1. Rotational Atherectomy or Balloon-Based Techniques to Prepare Severely Calcified Coronary Lesions

    Rotational Atherectomy or Balloon-Based Techniques to Prepare Severely Calcified Coronary Lesions

    Background The comparative efficacy of percutaneous techniques for the preparation of calcified lesions before stenting remains poorly studied. Objectives This study sought to compare the performance of up-front rotational atherectomy (RA) or balloon-based techniques before drug-eluting stent implantation in severely calcified coronary lesions as assessed by angiography and optical coherence tomography (OCT). Methods Patient-level data from the PREPARE-CALC (Comparison of Strategies to Prepare Severely Calcified Coronary Lesions) and ISAR-CALC (Comparison of Strategies to Prepare Severely Calcified Coronary Lesions) randomized trials were pooled. The primary endpoint was stent expansion as assessed by OCT imaging. The secondary endpoints included stent eccentricity, stent ...

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