1. Clinical significance of neoatherosclerosis observed at very late phase between 3 and 7 years after coronary stent implantation

    Clinical significance of neoatherosclerosis observed at very late phase between 3 and 7 years after coronary stent implantation

    Background Clinical significance of neoatherosclerosis (NA) observed at very late phase remains undetermined. We sought to investigate the association between NA observed by optical coherence tomography (OCT) 3–7 years after stenting and subsequent clinical outcomes. Methods We investigated previously implanted stents without stent failure in the institutional OCT database at Tsuchiura Kyodo General Hospital. Qualitative and quantitative OCT analyses were performed. In patient-based analysis, major adverse cardiac events (MACE) included all-cause death, non-fatal myocardial infarction, and clinically driven revascularization. MACE-free survival rate was compared between patients with any stent showing NA (NA group) and those without NA (non-NA group ...

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