1. All Articles

    25-48 of 20874 « 1 2 3 4 5 ... 868 869 870 »
    1. Comparisons of Morphological Measurement Between Coronary Computed Tomography and Optical Coherence Tomography

      Comparisons of Morphological Measurement Between Coronary Computed Tomography and Optical Coherence Tomography

      The objective of this study is to evaluate the precision of semi-automated lumen boundary identification from coronary computed tomography angiography (cCTA) by current version of HeartFlow software and the impact on fractional flow reserve (FFRCT) by using optical coherence tomography (OCT) as reference standard.

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    2. Gabor fusion master slave optical coherence tomography

      Gabor fusion master slave optical coherence tomography

      This paper describes the application of the Gabor filtering protocol to a Master/Slave (MS) swept source optical coherence tomography (SS)-OCT system at 1300 nm. The MS-OCT system delivers information from selected depths, a property that allows operation similar to that of a time domain OCT system, where dynamic focusing is possible. The Gabor filtering processing following collection of multiple data from different focus positions is different from that utilized by a conventional swept source OCT system using a Fast Fourier transform (FFT) to produce an A-scan. Instead of selecting the bright parts of A-scans for each focus position ...

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    3. Choroidal neovascularization in Malattia Leventinese diagnosed using Optical Coherence Tomography Angiography

      Choroidal neovascularization in Malattia Leventinese diagnosed using Optical Coherence Tomography Angiography

      Purpose To compare Optical Coherence Tomography Angiography (OCT-A) with traditional multimodal imaging in patients with Malattia Leventinese Design Retrospective case series. Methods Eight eyes of four consecutive patients with Malattia Leventinese were retrospectively studied. All patients underwent a complete ophthalmological examination including color fundus photography, fluorescein and indocyanine green angiographies, Spectral Domain Optical Coherence Tomography and Optical Coherence Tomography Angiography. Results The choriocapillaris segmentation of OCT-A revealed the presence of a hyperflow signal corresponding to active choroidal neovascularization in 3 eyes and inactive choroidal neovascularization in one eye. Traditional multimodal imaging did not show each vascular layer and any leakage ...

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    4. Hematocrit dependence of flow signal in optical coherence tomography angiography

      Hematocrit dependence of flow signal in optical coherence tomography angiography

      The hematocrit dependence of flow signal (split-spectrum amplitude decorrelation angiography-SSADA decorrelation value) was investigated in this paper. Based on the normalized field temporal correlation function and concentration dependent particle scattering properties, the relationship between hematocrit and flow signal was analytically derived. Experimental verification of the relationship was performed with custom-designed microfluidic chips and human blood with 45%, 40% and 32% hematocrit. It was found that, in large flow channels and blood vessels, the normal hematocrit is near the decorrelation saturation point and therefore a change in hematocrit has little effect on the SSADA decorrelation value (flow signal). However, in narrow ...

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    5. RETINAL DETACHMENT ASSOCIATED WITH PERIPAPILLARY STAPHYLOMA IMAGED WITH SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY

      RETINAL DETACHMENT ASSOCIATED WITH PERIPAPILLARY STAPHYLOMA IMAGED WITH SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY

      Purpose: To examine a rhegmatogenous retinal detachment (RRD) associated with a peripapillary staphyloma with swept source optical coherence tomography (SS-OCT) before and after vitrectomy and circumferential photocoagulation. Methods: The SS-OCT images including the montage images of two patients with a RRD associated with peripapillary staphylomas were analyzed. A 34-year-old woman (Case 1) and a 70-year-old woman (Case 2) both noticed temporal visual field defects in their left eyes. Ophthalmoscopy showed a retinal detachment in the nasal quadrant without any peripheral breaks in both patients. The best-corrected visual acuity was 20/20 with -8.5 diopters in Case 1 and 20 ...

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    6. Ex Vivo Assessment of Coronary Atherosclerotic Plaque by Grating-Based Phase-Contrast Computed Tomography: Correlation With Optical Coherence Tomography

      Ex Vivo Assessment of Coronary Atherosclerotic Plaque by Grating-Based Phase-Contrast Computed Tomography: Correlation With Optical Coherence Tomography

      Objectives: The aim of this study was to determine the diagnostic accuracy of grating-based phase-contrast computed tomography (gb-PCCT) to classify and quantify coronary vessel characteristics in comparison with optical coherence tomography (OCT) and histopathology in an ex vivo setting. Materials and Methods: After excision from 5 heart specimens, 15 human coronary arteries underwent gb-PCCT examination using an experimental imaging setup consisting of a rotating molybdenum anode x-ray tube, a Talbot-Lau grating interferometer, and a single photon counting detector. Subsequently, all vessels were imaged by OCT and histopathologically processed. Optical coherence tomography, gb-PCCT, and histopathology images were manually matched using anatomical ...

