1. Evaluating Onychomycosis Outcomes 2 Months into an 11-month-long Efinaconazole Regimen: The Role of Optical Coherence Tomography

    Evaluating Onychomycosis Outcomes 2 Months into an 11-month-long Efinaconazole Regimen: The Role of Optical Coherence Tomography

    Background. Onychomycosis affects 43 million people in the United States and Europe. Topical therapies can be effective but require lengthy and costly regimens without an established method for predicting the treatment outcome. Objective. We studied the role of optical coherence tomography (OCT), a noninvasive imaging device approved by the United States Food and Drug Administration, in evaluating onychomycosis treatment outcomes. Methods. This investigator-initiated prospective clinical study recruited subjects from two urban medical centers. A total of 34 subjects with mild-to-moderate onychomycosis, confirmed using periodic acid-Schiff (PAS) staining, were treated with topical efinaconazole for 48 weeks, at which time a final ...

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