1. Featured Articles

    1. Characterization and quantification of necrotic tissues and morphology in multicellular ovarian cancer tumor spheroids using optical coherence tomography

      Explore OSA | OSA Publishing Oncology
      Characterization and quantification of necrotic tissues and morphology in multicellular ovarian cancer tumor spheroids using optical coherence tomography

      The three-dimensional (3D) tumor spheroid model is a critical tool for high-throughput ovarian cancer research and anticancer drug development in vitro . However, the 3D structure prevents high-resolution imaging of the inner side of the spheroids. We aim to visualize and characterize 3D morphological and physiological information of the contact multicellular ovarian tumor spheroids growing over time. We intend to further evaluate the distinctive evolutions of the tumor spheroid and necrotic tissue volumes in different cell numbers and determine the most appropriate mathematical model for fitting the growth of tumor spheroids and necrotic tissues. A label-free and noninvasive swept-source optical coherence ...

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    2. Optical Coherence Tomography for Neurovascular Disorders

      Explore ScienceDirect Cardiology , Neurology
      Optical Coherence Tomography for Neurovascular Disorders

      Diagnosis of cerebrovascular disease includes vascular neuroimaging techniques such as CT angiography, MR angiography (with or without use of contrast agents) and catheter digital subtraction angiography. These techniques provide mostly information about the vessel lumen. Vessel wall imaging with MR seeks to characterize cerebrovascular pathology, but with resolution that is often insufficient for small lesions. Intravascular imaging techniques such as ultrasound and optical coherence tomography (OCT), used for over a decade in the peripheral circulation, is not amendable to routine deployment in the intracranial circulation due to vessel caliber and tortuosity. However, advances in OCT technology including the probe profile ...

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      Mentions: Gentuity

    3. Three dimensional reconstruction of coronary artery stents from optical coherence tomography: experimental validation and clinical feasibility

      Explore Nature Publishing Group Cardiology
      Three dimensional reconstruction of coronary artery stents from optical coherence tomography: experimental validation and clinical feasibility

      The structural morphology of coronary stents (e.g. stent expansion, lumen scaffolding, strut apposition, tissue protrusion, side branch jailing, strut fracture), and the local hemodynamic environment after stent deployment are key determinants of procedural success and subsequent clinical outcomes. High-resolution intracoronary imaging has the potential to enable the geometrically accurate three-dimensional (3D) reconstruction of coronary stents. The aim of this work was to present a novel algorithm for 3D stent reconstruction of coronary artery stents based on optical coherence tomography (OCT) and angiography, and test experimentally its accuracy, reproducibility, clinical feasibility, and ability to perform computational fluid dynamics (CFD) studies ...

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      Mentions: Massachusetts Institute of Technology Emory University Mount Sinai School of Medicine

    4. Volumetric growth tracking of patient-derived cancer organoids using optical coherence tomography

      Explore OSA | OSA Publishing Oncology
      Volumetric growth tracking of patient-derived cancer organoids using optical coherence tomography

      Patient-derived cancer organoids (PCOs) are in vitro organotypic models that reflect in vivo drug response, thus PCOs are an accessible model for cancer drug screening in a clinically relevant timeframe. However, current methods to assess the response of PCOs are limited. Here, a custom swept-source optical coherence tomography (OCT) system was used to rapidly evaluate volumetric growth and drug response in PCOs. This system was optimized for an inverted imaging geometry to enable high-throughput imaging of PCOs. An automated image analysis framework was developed to perform 3D single-organoid tracking of PCOs across multiple time points over 48 hours. Metabolic inhibitors ...

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      Mentions: University of Wisconsin

    5. Postdoctoral Research Associate – Optical Coherence Tomography at the University of Wisconsin-Madison

      Explore Optical Coherence Tomography News Jobs & Studentships
      Postdoctoral Research Associate – Optical Coherence Tomography at the University of Wisconsin-Madison

      The Organization As an independent research organization, the Morgridge Institute for Research explores uncharted scientific territory to discover tomorrow’s cures. In affiliation with the University of Wisconsin-Madison, we support researchers who take a fearless approach to advancing human health in emerging fields such as regenerative biology, metabolism, virology and medical engineering. Through public programming, we work to inspire scientific curiosity in everyday life. The Opportunity Applications are invited for a Postdoctoral Researcher at the Morgridge Institute for Research and the University of Wisconsin, Madison. The objective of this research project is to develop and apply photothermal optical coherence tomography ...

