1. All Articles

    1-24 of 19367 1 2 3 4 ... 805 806 807 »
    1. Anterior Segment Optical Coherence Tomography of Patients With Late-Onset Tunnel Fungal Infections With Endophthalmitis After Cataract Surgery

      Anterior Segment Optical Coherence Tomography of Patients With Late-Onset Tunnel Fungal Infections With Endophthalmitis After Cataract Surgery

      Purpose: To report the use of anterior segment optical coherence tomography for characterization of late-onset tunnel fungal infections with endophthalmitis after cataract surgery. Methods: Case reports. Results: A 77-year-old female (case 1) and a 76-year-old male (case 2) who received cataract surgery 15 and 1 year before their initial visits, respectively, were treated with topical steroids based on a diagnosis of uveitis, because they showed growing white lesions on the upper iris and beneath the cataract scleral wound. Irrigation of the anterior chambers and removal of the white lesions were performed in each case, and microbiological tests were positive for ...

      Read Full Article
    2. Mechanical properties of the everolimus-eluting bioresorbable vascular scaffold compared to the metallic everolimus-eluting stent

      Mechanical properties of the everolimus-eluting bioresorbable vascular scaffold compared to the metallic everolimus-eluting stent

      Background Everolimus-eluting bioresorbable vascular scaffolds (BVS) represent an innovative treatment option for coronary artery disease. Clinical and angiographic results seem promising, however, data on its immediate procedural performance are still scarce. The aim of our study was to assess the mechanical properties of BVS by Optical Coherence Tomography (OCT) in clinical routine. Methods Post-implantation OCT images of 40 BVS were retrospectively compared to those of 40 metallic everolimus-eluting stents (EES). Post-procedural device related morphological features were assessed. This included incidences of gross underexpansion and the stent eccentricity index (SEI, minimum/maximum diameter) as a measure for focal radial strength. Results ...

      Read Full Article
    3. Use of Anterior Segment Optical Coherence Tomography to Determine the Position of the Horizontal and Vertical Extraocular Muscles

      Use of Anterior Segment Optical Coherence Tomography to Determine the Position of the Horizontal and Vertical Extraocular Muscles

      Pediatric ophthalmologists are often faced with a patient who has had previous strabismus surgery without a definitive history or records to confirm what specific surgery was performed. In planning further surgery, the pediatric ophthalmologist is often required to evaluate the previous location of the extraocular muscles. This is usually done while the patient is undergoing the surgery. Once the locations of the muscles are documented, further surgery can be performed using the patient's postoperative measurements. Having the anterior segment optical coherence tomography as a preoperative guide to inform the pediatric ophthalmologist where the previous operative muscles are located provides ...

      Read Full Article
    4. Anterior Segment Optical Coherence Tomography of the Horizontal and Vertical Extraocular Muscles With Measurement of the Insertion to Limbus Distance

      Anterior Segment Optical Coherence Tomography of the Horizontal and Vertical Extraocular Muscles With Measurement of the Insertion to Limbus Distance

      PURPOSE: To assess the possibility of determining the insertion distance from the limbus of horizontal and vertical extraocular rectus muscles with anterior segment optical coherence tomography (AS-OCT). METHODS: The right eyes of 46 patients underwent AS-OCT. The horizontal and vertical extraocular rectus muscle insertion distances from the limbus were measured in a masked fashion by two pediatric ophthalmologists. RESULTS: Forty-two lateral rectus, 43 medial rectus, 35 inferior rectus, and 40 superior rectus muscles of the right eyes of 46 patients were included. Insertion to limbus measurements (mean ± SD) were as follows: lateral rectus = mean 6.8 ± 0.7 mm, range ...

      Read Full Article
    5. Impact of stent platform on longitudinal stent deformation: an in vivo frequency domain optical coherence tomography study

      Impact of stent platform on longitudinal stent deformation: an in vivo frequency domain optical coherence tomography study

      Recently, longitudinal coronary stent deformation has been highlighted as a possible cause of drug-eluting stent failure. Although bench tests and in vivo studies have demonstrated difference in longitudinal stent strength among the stents with different platforms, its clinical impact is still unknown. Furthermore, it is unknown if modified stent platform favorably affect the incidence of stent deformation. The aim of this study was to investigate the longitudinal deformation of the everolimus-eluting stents (EES) with different stent platforms by using frequency domain optical coherence tomography (FD-OCT). Seventy-eight lesions treated with EES (Xience Prime: n = 26, Promus element: n = 29, Promus premier ...

