1. Deposits on retinal surface seen on optical coherence tomography in ocular amyloidosis

    Deposits on retinal surface seen on optical coherence tomography in ocular amyloidosis

    Objective: To investigate the tomographic features in patients with hereditary amyloidosis transthyretin (hATTR). Design: Retrospective case series and analysis of B-scan optical coherence tomography (OCT) images. Participants: A total of 120 patients (240 eyes) diagnosed with hATTR. Methods: We performed a retrospective review of the treatment history and retrospective analysis of the OCT images of patients with hATTR. The parameters analyzed were the age at which the last OCT was performed, presence of ocular amyloidosis, history of pars plana vitrectomy (PPV), systemic treatment, and genetic mutations. Two independent evaluators evaluated the OCT images for characteristic needle-shaped pattern deposits on the ...

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