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      Mentions: University of Wisconsin

    6. Perimeter Medical Imaging AI Announces Important Milestone with Commercial-Scale Manufacturing of Perimeter S-Series OCT Now Underway

      Explore Investor Relations Cardiology , Other Business News
      Perimeter Medical Imaging AI Announces Important Milestone with Commercial-Scale Manufacturing of Perimeter S-Series OCT Now Underway

      Perimeter Medical Imaging AI, Inc. , a medical technology company driven to transform cancer surgery with ultra-high-resolution, real-time, advanced imaging tools to address high unmet medical needs, today announced that it has successfully completed the technology transfer of its manufacturing process for the production of its optical coherence tomography (OCT) imaging systems with Minnetronix Medical, a leading medical technology and operations partner to global medical device companies. \ Commercial-scale manufacturing of Perimeter S-Series OCT now underway (Photo: Business Wire) Jeremy Sobotta, Perimeter’s Chief Executive Officer stated, “The completed technology transfer marks a significant achievement for Perimeter. For the first time, the ...

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      Mentions: Perimeter Medical Imaging

    7. Research Associate in Biophotonics at University of Sheffield

      Explore Optical Coherence Tomography News Jobs & Studentships
      Research Associate in Biophotonics at University of Sheffield

      University of Sheffield - Faculty of Engineering: Department of Electronic and Electrical Engineering Location: Sheffield Salary: £31,866 to £40,322 Grade 7 annum Hours: Full Time Contract Type: Fixed-Term/Contract Placed On: 20th May 2021 Closes: 16th June 2021 Job Ref: UOS028559 Contract Type: Fixed term until for 36 months. As a Research Associate, you will work in the biophotonics group of Professor Stephen Matcher. Steve Matcher’s group has a strong international reputation in biophotonics, especially in the development and application of optical coherence tomography (OCT) techniques. We maintain active collaborative links within the university (for example, the Medical ...

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      Mentions: University of Sheffield

    8. Postdoctoral Research Associate GlaxoSmithKline Center for Optical Molecular Imaging Beckman Institute for Advanced Science and Technology University of Illinois at Urbana-Champaign

      Explore Optical Coherence Tomography News Jobs & Studentships
      Postdoctoral Research Associate GlaxoSmithKline Center for Optical Molecular Imaging Beckman Institute for Advanced Science and Technology University of Illinois at Urbana-Champaign

      The GlaxoSmithKline Center for Optical Molecular Imaging at the Beckman Institute for Advanced Science and Technology seeks a bright, energetic, and motivated candidate to fill a vacancy for a full-time Postdoctoral Research Associate in the area of image data analysis. The purpose of this position is to lead the analysis of image data from translational optical biomedical imaging systems. The successful candidate will need a solid and broad understanding of image analysis software as well as software development including high-level user interface requirements in a Windows environment, data file structure design, experience with data acquisition and control interfacing, high-volume real-time ...

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      Mentions: University of Illinois at Urbana-Champaign

    9. Time-resolved spectral-domain optical coherence tomography with CMOS SPAD sensors

      Explore OSA | OSA Publishing
      Time-resolved spectral-domain optical coherence tomography with CMOS SPAD sensors

      We present a first spectral-domain optical coherence tomography (SD-OCT) system deploying a complementary metal-oxide-semiconductor (CMOS) single-photon avalanche diode (SPAD) based, time-resolved line sensor. The sensor with 1024 pixels achieves a sensitivity of 87 dB at an A-scan rate of 1 kHz using a supercontinuum laser source with a repetition rate of 20 MHz, 38 nm bandwidth, and 2 mW power at 850 nm centre wavelength. In the time-resolved mode of the sensor, the system combines low-coherence interferometry (LCI) and massively parallel time-resolved single-photon counting to control the detection of interference spectra on the single-photon level based on the time-of-arrival of ...

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      Mentions: Thorlabs Cambridge Technology Wasatch Photonics

    10. Notal Vision raises up to $60 million to support development of its Home OCT technology and commercial growth of its ForeseeHome AMD Monitoring Program

      Explore Optical Coherence Tomography News Ophthalmology , Funding , Other Business News
      Notal Vision raises up to $60 million to support development of its Home OCT technology and commercial growth of its ForeseeHome AMD Monitoring Program

      Notal Vision, Inc., a privately held ophthalmic home monitoring services provider focused on early disease detection and treatment monitoring is pleased to announce the closing of a Series D financing co-led by Soleus Capital and the company’s majority shareholder Ganot Capital. Existing shareholders Elron and Evergreen contributed significantly to the round. The investment supports the commercial growth of the company’s current service, the ForeseeHome AMD Monitoring Program, as well as the go-to-market strategy for its Home OCT pipeline technology. “We believe the Home OCT device from Notal Vision has the potential to transform care for millions of patients ...

