1. Line-Field Confocal Optical Coherence Tomography of Lentigo Maligna with Horizontal and Vertical Histopathologic Correlations

    Line-Field Confocal Optical Coherence Tomography of Lentigo Maligna with Horizontal and Vertical Histopathologic Correlations

    Lentigo maligna (LM) is a subtype of in situ melanoma that classically presents in elderly patients as a slowly growing lesion on sun-exposed areas that may evolve to invasive melanoma (LMM). Line-field confocal optical coherence tomography (LC-OCT) is a new non-invasive technique for a real-time, vertical and horizontal skin imaging with high resolution close to conventional histopathology. We present the LC-OCT features of a LM of the nose in 49-year-old white man along with their horizontal and vertical histopathological correlations. LC-OCT was able to detect in vivo, in both horizontal and vertical imaging, the main microscopic features typical of LM ...

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