1. Feature Of The Week: Using Optical Coherence Tomography For Anti-Spoof Fingerprint Detection

    Fingerprint biometrics, including automated fingerprint identification systems (AFIS), currently occupy two-thirds of the biometric market and are expected to remain the dominant player in this area. The technology can be integrated into small, compact devices and the instruments are relatively fast. However, the overall success of using fingerprints for identification and verification purposes greatly depends upon the quality of the fingerprints initially enrolled. For example, fingerprints captured from older people are significantly lower quality than those from younger people due primarily to ridge-wearing and difficulty of interacting effectively with conventional fingerprint scanners. The ramification is that the problem of obtaining prints of sufficient quality inexorably becomes worse as society ages. Whilst often noticed, spoof fingerprints can go undetected.

    We propose the use of correlation mapping optical coherence tomography (cmOCT) to deliver additional biometrics associated with the finger that could complement existing fingerprint technology for law enforcement applications. The current study extends the existing fingerprint paradigm by measuring additional biometrics associated with sub-surface finger tissue such as sub-surface fingerprints, sweat glands, and the pattern of the capillary bed to yield a user-friendly cost effective and anti- spoof multi-mode biometric solution associated with the finger. To our knowledge no other method has been able to capture sub-surface fingerprint, papillary pattern and horizontal vessel pattern in a single scan or to show the correspondence between these patterns in live adult human fingertip. Unlike many current technologies this approach incorporates ‘liveness’ testing by default. The ultimate output is a biometric module which is difficult to defeat and complements fingerprint scanners that currently are used in border control and law enforcement applications.

    For more information see recent Article. Courtesy of Azhar Zam from National University of Ireland, Galway. To share this article click Here.

  2. Featured Articles

    1. Accurate prediction of collapse temperature using optical coherence tomography-based freeze-drying microscopy

      Explore Wiley Online Library NDE/NDT , Other Non-Medical
      Accurate prediction of collapse temperature using optical coherence tomography-based freeze-drying microscopy

      The objective of this study was to assess the feasibility of developing and applying a laboratory tool that can provide three-dimensional product structural information during freeze-drying and which can accurately characterize the collapse temperature ( T c ) of pharmaceutical formulations designed for freeze-drying. A single-vial freeze dryer coupled with optical coherence tomography freeze-drying microscopy (OCT–FDM) was developed to investigate the structure and T c of formulations in pharmaceutically relevant products containers (i.e., freeze-drying in vials). OCT–FDM was used to measure the T c and eutectic melt of three formulations in freeze-drying vials. The T c as measured by ...

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      Mentions: Daniel X. Hammer Physical Sciences Incorporated University of Connecticut

    2. Visualisation of a coronary stent presenting late mechanical failure in an aberrant left circumflex artery with coronary computed tomography angiography and optical coherence tomography

      Explore eurointervention.org Cardiology
      Visualisation of a coronary stent presenting late mechanical failure in an aberrant left circumflex artery with coronary computed tomography angiography and optical coherence tomography

      A 56-year-old male was admitted with NSTEMI and underwent percutaneous coronary intervention with bare metal (cobalt-chromium) stent implantation (3.0×24 mm, 16 atm, post-dilated with 3.0×20 mm non-compliant balloon, 20 atm) in the mid segment of an anomalous circumflex artery (retroaortic course from the right sinus of Valsalva). The patient remained asymptomatic for five years post-procedure, when he presented with mild atypical chest pain. Myocardial stress perfusion scintigraphy detected no transient ischaemia; however, due to his persisting symptoms, a coronary computed tomography angiography was performed. This revealed restenosis and chronic recoil in the implanted stent (Online Figure ...

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      Mentions: Lightlab C7 XR OCT Imaging System St. Jude Medical

    3. St. Jude Medical Announces European Approval of 3-D Vessel Reconstruction Technology to Aid Physicians in Stent Placement

      Explore Optical Coherence Tomography News Cardiology
      St. Jude Medical Announces European Approval of 3-D Vessel Reconstruction Technology to Aid Physicians in Stent Placement

      St. Jude Press Release - St. Jude Medical, Inc. (NYSE:STJ), a global medical device company, today announced CE Mark approval of its ILUMIEN™ OPTIS™ PCI Optimization System™, a new technology designed to provide physicians with a comprehensive disease assessment tool for treating patients with coronary artery disease (CAD). The system will be on display for the first time in Europe during EuroPCR. 3-D image of a stent inside a coronary artery taken using the ILUMIEN(TM) OPTIS(TM) (Photo: St. Jude Medical, Inc.) The ILUMIEN OPTIS system provides enhancements to the ILUMIEN ™ system, including first-of-its-kind stent planning software tools to ...

