Optical Coherence Tomography Imaging in Developmental Biology
Optical coherence tomography (OCT) is an attractive imaging technique for developmental biology because it permits the imaging
of tissue microstructure in situ, yielding micron-scale image resolution without the need for excision of a specimen and tissue processing. OCT enables repeated
imaging studies to be performed on the same specimen in order to track developmental changes. OCT is analogous to ultrasound
B mode imaging except that it uses low-coherence light rather than sound and performs cross-sectional imaging by measuring
the backscattered intensity of light from structures in tissue (1). The principles of OCT imaging are shown schematically in Fig. 1. The ...
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