1. Featured Articles

    1. Research Associate / Postdoctoral Fellow in Adaptive Optics and Optical Coherence Tomography at Indiana University

      Explore Optical Coherence Tomography News Ophthalmology , Jobs & Studentships
      Research Associate / Postdoctoral Fellow in Adaptive Optics and Optical Coherence Tomography at Indiana University

      The Advanced Ophthalmic Imaging Laboratory at Indiana University is looking to fill a postdoctoral fellow or research associateposition. The successful candidate will join a team of scientists and engineers that are developing adaptive optics–optical coherence tomography (AO-OCT) for studying structure and function of the living human retina at the cellular level. The system is opening exciting new directions to study both normal and pathological vision. The laboratory ( www.opt.indiana.edu/dtmiller/Index.aspx ) is part of an active and well-funded community of vision scientists and engineers working in the areas of visual optics, retinal imaging, OCT, and adaptive ...

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      Mentions: Donald T. Miller Indiana University

    2. Development of a clinical prototype of a miniature hand-held optical coherence tomography probe for prematurity and pediatric ophthalmic imaging

      Explore OSA | OSA Publishing Ophthalmology , Probes
      Development of a clinical prototype of a miniature hand-held optical coherence tomography probe for prematurity and pediatric ophthalmic imaging

      We report a novel design and operation of a highly integrated miniature handheld OCT probe, with high-speed angiography function that can be used in clinical settings for young children and infants, providing rapid, non-invasive structural and angiographic imaging of the retina and choroid. The imaging system is operated at 200 kHz, with 3D OCT and OCTA scan time of 0.8 and 3.2 seconds, respectively, and the scanning angle on the pupil is ± 36°, covering the full perifoveal region. Operator assisting features of the direct-view iris camera and on-probe display are integrated into the hand-held probe, and the fixation ...

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      Mentions: University of Washington Ruikang K. Wang University of Dundee

    3. Retinal single-layer analysis with optical coherence tomography (OCT) in schizophrenia spectrum disorder

      Explore ScienceDirect Ophthalmology
      Retinal single-layer analysis with optical coherence tomography (OCT) in schizophrenia spectrum disorder

      Background Volume reductions in brain structures of patients with schizophrenia spectrum disorder (SSD) have repeatedly been found in voxel-based morphometry MRI studies. Hence, an underlying neurodegenerative etiological component of SSD is currently being discussed. In recent years, the imaging method of optical coherence tomography (OCT) has shown its potential in evaluating structural changes in the retina in patients with confirmed neurodegenerative disorders, providing a window into the brain. Methods Twenty-six patients with schizophrenia or schizoaffective disorder and 23 age- and sex-matched healthy controls were examined with the Heidelberg Spectralis OCT system to derive a single-layer analysis of both retinas. The ...

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      Mentions: Heidelberg Spectralis

    4. Avinger Announces Publication of Study Demonstrating Positive Clinical Outcomes for Patients Treated with Pantheris Prior to Antirestenotic Therapy

      Explore Optical Coherence Tomography News Cardiology
      Avinger Announces Publication of Study Demonstrating Positive Clinical Outcomes for Patients Treated with Pantheris Prior to Antirestenotic Therapy

      Avinger, Inc. (NASDAQ: AVGR ), a leading developer of image-guided, catheter-based systems for the diagnosis and treatment of patients with Peripheral Artery Disease (PAD), today announced the publication of very promising clinical outcomes data from a study evaluating the performance of the Pantheris® Lumivascular atherectomy system combined with antirestenotic therapy in the treatment of PAD. This retrospective single-center, single-arm study has been published in the April 2019 issue of the peer-reviewed Journal of Cardiovascular Surgery under the title "Optical Coherence Tomography Guided Directional Atherectomy with Antirestenotic Therapy for Femoropopliteal Arterial Disease." The study analyzed the clinical outcomes of 33 patients (37 ...

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      Mentions: Avinger Arne G. Schwindt

    5. Optical computing optical coherence tomography with conjugate suppression by dispersion

      Explore OSA | OSA Publishing Other Non-Medical
      Optical computing optical coherence tomography with conjugate suppression by dispersion

      For all imaging techniques, such as optical coherence tomography (OCT), fast imaging speed is always of high demand. Optical computing OCT ( OC2T) has achieved ultrahigh speed for real time 3D imaging without post data processing, but its spatial resolution is lowered down due to an imperfect Fourier transformation in the optical computing process. In this Letter, we illustrate the theory of OC2T and prove that the dispersion imbalance between reference arm and sample arm may be introduced to improve the resolution. Furthermore, this novel OC2T technique can also enable a conjugate restrained OCT imaging without any data processing, achieving ∼ 2 ...