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      Mentions: Giulio Guagliumi St. Jude Medical Frank J. Callaghan

    4. Inter-Scan Reproducibility of Geometric Coronary Artery Measurements Using Frequency-Domain Optical Coherence Tomography

      Explore jstage.jst.go.jp Cardiology
      Inter-Scan Reproducibility of Geometric Coronary Artery Measurements Using Frequency-Domain Optical Coherence Tomography

      Frequency-domain optical coherence tomography (FD-OCT) is a novel technology which provides high-resolution cross-sectional images of coronary arteries. The aim of this study was to evaluate the inter-scan reproducibility of geometric FD-OCT measurements in the clinical setting. We examined 20 coronary lesions using FD-OCT. Following the FD-OCT image acquisition (1 st pullback), and after the disengagement and re-engagement of the guiding catheter, an additional acquisition (2 nd pullback) was performed using a new FD-OCT catheter. There was excellent correlation for minimum lumen area ( r = 0.99, P < 0.001), lesion length ( r = 0.99, P < 0.001) and lumen volume ( r ...

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      Mentions: Wakayama Medical University Takashi Kubo Takashi Tanimoto

    5. Interest of High Definition Optical Coherent Tomography (HD‐OCT) for imaging of melanoma

      Explore Wiley Online Library Dermatology
      Interest of High Definition Optical Coherent Tomography (HD‐OCT) for imaging of melanoma

      We read with interest two recent studies which established that High Definition Optical Coherent Tomography (HD-OCT), a newly released skin imaging technique, facilitates the in vivo diagnosis of non-melanoma skin cancers (1, 2). However, to the best of our knowledge there is no data available regarding HD-OCT and melanoma. A 61-year-old man, skin type II, with a previous history of melanoma 10 years before consulted for a follow-up visit. Clinical and dermoscopic examination pointed to two suspicious pigmented lesions in the right pectoral region and on the left scapula. RCM examination using a commercially available VivaScope ® 1500 (Lucid-Tech Inc., Henrietta ...

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      Mentions: AGFA Healthcare AGFA SKINTELL

    6. Full-Field Thickness Distribution of Human Tympanic Membrane Obtained with Optical Coherence Tomography

      Explore Home - Springer Otolaryngology
      Full-Field Thickness Distribution of Human Tympanic Membrane Obtained with Optical Coherence Tomography

      The full-field thickness distribution, three-dimensional surface model and general morphological data of six human tympanic membranes are presented. Cross-sectional images were taken perpendicular through the membranes using a high-resolution optical coherence tomography setup. Five normal membranes and one membrane containing a pathological site are included in this study. The thickness varies strongly across each membrane, and a great deal of inter-specimen variability can be seen in the measurement results, though all membranes show similar features in their respective relative thickness distributions. Mean thickness values across the pars tensa ranged between 79 and 97 μm; all membranes were thinnest in the ...

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      Mentions: Adrian G. Podoleanu University of Kent Adrian Bradu

    7. NinePoint Medical Announces U.S. Commercial Availability of the NvisionVLE™ Imaging System

      Explore Optical Coherence Tomography News Gastroenterology , Other Business News
      NinePoint Medical Announces U.S. Commercial Availability of the NvisionVLE™ Imaging System

      NinePoint Press Release - NinePoint Medical, Inc., an emerging leader in the development of medical devices for advanced optical imaging, today announced the commercial launch of its proprietary NvisionVLE ™ Imaging System in the United States. In addition, NinePoint today announced the launch of its newly redesigned website, www.ninepointmedical.com . In December 2011, the NvisionVLE Imaging System received 510(k) clearance from the U.S. Food and Drug Administration for use as an imaging tool in the evaluation of human tissue microstructure by providing two-dimensional, cross sectional, real-time depth visualization. Last month, NinePoint received 510(k) clearance to expand the System ...

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      Mentions: Massachusetts General Hospital FDA NinePoint Medical

    8. OCT imaging market led by Carl Zeiss and St. Jude Medical

      Explore uk.finance.yahoo.com Other Business News
      OCT imaging market led by Carl Zeiss and St. Jude Medical

      The optical coherence tomography imaging market (OCT) is estimated to have reached a valuation of $645.4 million by the end of 2012, increasing from approximately $525.7 million in 2010. Optical coherence tomography is an optical signal acquisition and processing method. It captures micrometer-resolution, three-dimensional images from within optical scattering media (e.g., biological tissue). Optical coherence tomography is an interferometric technique, typically employing near-infrared light. The use of relatively long wavelength light allows it to penetrate into the scattering medium. OCT is widely accepted for clinical diagnostics in ophthalmology, dentistry, cardiology, dermatology and also has broadened its application ...

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      Mentions: Carl Zeiss Meditec St. Jude Medical

    9. Noninvasive three-dimensional live imaging methodology for the spindles at meiosis and mitosis

      Explore SPIE | Journal
      Noninvasive three-dimensional live imaging methodology for the spindles at meiosis and mitosis

      The spindle plays a crucial role in normal chromosome alignment and segregation during meiosis and mitosis. Studying spindles in living cells noninvasively is of great value in assisted reproduction technology (ART). Here, we present a novel spindle imaging methodology, full-field optical coherence tomography (FF-OCT). Without any dye labeling and fixation, we demonstrate the first successful application of FF-OCT to noninvasive three-dimensional (3-D) live imaging of the meiotic spindles within the mouse living oocytes at metaphase II as well as the mitotic spindles in the living zygotes at metaphase and telophase. By post-processing of the 3-D dataset obtained with FF-OCT, the ...

