1. Measuring airway dimensions during bronchoscopy using anatomical optical coherence tomography

    Airway dimensions are difficult to quantify bronchoscopically because of optical distortion and a limited ability to gauge depth. Anatomical optical coherence tomography (aOCT), a novel imaging technique, may overcome these limitations. This study evaluated the accuracy of aOCT against existing techniques in phantom, excised pig and in vivo human airways. Three comparative studies were performed: (i) micrometer-derived area measurements in ten plastic tubes were compared to aOCT-derived area; (ii) aOCT-derived airway compliance curves from excised pig airways were compared to curves derived using an endoscopic technique; and (iii) airway dimensions from the trachea to subsegmental bronchi were measured using aOCT ...

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