1. Changes in Central Corneal Thickness of Preserved Corneas Over Time Measured Using Anterior Segment Optical Coherence Tomography

    Purpose: To measure central corneal thickness (CCT) and investigate serial changes in CCT, using anterior segment optical coherence tomography (AS-OCT) on corneas in storage medium. Methods: Between July and August 2006, 10 human corneoscleral discs from 5 donors between 19 and 57 years of age were obtained. Corneoscleral rims were excised and were transferred to Optisol-GS (Bausch & Lomb, Irvine, CA). After preservation, AS-OCT (Visante OCT; Carl Zeiss Meditec) was performed on all corneoscleral discs to detect serial changes in CCT. The corneas were measured with AS-OCT at 0.5, 1, 2, 3, 4, 6, and 12 hours and then at 1, 2, 3, and 4 days after preservation ...
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