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      Mentions: Tsinghua University Ping Xue Jing-gao Zheng

    10. Automated non-rigid registration and mosaicing for robust imaging of distinct retinal capillary beds using speckle variance optical coherence tomography

      Explore opticsinfobase.org Ophthalmology
      Automated non-rigid registration and mosaicing for robust imaging of distinct retinal capillary beds using speckle variance optical coherence tomography

      Variance processing methods in Fourier domain optical coherence tomography (FD-OCT) have enabled depth-resolved visualization of the capillary beds in the retina due to the development of imaging systems capable of acquiring A-scan data in the 100 kHz regime. However, acquisition of volumetric variance data sets still requires several seconds of acquisition time, even with high speed systems. Movement of the subject during this time span is sufficient to corrupt visualization of the vasculature. We demonstrate a method to eliminate motion artifacts in speckle variance FD-OCT images of the retinal vasculature by creating a composite image from multiple volumes of data ...

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      Mentions: Joseph A. Izatt Duke University Sina Farsiu

    11. Intravascular optical coherence tomography imaging at 3200 frames per second

      Explore opticsinfobase.org Cardiology
      Intravascular optical coherence tomography imaging at 3200 frames per second

      We demonstrate intravascular optical coherence tomography (OCT) imaging with frame rate up to 3.2 kHz (192,000 rpm scanning). This was achieved by using a custom-built catheter in which the circumferential scanning was actuated by a 1.0 mm diameter synchronous motor. The OCT system, with an imaging depth of 3.7 mm (in air), is based on a Fourier domain mode locked laser operating at an A-line rate of 1.6 MHz. The diameter of the catheter is 1.1 mm at the tip. Ex vivo images of human coronary artery (78.4 mm length) were acquired at ...

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      Mentions: Robert A. Huber Erasmus Medical Center Gijs van Soest

    12. Frequency multiplexed long range swept source optical coherence tomography

      Explore opticsinfobase.org
      Frequency multiplexed long range swept source optical coherence tomography

      We present a novel swept source optical coherence tomography configuration, equipped with acousto-optic deflectors that can be used to simultaneously acquire multiple B-scans originating from different depths. The sensitivity range of the configuration is evaluated while acquiring five simultaneous B-scans. Then the configuration is employed to demonstrate long range B-scan imaging by combining two simultaneous B-scans from a mouse head sample

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      Mentions: Adrian G. Podoleanu University of Kent Adrian Bradu

    13. Mirrorcle Technologies announces availability of 4.2mm diameter MEMS 2-Axis mirrors

      Explore Optical Coherence Tomography News Other Business News
      Mirrorcle Technologies announces availability of 4.2mm diameter MEMS 2-Axis mirrors

      Mirrorcle Technologies Press Release - Mirrorcle Technologies announces availability of 4.2mm diameter MEMS mirrors Mirrorcle Technologies, Inc (MTI), the California-based manufacturer of patented, gimbal-less MEMS micromirror devices, today announces the availability of a larger category of mirrors. Until now, the company has been offering integrated mirror devices ranging from 0.8mm to 1.7mm in diameter, and bonded mirrors from 0.8mm to 3.6mm in diameter. Mirrorcle’s bonded MEMS mirror devices are modular in design, consisting of an actuator ‘engine’ and a mirror of customer-selected size. With a variety of different MEMS actuators, a selection of aluminum or ...

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    14. Fossilized Teeth as a New Robust and Reproducible Standard for Polarization-Sensitive Optical Coherence Tomography

      Explore Hindawi Publishing Corporation Dentistry
      Fossilized Teeth as a New Robust and Reproducible Standard for Polarization-Sensitive Optical Coherence Tomography

      A clinical need exists for a cheap and efficient standard for polarization sensitive optical coherence tomography (PS-OCT). We utilize prehistoric fossilized teeth from the Megalodon shark and European horse as an unconventional, yet robust standard. Given their easy accessibility and the microstructural consistency conferred by the process of fossilization, they provide a means of calibration to reduce error from sources such as catheter bending and temperature changes. We tested the maximum difference in birefringence values in each tooth and found the fossilized teeth to be fast and repeatable. The results were compared to measurements from bovine meniscus, tendon, and destroyed ...

