Reproducibility of quantitative optical coherence tomography for stent analysis

Entities Mentioned

• Patrick W. Serruys
• Case Western Reserve University
• Evelyn Regar
• Marco A. Costa
• Hector M. Garcia-Garcia
• Nieves Gonzalo
• Hiram G. Bezerra
• LightLab Imaging
• Thoraxcenter at Erasmus University Medical Center

1. Aims: To assess the inter- and intra- observer reproducibility for strut count, strut apposition and strut tissue coverage measurements with optical coherence tomography (OCT).Methods and results: Ten drug-eluting stents (244 frames, 1712 struts) imaged with OCT nine months after implantation were analysed by two independent analysts. One of the analysts repeated the analysis of five stents (120 frames, 795 struts) one week later. Offline analysis was performed with the proprietary LightLab Imaging software. The number of struts was counted and lumen and stent area contours were traced. Tissue coverage thickness was measured at 360 degrees of vessel circumference and ... (Read Full Article)

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