Optical coherence tomography imaging of psoriasis vulgaris: correlation with histology and disease severity

Entities Mentioned

• University of Copenhagen
• Lars Thrane
• Technical University of Denmark
• Gregor B. E. Jemec

1. Epidermal thickness (ET) has been suggested as a surrogate measure of psoriasis severity. Optical coherence tomography (OCT) is a recent imaging technology that provides real-time skin images to a depth of 1.8 mm with a micrometre resolution. OCT may provide an accurate in vivo measure of ET. It is, therefore, speculated that OCT may be used in the assessment of psoriasis vulgaris. A total of 23 patients with psoriasis vulgaris were systematically evaluated by OCT imaging and skin biopsy during treatment. Biopsies were graded for disease severity, and additional evaluation was done by the physician via psoriasis area and severity ... (Read Full Article)

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