New technologies for optical coherence microscopy (Thesis)

According to the American Cancer Society, gastrointestinal (GI) cancers are among the most common forms of malignancies suffered today, affecting -200,000 people and causing -80,000 deaths in the United States every year. The prognosis depends heavily on the detection of early-stage lesions. The process of endoscopic surveillance, excisional biopsy, and histologic examination is the current gold standard for screening and diagnosis of many GI cancers. This process, however, is invasive, time-consuming, and can suffer from unacceptable false negative rates. Optical imaging technology that provides real-time, high-resolution imaging of human tissue in vivo with resolution at or near that ...
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