigment Epithelial Tears Associated With Intravitreal Bevacizumab Injections

Entities Mentioned

• Zeiss Stratus OCT
• Cleveland Clinic
• Peter K. Kaiser

1. Purpose: The purpose was to study preinjection optical coherence tomography-related factors in age-related macular degeneration eyes with retinal pigment epithelial detachment (PED) that may predispose retinal pigment epithelial (RPE) tears associated with intravitreal bevacizumab injections. Methods: This multicenter retrospective case series involving 9 retina specialists and 7 centers investigated Stratus optical coherence tomography parameters in eyes with vascularized PED (vPED) from February 2006 to February 2007. Of the 1,280 eyes in 1,255 patients receiving 2,890 intravitreal injections, there were 125 eyes with vPED. For every vPED eye that developed an RPE tear (Group 1), 3 or more vPED eyes ... (Read Full Article)

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