1. All Articles

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    1. Analysis of a spinning polygon wavelength swept laser

      Analysis of a spinning polygon wavelength swept laser

      It has been known for quite some time that spinning polygon, and similar, swept lasers used in OCT favor the short to long wavelength sweep direction because of four wave mixing in the gain medium. Here we have reformulated the problem in the time domain and show experimentally and through numerical simulation that these lasers are pulsed. The emitted pulses modulate the gain medium refractive index to red shift the light. Instead of new wavelengths being built up slowly from spontaneous emission, each pulse hops to a longer wavelength by nonlinear means, tracking the tunable filter. This allows high speed ...

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    2. Change in drusen area over time compared using spectral-domain optical coherence tomography and color fundus imaging

      Change in drusen area over time compared using spectral-domain optical coherence tomography and color fundus imaging

      Purpose. To investigate the relationship between drusen areas measured with color fundus images (CFIs) and those with spectral-domain optical coherence tomography (SDOCT). Methods. Forty-two eyes from thirty patients with drusen in the absence of geographic atrophy were recruited to a prospective study. Digital color fundus images and SDOCT images were obtained at baseline and at follow-up visits at 3 and 6 months. Registered, matched circles centered on the fovea with diameters of 3 mm and 5 mm were identified on both CFIs and SDOCT images. Spectral-domain OCT drusen measurements were obtained using a commercially available proprietary algorithm. Drusen boundaries on ...

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    3. Full wave model of image formation in optical coherence tomography applicable to general samples

      Full wave model of image formation in optical coherence tomography applicable to general samples

      We demonstrate a highly realistic model of optical coherence tomography, based on an existing model of coherent optical microscopes, which employs a full wave description of light. A defining feature of the model is the decoupling of the key functions of an optical coherence tomography system: sample illumination, light-sample interaction and the collection of light scattered by the sample. We show how such a model can be implemented using the finite-difference time-domain method to model light propagation in general samples. The model employs vectorial focussing theory to represent the optical system and, thus, incorporates general illumination beam types and detection ...

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    4. University Hospitals names Marco A. Costa as vice president and chief

      University Hospitals names Marco A. Costa as vice president and chief

      University Hospitals means business when it comes to innovation — so much so that it has launched a new office dedicated to it. UH recently created the executive office of innovation and appointed Dr. Marco A. Costa as vice president and chief innovation officer of the health system. In the new role, Costa will lead a team focused on “initiatives related to innovation to maximize quality, patient experience and performance,” according to a news release. Costa most recently served as director of the Interventional Cardiovascular Center and director of the Research and Innovation Center at the UH Harrington Heart & Vascular Institute ...

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    5. Heidelberg Engineering launches new software upgrade

      Heidelberg Engineering launches new software upgrade

      Heidelberg Engineering has launched new software for its Spectralis 6.00 OCT (pictured). Key features of the new software include faster image acquisition and more intuitive analysis. The company believes that the free download reinforces the benefits of the technology being an upgradeable platform. The upgrade enables Spectralis users to gain more information from both new and previously taken scans, providing full segmentation of the retinal layers and longitudinal section analysis for a top down view. It comes with a comprehensive tutorial, highlighting the access to information on the integrity of specific layers. Heidelberg Engineering clinical programme manager, Christopher Mody ...

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    6. Research Associate/Research Fellow Optical Coherence Elastography at University of Western Australia

      Research Associate/Research Fellow Optical Coherence Elastography at University of Western Australia

      Job no: 493993 Work type: full-time Location: Crawley Categories: Engineering / Computing and Mathematics SCHOOL OF ELECTRICAL, ELECTRONIC & COMPUTER ENGINEERING OPTICAL+BIOMEDICAL ENGINEERING LABORATORY 2 year appointment, with the possibility of extension Salary range: Level A $63,332 - $85,942 p.a. or Level B $90,468 - $107,431 p.a. (dependent on qualifications and experience) Research & Development In Biomedical Photonics (Australia) The University of Western Australia (UWA) is a member of Australia's prestigious Group of Eight and ranked among the top 100 universities (88 th in the world) with a broad and balanced coverage of disciplines in the arts ...

