1. Applications of Visible-Light Optical Coherence Tomography in the Eye and Brain -

    Applications of Visible-Light Optical Coherence Tomography in the Eye and Brain -

    Optical coherence tomography (OCT) is a non-invasive, label-free technology that can image biological tissues in vivo with micrometer-scale resolution. Since its development in 1991, OCT has been successfully commercialized and widely adopted in the clinic for the diagnosis and monitoring of retinal diseases. A typical commercial OCT system may have an axial resolution of 5-10 micrometers. By shortening the wavelength range of the light source, visible-light OCT (vis-OCT) enables an improved axial resolution of 1-micrometer, improved tissue scattering contrasts, and additional functional information. The bulk of this dissertation focuses on vis-OCT imaging of the Schlemm’s canal and limbal vascular ...

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