1. Featured Articles

    1. HP-OCT™ wins Victorian AEEA award – nominated for Sir William Hudson award

      Explore Optical Coherence Tomography News Ophthalmology , Other Business News
      HP-OCT™ wins Victorian AEEA award – nominated for Sir William Hudson award

      Cylite Pty Ltd, a developer and manufacturer of 4 th Generation OCT systems for Ophthalmology and Optometry, is thrilled to announce it has won the Australian Engineering Excellence Award Victoria. The Australian Engineering Excellent Awards first began in 1988, after a decade of celebrating local projects through an Engineers Australia office. Brought to the national stage, an excellence award recognises outstanding achievement in engineering and the invaluable contribution that engineering makes to the economy, community and environment. Winning projects exhibit excellence, distinction, merit, perfection and quality. Kylee Hall, Cylite’s VP Sales and Marketing Manager commented, ”It is such an ...

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      Mentions: Cylite

    2. Postdoctoral Scholar in High Resolution Retinal Imaging at The Ohio State University

      Explore Optical Coherence Tomography News Ophthalmology , Jobs & Studentships
      Postdoctoral Scholar in High Resolution Retinal Imaging at The Ohio State University

      A NIH funded Post Doctoral Scholar position is available in the laboratory of Drs. Nathan Doble and Stacey Choi in the College of Optometry/Department of Ophthalmology and Visual Science at The Ohio State University (OSU). The successful candidate will work within a highly collaborative research environment focused on the development and use of novel high-resolution optical instrumentation for the study of retinal structure and function. The candidate will be expected to assist with construction and validation of novel instrumentation as well as the collection and analysis of the experimental data; preparation of research results for publication and talks; writing ...

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      Mentions: National Institutes of Health UC Davis The Ohio State University

    3. Semi-automated registration and segmentation for gingival tissue volume measurement on 3D OCT images

      Explore OSA | OSA Publishing
      Semi-automated registration and segmentation for gingival tissue volume measurement on 3D OCT images

      The change in gingival tissue volume may be used to indicate changes in gingival inflammation, which may be useful for the clinical assessment of gingival health. Properly quantifying gingival tissue volume requires a robust technique for accurate registration and segmentation of longitudinally captured 3-dimensional (3D) images. In this paper, a semi-automated registration and segmentation method for micrometer resolution measurement of gingival-tissue volume is proposed for 3D optical coherence tomography (OCT) imaging. For quantification, relative changes in gingiva tissue volume are measured based on changes in the gingiva surface height using the tooth surface as a reference. This report conducted repeatability ...

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      Mentions: University of Washington Ruikang K. Wang Steven L. Jacques

    4. Pet laser pointers have enough power to “blast away” cells in the back of the eye

      Explore Ohio State News Ophthalmology
      Pet laser pointers have enough power to “blast away” cells in the back of the eye

      Laser pointers used to exercise pets may seem like safe and simple low-powered devices, but an Ohio teen learned the hard way that staring at the narrow beam can cause permanent eye damage. His minimal vision loss tells some of the story, but a high-resolution optical imaging device developed by Ohio State University researchers showed in stark detail that cells in the boy’s retinas are missing – “blasted away” by the laser, his ophthalmologist explained. This area of the eye is home to photoreceptors, light-sensitive cells (often referred to as rods and cones) that allow us to “see.” These cells ...

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      Mentions: The Ohio State University

    5. Influence of tissue fixation on depth-resolved birefringence of oral cavity tissue samples

      Explore SPIE Digital Library Dentistry
      Influence of tissue fixation on depth-resolved birefringence of oral cavity tissue samples

      Significance: To advance our understanding of the contrast observed when imaging with polarization-sensitive optical coherence tomography (PS-OCT) and its correlation with oral cancerous pathologies, a detailed comparison with histology provided via ex vivo fixed tissue is required. The effects of tissue fixation, however, on such polarization-based contrast have not yet been investigated. Aim: A study was performed to assess the impact of tissue fixation on depth-resolved (i.e., local) birefringence measured with PS-OCT. Approach: A PS-OCT system based on depth-encoded polarization multiplexing and polarization-diverse detection was used to measure the Jones matrix of a sample. A wide variety of ex ...

