1. Diagnosis of macular pseudoholes and lamellar macular holes: is optical coherence tomography the gold standard?

    Aims: To assess fundus autofluorescence (AF) for better differential diagnosis of macular pseudoholes (MPH) and lamellar macular holes (LMH) evaluated with optical coherence tomography (OCT) as the gold standard. Methods: We reviewed the files of 50 eyes of 46 consecutive patients who were diagnosed by OCT as having a foveal defect with residual retinal tissue at the bottom. Retinal thickness was measured at the foveal center and 750 µm temporally and nasally to differentiate further MPH and LMH. The corresponding corrected AF images were then evaluated. Eyes with either macular pucker or stage 1a impending macular hole served as controls ...
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