1. All Articles

    25-48 of 22331 « 1 2 3 4 5 ... 929 930 931 »
    1. Optical Coherence Tomography Angiography of the Eye (Textbook)

      Optical Coherence Tomography Angiography of the Eye (Textbook)

      Optical coherence tomography (OCT) angiography is an important new imaging modality that is already being used by ophthalmologists in retina centers worldwide. It uses motion as intrinsic contrast, thus obviating the need to inject any intravenous dye. It uses infrared light that is invisible to the patient, and only requires few seconds per scan. This makes it both easier to use and much better tolerated by patients than traditional dye-based fluorescein angiography (FA) and indocyanine green (ICG) angiography. Inside Optical Coherence Tomography Angiography of the Eye Drs. David Huang, Bruno Lumbroso, Yali Jia, and Nadia Waheed include detailed information on ...

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    2. Surgery system

      Surgery system

      A surgery system comprises a camera obtaining camera images, an OCT system, a data memory storing geometry data of a surgical tool 133 and a controller configured to identify a first portion of the tool in the camera images by object recognition using the geometry data; to determine, in the field of view, first locations where the tool is located and second locations aside of the tool; to trigger the OCT system to perform depth scans at the first and second locations; to identify a second portion 153 of the tool in the depth scans by object recognition using the ...

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    3. Immersion lens assemblies for use in optical coherence tomography systems

      Immersion lens assemblies for use in optical coherence tomography systems

      An optical coherence tomography (OCT) measurement system for precision measurement of a translucent sample is provided. The system includes an optical coherence tomography (OCT) imaging system comprising a broadband light source, a reference path with reference path length, and sample path with a beam scanning assembly and an imaging lens assembly; a sample positioning assembly including an immersion bath for positioning the translucent sample within an immersion bath; a position assembly for locating the translucent sample within a field of view (FOV) of the OCT imaging system; an immersion lens assembly associated with the imaging lens assembly configured to eliminate ...

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    4. Changes in the anterior segment after cycloplegia with a biometer using swept-source optical coherence tomography

      Changes in the anterior segment after cycloplegia with a biometer using swept-source optical coherence tomography

      The aim of this study was to investigate changes in the anterior segment of the eye after cycloplegia. A biometer combined with swept-source optical coherence tomography (SSOCT) was used for measurements. Patients with strabismus or amblyopia who underwent cycloplegia were included. The axial length, central corneal thickness, anterior chamber depth, and lens thickness were measured with the biometer–SSOCT system before and after cycloplegia. Altogether, 10 eyes of 10 patients (mean age 7.20 ± 3.08 years, range 4–14 years) were evaluated. The mean measurements before cycloplegia were 22.75 ± 0.96 mm axial length, 516 ± 33 μm central ...

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    5. Retinal Loop Vessel Captured with Optical Coherence Tomography-Angiography

      Retinal Loop Vessel Captured with Optical Coherence Tomography-Angiography

      A 50-year-old woman with a history of rheumatoid arthritis and macular hydroxychloroquine toxicity presented for a routine eye examination. An incidental loop vessel of the inferior prepapillary arteriole was readily apparent on examination (Fig 1 A ). Three-dimensional optical coherence tomography (OCT; Avanti, Optovue, Fremont, CA) demonstrated the elevation of this vessel into the vitreous (Fig 1 B ). The vessel was also captured on OCT-angiography (Fig 1 C ) with segmentation of the superficial retina and vitreous interface demonstrated by the B-scan image (inset). Retinal loop vessels are a common incidental finding on ophthalmic examination, but they can also be associated with ...

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    6. Research Associate/ Research Fellow at University of Western Australia

      Research Associate/ Research Fellow at University of Western Australia

      Job no: 499166 Work type: full-time Location: Crawley Categories: Engineering and Mathematical Sciences UWA Faculty of Engineering and Mathematical Sciences School of Electrical, Electronic and Computer Engineering 1 year fixed term appointment Level A/B position: $67,352 - $114,250 per annum The University of Western Australia (UWA) is ranked amongst the top Australian universities and a member of the prestigious Group of Eight research-intensive universities ranked among the top 100 universities in the world. About the work area You will be a member of BRITElab in the School of Electrical, Electronic and Computer Engineering within the Faculty of Engineering ...

