1. New and Current Clinical Imaging Techniques To Study Chronic Obstructive Pulmonary Disease

    Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease, characterized by both small airway and parenchymal abnormalities. There is increasing evidence to suggest that these two morphologic phenotypes, while related, may have different clinical presentations, prognosis and therapeutic responses to medications. With the advent of novel imaging modalities, it is now possible to evaluate these two morphologic phenotypes in large clinical studies using non or minially invasive methods such as computed tomography (CT), magentic resonance imaging (MRI) and optical coherence tomography (OCT). In this paper, we provide a pictorial overview of these modalities in the context of COPD and discuss ...

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