      Read Full Article
    6. Optical coherence tomography for embryonic imaging: a review

      Optical coherence tomography for embryonic imaging: a review

      Embryogenesis is a highly complex and dynamic process, and its visualization is crucial for understanding basic physiological processes during development and for identifying and assessing possible defects, malformations, and diseases. While traditional imaging modalities, such as ultrasound biomicroscopy, micro-magnetic resonance imaging, and micro-computed tomography, have long been adapted for embryonic imaging, these techniques generally have limitations in their speed, spatial resolution, and contrast to capture processes such as cardiodynamics during embryogenesis. Optical coherence tomography (OCT) is a noninvasive imaging modality with micrometer-scale spatial resolution and imaging depth up to a few millimeters in tissue. OCT has bridged the gap between ...

      Read Full Article
    7. OCT angiography quantitates differences in lesion responses to anti-VEGF therapy

      OCT angiography quantitates differences in lesion responses to anti-VEGF therapy

      Type 1 neovascular lesions are large, mature and resistant to anti-VEGF therapy, whereas type 3 lesions are small capillary tufts that are highly responsive to just one anti-VEGF injection, according to a study presented here. Using OCT angiography, David Sarraf, MD, and colleagues looked at the quantitative and qualitative effects of anti-VEGF therapy in both types of lesions in cases of age-related macular degeneration. “In this particular study, we wanted to look at the microvascular response of these lesions to anti-VEGF therapy and quantitate the reduction in area and density of these lesions,” Sarraf said at the American Ophthalmological Society ...

      Read Full Article
      Mentions: Optovue
    8. SPECTRAL DOMAIN-OPTICAL COHERENCE TOMOGRAPHY IMAGE CONTRAST AND BACKGROUND COLOR SETTINGS INFLUENCE IDENTIFICATION OF RETINAL STRUCTURES

      SPECTRAL DOMAIN-OPTICAL COHERENCE TOMOGRAPHY IMAGE CONTRAST AND BACKGROUND COLOR SETTINGS INFLUENCE IDENTIFICATION OF RETINAL STRUCTURES

      Purpose: To evaluate image contrast and color setting on assessment of retinal structures and morphology in spectral-domain optical coherence tomography. Methods: Two hundred and forty-eight Spectralis spectral-domain optical coherence tomography B-scans of 62 patients were analyzed by 4 readers. B-scans were extracted in 4 settings: W + N = white background with black image at normal contrast 9; W + H = white background with black image at maximum contrast 16; B + N = black background with white image at normal contrast 12; B + H = black background with white image at maximum contrast 16. Readers analyzed the images to identify morphologic features. Interreader correlation was ...

      Read Full Article
    9. Spectral domain optical coherence tomography and B-scan ultrasonography in the evaluation of retinal tears in acute, incomplete posterior vitreous detachment

      Spectral domain optical coherence tomography and B-scan ultrasonography in the evaluation of retinal tears in acute, incomplete posterior vitreous detachment

      Background The purpose of this study was to evaluate the extension and traction effects of posterior vitreous detachment (PVD) complicated with retinal tears using spectral domain optical coherence tomography (OCT) and B-scan ultrasonography. Methods Complete ophthalmological examination, B-scan ultrasonography and spectral domain OCT were performed in patients with acute PVD and retinal tears. Vitreous detachment was classified as complete or incomplete, based on extent of posterior pole or peripheral vitreous detachment. Retinal tear location and persistent traction on the retinal flap was evaluated with B-scan ultrasonography and OCT. Categorical data were evaluated with Fisher’s exact test. Statistical significance was ...