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      Mentions: Massachusetts General Hospital Harvard University David D. Sampson

    6. Industrialization Potential of Optics in Biomedicine (On-Line Conference October 7 & 8, 2020)

      Explore i-pob.edu.pl
      Industrialization Potential of Optics in Biomedicine (On-Line Conference October 7 & 8, 2020)

      The conference will be focused on the past, current and the future developments of optical biomedical imaging techniques. The program of the i-POB conference will provide companies with an opportunity to share the experience and tribulations of taking a new discovery to the market with researchers that are successful in the process of implementing new technologies. The event will include opportunities for interaction between, scientist, innovators and entrepreneurs, including education on how to successfully run projects, start the company and enter to the global market. The meeting will be especially instructive for junior researchers and inventors interested in the development ...

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    7. Correlative infrared optical coherence tomography and hyperspectral chemical imaging

      Explore OSA | OSA Publishing NDE/NDT
      Correlative infrared optical coherence tomography and hyperspectral chemical imaging

      Optical coherence tomography (OCT) is a high-resolution three-dimensional imaging technique that enables nondestructive measurements of surface and subsurface microstructures. Recent developments of OCT operating in the mid-infrared (MIR) range (around 4 µm) lifted fundamental scattering limitations and initiated applied material research in formerly inaccessible fields. The MIR spectral region, however, is also of great interest for spectroscopy and hyperspectral imaging, which allow highly selective and sensitive chemical studies of materials. In this contribution, we introduce an OCT system (dual-band, central wavelengths of 2 µm and 4 µm) combined with MIR spectroscopy that is implemented as a raster scanning chemical imaging ...

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      Mentions: Bettina Heise RECENDT

    8. The optoretinogram reveals the primary steps of phototransduction in the living human eye

      Explore Science Advances Ophthalmology
      The optoretinogram reveals the primary steps of phototransduction in the living human eye

      Photoreceptors initiate vision by converting photons to electrical activity. The onset of the phototransduction cascade is marked by the isomerization of photopigments upon light capture. We revealed that the onset of phototransduction is accompanied by a rapid (<5 ms), nanometer-scale electromechanical deformation in individual human cone photoreceptors. Characterizing this biophysical phenomenon associated with phototransduction in vivo was enabled by high-speed phase-resolved optical coherence tomography in a line-field configuration that allowed sufficient spatiotemporal resolution to visualize the nanometer/millisecond-scale light-induced shape change in photoreceptors. The deformation was explained as the optical manifestation of electrical activity, caused due to rapid charge displacement ...

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      Mentions: B. Hyle Park Stanford University University of Washington

    9. In vivo SS-OCT imaging of crystalline lens sutures

      Explore OSA | OSA Publishing Ophthalmology
      In vivo SS-OCT imaging of crystalline lens sutures

      We demonstrate in vivo three-dimensional (3-D) visualization of crystalline lens sutures in healthy eyes using swept source optical coherence tomography (SS-OCT). Volumetric data sets of the crystalline lenses were acquired and processed to obtain enhanced contrast projection images and to extract suture patterns in both anterior and posterior lens. The results presented different types of the sutures including Y-sutures, simple and complex star sutures. Age-related changes in suture arrangement were characterized quantitatively. Crystalline lens suture imaging with SS-OCT might be a useful tool in fundamental studies on development and ageing of human lens.

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      Mentions: Nicolaus Copernicus University Ireneusz Grulkowski

    10. Detecting Mouse Squamous Cell Carcinoma from Submicron FF‐OCT Images by Deep Learning

      Explore Wiley Online Library Dermatology
      Detecting Mouse Squamous Cell Carcinoma from Submicron FF‐OCT Images by Deep Learning

      The standard medical practice for cancer diagnosis requires histopathology, which is an invasive and time‐consuming procedure. Optical coherence tomography (OCT) is an alternative that is relatively fast, non‐invasive, and able to capture three‐dimensional structures of epithelial tissue. Unlike most previous OCT systems, which cannot capture crucial cellular‐level information for squamous cell carcinoma (SCC) diagnosis, the full‐field OCT (FF‐OCT) technology used in this paper is able to produce images at sub‐micron resolution and thereby facilitates the development of a deep learning algorithm for SCC detection. Experimental results show that the SCC detection algorithm can ...