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    7. Postdoctoral Research Scientist Position at Colgate-Palmolive Company in Piscataway New Jersey

      Postdoctoral Research Scientist Position at Colgate-Palmolive Company in Piscataway New Jersey

      Colgate-Palmolive is a leading global consumer products company, tightly focused on Oral Care, Personal Care, Home Care and Pet Nutrition. Colgate sells its products in over 200 countries and territories around the world under such internationally recognized brand names as Colgate, Palmolive, Speed Stick, Lady Speed Stick, Softsoap, Irish Spring, Protex, Sorriso, Kolynos, elmex, Tom’s of Maine, Sanex, Ajax, Axion, Fabuloso, Soupline and Suavitel, as well as Hill’s Science Diet, Hill’s Prescription Diet and Hill’s Ideal Balance. For more information about Colgate’s global business, visit the Company’s web site at http://www.colgatepalmolive.com ...

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    8. Spectroscopic imaging with spectral domain visible light optical coherence microscopy in Alzheimer’s disease brain samples

      Spectroscopic imaging with spectral domain visible light optical coherence microscopy in Alzheimer’s disease brain samples

      A visible light spectral domain optical coherence microscopy system was developed. A high axial resolution of 0.88 µm in tissue was achieved using a broad visible light spectrum (425 − 685 nm). Healthy human brain tissue was imaged to quantify the difference between white (WM) and grey matter (GM) in intensity and attenuation. The high axial resolution enables the investigation of amyloid-beta plaques of various sizes in human brain tissue and animal models of Alzheimer’s disease (AD). By performing a spectroscopic analysis of the OCM data, differences in the characteristics for WM, GM, and neuritic amyloid-beta plaques were found ...

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    9. Evaluation of Iris Melanoma with Anterior Segment Optical Coherence Tomography

      Evaluation of Iris Melanoma with Anterior Segment Optical Coherence Tomography

      Anterior segment optical coherence tomography (AS-OCT) is a relatively new imaging modality that allows assessment of anterior segment structures. AS-OCT enables the differentiation of benign and malignant tumors through the evaluation of lesion size, internal structure, degree of vascularity, and anterior and posterior surfaces. Herein, we discuss the AS-OCT findings of a patient with spindle type iridociliary melanoma diagnosed in pathologic examination.

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    10. Vitreous Punctate Spots in Eyes with Intermediate and Posterior Uveitis Using Spectral Domain Optical Coherence Tomography

      Vitreous Punctate Spots in Eyes with Intermediate and Posterior Uveitis Using Spectral Domain Optical Coherence Tomography

      Purpose:- To assess inflammatory cells in the vitreous which are seen as punctate spots on Nidek Spectral Domain Optical Coherence Tomography in eyes with intermediate and posterior uveitis. Materials and Methods:- This prospective study involved 73 eyes having intermediate and posterior uveitis which were imaged with Spectral Domain Optical Coherence Tomography (SDOCT) at baseline and 1 month after the treatment. The punctate spots were seen as hyper-reflective dots in the retina and vitreous. These were larger with greater density than the nonpunctate, irregular condensations seen in the vitreous cavity, reflecting normal age-related vitreous syneretic changes. The presence and severity of ...

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    11. Early detection of macular and peripapillary changes with spectralis optical coherence tomography in patients with prediabetes

      Early detection of macular and peripapillary changes with spectralis optical coherence tomography in patients with prediabetes

      Purpose: To compare the retina ganglion cell complex (GCC) layer and peripapillary nerve fibre layer thickness (pRNFL) in patients with prediabetes and healthy subjects analysed by spectral domain optical coherence tomography (SD-OCT). Methods: This cross-sectional and comparative study included prediabetic patients and healthy subjects. All participants underwent SD-OCT measurement of pRNFL thickness, and GCC thickness. Results: A total of 30 eyes of the 30 patients with prediabetes and 30 eyes of 30 controls were included. The overall calculated pRNFL thicknesses were similar between the prediabetic and control subjects. The GCC thickness was significantly lower in all quadrants of the inner ...

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    12. Quantitative analysis of photoreceptor layer reflectivity on en-face optical coherence tomography as an estimator of cone density

      Quantitative analysis of photoreceptor layer reflectivity on en-face optical coherence tomography as an estimator of cone density

      Background To investigate whether outer retinal reflectivity on en-face Optical coherence tomography (OCT) can be considered as an estimator of cone density measured in the same area. Methods Forty-one points of comparisons were studied in 9 eyes ( n = 6 patients) presenting maculopathies with various degrees of impairment of the photoreceptor layer. The inner segment ellipsoid zone (EZ), interdigitation zone (IZ), and retinal pigment epithelium (RPE) reflectivity were measured on coronal reconstruction of the photoreceptor layer using homemade dedicated software (Matlab, MathWorks Inc., Natick, USA). The cone metrics were measured in the same perifoveal region of interest using a high-resolution flood ...