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      Mentions: Brigham and Women’s Hospital Mark E. Brezinski Harvard University

    15. Imaging of non-tumorous and tumorous human brain tissues with full-field optical coherence tomography

      Explore ScienceDirect Neurology , Oncology
      Imaging of non-tumorous and tumorous human brain tissues with full-field optical coherence tomography

      A prospective study was performed on neurosurgical samples from 18 patients to evaluate the use of full-field optical coherence tomography (FF-OCT) in brain tumor diagnosis. FF-OCT captures en face slices of tissue samples at 1 μm resolution in 3D to a penetration depth of around 200 μm. A 1 cm 2 specimen is scanned at a single depth and processed in about 5 min. This rapid imaging process is non-invasive and requires neither contrast agent injection nor tissue preparation, which makes it particularly well suited to medical imaging applications. Temporal chronic epileptic parenchyma and brain tumors such as meningiomas, low-grade ...

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      Mentions: Claude Boccara Fabrice Harms LLTech

    16. The use of dextran and carbon dioxide for optical coherence tomography in the superficial femoral artery

      Explore Journal of Vascular Surgery Cardiology
      The use of dextran and carbon dioxide for optical coherence tomography in the superficial femoral artery

      The following case report describes using carbon dioxide (CO 2 ) as contrast media for intravascular optical coherence tomography (OCT) imaging in the superficial femoral artery. For initial OCT imaging, 20 mL of iodinated contrast was used during automated pullback. This was followed by 20 mL of hand-injected dextran 40 in normal saline, and finally hand-injected 50 mL of CO 2 . CO 2 gave comparable erythrocyte clearance and imaging quality compared with dextran and iodinated contrast. To our knowledge, this is the first reported case using both dextran and CO 2 with OCT imaging of the superficial femoral artery. Using CO ...

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      Mentions: Case Western Reserve University Hiram G. Bezerra

    17. In vivo detection of lipid-rich plaque by using a 40-MHz intravascular ultrasound: a comparison with optical coherence tomography findings

      Explore Home - Springer Cardiology
      In vivo detection of lipid-rich plaque by using a 40-MHz intravascular ultrasound: a comparison with optical coherence tomography findings

      iMAP™ has recently been introduced as a new tissue characterization method using the 40-MHz intravascular ultrasound (IVUS). However, few data have been published on the comparative findings of other imaging modalities in vivo. We examined 108 matched lesions from 70 patients (35 with stable angina and 35 with acute coronary syndrome) that underwent percutaneous coronary intervention (PCI) using pre-PCI OCT and IVUS. Identification of OCT-derived lipid-rich plaques and thin-cap fibroatheroma (TCFA) was performed using iMAP™. OCT-derived lipid-rich plaques and TCFAs were detected in 56 (51.8 %) and 20 (18.6 %) lesions, respectively. The iMAP™ analysis identified significantly greater percentage of ...

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      Mentions: Tokyo Medical & Dental University Tsunekazu Kakuta Tetsumin Lee

    18. Functional and structural age-related changes in the scalp skin of Caucasian women

      Explore Wiley Online Library Dermatology
      Functional and structural age-related changes in the scalp skin of Caucasian women

      Background Ageing of the skin, being chronological or sun induced is highly documented. Scalp, as a specific skin site, has, however, received little attention. This work attempted to describe functional and structural alterations that occur in scalp skin with ageing. Methods Two different age groups (N = 15 each; 30 ± 3 and 62 ± 2 y.o. respectively) of Caucasian women participated in the study. Some functional parameters (TEWL, Sebum level, Hydration, T°) were recorded on the vertex part of the scalp, after having cut the hair flat on the scalp surface. Imaging of some structural criteria was carried out using high-frequency ...

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    19. Optical coherence tomography for vulnerability assessment of sandstone

      Explore opticsinfobase.org NDE/NDT , Other Non-Medical
      Optical coherence tomography for vulnerability assessment of sandstone

      Sandstone is an important cultural heritage material, in both architectural and natural settings, such as neolithic rock art panels. The majority of deterioration effects in porous materials such as sandstone are influenced by the presence and movement of water through the material. The presence of water within the porous network of a material results in changes in the optical coherence tomography signal intensity that can be used to monitor the wetting front of water penetration of dry porous materials at various depths. The technique is able to detect wetting front velocities from 1     cm     s − 1 to 10 − 6     cm ...

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      Mentions: Nottingham Trent University Haida Liang

    20. Symposium on Dental OCT June 20th 2013 in Tokyo, Japan.

      Explore Optical Coherence Tomography News Dentistry
      Symposium on Dental OCT June 20th 2013 in Tokyo, Japan.

      Tokyo Medial and Dental University will hold a special symposium in Tokyo on June 20 (Thu) on the development and application of Optical Coherence Tomography in Dentistry. The symposium is sponsored by Tokyo Medical and Dental University, and some of the pioneers of dental OCT from Japan and US will talk about the latest developments in the field (see the list of speakers at http://www.tmdu.net/oct/ ) . All interested individuals including students, researchers and company representatives are invited to attend this event. Registration fees will be waived for those who pre-register by June 3 online at http://www ...