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      Mentions: National Taiwan University Sheng-Lung Huang

    11. OPtical Coherence Tomography Guided Coronary Stent IMplantation Compared to Angiography: A Multicenter Randomized TriaL in PCI

      Explore eurointervention.pcronline.com Cardiology
      OPtical Coherence Tomography Guided Coronary Stent IMplantation Compared to Angiography: A Multicenter Randomized TriaL in PCI

      AIMS: Randomized trials have demonstrated improvement in clinical outcomes with intravascular ultrasound (IVUS)-guided percutaneous coronary intervention (PCI) compared with angiography-guided PCI. The ILUMIEN III trial demonstrated non-inferiority of an optical coherence tomography (OCT)- versus IVUS-guided PCI strategy in achieving similar post-PCI lumen dimensions. ILUMIEN IV is a large-scale, multicenter, randomized trial designed to demonstrate the superiority of OCT- versus angiography-guided stent implantation in patients with high-risk clinical characteristics (diabetes) and/or complex angiographic lesions in achieving larger post-PCI lumen dimensions and improving clinical outcomes. METHODS AND RESULTS: ILUMIEN IV is a prospective, single-blind clinical investigation that will randomize between ...

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      Mentions: Columbia University Mount Sinai School of Medicine Cardiovascular Research Foundation

    12. Macrophage accumulation within coronary arterial wall in diabetic patients with acute coronary syndrome: a study with in-vivo intravascular imaging modalities

      Explore Cardiovascular Diabetology Cardiology
      Macrophage accumulation within coronary arterial wall in diabetic patients with acute coronary syndrome: a study with in-vivo intravascular imaging modalities

      Background and aims Macrophage accumulation in arteriosclerotic plaque of coronary arteries is involved in plaque destabilization. Atherosclerosis has been known to be progressive in patients with type 2 diabetes mellitus (DM). This study compared the features of 3-dimensional (3D) spatial distribution of macrophage accumulation within coronary artery wall between acute coronary syndrome (ACS) patients with DM (n = 20) and those without (non-DM, n = 20) by using intravascular ultrasound (IVUS) and optical coherence tomography (OCT). Methods The OCT-derived macrophage accumulation was measured within the proximal left anterior-descending artery. This measurement was performed for the whole vessel segment of interest, higher shear ...

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      Mentions: Boston Scientific Abbot

    13. Fracture resistance of extensive bulk-fill composite restorations after selective caries removal

      Explore scielo.br Dentistry
      Fracture resistance of extensive bulk-fill composite restorations after selective caries removal

      This study evaluated the effect of selective carious tissue removal on the fracture strength and failure mode of composite restorations in molars presenting only the buccal cusps. Deep cavities were prepared on the occlusal surface, and the lingual cusps were removed. Carious lesions in the middle of the pulpal wall were artificially induced with acetic acid (pH = 4.5) for 35 days. The demineralized dentin was left intact or was completely removed prior to restoration with a bulk-fill composite (n = 10). Images of the specimens were obtained by optical coherence tomography (OCT) before and after the caries induction/removal. The ...

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      Mentions: Anderson S. L. Gomes Federal University of Pernambuco

    14. OCT Captures Impressionistic Brushstrokes

      Explore osa-opn.org Art
      OCT Captures Impressionistic Brushstrokes

      Art conservators have enlisted a bevy of imaging techniques, including optical coherence tomography (OCT), to study valuable paintings and ensure their long-term preservation. Even though OCT can generate 3D images of scattering media with micrometer resolution and without destroying its subject, the method’s narrow field of view limits its ability to examine broad regions of an artist’s canvas. Researchers at two U.S. universities have built a hybrid scanning platform that couples OCT with a sampling algorithm to create 3D reconstructions of impressionist oil paintings (Appl. Opt., doi: 10.1364/AO.390326 ). Besides helping art historians to understand ...

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    15. See all articles

  2. Recent Articles From Around The Web

    2. Cone Photoreceptor Integrity assessed with Adaptive Optics Imaging after Laser-Pointer-Induced Retinal Injury

      Explore LWW Online Ophthalmology
      Cone Photoreceptor Integrity assessed with Adaptive Optics Imaging after Laser-Pointer-Induced Retinal Injury

      Purpose: To examine the three-dimensional foveal cone photoreceptor structure in a patient who had suffered laser pointer induced retinal injury . Methods: Patient underwent standard fundus photography and clinical spectral domain optical coherence tomography (SD-OCT) imaging. High-resolution imaging was performed using an Adaptive Optics -OCT-Scanning Laser Ophthalmoscope (AO-OCT-SLO). Results: AO imaging revealed loss of inner and outer segments of cone photoreceptors while the anterior retinal layers appeared healthy. Analysis of cone topology showed an increase in Voronoi domain area and a less regular hexagonal packing structure closer to the lesion site. Conclusion: Exposure to laser pointer radiation, however brief, can result ...

