1. Spectral Domain Optical Coherence Tomography Characteristics of Cuticular Drusen

    Purpose: To evaluate the appearance of cuticular drusen with spectral domain optical coherence tomography. Methods: Eyes of patients with cuticular drusen were imaged using a prototype spectral domain optical coherence tomography instrument with 5-μm axial resolution. Thickness maps were obtained after automated segmentation of the internal limiting membrane and retinal pigment epithelium layers using a proprietary algorithm. The volume of subretinal fluid (SRF) was calculated using a manual segmentation technique that involved drawing boundaries around the SRF. The repeatability of these measurements was tested by comparing the volume measurements from multiple scans performed on the same day in four eyes ...
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