1. Advances in Optical Coherence Tomography and Microscopy for endoscopic applications and functional neuroimaging (Thesis)

    Advances in Optical Coherence Tomography and Microscopy for endoscopic applications and functional neuroimaging (Thesis)
    Optical Coherence Tomography (OCT) is a developing medical imaging technology that generates micron resolution cross-sectional images of subsurface internal tissue structure in situ and in real time, without the need to remove and process specimens. Previous studies have suggested that OCT holds great potential for use in laparoscopic and endoscopic applications to detect early stage neoplastic pathologies. A minimally invasive imaging modality capable of identifying pre-malignant tissues in vivo could be used to guide conventional excisional biopsy and histology, thereby reducing sampling error and enabling earlier detection and treatment. One limitation of prior endoscopic OCT imaging methods is the inability ...
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