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      Mentions: University of Minnesota Daniel S. Fried UCLA

    21. Bioptigen introduces 1 µm resolution SD-OCT imaging system in collaboration with NKT Photonics supercontinuum white light laser source at ARVO conference in Seattle

      Explore Optical Coherence Tomography News Ophthalmology , Other Business News , Partnership
      Bioptigen introduces 1 µm resolution SD-OCT imaging system in collaboration with NKT Photonics supercontinuum white light laser source at ARVO conference in Seattle

      Bioptigen/NKT Press Release - Bioptigen Inc. has introduced 1 um axial resolution imaging to its line of Envisu TM spectral domain OCT systems. The company has now integrated NKT Photonics SuperK supercontinuum laser with Bioptigen’s new 300 nm spectrometer to achieve a breakthrough in ophthalmic imaging for preclinical research. “The progression to 1 um extreme resolution imaging is an exciting advancement for our Envisu R-Class research product line”, said Dr. Eric Buckland, CEO of Bioptigen. “The importance of this innovation is that it offers researchers true cellular-level in vivo optical histology. This Extreme High Resolution (XHR) capability is unlocked ...

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      Mentions: Eric L. Buckland Bioptigen NKT Photonics

    22. Full-Time PhD Scholarship in Advanced Optical Imaging and Nanomaterial Nottingham Trent University, School of Science & Technology

      Explore Optical Coherence Tomography News Jobs & Studentships
      Full-Time PhD Scholarship in Advanced Optical Imaging and Nanomaterial Nottingham Trent University, School of Science & Technology

      Advanced non-invasive optical imaging techniques such as optical coherence tomography (OCT) and hyperspectral imaging have found increasing applications in a wide range of disciplines from biomedical science to archaeology. A variety of state-of-the-art OCT and spectral imaging instruments have been developed in our group for specific material imaging applications. This project will develop methods for non-invasive material identification, dynamic imaging of novel nanomaterial (as both functional and contrast agents) in collaboration with colleagues in chemistry. One of the main aspects of the applications is on imaging of cave paintings along the Silk Road at a UNESCO world heritage site for ...

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      Mentions: Nottingham Trent University Haida Liang

    23. Volumetric image mining based on decomposition and graph analysis: An application to retinal optical coherence tomography

      Explore IEEE Xplore Ophthalmology
      Volumetric image mining based on decomposition and graph analysis: An application to retinal optical coherence tomography

      In this paper, we introduce a method for classifying volumetric images using a decomposition and graph analysis based method. Volume decomposition plays an important role in simplifying Three-Dimensional (3-D) volumes so as to enhance their analysis. Hierarchical decomposition techniques incrementally divide a given 3-D volume into sub-volumes according to some critical function and then (typically) represent the decomposition as a tree. The issue is the nature of the critical function which dictates when the decomposition should be stopped. Broadly the decomposition should be stopped whenever homogeneous sub-volumes are reached. The question is how we define homogeneity in this context. In ...

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    24. See all articles

  3. Recent Articles From Around The Web

    1. First International En Face OCT Congress in Rome December 14 2013

      Explore Optical Coherence Tomography News
      First International En Face OCT Congress in Rome December 14 2013

      The First international meeting on “en face”OCT in Rome Saturday December 14. Co-organizers are Bruno Lumbroso (Rome) Philip Rosenfeld (Miami) and Gabriel Coscas (Paris). Duration one day. We will discuss next developments of clinical “en face” OCT and clinical applications of this technique. For more information click HERE . Meeting Site ( www.symposiacongressi.eu and secretariat anna.porro@symposiacongressi.eu )).

      Read Full Article
      Mentions: Philip J. Rosenfeld Gabriel J. Coscas University of Miami

    2. Feature Of The Week 5/19/13: Using Optical Coherence Tomography For Anti-Spoof Fingerprint Detection

      Explore Optical Coherence Tomography News Other Non-Medical
      Feature Of The Week 5/19/13: Using Optical Coherence Tomography For Anti-Spoof Fingerprint Detection

      Fingerprint biometrics, including automated fingerprint identification systems (AFIS), currently occupy two-thirds of the biometric market and are expected to remain the dominant player in this area. The technology can be integrated into small, compact devices and the instruments are relatively fast. However, the overall success of using fingerprints for identification and verification purposes greatly depends upon the quality of the fingerprints initially enrolled. For example, fingerprints captured from older people are significantly lower quality than those from younger people due primarily to ridge-wearing and difficulty of interacting effectively with conventional fingerprint scanners. The ramification is that the problem of obtaining ...

      Read Full Article
      Mentions: Kirill V. Larin University of Houston Hrebesh M. Subhash

    3. Real-Time Subglottic Stenosis Imaging Using Optical Coherence Tomography in the Rabbit

      Explore JAMA Network Otolaryngology
      Real-Time Subglottic Stenosis Imaging Using Optical Coherence Tomography in the Rabbit

      Importance Subglottic stenosis (SGS) is a severe, acquired, potentially life-threatening disease that can be caused by endotracheal tube intubation. Newborns and neonates are particularly susceptible to SGS owing to the small caliber of their airway. Objective To demonstrate optical coherence tomography (OCT) capabilities in detecting injury and scar formation using a rabbit model. Optical coherence tomography may provide a noninvasive, bedside or intensive care unit modality for the identification of early airway trauma with the intention of preventing progression to SGS and can image the upper airway through an existing endotracheal tube coupled with a small fiber-optic probe. Design Rabbits ...

