1. Detection of Vulnerable Plaque by Multislice Computed Tomography, Comparative Study With Optical Coherence Tomography

    Background: Acute coronary syndrome is commonly caused by disruption of vulnerable plaque that is characterized by thin fibrous cap (<65 ┬Ám) and large lipid pool. Noninvasive detection of vulnerable plaque using multislice computed tomography (MSCT) could be useful for risk stratification in patients with coronary artery disease. The purpose of this study is to investigate the possibility of MSCT to detect a thin-capped fibroatheroma (TCFA) by comparing the optical coherence tomography (OCT) findings. Methods and results: From January 2008 to March 2009, 77 lesions (19 unstable angina pectoris (uAP) culprit, 19 uAP non-culprit and 39 stable angina pectoris) in 43 ...
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