1. Effects on Choroidal Neovascularizations after Anti-VEGF Upload Using Intravitreal Ranibizumab as Determined by Spectral Domain Optical Coherence Tomography

    Purpose: To image CNV structure before and after anti-VEGF treatment using spectral domain optical coherence tomography (SD-OCT). Material and methods: In 78 patients newly diagnosed CNVs (classic CNV: n=16; occult CNV: n=54; minimal classic CNV: n=8) due to AMD were imaged before and 4 weeks after anti-VEGF upload with 3 intravitreal injections of Ranibizumab. Qualitative (structural changes) and quantitative measurements (diameter and thickness) of the CNVs were obtained from the OCT images using the Heidelberg Eye Explorer software. Results: Classic CNV components were observed above the RPE/photoreceptor complex, whereas occult CNVs stayed below. Qualitatively, overall CNV ...
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