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      Mentions: Zhongping Chen UC Irvine Brian J. F. Wong

    4. Longitudinal fundus and retinal studies with SD-OCT: a comparison of five mouse inbred strains

      Explore Home - Springer Ophthalmology
      Longitudinal fundus and retinal studies with SD-OCT: a comparison of five mouse inbred strains

      Spectral domain optical coherence tomography (SD-OCT) has recently been established as a method for in vivo imaging of fundus and retina in the mouse. It enables more effective studies of retinal diseases including investigations of etiopathologic mechanisms. In order to learn more about longitudinal fundus development and to enable recognition of disease-associated irregularities, we performed confocal scanning laser ophthalmoscopy (cSLO) and SD-OCT measurements in the inbred strains C57BL/6J, C3HeB/FeJ, FVB/NCrl, BALB/cByJ, and 129S2/SvJ when they were between 2 and 6 months of age. In general, cSLO and SD-OCT data did not reveal sex-specific or unilateral ...

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      Mentions: Technical University of Munich

    5. Early vascular healing with biodegradable polymer coated sirolimus-eluting coronary stent implantation: assessed by optical coherence tomography results at 4-month follow-up

      Explore Edizioni Minerva Medica Cardiology
      Early vascular healing with biodegradable polymer coated sirolimus-eluting coronary stent implantation: assessed by optical coherence tomography results at 4-month follow-up

      Aim: The aim of this study was to evaluate the strut apposition and neointimal coverage of Supralimus-Core stent struts at 4 months after implantation using optical coherence tomography (OCT). Methods: The Supralimus-Core OCT study is a retrospective, single-center study evaluating strut apposition and neointimal coverage with OCT at 4 months after stent implantation. A total of 12 patients, who had 15 stents implanted were included in the study. The OCT was obtained using a C7-XR FD-OCT (frequency-domain OCT) intravascular imaging system. Strut apposition, neointimal hyperplasia (NIH) thickness and stent coverage on each stent strut were evaluated. Results: A total of ...

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      Mentions: National Institutes of Health Lightlab C7 XR OCT Imaging System St. Jude Medical

    6. Longitudinal extent of lipid pool assessed by optical coherence tomography predicts microvascular no-reflow after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction

      Explore Journal of Cardiology Cardiology
      Longitudinal extent of lipid pool assessed by optical coherence tomography predicts microvascular no-reflow after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction

      Background Distal embolization during percutaneous coronary intervention (PCI) may deteriorate microvascular reperfusion in patients with ST-elevation myocardial infarction (STEMI). Reperfusion at the coronary microvascular level is important for STEMI and culprit plaque is associated with distal embolization and microvascular reperfusion. ST-segment resolution (ST-R) in the electrocardiogram reflects microvascular reperfusion after primary PCI. Longitudinal extent of lipid pool assessed by optical coherence tomography (OCT) may predict the risk of failure of microvascular reperfusion after primary PCI. Methods and results This study consisted of 39 patients with STEMI who underwent primary PCI within 24 h after the onset of chest pain. Immediately ...

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    7. Global OCT imaging market: $645 million industry by 2012

      Explore Market Research Reports Other Business News
      Global OCT imaging market: $645 million industry by 2012

      The global OCT imaging market (optical coherence tomography) is suggested to have reached a value of around $525.7 million in 2010, and is believed to have then grown to a total of $645.4 million by the end of 2012. Optical coherence tomography (OCT) is a relatively new technology for performing high-resolution, cross-sectional imaging of tissue structure on the micron scale in situ and in real time. OCT has emerged as a powerful optical imaging instrument and technology. OCT performs high-resolution, cross-sectional tomographic imaging of the internal structure in 3-D materials, including biological tissues. The features of OCT that ...

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      Mentions: FDA

    8. Influence of Cataract Surgery on Optical Coherence Tomography and Neurophysiology Measurements in Patients With Retinitis Pigmentosa

      Explore American Journal of Ophthalmology Ophthalmology
      Influence of Cataract Surgery on Optical Coherence Tomography and Neurophysiology Measurements in Patients With Retinitis Pigmentosa

      Purpose To evaluate the effect of uncomplicated cataract phacoemulsification on the measurements of visual evoked potentials (VEP), pattern electroretinogram (PERG), and macular and retinal nerve fiber layer (RNFL) using 2 spectral-domain optical coherence tomography (OCT) instruments, the Cirrus OCT (Carl Zeiss Meditech) and Spectralis OCT (Heidelberg Engineering), in patients with retinitis pigmentosa (RP), and to assess the reliability of the OCT measurements before and after cataract surgery. Design Observational cross-sectional study. Methods Thirty-five eyes of 35 patients with RP (20 men and 15 women, 45-66 years) who underwent cataract phacoemulsification were studied. At 1 month before and 1 month after ...