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      Mentions: Tsinghua University Ping Xue Chengming Wang

    6. Effect of solvent lamination on roll-to-roll hot-embossed PMMA microchannels evaluated by optical coherence tomography

      Explore IOPscience NDE/NDT
      Effect of solvent lamination on roll-to-roll hot-embossed PMMA microchannels evaluated by optical coherence tomography

      Manufacturing of microfluidic based diagnostic devices requires small tolerances and uniform quality to guarantee reliable and repeatable test results. This work describes characterization of morphological changes that occur to a hot embossed PMMA microfluidic channel after solvent lamination with a PMMA lid. A non-contact cross-sectional analysis of the lidded microfluidic device was performed by optical coherence tomography (OCT). The solvent induced morphology change led to a porous structure in bottom corners of hot-embossed channels, which allowed a fluid to absorb in the material. The measurements of solvent diffusion showed faster diffusion rate at the corners of the channel, in which ...

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      Mentions: Janne Lauri Tapio E. J. Fabritius University of Oulu

    7. Spatiotemporal optical coherence (STOC) manipulation suppresses coherent cross-talk in full-field swept-source optical coherence tomography

      Explore OSA | OSA Publishing
      Spatiotemporal optical coherence (STOC) manipulation suppresses coherent cross-talk in full-field swept-source optical coherence tomography

      Full-field swept-source optical coherence tomography (FF-SS-OCT) provides high-resolution depth-resolved images of the sample by parallel Fourier-domain interferometric detection. Although FF-SS-OCT implements high-speed volumetric imaging, it suffers from the cross-talk-generated noise from spatially coherent lasers. This noise reduces the transversal image resolution, which in turn, limits the wide adaptation of FF-SS-OCT for practical and clinical applications. Here, we introduce the novel spatiotemporal optical coherence (STOC) manipulation. In STOC the time-varying inhomogeneous phase masks are used to modulate the light incident on the sample. By properly adjusting these phase masks, the spatial coherence can be reduced. Consequently, the cross-talk-generated noise is suppressed ...

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      Mentions: Maciej Wojtkowski Nicolaus Copernicus University

    8. Novel approach for weld depth determination using optical coherence tomography measurement in laser deep penetration welding of aluminum and steel

      Explore Journal of Laser Applications NDE/NDT
      Novel approach for weld depth determination using optical coherence tomography measurement in laser deep penetration welding of aluminum and steel

      The optical coherence tomography (OCT) is a measuring technology which is well-established in medical engineering since the early 1990s. More recently, the technology found its way into laser materials processing where it is used for seam tracking and inspection and also for monitoring and control of deep-penetration laser welding. In this work, deep-penetration laser welding of aluminum and steel using an OCT-system for in-process monitoring of the weld depth was investigated. It is shown that statistical data processing is mandatory to extract the actual keyhole depth. Therefore, two different measures, percentile filtering and considering the frequency distribution of the OCT-data ...

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    9. Post-doctoral Adaptive Optics Research Fellow at U.S. Food and Drug Administration

      Explore Optical Coherence Tomography News Jobs & Studentships
      Post-doctoral Adaptive Optics Research Fellow at U.S. Food and Drug Administration

      Seeking a highly motivated post-doctoral Adaptive Optics Research Fellow to work at the U.S. Food and Drug Administration, Center for Devices and Radiological Health. The candidate will work in the Division of Biomedical Physics under the direction of Drs. Zhuolin Liu and Daniel X. Hammer and perform research with the FDA multimodal adaptive optics (mAO) imager. The FDA mAO imaging system allows visualization of different retinal cells, including ganglion cells, retinal pigment epithelial cells, and photoreceptors. The candidate will be expected to: conduct human imaging in healthy and diseased eyes, perform data processing, analysis and presentation, develop new and ...

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      Mentions: University of Maryland Daniel X. Hammer FDA

    10. New England College of Optometry Professor Releases OCT Visual Atlas app – OCTaVIA

      Explore New England College of Optometry Ophthalmology
      New England College of Optometry Professor Releases OCT Visual Atlas app – OCTaVIA

      OCTaVIA, a visual reference OCT app, is now available free to eye care professionals and optometry/ophthalmology students of all levels on the Apple App Store. The iOS Optical Coherence Tomography (OCT) app was developed by Dr. Elena Z Biffi, Assistant Professor, New England College of Optometry (NECO) and attending optometrist at South Boston Community Health Center to assist in the diagnosis and management of retinal disorders in their daily practice. Dr. Biffi notes, “There is an urgent need in education and clinical practice for a dedicated smartphone/tablet app that can present a well-annotated OCT images for multiple diseases ...

