Feature Of The Week 11/15/09: A Comparison between Optical Coherence Tomography and Histology of Laryngeal Epithelial Thickness
Feature Of The Week 11/15/09: While applications of optical coherence tomography in ophthalmology and cardiology have very successfully transitioned from the research world to the commercial world many other fields have lagged behind. One such area is the field of Otolaryngology. While much of the technology developed in both the academic and commercial worlds is directly applicable to applications in otolaryngology there remain some unique features such as probe design and a need for additional clinical data to determine where OCT will be most beneficial. Numerous researchers around the world are working in this field. Researchers from the University of California at Irvine have been very active in this field and in a recent study analyzed the epithelial thickness of the different laryngeal subsites in-vivo using OCT and compared this images with conventional histology. It is critically important to know the normal thickness of these layers, since they thickened in pathological conditions. The study concludes: "Optical coherence tomography does not have the artifacts associated with conventional histologic techniques. The inevitable development of office-based optical coherence tomography devices will increase the precision of laryngeal measurements and contribute to the clinical application of this technology in diagnosing laryngeal disease." For more information see recent Article or click on Otolaryngology. Courtesy Dr. Marc Rubinstein. Click "Full Screen" for better viewing.