1. Surgical diagnostics, guidance, and intervention using optical coherence tomography (Thesis)

    Surgical diagnostics, guidance, and intervention using optical coherence tomography (Thesis)
    Advances in biomedical imaging technology are rapidly becoming integrated into the surgical suite for image-guidance of interventional procedures. Clinical imaging modalities including computed tomography, magnetic resonance imagine, and ultrasound offer resolutions sufficient to guide placement of surgical instruments, but insufficient to resolve tissue and cellular microstructure. Optical coherence tomography (OCT) is a new high-resolution biomedical imaging modality based on the detection of backscattered near-infrared laser light from tissue. The compact fiber-optical based OCT technology is capable of micron-scale resolution real-time imaging in non-transparent highly-scattering tissue.
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