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    7. Structural and functional changes in glaucoma: comparing the two-flash multifocal electroretinogram to optical coherence tomography and visual field

      Structural and functional changes in glaucoma: comparing the two-flash multifocal electroretinogram to optical coherence tomography and visual field

      Purpose To correlate multifocal electroretinogram (mfERG) findings in the macular area of glaucoma patients with automated perimetry (visual fields) and with optical coherence tomography (OCT). Methods A two-global flash mfERG (VERIS™) was recorded in 20 eyes with primary open-angle glaucoma. The root mean square was calculated, and three response epochs were analysed: the direct component (15–45 ms) and two induced components (IC-1 at 45–75 ms and IC-2 at 75–105 ms). The central 10° of the mfERG was compared to the central 10° of the OCT and of the visual field. Responses grouped in a superior and in ...

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    8. Optical coherence tomography vs intravascular ultrasound in the evaluation of observer variability and reliability in the assessment of stent deployment: The OCTIVUS Study

      Optical coherence tomography vs intravascular ultrasound in the evaluation of observer variability and reliability in the assessment of stent deployment: The OCTIVUS Study

      Abstract Objectives : To compare the variability in the assessment of coronary stents among interventional cardiologists (readers) using Optical Coherence Tomography (OCT) and Intravascular ultrasound (IVUS). Background : IVUS is established and validated in the evaluation of coronary stent. For cardiologists without core lab expertise, the utility of IVUS is limited by image quality. OCT yields higher image resolution, however, the consistency with which these readers interpret OCT images has not been fully evaluated or compared with IVUS. Methods : OCT and IVUS image sets (5 pairs) obtained following stent placement were reviewed by readers with clinical experience with both modalities. Parameters assessed ...

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    9. Impact of coronary artery stent edge dissections on long-term clinical outcome in patients with acute coronary syndrome: An Optical Coherence Tomography Study

      Impact of coronary artery stent edge dissections on long-term clinical outcome in patients with acute coronary syndrome: An Optical Coherence Tomography Study

      Aims: The purpose of the present study was to assess the incidence, predictors and long term prognosis of stent edge dissections identified by (OCT) after the implantation of bare metal (BMS) and drug eluting stents (DES). Methods and results: We studied 74 patients who underwent percutaneous coronary intervention (PCI) because of an acute coronary syndrome. Edge dissections were found in 29 of 74 patients (39.1%). Independent predictors of edge dissections were: the presence of ST-elevation myocardial infarction (STEMI) (p=0.005, odds ratio 11.78; 95% Cl 2.06-67.10), the small reference lumen diameter ( p= 0.009, odds ...

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    10. Choroidal Imaging with Swept Source Optical Coherence Tomography – A Review

      Choroidal Imaging with Swept Source Optical Coherence Tomography – A Review

      The choroid provides up to 70 % of blood and oxygen to the eye. Pathological changes of this vascular tissue may lead to malnutrition of the retina and therefore be involved in the pathogenesis of numerous retinal disorders. Swept source optical coherence tomography (SS-OCT) is a new development of a non-invasive imaging technique that uses a tunable laser source with a higher wavelength light than conventional spectral domain OCT (SD-OCT). This enables visualisation of tissues below the retinal pigment epithelium. Thanks to SS-OCT’s ultrahigh speed and ultrahigh resolution it is possible to assess choroidal layers as well as to automatically ...

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    11. Optical Coherence Tomography Identifies Lower Labial Salivary Gland Surface Density in Cystic Fibrosis

      Optical Coherence Tomography Identifies Lower Labial Salivary Gland Surface Density in Cystic Fibrosis

      The labial minor salivary glands (LSGs) are easily accessible mucus-secreting structures of the alimentary tract that may provide new information on the basis of gastrointestinal complications of cystic fibrosis (CF). It was shown that they are destructed in the course of cystic fibrosis. We employed wide-field, micrometer resolution in vivo optical coherence tomography to assess the surface density of LSGs in 18 patients with CF and 18 healthy subjects. The median LSGs’ surface densities in CF patients, and in the control group were 4.32 glands/cm2 and 6.58 glands/cm2, respectively (p = 0.006; Mann-Whitney U test). A ...