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    11. PhD Studentship in Biomedical Optics and Retinal Imaging at The University of Illinois at Chicago

      Explore Optical Coherence Tomography News Ophthalmology , Jobs & Studentships
      PhD Studentship in Biomedical Optics and Retinal Imaging at The University of Illinois at Chicago

      A PhD position is available in the Biomedical Optics and Functional Imaging group within the Department of Bioengineering, University of Illinois at Chicago. Our research lab is working on ultra-wide field fundus photography, functional optical coherence tomography (OCT), OCT angiography (OCTA), super-resolution ophthalmoscopy, retinal image analysis and classification ( https://yaolab.bioe.uic.edu/ ). The PhD student will be involved for imaging instrument development and/or experimental study of retinal morphology & physiology. The specific study plan of the student can be flexible based on his/her education background and interest. The successful candidate should have a BS/MS degree in Optical ...

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      Mentions: Xincheng Yao
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  2. Recent Articles From Around The Web

    1. Boston Medical Center Receives NIH Grant for Eye To Brain: Eye Biomarkers and Cognition

      Explore Optical Coherence Tomography News Neurology , Ophthalmology , Funding
      Boston Medical Center Receives NIH Grant for Eye To Brain: Eye Biomarkers and Cognition

      Boston Medical Center Receives a 2019 NIH Grant for $197,189 for Eye To Brain: Eye Biomarkers and Cognition. The principal investigator is Manju Subramanian. The program began in 2019 and ends in 2021. Below is a summary of the proposed work. The goal of our research is to identify ocular biomarkers that have diagnostic and potentially prognostic utility in Alzheimer's Disease (AD), and establish a relationship to cognition. We seek to determine this relationship in an already established cohort of patients (the Vitreous Biomarkers Study, or VBS) with eye disease where protein biomarkers have been identified in the ...

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      Mentions: National Institutes of Health Boston University

    2. Best Clinical Practice for Age-Related Macular Degeneration Imaging

      Explore SAGE Journals Ophthalmology
      Best Clinical Practice for Age-Related Macular Degeneration Imaging

      Purpose: To identify best clinical practices for macular degeneration imaging. Methods: We reviewed best clinical practices for imaging patients with age-related macular degeneration. These recommendations are based on different levels of evidence (I-III). Results: The type of imaging needed depends to some degree on the clinical scenario: first visit vs follow-up visit vs poorly responsive patient. Conclusions: Imaging technologies that may be useful include optical coherence tomography, fundus photography, fundus autofluorescence imaging, fluorescein angiography, indocyanine green angiography, and optical coherence tomography angiography.

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      Mentions: Duke University Cynthia A. Toth K. Bailey Freund

    3. Optical Coherence Tomography Angiography Findings in Fabry Disease

      Explore MDPI Open Access Journals Platform Ophthalmology
      Optical Coherence Tomography Angiography Findings in Fabry Disease

      Background: Fabry disease (FD) is a X-linked recessive lysosomal storage disorder characterized by altered biodegradation of glycosphingolipids. It is a multisystem pathology, also involving ophthalmological systems that show modifications of the vessel wall due to glycosphingolipid deposits. Optical coherence tomography angiography (OCT-A) allows for an objective analysis of retinal microvasculature alterations, evaluating retinal vessel density in macular region. Methods: A total of 54 FD patients (34 females, 20 males, mean age 44.1 ± 15.6 years) and 70 controls (36 females, 34 males, mean age 42.3 ± 15.6 years) were included in this study. We evaluated vessel density in ...

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      Mentions: University Federico II

    4. Appearance of Polypoidal Lesions in Patients With Polypoidal Choroidal Vasculopathy Using Swept-Source Optical Coherence Tomographic Angiography

      Explore The JAMA Network Ophthalmology
      Appearance of Polypoidal Lesions in Patients With Polypoidal Choroidal Vasculopathy Using Swept-Source Optical Coherence Tomographic Angiography

      Importance Polypoidal choroidal vasculopathy (PCV) is a major cause of visual loss worldwide, particularly in Asia, and the appropriate understanding of the structures in PCV previously described as polypoidal lesions is important for understanding their pathogenesis, diagnosis, and prognosis. Objective To report the morphologic characteristics of polypoidal lesions and their association with branching vascular networks (BVNs) in eyes with PCV using swept-source optical coherence tomographic angiography (SS-OCTA). Design, Setting, and Participants This cross-sectional observational study included 20 participants recruited from Shanghai General Hospital with a diagnosis of PCV based on the presence of focal hyperfluorescent spots on indocyanine green angiography ...

