1. Structural-visual functional relationships detected by optical coherence tomography in varying age-cohorts' patients with optic neuritis

    Structural-visual functional relationships detected by optical coherence tomography in varying age-cohorts' patients with optic neuritis

    Aim: To assess the relationships of final best-corrected visual acuity (BCVA) and the optic nerve structural loss in varying age-cohorts of optic neuritis (ON) patients. Methods: This is a retrospective, cross-sectional study. Totally 130 ON subjects (200 eyes) without ON onset within 6mo were included, who underwent BCVA assessment, peripapillary retinal nerve fibre layer (pRNFL) and macular segmented layers evaluation by optical coherence tomography (OCT). Results: For the 0-18y cohort, the final BCVA (logMAR) was significantly better and less frequent recurrences than adult cohorts ( P =0.000). The final BCVA (logMAR) in all age-cohorts of the ON patients had negative ...

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