1. Using the Dynamic Forward Scattering Signal for Optical Coherence Tomography based Blood Flow Quantification

    Using the Dynamic Forward Scattering Signal for Optical Coherence Tomography based Blood Flow Quantification

    To our knowledge, all existing optical coherence tomography approaches for quantifying blood flow, whether Doppler-based or decorrelation-based, analyze the light that is back-scattered by moving red blood cells (RBCs). This work investigates the potential advantages of basing these measurements of the light that is forward-scattered by RBCs, i.e., by looking at the signals back-scattered from below the vessel. We show experimentally that this results in a flowmetry measure that is insensitive to vessel orientation for vessels that are approximately orthogonal to the imaging beam. We further provide proof-of-principle demonstrations that DFS can be used to measure flow in human ...

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