      Read Full Article
    10. Outer retinal deformity detected by optical coherence tomography in eyes with foveal hypoplasia

      Outer retinal deformity detected by optical coherence tomography in eyes with foveal hypoplasia

      Purpose To investigate the relationship between vision and foveal maturity, especially in foveal hypoplasia exhibiting severe structural immaturity. Methods This retrospective observational case series included 42 eyes of 23 patients (mean age, 7.0 ± 5.0 years; 9 patients with foveal hypoplasia as an isolated entity and 14 patients with aniridia). A complete ophthalmic examination included measurement of best-corrected visual acuity (BCVA) and spectral-domain optical coherence tomography (SD-OCT). The sensory retina, ganglion cell complex (GCC), and outer retinal layers, including Henle’s fiber layer (HFL), were measured and analyzed. Results Using SD-OCT images, eyes were classified as having a differentiated ...

      Read Full Article
    11. Associations between the Framingham Risk Score and coronary plaque characteristics as assessed by three-vessel optical coherence tomography

      Associations between the Framingham Risk Score and coronary plaque characteristics as assessed by three-vessel optical coherence tomography

      Objectives: This study sought to explore the association between the Framingham Risk Score (FRS) and coronary plaque characteristics assessed by optical coherence tomography (OCT) imaging. Background: Clinical prediction models are useful for identifying high-risk patients. However, coronary events often occur in individuals estimated to be at low risk. Methods: A total of 254 patients with coronary artery disease who underwent three-vessel OCT were divided into tertiles according to FRS. Nonculprit plaque characteristics were compared among the three groups. Results: A total of 663 plaques were analyzed. FRS was significantly associated with calcification [37% (low FRS) vs. 46% (intermediate FRS) vs ...

      Read Full Article
    12. Serial “En Face” Optical Coherence Tomography Imaging Of Slowly Resorbing Subretinal Fluid After Pneumatic Retinopexy

      Serial “En Face” Optical Coherence Tomography Imaging Of Slowly Resorbing Subretinal Fluid After Pneumatic Retinopexy

      Purpose: To describe the use and utility of serial “en face” C-scan optical coherence tomography in following the postoperative subretinal fluid status in a patient after pneumatic retinopexy treatment of a rhegmatogenous retinal detachment. Method: Case study. Results: Serial “en face” optical coherence tomography imaging enhanced postoperative follow-up of persistent subretinal fluid, demonstrating its spontaneous disappearance over time. Conclusion: Previous studies showed that subretinal fluid persists in a large proportion of patients after rhegmatogenous retinal detachment repair (especially in those with a chronic component). “En face” optical coherence tomography imaging is a valuable tool for demonstrating postoperative fluid status and ...

      Read Full Article
    13. The APOSTEL recommendations for reporting quantitative optical coherence tomography studies

      The APOSTEL recommendations for reporting quantitative optical coherence tomography studies

      Objective: To develop consensus recommendations for reporting of quantitative optical coherence tomography (OCT) study results. Methods: A panel of experienced OCT researchers (including 11 neurologists, 2 ophthalmologists, and 2 neuroscientists) discussed requirements for performing and reporting quantitative analyses of retinal morphology and developed a list of initial recommendations based on experience and previous studies. The list of recommendations was subsequently revised during several meetings of the coordinating group. Results: We provide a 9-point checklist encompassing aspects deemed relevant when reporting quantitative OCT studies. The areas covered are study protocol, acquisition device, acquisition settings, scanning protocol, funduscopic imaging, postacquisition data selection ...

      Read Full Article
    14. Perimeter Medical Imaging Receives FDA Clearance for OTISTM Optical Tissue Imaging System

      Perimeter Medical Imaging Receives FDA Clearance for OTISTM Optical Tissue Imaging System

      Perimeter Medical Imaging, Inc., an innovative medical imaging company whose mission is to revolutionize tissue removal surgery for surgeons and patients, today announced receipt of U.S. Food and Drug Administration (FDA) 510(k) clearance for its OTIS TM 1.0 Optical Coherence Tomography System. The OTIS™ provides high-resolution, real-time imaging of the periphery of excised tissue, enabling clinicians to visualize sub-surface structures up to 2 mm below the surface. These sub-surface structures would otherwise not be evident until days – and often weeks – later when conventional histology slides are available for review. Dr. Ted James, Medical Director of Skin & Soft ...