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    12. Optical Coherence Tomography Identifies Lower Labial Salivary Gland Surface Density in Cystic Fibrosis

      Optical Coherence Tomography Identifies Lower Labial Salivary Gland Surface Density in Cystic Fibrosis

      The labial minor salivary glands (LSGs) are easily accessible mucus-secreting structures of the alimentary tract that may provide new information on the basis of gastrointestinal complications of cystic fibrosis (CF). It was shown that they are destructed in the course of cystic fibrosis. We employed wide-field, micrometer resolution in vivo optical coherence tomography to assess the surface density of LSGs in 18 patients with CF and 18 healthy subjects. The median LSGs’ surface densities in CF patients, and in the control group were 4.32 glands/cm 2 and 6.58 glands/cm 2 , respectively (p = 0.006; Mann-Whitney U ...

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    13. Keysight PCIe data acquisition card has OCT capability

      Keysight PCIe data acquisition card has OCT capability

      Keysight Technologies has announced that the U5303A high-speed data acquisition 12-bit PCIe card, in collaboration with firmware firm YellowSys is available with an option dedicated to the optical coherence tomography (OCT) technology. The data acquisition card uses signal resampling to give stable ADC signal sampling with clock stability while acquiring the signal in order to avoid sampling cadence changes, which can occur when an external k-clock is used. The signal processing is done in real-time directly on the data acquisition card and not on the host PC. “OCT technology is evolving at a fast pace and we strongly believe in ...

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    14. Haag-Streit UK appointed sole distributor of the Optovue, Inc. portfolio in the UK

      Haag-Streit UK appointed sole distributor of the Optovue, Inc. portfolio in the UK

      Haag-Streit UK (HS-UK), the leading manufacturer and distributor of gold-standard optometry and ophthalmic equipment, is pleased to announce that it will be appointed sole distributor of the Optovue, Inc. product portfolio in the UK from 4th February 2015. Optovue, Inc, has a reputation for pushing the frontiers of innovation and ophthalmic medical diagnostic imaging with its Optical Coherence Tomography (OCT) product portfolio, which includes the: Angiovue OCT Angiography system, iVue, iFusion, iScan and XR Avanti OCT products. HS-UK will be taking over the UK distribution from Watford-based Grafton Optical, Optovue, Inc distributors since January 2007. Bill Shields, Vice President International ...

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    15. High resolution Fourier domain optical coherence tomography in the 2 um wavelength range using a broadband supercontinuum source

      High resolution Fourier domain optical coherence tomography in the 2 um wavelength range using a broadband supercontinuum source

      A 220 nm bandwidth supercontinuum source in the two-micron wavelength range has been developed for use in a Fourier domain optical coherence tomography (FDOCT) system. This long wavelength source serves to enhance probing depth in highly scattering material with low water content. We present results confirming improved penetration depth in high opacity paint samples while achieving the high axial resolution needed to resolve individual paint layers. This is the first FDOCT developed in the 2 μm wavelength regime that allows fast, efficient capturing of 3D image cubes at a high axial resolution of 13 μm in air (or 9 μm ...

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    16. The effect of coronary artery plaque composition, morphology and burden on Absorb bioresorbable vascular scaffold expansion and eccentricity — A detailed analysis with optical coherence tomography

      The effect of coronary artery plaque composition, morphology and burden on Absorb bioresorbable vascular scaffold expansion and eccentricity — A detailed analysis with optical coherence tomography

      Aims Suboptimal stent expansion correlates with adverse cardiac events. There is limited information regarding Absorb bioresorbable vascular scaffold (BVS) expansion characteristics. Optical coherence tomography (OCT) allows for high-resolution assessment of plaque morphology, composition and assessment of BVS expansion. This study evaluates coronary plaque composition, morphology and burden and their effect on Absorb BVS expansion using OCT. Methods and results Two thousand three hundred and thirty four frames totalling 462.6 mm of BVS from twenty OCT-guided BVS implantations were examined. 200 μm longitudinal cross-sections of each BVS were analysed for lumen contours and plaque characteristics. The relationship between each plaque ...

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    17. Photonics Media Seeks Presenters for Biophotonic Imaging Digital Conference

      Photonics Media Seeks Presenters for Biophotonic Imaging Digital Conference

      Researchers in the field of bioimaging around the world are invited to give presentations at a digital conference to be hosted by Photonics Media this summer. “Biophotonic Imaging for Medicine” will focus on a range of light-based imaging and microscopy techniques for diagnosing and assessing illness, or studying other attributes and functions of biological tissue in a biomedical context. It will take place from 1 to 5 p.m. EST on Thursday, June 11. Click here to submit an abstract. Like Photonics Media’s popular series of webinars, the conference will be presented free via the Web to a knowledgeable ...

