Evaluation of the Cirrus HD-OCT Normative Database Probability Codes in an African American Population

Objective: Race-adjusted interpretation of data from Cirrus high-definition optical coherence tomography (HD-OCT) devices is not standard practice. The aim of this study is to evaluate differences in peripapillary retinal nerve fiber layer (RNFL) thickness between healthy African Americans and the Cirrus HD-OCT normative database. Design: This is a cross-sectional observational study using control patients recruited from the greater Philadelphia, Pennsylvania area. Subjects: A total of 466 eyes were included in this study. Subjects were retrospectively identified from the control cohort of the Primary Open-Angle African American Glaucoma Genetics (POAAGG) study. Methods: Using an age-stratified or linear regression method, we reclassified ...
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