1. OCT angiography analysis of retinal vessel density in primary open-angle glaucoma with and without Tafluprost therapy

    OCT angiography analysis of retinal vessel density in primary open-angle glaucoma with and without Tafluprost therapy

    Primary open-angle glaucoma (POAG) is a progressive neurodegenerative disease which leads to irreversible blindness. An elevated intraocular pressure (IOP) is considered to be the main risk factor for the disease progression. It is known that retinal blood flow is altered in POAG eyes. Tafluprost, a prostaglandin analogue which lowers the IOP, has shown to also improve the retinal blood flow in animals. Methods The current study therefore evaluated the retinal vessel density in the peripapillary and macular region of POAG patients with normal IOP treated with topical Tafluprost ( n = 20) compared to surgically treated patients with normal IOP ( n = 22 ...

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