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    7. Optical coherence tomography of macular atrophy associated with microcephaly and presumed intrauterine Zika virus infection

      Optical coherence tomography of macular atrophy associated with microcephaly and presumed intrauterine Zika virus infection

      This case report describes the retinal optical coherence tomography (OCT) findings in a microcephalic infant with macular atrophy presumably caused by intrauterine Zika virus infection. OCT demonstrated atrophy of the outer retinal layers and choriocapillaris, including the outer nuclear layer and ellipsoid zone, associated with retinal pigment epithelium hyper-reflectivity and increased OCT penetration into deeper layers of the choroid and sclera. A major concern associated with this infection is the apparent increased incidence of microcephaly in fetuses born to mothers infected with the Zika virus. It is becoming increasingly difficult to ignore the upsurge in congenital microcephaly observed in Brazil ...

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    8. Medical Imaging Innovator Christine Hendon Wins Presidential Honor

      Medical Imaging Innovator Christine Hendon Wins Presidential Honor

      Christine Hendon , assistant professor of electrical engineering at Columbia Engineering , has won the Presidential Early Career Award (PECASE), the highest honor the U.S. government gives to young scientists and engineers. Hendon, who develops innovative medical imaging instruments for use in surgery and breast cancer detection, is one of 102 researchers from across the nation named by President Obama on January 9. “I congratulate these outstanding scientists and engineers on their impactful work,” President Obama said. “These innovators are working to help keep the United States on the cutting edge, showing that federal investments in science lead to advancements that ...

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    9. Vascular Features of Full-Thickness Macular Hole by OCT Angiography

      Vascular Features of Full-Thickness Macular Hole by OCT Angiography

      BACKGROUND AND OBJECTIVE: To compare the features of cystoid cavities associated with full-thickness macular hole (FTMH) imaged with optical coherence tomography angiography (OCTA) and en face OCT. PATIENTS AND METHODS: Prospective, observational, cross-sectional study. Clinical practice and observation. Thirteen patients (13 eyes) with FTMH were evaluated before vitrectomy. All eyes underwent OCTA or en face OCT imaging. RESULTS: There was a statistically significant positive correlation between groups for the total cavity area in both inner nuclear layer ( P < .001; r 2 = 0.82) and outer plexiform and Henle fiber layer complex ( P < .001; r 2 = 0.84). CONCLUSIONS: OCTA and ...

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    10. Choroidal Osteoma Deossification Visualized by Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography

      Choroidal Osteoma Deossification Visualized by Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography

      Choroidal osteoma (CO) is a rare, benign ossifying lesion of the choroid found in otherwise healthy patients. Although associated with good visual prognosis, tumor deossification in choroidal osteoma has been linked with vision loss, presumably due to overlying photoreceptor degeneration. Here the authors present a case of CO in an elderly male demonstrating tumor deossification and photoreceptor atrophy during a 3-year follow-up using enhanced depth imaging optical coherence tomography (EDI-OCT). Visual acuity was maintained due to the tumor's noncentral location. Patients with CO should undergo regular imaging with EDI-OCT to screen for tumor deossification and impending vision loss.

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    11. Noise stochastic corrected maximum a posteriori estimator for birefringence imaging using polarization-sensitive optical coherence tomography

      Noise stochastic corrected maximum a posteriori estimator for birefringence imaging using polarization-sensitive optical coherence tomography

      This paper presents a noise-stochastic corrected maximum a posteriori estimator for birefringence imaging using Jones matrix optical coherence tomography. The estimator described in this paper is based on the relationship between probability distribution functions of the measured birefringence and the effective signal to noise ratio (ESNR) as well as the true birefringence and the true ESNR. The Monte Carlo method is used to numerically describe this relationship and adaptive 2D kernel density estimation provides the likelihood for a posteriori estimation of the true birefringence. Improved estimation is shown for the new estimator with stochastic model of ESNR in comparison to ...