      Read Full Article
    15. Retroreflective-type Janus microspheres as a novel contrast agent for enhanced optical coherence tomography

      Retroreflective-type Janus microspheres as a novel contrast agent for enhanced optical coherence tomography

      Working principle and SEM image of Janus microsphere (top). Enhanced OCT imaging (bottom) of Janus microspheres in zebrafish stomach (blue dash line) and sinusoids (green arrows) of nude liver. Optical coherence tomography (OCT) is a well-developed technology that utilizes near-infrared light to reconstruct three-dimensional images of biological tissues with micrometer resolution. Improvements of the imaging contrast of the OCT technique are able to further widen its extensive biomedical applications. In this study, Janus microspheres were developed and used as a positive contrast agent for enhanced OCT imaging. Phantom and ex vivo liver tissue experiments as well as in vivo animal ...

      Read Full Article
    16. Outer Retinal Layers Alterations in Chronic Central Serous Chorioretinopathy: Spectral Domain-OCT and Fundus Autofluorescence Findings

      Outer Retinal Layers Alterations in Chronic Central Serous Chorioretinopathy: Spectral Domain-OCT and Fundus Autofluorescence Findings

      Purpose To document alteration of the outer retinal layers and fundus autofluorescence (FAF) change in eyes with chronic central serous chorioretinopathy (CSCR). Methods Seventeen eyes of fifteen patients diagnosed with chronic CSCR from January 2014 to March 2015 with at least 6 months of follow-up and no history of surgery were enrolled in this study. Morphologic alterations in the retinal pigment epithelium (RPE), the photoreceptor inner segment/outer segment (IS/OS) junction layer, and the outer retina were evaluated by Spectral domain optical coherence tomography (SD-OCT). The FAF images were obtained via Heidelberg Retina Angiogram using a view mode of ...

      Read Full Article
    17. Recanalization of Organized Thrombi Demonstrated by Coronary CT Angiography Compared With OCT

      Recanalization of Organized Thrombi Demonstrated by Coronary CT Angiography Compared With OCT

      Recanalization of organized thrombi (ROT) is a rarely recognized disease histologically characterized by older coronary thrombi forming small lumens or endothelium-lined neovascular channels within thrombus. Optical coherence tomography (OCT) is the method of choice for diagnosis and shows signal-rich, high backscattered septa dividing the lumen into multiple small channels that communicate with each other (1) . Computed tomography angiography (CTA) in the longitudinal and cross-sectional planes may demonstrate the ROT by showing multiple small contrast-filled spaces divided by low-attenuation septa in agreement with the OCT findings (Figures Figure 1 and Figure 2 ). Given its rarity, CTA findings of ROT have not ...

      Read Full Article
    18. An All-Fiber-Optic Combined System of Noncontact Photoacoustic Tomography and Optical Coherence Tomography

      An All-Fiber-Optic Combined System of Noncontact Photoacoustic Tomography and Optical Coherence Tomography

      We propose an all-fiber-based dual-modal imaging system that combines noncontact photoacoustic tomography (PAT) and optical coherence tomography (OCT). The PAT remotely measures photoacoustic (PA) signals with a 1550-nm laser on the surface of a sample by utilizing a fiber interferometer as an ultrasound detector. The fiber-based OCT, employing a swept-source laser centered at 1310 nm, shares the sample arm of the PAT system. The fiber-optic probe for the combined system was homemade with a lensed single-mode fiber (SMF) and a large-core multimode fiber (MMF). The compact and robust common probe is capable of obtaining both the PA and the OCT ...

      Read Full Article
    19. The Repeatability of Retinal Layer Thickness Measurements with Spectral-Domain Optical Coherence Tomography in Normal Eyes

      The Repeatability of Retinal Layer Thickness Measurements with Spectral-Domain Optical Coherence Tomography in Normal Eyes

      Purpose To evaluate the repeatability of retinal layer thickness measurements in normal eyes imaged using spectral domain optical coherence tomography (SD-OCT). Methods Sixty-eight eyes of 34 healthy subjects were enrolled in this study. Imaging was performed 4 times using 9 × 9 mm macular scans with SD-OCT (RS 3000 Advance HD OCT, NIDEK, Gamagori, Japan) at the same visit by an experienced examiner. After automatic retinal segmentation (layering) in 5 layers, the thickness of each layer was calculated. Macular thickness of 9 Early Treatment of Diabetic Retinopathy Study (ETDRS)–like regions was obtained. Repeatability for each of the 9 subfield areas ...