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      Mentions: Notal Vision

    11. Tesseract Health Closes Oversubscribed $80 Million Series B Financing

      Explore Optical Coherence Tomography News Ophthalmology , Funding , Other Business News
      Tesseract Health Closes Oversubscribed $80 Million Series B Financing

      Tesseract HealthTM Inc. has raised $80 million in an oversubscribed Series B financing round -- with support from investors including Foresite Capital, Glenview Capital, and Opaleye -- to advance the development of the company’s groundbreaking Tesseract iC™ eye-imaging diagnostic technology platform. The funds will be used to conduct research to advance the Tesseract iC platform, accelerate the company’s push to obtain US and international regulatory clearances, and ramp up manufacturing. The funds will also be used to further enhance Tesseract’s unique AI capabilities and prepare the company for commercial launch. The Tesseract iC platform (not yet cleared by the ...

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      Mentions: FDA Tesseract Health

    12. AI spots neurons better than human experts

      Explore EurekAlert! Ophthalmology
      AI spots neurons better than human experts

      A new combination of optical coherence tomography (OCT), adaptive optics and deep neural networks should enable better diagnosis and monitoring for neuron-damaging eye and brain diseases like glaucoma. Biomedical engineers at Duke University led a multi-institution consortium to develop the process, which easily and precisely tracks changes in the number and shape of retinal ganglion cells in the eye. This work appears in a paper published on May 3 in the journal Optica . The retina of the eye is an extension of the central nervous system. Ganglion cells are one of the primary neurons in the eye that process and ...

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      Mentions: University of Maryland Heidelberg Engineering Duke University
    13. See all articles

  2. Recent Articles From Around The Web

    1. The additional diagnostic value of optical coherence tomography in clinically diagnosed basal cell carcinomas undergoing direct surgical excision

      Explore Wiley Online Library Dermatology
      The additional diagnostic value of optical coherence tomography in clinically diagnosed basal cell carcinomas undergoing direct surgical excision

      Clinical examination appears to be very sensitive for diagnosing BCC (90%), but the specificity is reported to be low (28.6-48.9%).(1, 2) Additional use of dermoscopy can increase specificity to 54.3-55.6% compared to clinical examination alone.(1, 2) With use of optical coherence tomography (OCT), a non-invasive diagnostic method, in addition to clinical and dermoscopic examination, it is possible to further increase the specificity to 76% at a sensitivity of 95%.(1, 3, 4) These results apply to a population of patients with a clinical suspicion of BCC who had an indication for biopsy (e.g ...

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      Mentions: Academic Hospital Maastricht

    2. Stabilizing the phase of swept-source optical coherence tomography by a wrapped Gaussian mixture model

      Explore OSA | OSA Publishing
      Stabilizing the phase of swept-source optical coherence tomography by a wrapped Gaussian mixture model

      The phase of an optical coherence tomography (OCT) signal carries critical information about particle micro-displacements. However, swept-source OCT (SSOCT) suffers from phase instability problems due to trigger jitters from the swept source. In this Letter, a wrapped Gaussian mixture model (WGMM) is proposed to stabilize the phase of SSOCT systems. A closed-form iteration solution of the WGMM is derived using the expectation-maximization algorithm. Necessary approximations are made for real-time graphic processing unit implementation. The performance of the proposed method is demonstrated through ex vivo, in vivo, and flow phantom experiments. The results show the robustness of the method in different ...

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      Mentions: Johns Hopkins University

    3. Unsaturated fatty acid salts remove biofilms on dentures

      Explore Nature Publishing Group Dentistry
      Unsaturated fatty acid salts remove biofilms on dentures

      Candidiasis-causing Candida sp. forms biofilms with various oral bacteria in the dentures of the elderly, making it harder to kill and remove the microorganism due to the extracellular polymeric substances. We found that biofilms on dentures can effectively be removed by immersion in an unsaturated fatty acid salt solution. Using optical coherence tomography to observe the progression of biofilm removal by the fatty acid salt solution, we were able to determine that the removal was accompanied by the production of gaps at the interface between the biofilm and denture resin. Furthermore, microstructural electron microscopy observations and time-of-flight secondary ion mass ...