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    13. Optical Coherence Tomography Observation of Gonio Structures during Microhook Ab Interno Trabeculotomy

      Optical Coherence Tomography Observation of Gonio Structures during Microhook Ab Interno Trabeculotomy

      Introduction . Intraoperative observation of ocular structures using microscope-integrated optical coherence tomography (iOCT) has been adopted recently. I report my initial feasibility assessment of iOCT for the incised trabecular meshwork observation during microhook ab interno trabeculotomy. Case Series . Both the nasal and temporal sides or either side of the trabecular meshwork/inner wall of Schlemm’s canal was incised more than 3 clock hours. After then, under observation using a Swan-Jacob gonioprism lens with the real-time 5-line scan mode, OCT images of the area were successfully acquired in 10 (83%) of 12 sides in nine eyes. Based on the appearance of ...

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    14. HOLE-DOOR SIGN: A Novel Intraoperative Optical Coherence Tomography Feature Predicting Macular Hole Closure

      HOLE-DOOR SIGN: A Novel Intraoperative Optical Coherence Tomography Feature Predicting Macular Hole Closure

      Purpose: To describe a novel intraoperative finding during pars plana vitrectomy for macular hole using operating microscope-integrated spectral domain optical coherence tomography that predicts the closure of macular hole. Methods: Twenty-five eyes of 25 patients with macular hole, who underwent 25-gauge pars plana vitrectomy over a period of 16 months at a tertiary eye care center by a single surgeon, were recruited in this retrospective interventional study. All eyes were assessed with intraoperative spectral domain optical coherence tomography before and after internal limiting membrane peeling. The patients were assessed in terms of best-corrected visual acuity, preoperative minimal hole diameter, and ...

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    15. Optical coherence tomography improves the results of balloon pulmonary angioplasty in inoperable chronic thrombo-embolic pulmonary hypertension

      Optical coherence tomography improves the results of balloon pulmonary angioplasty in inoperable chronic thrombo-embolic pulmonary hypertension

      A 71-year-old woman with non-operable, peripheral type chronic thrombo-embolic pulmonary hypertension (CTEPH) and with World Health Organisation (WHO) class III dyspnoea was admitted to our department for balloon pulmonary angioplasty (BPA). Right heart catheterisation confirmed pulmonary hypertension (mean pulmonary artery pressure (mPAP) 37 mm Hg, mean right atrial pressure (mRAP) 6 mm Hg, pulmonary capillary wedge pressure (PCWP) 13 mm Hg, pulmonary vascular resistance (PVR) 214 dyn · s · cm–5 and cardiac Index (CI) 4.1 l/min · m2 ) and pulmonary scintigraphy showed multiple segmental perfusion defects (segments 1, 2, 8, 9 in the left lung and 2, 3, 4 ...

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      Mentions: St. Jude Medical
    16. Diagnostic Capability of Peripapillary 3D Retinal Nerve Fiber Layer Volume for Glaucoma Using Optical Coherence Tomography Volume Scans

      Diagnostic Capability of Peripapillary 3D Retinal Nerve Fiber Layer Volume for Glaucoma Using Optical Coherence Tomography Volume Scans

      Purpose To determine the diagnostic capability of peripapillary 3-dimensional (3D) retinal nerve fiber layer (RNFL) volume measurements from spectral domain optical coherence tomography (OCT) volume scans for open angle glaucoma (OAG). Design Assessment of diagnostic accuracy. Methods Setting: Academic clinical setting. Study population : 180 patients (113 OAG and 67 normal subjects). Observation procedures : One eye per subject was included. Peripapillary 3D RNFL volumes were calculated for global, quadrant, and sector regions, using four different sized annuli. Peripapillary 2D RNFL thickness circle scans were also obtained. Main outcome measures : Area under the receiver operating characteristic curve (AUROC) values, sensitivity, specificity, positive ...

