1. A study of macular hole formation by serial spectral optical coherence tomography

    Background: The purpose of this paper is to evaluate changes of the vitreoretinal interface in fellow eyes of eyes with a macular hole and to study early stages of macular hole formation by spectral optical coherence tomography (SOCT).Methods: A prospective study of 131 consecutive patients with history of macular hole. Serial SOCT examinations were performed on the fellow eyes four times during a 6-month observation period. Progression of foveal changes and formation of macular hole in the fellow eyes were studied.Results: Seven distinct abnormalities in the foveal region were noted in 70 of the fellow eyes (53.4 ...
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