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      Mentions: Heidelberg Engineering Carl Zeiss Meditec Miguel Servet University Hospital

    9. Analysis of the Morphology and Vascular Layers of the Choroid in Retinitis Pigmentosa Using Spectral-Domain OCT

      Explore Healio.com Ophthalmology
      Analysis of the Morphology and Vascular Layers of the Choroid in Retinitis Pigmentosa Using Spectral-Domain OCT

      BACKGROUND AND OBJECTIVE: To analyze choroidal morphology and vascular layers in eyes with retinitis pigmentosa (RP) using spectral-domain optical coherence tomography. PATIENTS AND METHODS: Cross-sectional, retrospective analysis of 14 patients (14 eyes) with RP and 33 healthy subjects (33 eyes) who underwent high-definition one-line raster scanning at a single center. Two independent raters evaluated the morphology, thickness, and vascular layers of the choroid in both groups. RESULTS: The choroid had an irregular shape in 11 of 14 eyes (79%) with RP. The thickest point of choroid was not subfoveal as in healthy eyes, and exaggerated nasal thinning of the choroid ...

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      Mentions: Optovue Jay S. Duker University of São Paulo

    10. Congenital Hypertrophy of the Retinal Pigment Epithelium: Choroidal Cavitation Demonstrated on Spectral-Domain OCT

      Explore Healio.com Ophthalmology
      Congenital Hypertrophy of the Retinal Pigment Epithelium: Choroidal Cavitation Demonstrated on Spectral-Domain OCT

      A patient with solitary congenital hypertrophy of the retinal pigment epithelium demonstrated a striking choroidal cavitation on spectral-domain optical coherence tomography (OCT). Although photoreceptor atrophy overlying congenital hypertrophy of the retinal pigment epithelium has been described on time-domain OCT, this patient manifested a previously unrecognized tomographic feature.

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    11. Multimodal Imaging of Optic Disc Drusen

      Explore American Journal of Ophthalmology Ophthalmology
      Multimodal Imaging of Optic Disc Drusen

      Purpose To evaluate optic disc drusen, extracellular protein deposits known to contain numerous aggregates of mitochondria, using multimodal modalities featuring optical coherence tomography (OCT) and autofluorescence imaging. Design Retrospective observational case series. Methods Eyes with optic nerve drusen were examined with enhanced depth imaging (EDI)-OCT, swept source OCT, and fundus autofluorescence using a fundus camera. Results Twenty-six eyes of 15 patients with optic disc drusen were evaluated. EDI-OCT and swept source OCT showed multiple optic disc drusen at different levels; most were located immediately anterior to the lamina cribrosa. The drusen were ovoid regions of lower reflectivity that were ...

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      Mentions: Richard F. Spaide

    12. Visible-light optical coherence tomography for retinal oximetry

      Explore opticsinfobase.org
      Visible-light optical coherence tomography for retinal oximetry

      We applied a visible-light spectroscopic optical coherence tomography (vis-OCT) for in vivo retinal oximetry. To extract hemoglobin oxygen saturation (sO2) in individual retinal vessels, we established a comprehensive analytical model to describe optical absorption, optical scattering, and blood cell packing factor in the whole blood and fit the acquired vis-OCT signals from the bottom of each imaged vessel. We found that averaged sO2 values in arterial and venous bloods were 95% and 72%, respectively.

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      Mentions: Northwestern University Vadim Backman Ji Yi

    13. Single-shot speckle reduction and dispersion compensation in optical coherence tomography by compounding fractional Fourier domains

      Explore opticsinfobase.org
      Single-shot speckle reduction and dispersion compensation in optical coherence tomography by compounding fractional Fourier domains

      We present speckle suppression and dispersion compensation for Fourier-domain optical coherence tomography based on fractional Fourier transforms of a single A scan. A 1.54-fold reduction in speckle contrast was achieved with group velocity dispersion compensation. The method is demonstrated on biological samples using a swept source configuration at 1310 nm and a spectral-domain system at 840 nm

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      Mentions: University of Auckland Frederique Vanholsbeeck

    14. In situ optical coherence tomography of percutaneous implant-tissue interfaces in a murine model

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      In situ optical coherence tomography of percutaneous implant-tissue interfaces in a murine model

      Novel surface coatings of percutaneous implants need to be tested in biocompatibility studies. The use of animal models for testing usually involves numerous lethal biopsies for the analysis of the implant-tissue interface. In this study, optical coherence tomography (OCT) was used to monitor the reaction of the skin to a percutaneous implant in an animal model of hairless but immunocompetent mice. In vivo optical biopsies with OCT were taken at days 7 and 21 after implantation and post mortem on the day of noticeable inflammation. A Fourier-domain OCT was programmed for spoke pattern scanning schemes centered at the implant midpoint ...

