1. Quantification of Early and Intermediate Age-related Macular Degeneration Using OCT "en face" Presentation

    Quantification of Early and Intermediate Age-related Macular Degeneration Using OCT "en face" Presentation

    Background: Early and intermediate age-related macular degeneration (AMD) results in drusen deposits under the retinal pigment epithelium (RPE). These early stages of AMD exhibit different risks of progressing to late AMD. To date, early AMD has been classified and quantified by fundus photography. This does not appear to be sensitive enough for clinical trials studying the impact on drusen. SD-OCT with two-dimensional rendering of the segmented slices analysed allows for en face imaging of the drusen. The present trial studied the potential of quantifying early and intermediate AMD by en-face optical coherence tomography (OCT). Material and methods: Thirty-one eyes of ...

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