New York University School of Medicine Receives NIH Grant for True Sub-Micron Ocular Diagnostics with Visible Light Optical Coherence Tomography
New York University School of Medicine Receives a 2021 NIH Grant for $468,446 for True Sub-Micron Ocular Diagnostics with Visible Light Optical Coherence Tomography. The principal investigator is Vivek Srinivasan. Below is a summary of the proposed work.
The earliest changes in the photoreceptors, retinal pigment epithelium, and Bruch’s membrane in age-related macular degeneration (AMD) are subtle and challenging to detect non-invasively. Here, we will develop and validate a new in vivo imaging technology, visible light Optical Coherence Tomography (OCT), which, if implemented carefully, delineates these layers with unprecedented depth resolution and functional contrast. The ability to precisely characterize and quantify these early changes will lead to a better understanding of aging in the retina and prediction of progression to end-stage disease and blindness, which will aid in assessing potential treatments.