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      Mentions: The Ohio State University

    3. Quantitative assessment of macular microvasculature and radial peripapillary capillary plexus in the fellow eyes of patients with retinal vein occlusion using OCT angiography

      Explore ScienceDirect Ophthalmology
      Quantitative assessment of macular microvasculature and radial peripapillary capillary plexus in the fellow eyes of patients with retinal vein occlusion using OCT angiography

      Purpose To evaluate the macular microvasculature and radial peripapillary capillary (RPC) plexus in the fellow eyes of patients diagnosed with unilateral retinal vein occlusion (RVO), using optical coherence tomography angiography (OCTA). Methods Seventy-two fellow eyes of patients with unilateral RVO and 74 healthy control eyes were consecutively enrolled. All subjects underwent a complete ophthalmological assessment, including optical coherence tomography (OCT) and OCTA measurements. Foveal avascular zone (FAZ) area, macular vessel density (VD), and perfusion density (PD) of the superficial capillary plexus (SCP) were measured. The perfusion and flux index (FI) of the RPC plexus were measured using a 4.5 ...

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    4. Identification of the type of stent with three-dimensional optical coherence tomography: the SPQR study

      Explore eurointervention.pcronline.com Cardiology
      Identification of the type of stent with three-dimensional optical coherence tomography: the SPQR study

      Background: The ability of optical coherence tomography (OCT) to identify specific types of stent has never been systematically studied. Methods and results: A series of 212 consecutive patients with OCT from six international centres were retrospectively screened, finding 294 metallic stents or scaffolds in 146 patients. The sample was analysed by two blinded operators, applying a dedicated protocol in 4 steps to identify the type of stent: 1) 3D and automatic strut detection (ASD), 2) 3D tissue view, 3) Longitudinal view with ASD, 4) Mode “stent only” and ASD. The protocol correctly identified 285 stents (96.9%, kappa 0.965 ...

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      Mentions: Shanghai Jiao Tong University Juan Luis Gutiérrez-Chico Shengxian Tu

    7. Application of optical frequency domain imaging to recanalized unruptured internal carotid artery aneurysm treated by flow-diverting stent-assisted coiling

      Explore ScienceDirect Cardiology , Neurology
      Application of optical frequency domain imaging to recanalized unruptured internal carotid artery aneurysm treated by flow-diverting stent-assisted coiling

      Here we report the application of optical frequency domain imaging (OFDI), a new optical coherence tomography (OCT) device, for intravascular visualization in the treatment of a recanalized unruptured internal carotid artery aneurysm that was treated initially by stent-assisted coil embolization. OFDI revealed malapposition of the stent and lack of neointimal growth at the aneurysm neck, which was treated by deployment of a Pipeline Embolization Device to overlap the stent. An angiogram performed one year after the procedure revealed perfect healing of the aneurysm and OFDI clearly demonstrated good stent apposition and total endothelialization over the aneurysm neck.

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    8. Optical Coherence Tomography Angiography in idiopathic retinal vasculitis, aneurysms and neuroretinitis (IRVAN) syndrome: A case report

      Explore SAGE Journals Ophthalmology
      Optical Coherence Tomography Angiography in idiopathic retinal vasculitis, aneurysms and neuroretinitis (IRVAN) syndrome: A case report

      Purpose: Since its first description by Chang et al. in 1995, the diagnosis of Idiopathic retinal vasculitis, aneurysms and neuroretinitis (IRVAN) syndrome has been based on the findings of Fundus Fluorescein Angiography (FFA). Our purpose was to describe the utility of optical coherence tomography angiography (OCT-A) in its diagnosis and management. Case description: A 40-year-old female presented with bilateral blurred vision. Her best corrected visual acuity was at 8/10. Fundus examination revealed blurred disc margins, perivascular exudates, arterial sheaths and retinal hemorrhages bilaterally. FFA showed staining of the optic disc with dye leakage in the right eye, a punctuate ...

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    9. Detection of localized pulsatile motion in cutaneous microcirculation by speckle decorrelation optical coherence tomography angiography

      Explore SPIE Digital Library Dermatology
      Detection of localized pulsatile motion in cutaneous microcirculation by speckle decorrelation optical coherence tomography angiography

      Significance: Pulsatility is a vital characteristic of the cardiovascular system. Characterization of the pulsatility pattern locally in the peripheral microvasculature is currently not readily available and would provide an additional source of information, which may prove important in understanding the pathophysiology of arterial stiffening, vascular ageing, and their linkage with cardiovascular disease development. Aim: We aim to confirm the suitability of speckle decorrelation optical coherence tomography angiography (OCTA) under various noncontact/contact scanning protocols for the visualization of pulsatility patterns in vessel-free tissue and in the microvasculature of peripheral human skin. Results: Results from five healthy subjects show distinct pulsatile ...

