1. Ultra-high Resolution Measurement by Optical Coherence Tomography of Dynamic Tear Film Changes on Contact Lenses

    Purpose: To determine the dynamic pre- (PLTF) and post-lens (PoLTF) tear film thicknesses using optical coherence tomography (OCT). Methods: Ultra-high resolution OCT was used to image the tear film of 22 subjects before and after contact lens wear. A soft lens with one drop of artificial tears on its concave surface was inserted onto one randomly selected eye. OCT images were taken before insertion, immediately afterwards, and every 2 minutes for 10 minutes. For the contralateral eye, the lens inserted was not pre-wetted on the concave surface. OCT images were taken before insertion, immediately afterwards, and at 3 minutes. Then ...
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