Impact of cardiometabolic factors on retinal vasculature: A 3x3, 6x6 and 8x8-mm optical coherence tomography angiography study

Background: Optical coherence tomography angiography (OCTA) is available in varying size and resolution. We sought to characterize associations of cardiometabolic factors with retinal microvascular changes using 3x3-mm, 6x6-mm and 8x8-mm OCTA scans to determine differences in detection with varying scan size. Methods: Cross-sectional study of 247 cardiovascular patients from a single-centre tertiary-care hospital. Demographic, comorbidity, and medication data were obtained. Patients underwent 3x3-mm, 6x6-mm and 8x8-mm macula OCTA scanning using Carl Zeiss CIRRUS HD-OCT Model 5000. Angioplex and AngioTool software was used to quantify vascular parameters in the superficial capillary plexus. Results: Increasing age, hypertension, dyslipidemia, diabetes, chronic kidney disease ...
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