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    17. Advanced Imaging of Intracranial Atherosclerosis: Lessons from Interventional Cardiology

      Advanced Imaging of Intracranial Atherosclerosis: Lessons from Interventional Cardiology

      ntracranial atherosclerosis is a major cause of ischemic stroke. Patients with a high degree of stenosis have a significant rate of stroke despite medical therapy. Two randomized trials of stenting have failed to show benefit. Improving peri-procedural complication rates and patient selection may improve stenting outcomes. Fractional flow reserve (FFR), intravascular ultrasound (IVUS) and optical coherence tomography (OCT) are intravascular imaging techniques employed to improve patient selection and stent placement in interventional cardiology. FFR has been shown to improve cardiovascular outcomes when used in patient selection for intervention. Studies of FFR in intracranial atherosclerosis show that the measure may predict ...

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    18. Advanced analysis of domain walls in Mg doped LiNbO3 crystals with high resolution OCT

      Advanced analysis of domain walls in Mg doped LiNbO3 crystals with high resolution OCT

      The structure of domain walls (DW) in ferroelectric media is of great interest as this material is used for frequency doublers and other applications. We show that the structure of the DWs can nicely be visualized by high resolution optical coherence tomography (OCT). While the high group refractive index of lithium niobate allows a resolution much better than 1 µm, the large dispersion can blur the image and has to be compensated. Therefore, we developed an adaptive dispersion compensation algorithm based on maximizing the intensity of the DWs. By measuring a group of DWs, the mean period of the DWs ...

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    19. Optical Coherence Tomography and Stent Boost Imaging Guided Bioresorbable Vascular Scaffold Overlapping for Coronary Chronic Total Occlusion Lesion

      Optical Coherence Tomography and Stent Boost Imaging Guided Bioresorbable Vascular Scaffold Overlapping for Coronary Chronic Total Occlusion Lesion

      We report herein the optical coherence tomography (OCT) and stent boost imaging guided bioresorbable vascular scaffold (BVS) implantation for right coronary artery (RCA) chronic total occlusion (CTO) lesion. The gold standard for evaluating BVS expansion after percutaneous coronary intervention is OCT. However, stent boost imaging is a new technique that improves fluoroscopy-based assessments of stent overlapping, and the present case shows clinical usefulness of OCT and stent boost imaging guided ‘overlapping’ BVS implantation via antegrade approach for a typical RCA CTO lesion.

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    20. Optical coherence tomography to guide percutaneous treatment of coronary bifurcation disease

      Optical coherence tomography to guide percutaneous treatment of coronary bifurcation disease

      Introduction : Cardiovascular disease remains the most common cause of death worldwide. Enormous progress in the technology and applicability of percutaneous techniques to treat obstructive coronary heart disease has been made, and the number of percutaneous coronary interventions (PCI) is increasing. Coronary bifurcations are involved in a substantial number of PCIs and despite recent advances, bifurcation PCI remains a challenge in terms of immediate success and long-term outcome. Angiography has a limited capacity for showing important features of the 3 dimensional coronary vessel anatomy, position of stent struts and exact wire positions and is therefore suboptimal for guiding bifurcation PCI. Intracoronary ...

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    21. Analyzing Car Paint Through Optical Coherence Tomography

      Analyzing Car Paint Through Optical Coherence Tomography

      Researchers at the University of Liverpool in the UK have demonstrated for the first time how the medical imaging technique optical coherence tomography (OCT) could provide the car industry with a practical way to automatically analyze the distribution and characteristics of the metallic flakes in car paint. Originally a medical imaging technique Medical professionals routinely use optical coherence tomography, invented in 1991, for applications such as diagnosing eye diseases. Meanwhile, OCT is advancing into new biomedical applications and is being explored as a tool for improving manufacturing and industrial processes. The Liverpool team reports that moving their OCT technique from ...

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    22. En Face Optical Coherence Tomography Analysis to Assess the Spectrum of Perivenular Ischemia and Paracentral Acute Middle Maculopathy in Retinal Vein Occlusion

      En Face Optical Coherence Tomography Analysis to Assess the Spectrum of Perivenular Ischemia and Paracentral Acute Middle Maculopathy in Retinal Vein Occlusion

      Using en face optical coherence tomography (OCT), Falavarjani and associates recently illustrated the variability in the area of macular middle-retinal infarction (MMRI) exhibited in eyes with subtotal central retinal venous or arterial occlusion (CRVO or CRAO).1 The severity spectrum from narrow perivenular MMRI to diffuse MMRI with periarteriolar sparing was thought to reflect the extent of circulatory failure during infarct evolution. This chimes with funduscopic observations going back 40 years.

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