1. Widefield OCT Imaging for Quantifying Inner Retinal Thickness in the Nonhuman Primate

    Widefield OCT Imaging for Quantifying Inner Retinal Thickness in the Nonhuman Primate

    Purpose: To determine the agreement and repeatability of inner retinal thickness measures from widefield imaging compared to standard scans in healthy nonhuman primates. Methods: Optical coherence tomography (OCT) scans were acquired from 30 healthy rhesus monkeys, with 11 animals scanned at multiple visits. The scan protocol included 20° × 20° raster scans centered on the macula and optic nerve head (ONH), a 12° diameter circular scan centered on the ONH, and a 55 × 45° widefield raster scan. Each scan was segmented using custom neural network-based algorithms. Bland-Altman analysis were used for comparing average circumpapillary retinal nerve fiber layer (RNFL) thickness and ...

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