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    12. Post-Doctoral Research Associate Positions at University of Illinois at Urbana-Champaign

      Post-Doctoral Research Associate Positions at University of Illinois at Urbana-Champaign

      Beckman Institute for Advanced Science and Technology University of Illinois at Urbana-Champaign The Biophotonics Imaging Laboratory and the Center for Optical Molecular Imaging at the Beckman Institute for Advanced Science and Technology on the campus of the University of Illinois at Urbana-Champaign have immediate openings for two post-doctoral research associates in the area of optical imaging systems for biomedical applications. Headed and directed by Prof. Stephen Boppart, the Biophotonics Imaging Laboratory and the Center for Optical Molecular Imaging are dynamic and productive interdisciplinary research and training environments focused on developing novel optical biomedical imaging technologies, translating them into clinical applications ...

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    13. Heidelberg Engineering and Gauss Medical Corporation Establish an Ophthalmic Healthcare IT Joint Venture in China

      Heidelberg Engineering and Gauss Medical Corporation Establish an Ophthalmic Healthcare IT Joint Venture in China

      The joint venture company, Gauss Infomed, will offer Picture Archiving and Communication Systems (PACS) and Electronic Medical Record (EMR) software, along with other related product solutions for the ophthalmology healthcare IT market. Gauss Infomed will operate out of Beijing and through a local network of offices to deliver its services across the entire country. “China is a fast-growing market and it is of great importance to our company” “The establishment of this joint venture with Heidelberg Engineering comes at a time of growing demand for advanced ophthalmic IT solutions in China,” said Mr. Liu Xidong, Chairman and CEO of Gauss ...

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    14. Optical coherence tomography assessment of a complex bifurcation lesion treated with double kissing Crush technique: A case report

      Optical coherence tomography assessment of a complex bifurcation lesion treated with double kissing Crush technique: A case report

      The DEFINITION (Impact of the complexity of bifurcation lesions treated with drug-eluting stents) study has provided a novel classification to evaluate the complexity of coronary bifurcation lesion according to coronary angiography, but angiographic imaging due to its low resolution and inherited limitation may result in an inaccurate adjudication. We used optical coherence tomography (OCT) to further evaluate the coronary characteristics in a patient with “simple” bifurcation lesion which was classified by the DEFINITION criteria. However, a “complex” bifurcation lesion was defined and confirmed according to the OCT results. A double kissing Crush stenting approach was adopted to treat this “complex ...

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    15. University of Alabam Receives NIH Grant for In Vivo Ultrastruture of Chorioretinal Disease

      University of Alabam Receives NIH Grant for In Vivo Ultrastruture of Chorioretinal Disease

      University of Alabam at Birmingham Receives a 2017 NIH Grant for $330,750 for In Vivo Ultrastruture of Chorioretinal Disease. The principal investigator is Yuhua Zhang. The program began in 2015 and ends in 2019. Below is a summary of the proposed work. Age-related macular degeneration (AMD) is a leading cause of vision loss in more than 10 million older Americans. For decades, AMD has been characterized by accumulation of extracellular lesions called drusen on the inner surface of Bruch's membrane (BrM), posterior to the retinal pigment epithelium (RPE), in a compartment called the sub-RPE space. Drusen are now ...

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    16. Beth Isreal Deaconess Medical Center Receives Grant for Intravascular Molecular-Structural Imaging of Coronary Stent Pathobiology

      Beth Isreal Deaconess Medical Center Receives Grant for Intravascular Molecular-Structural Imaging of Coronary Stent Pathobiology

      Beth Isreal Deaconess Medical Center Receives a 2017 NIH Grant for $164,376 for Intravascular Molecular-Structural Imaging of Coronary Stent Pathobiology. The principal investigator is Eric Osborn. The program began in 2017 and ends in 2020. Below is a summary of the propose work. Dr. Eric Osborn is an early career faculty member at Beth Israel Deaconess Medical Center (BIDMC) and Massachusetts General Hospital (MGH), and an Instructor in Medicine at Harvard Medical School, Boston, Massachusetts. He is a graduate of the MD-PhD program at Harvard Medical School and Massachusetts Institute of Technology, and has completed clinical training in medicine ...