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    18. Feature Of The Week 01/25/15: Detection and characterisation of biopsy tissue using quantitative optical coherence elastogaphy (OCE) in men with suspected prostate cancer.

      Feature Of The Week 01/25/15: Detection and characterisation of biopsy tissue using quantitative optical coherence elastogaphy (OCE) in men with suspected prostate cancer.

      Prostate cancer (PCa) is the most common non-cutaneous malignancy in men. Men suspected with PCa are then offered transrectal ultrasound (TRUS) guided prostate biopsies to confirm the diagnosis, which falls short of making a reliable differentiation between cancer and benign hyperplasia of the gland. Suspected cancerous lesions tend to be stiffer (or harder to feel) than benign tissue. Various elastography modalities such as Ultrasound elastography and MRI elastography are known to have poor spatial resolution, which limits their ability to differentiate small lesions and in identifying early and subtle changes. OCT is an optical imaging technique that enables high-resolution, cross-sectional ...

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    19. Side Branch Occlusion After Bioresorbable Vascular Scaffold Implantation Lessons From Optimal Coherence Tomography

      Side Branch Occlusion After Bioresorbable Vascular Scaffold Implantation Lessons From Optimal Coherence Tomography

      There are limited data regarding the side branch occlusion (SBO) after Absorb bioresorbable everolimus-eluting vascular scaffolds (BVS) 1.1 (Abbott Vascular, Santa Clara, California). Even though the second-generation BVS 1.1 has improved on the design of BVS 1.0, the increased strut thickness and width remain and potentially more frequently compromise small SB as compared to the new-generation drug-eluting stents with thin strut. A previous study 1 demonstrated that BVS had a higher incidence (10.5%) of post-procedural SBO compared with the everolimus-eluting metallic stent for SB with a reference vessel diameter ≤0.5 mm. Regarding SB with a ...

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    20. Utility Of Optical Coherence Tomography In The Evaluation Of Patients With Ethambutol-Induced Optic Neuropathy

      Utility Of Optical Coherence Tomography In The Evaluation Of Patients With Ethambutol-Induced Optic Neuropathy

      In this study, optical coherence tomography (OCT) was used to evaluate retinal thickness in two patients with optic neuropathy who had recently discontinued ethambutol. OCT was used to measure retinal nerve fiber layer (RNFL) thickness and to map the RNFL, ganglion cell layer (GCL), and inner plexiform layer (IPL). Decreased RNFL thickness was observed in one case. However, the combined RNFL, GCL, and IPL map showed significant decreases in retinal thickness in both cases, suggesting that ethambutol likely affects the GCL as well as the RNFL. I propose that the GCL thickness should be considered in addition to the RNFL ...

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      Mentions: Nidek Nidek RS-3000
    21. Calcified Nodule Mimicking Red Thrombus on Optical Coherence Tomography

      Calcified Nodule Mimicking Red Thrombus on Optical Coherence Tomography

      The single case report by Hao et al. 1 describing the unique pathological microstructure of a calcified nodule (CN) in an 89-year-old woman dying of congestive heart failure provides unique clues to advance our ability to interpret the images provided by intracoronary diagnostic techniques. The beauty of this report is that a detailed pathological analysis of the CN was combined with corresponding intravascular ultrasound (IVUS), optical coherence tomography (OCT), and coronary angioscopy findings. Of note, this CN was not complicated because it was completely covered by a continuous endothelial layer and had no trace of any residual superficial thrombus. Interestingly ...

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    22. OCT measurements of optic nerve head changes in idiopathic intracranial hypertension

      OCT measurements of optic nerve head changes in idiopathic intracranial hypertension

      Objective Severity of papilledema and vision loss constitute a basis for therapeutic intervention in idiopathic intracranial hypertension (IIH), but both are often subjective and insensitive in guiding clinical management. The aim of this study was to identify reliable and sensitive measurements of optic nerve head (ONH) and macula, to provide objective guidance for prognostic evaluation and treatment in IIH. We analyzed potential of spectral domain optical coherence tomography (SD-OCT), to measure neuro-retinal rim thickness and area, optic cup-to-disc ratio (C/D) and cup volume of ONH which have not previously been reported in IIH. In parallel, thickness of peripapillary retinal ...

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    1-24 of 16029 1 2 3 4 ... 666 667 668 »
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