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    4. Repeatability and inter-observer variation of choroidal thickness measurements using swept-source optical coherence tomography in myopic danish children aged 6–14 years

      Explore Wiley Online Library Ophthalmology
      Repeatability and inter-observer variation of choroidal thickness measurements using swept-source optical coherence tomography in myopic danish children aged 6–14 years

      Purpose: To estimate repeatability and inter-observer variation of choroidal thickness measurements in myopic Danish children aged 7-14 years using swept-source optical coherence tomography (SS-OCT). Methods: Thirty-nine children were enrolled. Optical correction was single-vision spectacles (SVS) or orthokeratology lenses (OKL). Three repeated 7 × 7 mm 3-dimensional SS-OCT macula scans and three repeated 9 mm SS-OCT line scans were collected for each child using a DRI OCT Triton. Choroidal thickness was measured using three different methods: line scan method 1 (LM1), line scan method 2 (LM2) and 3D macula scan method (3DM). Segmentation was adjusted if needed. Coefficients of repeatability (CR) and ...

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    5. Duke University Receives NIH Grant for Intraoperative OCT Guidance of Intraocular Surgery.

      Explore Optical Coherence Tomography News Ophthalmology , Funding
      Duke University Receives NIH Grant for Intraoperative OCT Guidance of Intraocular Surgery.

      Duke University Receives a 2021 NIH Grant for $743,426 for Intraoperative OCT Guidance of Intraocular Surgery. The principal investigator is Joseph Izatt. Below is a summary of the proposed work. This is a resubmission application for a Bioengineering Research Partnership (BRP) which brings together a highly collaborative and experienced team of engineers and ophthalmic surgeons to advance the state of the art in image-guided surgical interventions. We seek to overcome limitations to the surgeon’s current stereo microscopic view of ocular structures by continuing to integrate optical coherence tomography (OCT) technology, which is already well accepted in ophthalmic practice ...

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      Mentions: National Institutes of Health Duke University

    6. Case Western Reserve University Receives NIH Grant for Noninvasive Assessment of the Cornea by Diffusion OCT

      Explore Optical Coherence Tomography News Ophthalmology , Funding
      Case Western Reserve University Receives NIH Grant for Noninvasive Assessment of the Cornea by Diffusion OCT

      Case Western Reserve University Receives a 2021 NIH Grant for $381,543 for Noninvasive Assessment of the Cornea by Diffusion OCT. The principal investigator is Andrew Rollins Below is a summary of the proposed work. Keratoconus is a degenerative disease of the cornea that is a major cause of reduced vision-related quality of life in the United States, often leading to corneal transplantation. Ectasia after refractive surgery is a vision-threatening complication that can occur in apparently low-risk patients despite current screening technology. The biomechanical properties of the cornea play a central role in these diseases, but diagnostics are still rooted ...

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      Mentions: National Institutes of Health Case Western Reserve University

    7. Stevens Institute of Technology Receives NIH Grant for In Vivo Imaging Platform for Ectopic Pregnancy Research in Mouse Models

      Explore Optical Coherence Tomography News Gynecology , Funding
      Stevens Institute of Technology Receives NIH Grant for In Vivo Imaging Platform for Ectopic Pregnancy Research in Mouse Models

      Stevens Institute of Technology Receives a 2021 NIH Grant for $182,953 for In Vivo Imaging Platform for Ectopic Pregnancy Research in Mouse Models. The principal investigator is Shang Wang. Below is a summary of the proposed work. Tubal ectopic pregnancy (tEP) is a life-threatening reproductive disorder affecting nearly 2% of pregnancies in developed countries. The etiology of tEP is far from resolved, leaving no way to design preventive measures and few strategies for early diagnosis. Investigating how a tEP forms and develops has been extremely difficult. Because it is unethical to access human oviduct (fallopian tube) during healthy pregnancies ...

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      Mentions: National Institutes of Health

    8. Massachusetts Institute of Technology Receives NIH Grant for Novel Optical Diagnostics with Optical Coherence Tomography

      Explore Optical Coherence Tomography News Funding
      Massachusetts Institute of Technology Receives NIH Grant for Novel Optical Diagnostics with Optical Coherence Tomography

      Massachusetts Institute of Technology Receives a 2021 NIH Grant for $436,277 for Novel Optical Diagnostics with Optical Coherence Tomography. The principal investigator is James Fujimoto. Below is a summary of the proposed work. This proposal is a renewal of an ongoing collaborative program among investigators at the Massachusetts Institute of Technology (MIT) and New England Eye Center (NEEC). The program focuses on the development of optical coherence tomography (OCT) technology and its application to investigate structural alterations and blood flow impairment in age-related macular degeneration (AMD). Aim 1. Next Generation OCT Technology for Imaging Structure and Blood Flow in ...