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      Mentions: Philip J. Rosenfeld University of Miami Shanghai Jiao Tong University

    5. Measurement of Vessel Density Using Optical Coherence Tomography-angiography in Normal Subjects: Difference by Analysis Area

      Explore KoreaMed Synapse Ophthalmology
      Measurement of Vessel Density Using Optical Coherence Tomography-angiography in Normal Subjects: Difference by Analysis Area

      Purpose To evaluate the vessel density of macula according to analysis area in health subjects using optical coherence tomography angiography (OCTA). Methods We retrospectively analyzed 30 eyes of 20 healthy people who underwent OCTA. We measured vessel density (VD) according to analysis area and foveal avascular zone (FAZ) size of superficial capillary plexus (SCP) and deep capillary plexus (DCP). The analysis areas were classified as 3 × 3 mm scan area (Box), Box area excluding FAZ (Box-FAZ), fovea centered 3 mm circle area (Circle), Circle area excluding FAZ (Circle-FAZ) and area between fovea centered 1 mm circle and 3 mm circle ...

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      Mentions: Sungkyunkwan University

    6. Microvascular changes in amblyopic eyes detected by optical coherence tomography angiography

      Explore Journal of AAPOS Ophthalmology
      Microvascular changes in amblyopic eyes detected by optical coherence tomography angiography

      Purpose To investigate retinal microvascular findings detected by optical coherence tomography angiography (OCT-A) in amblyopic eyes compared with normal eyes. Methods A total of 23 amblyopic (strabismic, ametropic, anisometropic, and meridional amblyopia) and 22 normal eyes were included in this prospective observational, comparative study. All patients underwent complete ophthalmological examination and OCT-A imaging. Vessel density (VD) percentage in the superficial and deep retinal vessel plexus, foveal avascular zone (FAZ) area, flow area in the outer retina and choriocapillaris, and retinal thickness in μm in a 6.00 × 6.00 mm scan size were measured and compared between groups. Results There ...

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    7. Collateral Vessels in Branch Retinal Vein Occlusion: Anatomic and Functional Analyses by Optical Coherence Tomography Angiography

      Explore ScienceDirect Ophthalmology
      Collateral Vessels in Branch Retinal Vein Occlusion: Anatomic and Functional Analyses by Optical Coherence Tomography Angiography

      Purpose To anatomically and functionally analyze collateral vessels (CVs) associated with branch retinal vein occlusion (BRVO) using optical coherence tomography angiography (OCTA). Design Retrospective review Participants Twenty-nine consecutive cases with BRVO. Methods The distribution of the CVs 12 months after the onset of BRVO was studied using spectral-domain OCTA. En-face 3×3-mm OCTA images were acquired from nine locations centered on the fovea and used to create a montage image of an 8.1 × 8.1-mm square. The CVs were identified in three separate areas: the radial peripapillary capillary (RPC), superficial capillary plexus (SCP), and deep capillary plexus (DCP) layers ...

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    8. Restenosis of a Polytetrafluoroethylene-Covered Stent Visualized by Coronary Angioscopy and Optical Coherence Tomography: A Case Report

      Explore Thieme Cardiology
      Restenosis of a Polytetrafluoroethylene-Covered Stent Visualized by Coronary Angioscopy and Optical Coherence Tomography: A Case Report

      An expandable polytetrafluoroethylene (PTFE)-covered stent graft is beneficial for the treatment of coronary perforations. However, several reports have shown that restenosis and thrombotic occlusion occasionally occur in the stented segment after PTFE-covered stent implantation. A restenosis case after treatment with PTFE-covered stent against saphenous vein graft (SVG) perforation has never been evaluated with optical coherence tomography (OCT) or coronary angioscopy (CAS). This case report presents a 75-year-old man treated with a PTFE-covered stent after he suffered from SVG perforation 6 months ago. He was found to have a focal restenosis of the distal edge of the PTFE-covered stent and ...

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      Mentions: Keiichi Hishikari

    9. Influence of Axial Length on Parafoveal and Peripapillary Metrics from Swept Source Optical Coherence Tomography Angiography.