      Read Full Article
      Mentions: Nidek
    20. Assessment of Vascular Response after Stent Implantation by Intracoronary Optical Coherence Tomograph

      Assessment of Vascular Response after Stent Implantation by Intracoronary Optical Coherence Tomograph

      Optical coherence tomography (OCT) is a high resolution (10-20 μm) imaging modality that provides microscopic visualization of the coronary artery including vascular response after stent implantation. Compared to conventional intravascular ultrasound, OCT can more clearly identify findings immediately after stent implantation, such as tissue protrusion, stent edge dissection, and incomplete stent strut apposition. Furthermore, OCT allows clinicians to accurately assess the late acquired stent malapposition and strut coverage which could be a surrogate marker for stent thrombosis after drug-eluting stent (DES) implantation. OCT can evaluate not only the extent and amount of neointima but also the tissue characteristics of neointimal ...

      Read Full Article
    21. In vivo assessment of optical properties of basal cell carcinoma and differentiation of BCC subtypes by high-definition optical coherence tomography

      In vivo assessment of optical properties of basal cell carcinoma and differentiation of BCC subtypes by high-definition optical coherence tomography

      High-definition optical coherence tomography (HD-OCT) features of basal cell carcinoma (BCC) have recently been defined. We assessed in vivo optical properties (IV-OP) of BCC, by HD-OCT. Moreover their critical values for BCC subtype differentiation were determined. The technique of semi-log plot whereby an exponential function becomes linear has been implemented on HD-OCT signals. The relative attenuation factor ( µ raf ) at different skin layers could be assessed. . IV-OP of superficial BCC with high diagnostic accuracy (DA) and high negative predictive values (NPV) were (i) decreased µ raf in lower part of epidermis and (ii) increased epidermal thickness (E-T). IV-OP of nodular BCC with ...

      Read Full Article
    22. Optical Coherence Tomography Classification and Correlation With Tuberous Sclerosis Complex

      Optical Coherence Tomography Classification and Correlation With Tuberous Sclerosis Complex

      Purpose: To propose a classification of retinal astrocytic hamartoma based on spectral domain optical coherence tomography and correlate each class with systemic manifestations of tuberous sclerosis complex. Methods: Retrospective chart review conducted at four international referral medical retina centers. There were 43 consecutive patients with an established diagnosis of tuberous sclerosis complex based on presence of at least 2 major or 1 major and 2 minor features of the diagnostic criteria. Clinical and spectral domain optical coherence tomography features regarding retinal astrocytic hamartoma were documented. Results: The mean patient age at presentation was 16.2 years. The retinal astrocytic hamartoma ...

      Read Full Article
    1-24 of 19367 1 2 3 4 ... 805 806 807 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Popular Articles

  3. Optical Coherence Tomography News

    See all Optical Coherence Tomography News articles
  4. Organizations in the News

    1. (601 articles) Harvard University
    2. (511 articles) Massachusetts General Hospital
    3. (504 articles) Massachusetts Institute of Technology
    4. (477 articles) National Institutes of Health
    5. (380 articles) Duke University
    6. (333 articles) Johns Hopkins University
    7. (332 articles) University of Miami
    8. (329 articles) Medical University of Vienna
    9. (305 articles) University of Southern California
    10. (296 articles) FDA
  5. People in the News

    1. (345 articles) James G. Fujimoto
    2. (234 articles) Joseph A. Izatt
    3. (231 articles) David Huang
    4. (215 articles) Ruikang K. Wang
    5. (192 articles) Stephen A. Boppart
    6. (190 articles) Guillermo J. Tearney
    7. (182 articles) Adrian G. Podoleanu
    8. (181 articles) Zhongping Chen
    9. (168 articles) Patrick W. Serruys
    10. (166 articles) Brett E. Bouma
  6. OCT Companies in the News

    1. (1443 articles) Carl Zeiss Meditec
    2. (761 articles) St. Jude Medical
    3. (557 articles) Heidelberg Engineering
    4. (473 articles) Optovue
    5. (327 articles) Volcano Corporation
    6. (321 articles) Topcon Medical Systems
    7. (232 articles) Michelson Diagnostics
    8. (203 articles) Bioptigen
    9. (180 articles) Thorlabs
    10. (138 articles) Axsun Technologies