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      Mentions: David D. Sampson University of Western Australia Qiang Wang

    10. Water wavenumber calibration for visible light optical coherence tomography

      Explore SPIE Digital Library
      Water wavenumber calibration for visible light optical coherence tomography

      Significance : Visible light optical coherence tomography (OCT) is emerging for spectroscopic and ultrahigh resolution imaging, but challenges remain. Depth-dependent dispersion limits retinal image quality and current correction approaches are cumbersome. Inconsistent group refractive indices during image reconstruction also limit reproducibility. Aim: To introduce and evaluate water wavenumber calibration (WWC), which corrects depth-dependent dispersion and provides an accurate depth axis in water. Approach: Enabled by a visible light OCT spectrometer configuration with a 3- to 4-dB sensitivity roll-off over 1 mm in air across a 90-nm bandwidth, we determine the spectral phase of a 1-mm water cell, an affine function of ...

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      Mentions: Vivek J. Srinivasan UC Davis

    11. Temporal changes of incomplete stent apposition during early phase after everolimus-eluting stent implantation: serial optical coherence tomography analyses at 2-week and 4-month

      Explore Home - Springer Cardiology
      Temporal changes of incomplete stent apposition during early phase after everolimus-eluting stent implantation: serial optical coherence tomography analyses at 2-week and 4-month

      The healing process of acute incomplete stent apposition (ISA) in the early phase after stent implantation has not been well understood. We evaluated the temporal changes of ISA during the early phase after everolimus-eluting stent (EES) implantation using serial optical coherence tomography (OCT) analyses. Serial OCT examinations were performed immediately post-stenting and 2-week and 4-month after EES implantation for patients with ST-segment elevation myocardial infarction. At the most proximal cross-section of the implanted stent, the prevalence of ISA and maximum ISA distance were serially evaluated. In 45 patients with ST-segment elevation myocardial infarction, serial OCT analyses at 2-week and 4-month ...

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    12. Spontaneous resolution of optic pit maculopathy: an OCT report

      Explore SAGE Journals Ophthalmology
      Spontaneous resolution of optic pit maculopathy: an OCT report

      The separation of the vitreous from the optic nerve head and the macula plays a primary role in the spontaneous resolution of optic disc pit (ODP) maculopathy. Optical coherence tomography (OCT) helps in the non-invasive monitoring of this condition, when treated conservatively. The aim of this report was to describe a pediatric case of spontaneously resolved ODP maculopathy, managed conservatively and monitored by means of spectral domain (SD)-OCT. A 14-year-old girl presented with severe visual loss in the right eye (RE). Fundus examination demonstrated a temporal ODP with altered foveal reflex. The SD-OCT B-scans revealed severe intraretinal schisis-like changes ...

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      Mentions: Giuseppe Querques Università Vita-Salute San Raffaele

    13. SiameseGAN: A Generative Model for Denoising of Spectral Domain Optical Coherence Tomography Images

      Explore IEEE Xplore Ophthalmology
      SiameseGAN: A Generative Model for Denoising of Spectral Domain Optical Coherence Tomography Images

      Optical coherence tomography (OCT) is a standard diagnostic imaging method for assessment of ophthalmic diseases. The speckle noise present in the high-speed OCT images hampers its clinical utility, especially in Spectral-Domain Optical Coherence Tomography (SDOCT). In this work, a new deep generative model, called as SiameseGAN, for denoising Low signal-to-noise ratio (LSNR) B-scans of SDOCT has been developed. SiameseGAN is a Generative Adversarial Network (GAN) equipped with a siamese twin network. The siamese network module of the proposed SiameseGAN model helps the generator to generate denoised images that are closer to groundtruth images in the feature space, while the discriminator ...

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    14. Classification of advanced and early stages of diabetic retinopathy from non-diabetic subjects by an ordinary least squares modeling method applied to OCTA images

      Explore OSA | OSA Publishing Ophthalmology
      Classification of advanced and early stages of diabetic retinopathy from non-diabetic subjects by an ordinary least squares modeling method applied to OCTA images

      As the prevalence of diabetic retinopathy (DR) continues to rise, there is a need to develop computer-aided screening methods. The current study reports and validates an ordinary least squares (OLS) method to model optical coherence tomography angiography (OCTA) images and derive OLS parameters for classifying proliferative DR (PDR) and no/mild non-proliferative DR (NPDR) from non-diabetic subjects. OLS parameters were correlated with vessel metrics quantified from OCTA images and were used to determine predicted probabilities of PDR, no/mild NPDR, and non-diabetics. The classification rates of PDR and no/mild NPDR from non-diabetic subjects were 94% and 91%, respectively. The ...