      Explore Taylor & Francis Online Ophthalmology
      Influence of Axial Length on Parafoveal and Peripapillary Metrics from Swept Source Optical Coherence Tomography Angiography.

      Purpose : To assess the effect of axial length (AL) on the quantification of superficial vessel density of both macular and disc region using swept source optical coherence tomography angiography (SSOCTA). Methods : This is a cross-sectional clinical study. Seventy-five eyes from 75 Chinese healthy participants (56 females) with a mean age of 26.6±6.8 (range 19-50) years were included in this study. All eyes were imaged with SSOCTA, using a 3×3mm scan pattern centered on the macular and optic disc respectively, and the superficial layer was used for evaluation. The image size was corrected with AL using Bennett ...

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      Mentions: Shanghai Jiao Tong University

    10. 2D MEMS-based high-speed beam-shifting technique for speckle noise reduction and flow rate measurement in optical coherence tomography

      Explore OSA | OSA Publishing
      2D MEMS-based high-speed beam-shifting technique for speckle noise reduction and flow rate measurement in optical coherence tomography

      In this manuscript, a two-dimensional (2D) micro-electro-mechanical system (MEMS)-based, high-speed beam-shifting spectral domain optical coherence tomography (MHB-SDOCT) is proposed for speckle noise reduction and absolute flow rate measurement. By combining a zigzag scanning protocol, the frame rates of 45.2 Hz for speckle reduction and 25.6 Hz for flow rate measurement are achieved for in-vivo tissue imaging. Phantom experimental results have shown that by setting the incident beam angle to ϕ = 4.76° (between optical axis of objective lens and beam axis) and rotating the beam about the optical axis in 17 discrete angular positions, 91% of speckle ...

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      Mentions: University of Toronto Sunnybrook Health Sciences Centre Victor X. D. Yang

    11. The effect of panretinal photocoagulation (PRP) versus intravitreal bevacizumab (IVB) plus prp on peripapillary retinal nerve fiber layer (RNFL) thickness analyzed by optical coherence tomography in patients with proliferative diabetic retinopathy

      Explore jovr.org Ophthalmology
      The effect of panretinal photocoagulation (PRP) versus intravitreal bevacizumab (IVB) plus prp on peripapillary retinal nerve fiber layer (RNFL) thickness analyzed by optical coherence tomography in patients with proliferative diabetic retinopathy

      Purpose: The current study aimed to evaluate changes in peripapillary retinal nerve fiber layer (RNFL) thickness in diabetic patients with bilateral proliferative diabetic retinopathy (PDR) after receiving panretinal photocoagulation (PRP) or intravitreal bevacizumab (IVB) with PRP. Methods: Ocular examination and peripapillary optical coherent tomography (OCT) were performed for each patient at baseline, 1, 3, 6, and 10 months after treatment. Both eyes of each patient were randomized into either PRP or PRP + IVB group. Results: Sixty-four eyes (32 patients) were enrolled in this randomized clinical trial. In the PRP group, global RNFL thickness initially increased and reached statistical significance in ...

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      Mentions: Harvard University Massachusetts Eye and Ear Infirmary

    12. Simultaneous denoising and super-resolution of optical coherence tomography images based on generative adversarial network

      Explore OSA | OSA Publishing
      Simultaneous denoising and super-resolution of optical coherence tomography images based on generative adversarial network

      Optical coherence tomography (OCT) has become a very promising diagnostic method in clinical practice, especially for ophthalmic diseases. However, speckle noise and low sampling rates have intensively reduced the quality of OCT images, which prevents the development of OCT-assisted diagnosis. Therefore, we propose a generative adversarial network-based approach (named SDSR-OCT) to simultaneously denoise and super-resolve OCT images. Moreover, we trained three different super-resolution models with different upscale factors (2× , 4× and 8×) to adapt to the corresponding downsampling rates. We also quantitatively and qualitatively compared our proposed method with some well-known algorithms. The experimental results show that our approach can ...

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    13. Treatment of In-Stent Restenosis by Excimer Laser Coronary Atherectomy and Drug-Coated Balloon: Serial Assessment with Optical Coherence Tomography

      Explore Hindawi Publishing Corporation Cardiology
      Treatment of In-Stent Restenosis by Excimer Laser Coronary Atherectomy and Drug-Coated Balloon: Serial Assessment with Optical Coherence Tomography

      Objectives . We aimed to compare the results of neointimal modification before drug-coated balloon (DCB) treatment with excimer laser coronary atherectomy (ELCA) plus scoring balloon predilation versus scoring balloon alone in patients presenting with in-stent restenosis (ISR). Background . Treatment of ISR with ELCA typically results in superior acute gain by neointima debulking. However, the efficacy of combination therapy of ELCA and DCB remains unknown. Methods . A total of 42 patients (44 ISR lesions) undergoing DCB treatment with ELCA plus scoring balloon (ELCA group, n = 18) or scoring balloon alone (non-ELCA group, n = 24) were evaluated via serial assessment by optical coherence ...

