1. Development of a non-uniform discrete Fourier transform based high speed spectral domain optical coherence tomography system We develop a high speed spectral domain optical coherence tomography (SD-OCT) system based on a custom-built spectrometer and non-uniform discrete Fourier transform (NDFT) to realize minimized depth dependent sensitivity fall-off. After precise spectral calibration of the spectrometer, NDFT of the acquired spectral data is adopted for image reconstruction. The spectrometer is able to measure a wavelength range of about 138nm with a spectral resolution of 0.0674nm at central wavelength of 835nm, corresponding to an axial imaging range of 2.56mm in air. Zemax simulations and sensitivity fall-off measurements under two alignment states of the spectrometer are given. Both theoretical simulations and ... (Read Full Article)

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