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      Mentions: Alexander Krüger University of Hannover Laser Zentrum Hannover

    15. NinePoint Medical launches esophageal imaging system

      Explore bizjournals Funding
      NinePoint Medical launches esophageal imaging system

      Cambridge medical device company NinePoint Medical Inc. on Thursday launched its lead product in the U.S., an imaging system that makes it easier to examine and detect diseases of the esophagus. NinePoint’s proprietary NvisionVLE Imaging System was granted 510(k) clearance in December 2011 to be used as an imaging tool in the evaluation of human tissue microstructure. Last month, it received additional clearance to to include imaging of esophageal tissue microstructure. In June 2012, the device received European CE mark approval .

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      Mentions: Massachusetts General Hospital NinePoint Medical
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    Accurate prediction of collapse temperature using optical coherence tomography-based freeze-drying microscopy Visualisation of a coronary stent presenting late mechanical failure in an aberrant left circumflex artery with coronary computed tomography angiography and optical coherence tomography St. Jude Medical Announces European Approval of 3-D Vessel Reconstruction Technology to Aid Physicians in Stent Placement Inter-Scan Reproducibility of Geometric Coronary Artery Measurements Using Frequency-Domain Optical Coherence Tomography Interest of High Definition Optical Coherent Tomography (HD‐OCT) for imaging of melanoma Full-Field Thickness Distribution of Human Tympanic Membrane Obtained with Optical Coherence Tomography NinePoint Medical Announces U.S. Commercial Availability of the NvisionVLE™ Imaging System OCT imaging market led by Carl Zeiss and St. Jude Medical Noninvasive three-dimensional live imaging methodology for the spindles at meiosis and mitosis Automated non-rigid registration and mosaicing for robust imaging of distinct retinal capillary beds using speckle variance optical coherence tomography Intravascular optical coherence tomography imaging at 3200 frames per second Frequency multiplexed long range swept source optical coherence tomography

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  13. Recent Quotes

    1. OCT technology has become increasingly important to help diagnose and treat patients with coronary artery disease. The ILUMIEN OPTIS system is a significant advancement in intravascular imaging technology allowing physicians to comprehensively assess more vessel in less time and more easily plan their PCI procedure. The three-dimensional format of the ILUMIEN OPTIS system provides a more true-to-life perspective of the arteries, which allows for individual decision making and precise guidance of stent placement to optimize coronary interventions.
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    2. The advancements in the ILUMIEN OPTIS system reflect the commitment by St. Jude Medical to provide innovative products that reduce health care costs and improve outcomes for patients who suffer from coronary artery disease...This next-generation system delivers critical information to physicians about the location and severity of disease within the coronary arteries, potentially resulting in better medical decision-making and overall cost-effective treatment.
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    3. For NinePoint, the launch of our NvisionVLE Imaging System is the culmination of many major milestones over the past few years, and a great testament to the hard work of our team...It is always a great feeling to release a new medical device and make it available for improving patient care. As the only volumetric, optical coherence tomography (OCT) device for endoscopic and esophageal tissue imaging commercially available in the U.S., the introduction of the NvisionVLE Imaging System represents a significant addition to the current imaging landscape. We are pleased to offer clinicians across the country a new approach to evaluate esophageal tissue microstructure with faster imaging speed and improved image resolution, potentially leading to better biopsy targeting, reduced costs and improved patient outcomes.
      By Charles Carignan
    4. Our widespread presence in various business fields and regions enables us to even out any fluctuations in business and to continue our long-term growth trend.
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    5. We anticipate revenue of between € 880 and 910 million.
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    6. The progression to 1 um extreme resolution imaging is an exciting advancement for our Envisu R-Class research product line...The importance of this innovation is that it offers researchers true cellular-level in vivo optical histology. This Extreme High Resolution (XHR) capability is unlocked only by the combination of Bioptigen’s patented spectrometer and signal processing technologies with the NKT Photonics SuperK supercontinuum source.
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    7. The progression to 1 µm extreme resolution imaging is an exciting advancement for our Envisu R-Class research product line
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    8. NKT Photonics is delighted to collaborate with Bioptigen to demonstrate the capability of our SuperK EXTREME fiber lasers integrated into high performance OCT systems
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    9. The OCT technology provided by the RTVue and iVue combined with the functional testing from the Octopus will be the best of both worlds, offering the optimum structure-function solution.
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    10. The NvisionVLE Imaging System is the first and only volumetric, optical coherence tomography device cleared by the FDA for endoscopic imaging, and now imaging of esophageal tissue microstructure...Expanded FDA 510(k) clearance for imaging of the esophagus represents an important milestone as we progress toward commercializing the NvisionVLE Imaging System this year. We believe that the NvisionVLE Imaging System will allow physicians to see more esophageal tissue for biopsy and treatment procedures, providing them with valuable imaging information.
      By Charles Carignan