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      Mentions: Tokyo Medical & Dental University

    14. Line-Field Optical Coherence Tomography as a tool for In vitro characterization of corneal biomechanics under physiological pressures

      Explore Nature Publishing Group Ophthalmology
      Line-Field Optical Coherence Tomography as a tool for In vitro characterization of corneal biomechanics under physiological pressures

      There has been a lot of interest in accurately characterising corneal biomechanical properties under intraocular pressure (IOP) to help better understand ocular pathologies that are associated with elevated IOP. This study investigates the novel use of Line-Field Optical Coherence Tomography (LF-OCT) as an elastographic tool for accurately measuring mechanical properties of porcine corneas based on volumetric deformation following varying IOPs. A custom-built LF-OCT was used to measure geometrical and corneal surface displacement changes in porcine corneas under a range of IOPs, from 0–60 mmHg. Corneal thickness, elastic properties and hysteresis were calculated as a function of pressure. In addition ...

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      Mentions: Yalin Zheng

    15. Long-range common-path spectral domain optical coherence tomography

      Explore OSA | OSA Publishing Probes
      Long-range common-path spectral domain optical coherence tomography

      Fiber-based common-path spectral domain optical coherence tomography (SD-OCT) is compact and polarization insensitive, which is usually used in endoscopic biomedical imaging. In this study, we investigate a method to extend the working distance of a common-path SD-OCT system. Common-path OCT light, which consisting of sample and reference light signal, is directed into a free space optical interferometer. The OCT light is split spatially into two beam segments by a wavefront-splitting mirror, and the two parallel beams interfere noncollinearly in the interferometer. Distance between the end of the probing fiber, which serves as the reference plane of our OCT system, and ...

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      Mentions: Yimin Wang Xiangyang Zhang
      16. See all articles
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    Research Associate / Postdoctoral Fellow in Adaptive Optics and Optical Coherence Tomography at Indiana University Development of a clinical prototype of a miniature hand-held optical coherence tomography probe for prematurity and pediatric ophthalmic imaging Retinal single-layer analysis with optical coherence tomography (OCT) in schizophrenia spectrum disorder Avinger Announces Publication of Study Demonstrating Positive Clinical Outcomes for Patients Treated with Pantheris Prior to Antirestenotic Therapy Optical computing optical coherence tomography with conjugate suppression by dispersion Effect of solvent lamination on roll-to-roll hot-embossed PMMA microchannels evaluated by optical coherence tomography Spatiotemporal optical coherence (STOC) manipulation suppresses coherent cross-talk in full-field swept-source optical coherence tomography Novel approach for weld depth determination using optical coherence tomography measurement in laser deep penetration welding of aluminum and steel Post-doctoral Adaptive Optics Research Fellow at U.S. Food and Drug Administration New England College of Optometry Professor Releases OCT Visual Atlas app – OCTaVIA PhD Studentship in Biomedical Optics and Retinal Imaging at The University of Illinois at Chicago Boston Medical Center Receives NIH Grant for Eye To Brain: Eye Biomarkers and Cognition

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    1. We can’t use functional OCT/OCTA in the brain to look at neurovascular coupling at the cellular level because the brain is surrounded by the skull, and fine resolution isn’t possible...But we can use functional OCT/OCTA to examine the interactions between individual photoreceptors and their blood vessels in the retina, which is much more accessible in the eye.
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    2. With the NSTIN plot, the temporal quadrant of the retinal nerve fiber layer is displayed in the center of the B-scan. This portion of the disc is crucial for everyday visual function, and identification of abnormal thinning in this region is essential for managing glaucoma.
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    6. You can see right into the tooth,” said Dr. Daniel Fried, professor, University of California, San Francisco School of Dentistry. “The enamel looks almost like an ice cube...Many lesions in the mouth have been re-mineralized and...no longer need inter­vention,” said Fried. “Dentists have trouble telling the difference between active and arrested lesions; this new technology has the potential of differentiating them.
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    8. This is the largest meeting in the world for biomedical optics, and that's because of you!
      By Rox Anderson
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