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      Mentions: UCLA

    15. Incidence and Predictors of Neoatherosclerosis in Patients with Early In-Stent Restenosis Determined Using Optical Coherence Tomography

      Explore jstage.jst.go.jp Cardiology
      Incidence and Predictors of Neoatherosclerosis in Patients with Early In-Stent Restenosis Determined Using Optical Coherence Tomography

      Summary In-stent restenosis (ISR) still exists after drug-eluting stent (DES) implantation, even up to one year. The incidence and risk factors for neoatherosclerosis in patients with early ISR have not yet been elucidated. Here, we used optical coherence tomography (OCT) to evaluate the incidence and predictors of neoatherosclerosis in patients with early ISRs. OCT was performed on ISR lesions in 185 patients in order to detect neoatherosclerosis. The median follow-up was 180 days, and neoatherosclerosis was detected in 37% of early ISR lesions. According to the presence of neoatherosclerosis, patients with ISR were divided into two groups: neoatherosclerosis (group A ...

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      Mentions: Harbin Medical University Bo Yu
      16. See all articles
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  6. Organizations in the News

    1. (3 articles) The Ohio State University
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    3. (2 articles) University of Western Australia
    4. (2 articles) Harvard University
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    6. (2 articles) Shanghai Jiao Tong University
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    1. (2 articles) David D. Sampson
    2. (2 articles) Sharon F. Freedman
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    12. (1 articles) Tetsumin Lee
    13. (1 articles) Bo Yu
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  8. OCT Companies in the News

    1. (2 articles) Topcon Medical Systems
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  9. Picture Gallery

    HP-OCT™ wins Victorian AEEA award – nominated for Sir William Hudson award Postdoctoral Scholar in High Resolution Retinal Imaging at The Ohio State University Semi-automated registration and segmentation for gingival tissue volume measurement on 3D OCT images Pet laser pointers have enough power to “blast away” cells in the back of the eye Influence of tissue fixation on depth-resolved birefringence of oral cavity tissue samples Industrialization Potential of Optics in Biomedicine (On-Line Conference October 7 & 8, 2020) Correlative infrared optical coherence tomography and hyperspectral chemical imaging The optoretinogram reveals the primary steps of phototransduction in the living human eye In vivo SS-OCT imaging of crystalline lens sutures Detecting Mouse Squamous Cell Carcinoma from Submicron FF‐OCT Images by Deep Learning OPtical Coherence Tomography Guided Coronary Stent IMplantation Compared to Angiography: A Multicenter Randomized TriaL in PCI Macrophage accumulation within coronary arterial wall in diabetic patients with acute coronary syndrome: a study with in-vivo intravascular imaging modalities

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    1. After planning a procedure with angiography alone, we exposed physicians to all the information provided by OCT on the same blockage and were able to demonstrate the significant impact that the information had on our decisions...OCT takes the guesswork out of angiography, offering doctors real-time high-quality granularity and precision when performing PCIs, and helping doctors make real-time decisions in the cath lab.
      By Hiram G. Bezerra
    2. Previous research has seen a thinning of the retina in Alzheimer's patients, but by adding a light-scattering technique to the measurement, we've found that the retinal nerve fiber layer is also rougher and more disordered...Our hope is that we can use this insight to create an easy and cheap screening device that wouldn't only be available at your doctor's office, but at places like your local pharmacy as well
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    6. It is such a huge honor to be recognized with this prestigious industry award for best healthcare product in 2020, and we’d like to thank SPIE and Photonics Media for sponsoring this incredible opportunity...Our team is working hard to provide better options to millions of patients who suffer from middle ear infections. Following our recent 510(k) clearance from the FDA, we cannot wait to see how the TOMi Scope impacts the standard of care for this incredibly common disease.
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    7. We developed an algorithm that can be used to automatically analyze optical coherence tomography (OCT) images of the retina to predict whether a patient is likely to respond to anti-VEGF treatments...This research represents a step toward precision medicine, in which such predictions help clinicians better select first-line therapies for patients based on specific disease conditions.
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    9. We hope that this new lab between SNEC-SERI and NTU will be the start of an important programme to utilise engineering solutions to help and improve care of our patients with eye problems.
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