1. Relationship between Retinal Structures and Retinal Vessel Caliber in Normal Adolescents

    Aims: To describe the normal physiological relationships between retinal arteriolar and venular caliber with retinal nerve fiber layer (RNFL), macular and optic nerve head parameters. Methods: The Sydney Childhood Eye Study assessed 2038 adolescents aged 12 years. Retinal vessel calibers were measured from digital fundus photographs using standardized protocols. Optical coherence tomography (StratusOCT) measurements of RNFL, macular and optic nerve head parameters were obtained using the 'fast' scan protocol. Mixed model analyses were performed. Results: After adjusting for covariates, each µm increase in RNFL thickness was associated with a 0.22µm (0.15%, p<0.0001) and 0.49µm (0 ...
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