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    17. The University of Houston Receives NIH Grant for Optical Coherence Tomography to Study Effect of Poly-Drug Exposure on Fetal Brain Development

      The University of Houston Receives NIH Grant for Optical Coherence Tomography to Study Effect of Poly-Drug Exposure on Fetal Brain Development

      The University of Houston Receives a 2017 NIH Grant for $311,241 for Optical Coherence Tomography to Study Effect of Poly-Drug Exposure on Fetal Brain Development. The principal investigator is Kirll Larin. The program began in 2016 and ends in 2020. Below is a summary of the proposed work. The overall objective of this study is to develop an optical coherence tomography (OCT) based high- resolution mouse embryonic brain imaging and analysis approach, and to use this method in correlation with molecular analysis to understand the interplay between ethanol (EtOH) and nicotine (NIC) effects on embryonic brain development. Maternal exposures ...

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    18. UCDavis Receives NIH Grant for Properties of Photoreceptoers and Muller Cells Investigated with AO-OCT

      UCDavis Receives NIH Grant for Properties of Photoreceptoers and Muller Cells Investigated with AO-OCT

      The University of California at Davis Receives a 2017 NIH Grant for $97,834 for Properties of Photoreceptoers and Muller Cells Investigated with AO-OCT. The principal investigator is Ravi Jonnal. The program began in 2016 and ends in 2017. Below is a summary of the proposed work. The research proposed for this award will examine functional and structural properties of single cells in the human retina. The three Aims will link the candidate's scientific background and career plans to study the human retina using a combination of adaptive optics (AO) and optical coherence tomography (OCT) which provide high lateral ...

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    19. University of Miami Receives NIH Grant for Endothelium/Descemet's Membrane Complex Optical Tomography.

      University of Miami Receives NIH Grant for Endothelium/Descemet's Membrane Complex Optical Tomography.

      University of Miami Receives a 2017 NIH Grant for $227,722 for Endothelium/Descemet's Membrane Complex Optical Tomography. The principal investigator is Mohamed Shousha. The program began in 2016 and ends in 2020. Below is a summary of the proposed work. More than 50% of corneal transplants, the most common form of solid organ transplantation, are performed to restore vision lost secondary to corneal endothelial failure. More than 25% of those transplants will eventually fail and endothelial cell rejection leading to failure is the single most important cause. The key to protec the endothelium is the early and accurate ...

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    20. Geometric & radiometric vignetting associated with a 72-facet, off-axis, polygon mirror for swept source optical coherence tomography (SS-OCT)

      Geometric & radiometric vignetting associated with a 72-facet, off-axis, polygon mirror for swept source optical coherence tomography (SS-OCT)

      Optical Coherence Tomography (OCT) has a broad range of applications in 2D and volumetric imaging of micron scale structures typically used on inaccessible objects such as the retina of the eye. This report focuses on Swept Source OCT (SS-OCT), favoured for its faster scanning speeds and therefore faster data acquisition (highly favourable when imaging live patients). SS-OCT relies on the scanning of a narrow laser line at speeds typically in excess of 100 kHz. We have employed Zemax TM ray tracing software to simulate one method of splitting the spectrum of a broadband, near-infrared source, into its component wavelengths by ...

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    21. Plaque erosion causing ST-segment elevation myocardial infarction: report of an optical coherence tomography-documented case and concise literature review

      Plaque erosion causing ST-segment elevation myocardial infarction: report of an optical coherence tomography-documented case and concise literature review

      A 61-year-old man presented to the Emergency Room of a referring hospital with anterior ST-segment elevation myocardial infarction (STEMI) and was immediately treated by antiplatelet therapy and transferred to our hospital to perform a primary percutaneous coronary intervention (PCI)...

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      Mentions: Rocco Vergallo
    22. Advantages of Anterior Segment Optical Coherence Tomography Evaluation of the Kayser-Fleischer Ring in Wilson Disease

      Advantages of Anterior Segment Optical Coherence Tomography Evaluation of the Kayser-Fleischer Ring in Wilson Disease

      Purpose: To present anterior segment optical coherence tomography (AS-OCT) findings of the Kayser-Fleischer (KF) ring in Wilson disease (WD) and to discuss the potential advantages of evaluating the KF ring by AS-OCT. Methods: This is a retrospective case series of 7 patients with WD with KF rings seen in our institute during the study period (August 2015 to June 2016). All patients underwent slit-lamp examination of the cornea and AS-OCT (Optovue RTVue Premier). In 2 patients, the length of the KF ring was measured using the gray scale of AS-OCT. Results: The KF ring on the gray scale of AS-OCT ...

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    25-48 of 20874 « 1 2 3 4 5 ... 868 869 870 »
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