1. Hyper-reflectivity on optical coherence tomography in macular telangiectasia type 2

    Hyper-reflectivity on optical coherence tomography in macular telangiectasia type 2

    Purpose: To define, characterize and classify hyper-reflectivity on optical coherence tomography (OCT) and report its prevalence in macular telangiectasia type 2 (MacTel). Methods: In a primary cross-sectional analysis, multimodal imaging data were retrospectively analyzed. The definition of hyper-reflectivity and neovascularization on OCT followed OCT-angiography-based criteria. Eyes were graded for the presence of hyper-reflectivity and neovascularization and further categorized into three classes based on position and extent of hyper-reflectivity. In a secondary analysis, eyes were reviewed for ≥24 months using OCT-imaging. Results: 322 eyes from 161 patients were analyzed as part of the cross-sectional analysis. Hyper-reflectivity was found in 177 (55 ...

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