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      Mentions: Massachusetts Institute of Technology National Institutes of Health

    9. Case Western University Receives NIH Grant for Computer Assisted Coronary Artery Stent Interventions

      Explore Optical Coherence Tomography News Cardiology , Funding
      Case Western University Receives NIH Grant for Computer Assisted Coronary Artery Stent Interventions

      Case Western University Receives a 2021 NIH Grant for $484,748 for Computer Assisted Coronary Artery Stent Interventions. The principal investigator is David Wilson. Below is a summary of the proposed work Computer assisted coronary artery stent interventions Summary When treating highly calcified coronary artery lesions with stents, interventional cardiologists, with limited information, make stressful treatment decisions, which can lead to inadequate stent deployment and poor outcomes, or even rare calamitous events. When calcification is present, a cardiologist must choose to use a normal sized angioplasty balloon; a larger angioplasty balloon with increasingly high, prolonged pressures to fracture the calcification ...

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      Mentions: National Institutes of Health Case Western Reserve University

    10. Methods and system for imaging an inner limiting membrane using a stain

      Explore uspto.gov Ophthalmology , Patents
      Methods and system for imaging an inner limiting membrane using a stain

      Systems and methods for imaging tissue are described. Particularly, systems and methods of imaging an inner limiting membrane, epi-retinal membrane, or posterior vitreous cortex of a patient's eye are disclosed. Imaging an inner limiting membrane, epi-retinal membrane, or posterior vitreous cortex may include applying a stain to the inner limiting membrane, epi-retinal membrane, or posterior vitreous cortex of the patient's eye, causing the stain to produce fluorescent light having a wavelength within a near-infrared range, capturing the fluorescent light, and producing an Optical Coherence Tomography (OCT) image of the inner limiting membrane, epi-retinal membrane, or posterior vitreous cortex ...

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    11. Micro-molded anamorphic reflector lens for image guided therapeutic/diagnostic catheters

      Explore uspto.gov Patents , Probes
      Micro-molded anamorphic reflector lens for image guided therapeutic/diagnostic catheters

      A catheter system for optical coherence tomography includes an elongate catheter body, an optical fiber in the elongate catheter body, and an anamorphic lens assembly coupled with a distal end of the optical fiber. The optical fiber and the lens assembly are together configured to provide a common path for optical radiation reflected from a target and from a reference interface between the distal end of the optical fiber and the lens assembly.

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      Mentions: Avinger

    12. Single-ended probing through a multimode fiber having distributed reflectors

      Explore uspto.gov Funding
      Single-ended probing through a multimode fiber having distributed reflectors

      An optical frequency-domain reflectometer (OFDR) capable of estimating the transfer matrix of a multimode optical fiber using mode-selective measurements performed from a single end of the fiber. In an example embodiment, the multimode optical fiber includes distributed reflectors designed to generate relatively strong light reflections along the length of the fiber at a desired spatial resolution.

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    13. Higher-Order Core-Like Modes in Double-Clad Fiber Contribute to Multipath Artifacts in Optical Coherence Tomography

      Explore IEEE Xplore
      Higher-Order Core-Like Modes in Double-Clad Fiber Contribute to Multipath Artifacts in Optical Coherence Tomography

      Double-clad fiber (DCF) has enabled the combination of endoscopic optical coherence tomography (OCT) with secondary optical modalities. While DCF offers an additional optical channel, it is widely understood that its use reduces the quality of OCT owing to the introduction of multipath artifacts. We show here that an unexpected higher-order mode (HOM) with its energy confined to the DCF core can contribute to these artifacts. The existence of this HOM is confirmed using the spatially and spectrally (S2) resolved imaging method. The group delay difference of the HOM is shown to be consistent with the delay of the diffuse ghost ...

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    14. Structural changes of corneal epithelium in belantamab-associated superficial keratopathy using anterior segment optical coherence tomography

      Explore ScienceDirect Ophthalmology
      Structural changes of corneal epithelium in belantamab-associated superficial keratopathy using anterior segment optical coherence tomography

      Purpose To describe structural changes in corneal epithelium using anterior segment optical coherence tomography (AS-OCT) in two relapsed and refractory multiple myeloma (RRMM) patients with bilateral belantamab-associated superficial keratopathy (BASK). Observations: case 1 A 56-year-old male who was diagnosed with RRMM and initiated on belantamab mafodotin, presented on day 42 (three weeks after the second infusion) with decreased pinhole visual acuity from 20/20 and 20/25 to 20/70 and 20/50 in the right eye and left eye, respectively. Slit-lamp examination revealed moderate superficial keratopathy with microcystic-like epithelial changes (MECs) in the paracentral cornea in both eyes. AS-OCT ...

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      Mentions: Stanford University Kobe University Graduate School of Medicine

    15. Automated identification of SD-optical coherence tomography derived macular diseases by combining 3D-block-matching and deep learning techniques

      Explore Taylor & Francis Online Ophthalmology
      Automated identification of SD-optical coherence tomography derived macular diseases by combining 3D-block-matching and deep learning techniques

      This paper reveals an automatic approach for macular diagnostic by the use of Optical Coherence Tomography (OCT) in the evaluation process. At preliminary behaviour levels, the evaluation of macular zone in OCT scan is characterised by an error prone task, related to the experience and the attention of ophthalmologists. Thus, different techniques of OCT-image analysis help the option of obtaining a consistent and independent diagnosis to identify macular degeneration behaviour. In this work, we report an automated approach based on a combined filtering and classification strategy. The presented method is validated on a real integrated diabetic oedema macular (DME) and ...

      Read Full Article
      16. See all articles
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  6. Organizations in the News

    1. (5 articles) National Institutes of Health
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  8. Picture Gallery

    Characterization and quantification of necrotic tissues and morphology in multicellular ovarian cancer tumor spheroids using optical coherence tomography Optical Coherence Tomography for Neurovascular Disorders Three dimensional reconstruction of coronary artery stents from optical coherence tomography: experimental validation and clinical feasibility Volumetric growth tracking of patient-derived cancer organoids using optical coherence tomography Postdoctoral Research Associate – Optical Coherence Tomography at the University of Wisconsin-Madison Perimeter Medical Imaging AI Announces Important Milestone with Commercial-Scale Manufacturing of Perimeter S-Series OCT Now Underway Research Associate in Biophotonics at University of Sheffield Postdoctoral Research Associate GlaxoSmithKline Center for Optical Molecular Imaging Beckman Institute for Advanced Science and Technology University of Illinois at Urbana-Champaign Time-resolved spectral-domain optical coherence tomography with CMOS SPAD sensors Notal Vision raises up to $60 million to support development of its Home OCT technology and commercial growth of its ForeseeHome AMD Monitoring Program Tesseract Health Closes Oversubscribed $80 Million Series B Financing AI spots neurons better than human experts

  9. Popular Articles This Week

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  11. Recent Quotes

    1. “I am inspired by Dr. Sanford Greenberg’s vision to end blindness and humbled to be recognized along with Prof. Jim Fujimoto and Eric Swanson for the development of optical coherence tomography, a very sensitive imaging technology widely used to detect and diagnose eye diseases...At the Casey Eye Institute, we are continuing to work on ending all preventable blindness by advancing diagnostic technologies, broadening community outreach, and providing cutting edge treatments.
      By David Huang
    2. We will develop a novel method for the imaging and assessment of corneal elastic properties that could potentially be used for routine clinical diagnostics of different corneal diseases and treatment.
      By Kirill V. Larin
    3. The Board, founders, and team at SpectraWAVE have been an inspiring group to join. They are talented, experienced, and purpose-driven, which will be key as we move towards the launch of our new photonic imaging technology for coronary artery disease. Our flagship technology will define our clinical impact and growth, and we are working hard to bring that solution to the market to help as many patients as possible with coronary artery disease.
      By Eman Namati
    4. After planning a procedure with angiography alone, we exposed physicians to all the information provided by OCT on the same blockage and were able to demonstrate the significant impact that the information had on our decisions...OCT takes the guesswork out of angiography, offering doctors real-time high-quality granularity and precision when performing PCIs, and helping doctors make real-time decisions in the cath lab.
      By Hiram G. Bezerra
    5. Previous research has seen a thinning of the retina in Alzheimer's patients, but by adding a light-scattering technique to the measurement, we've found that the retinal nerve fiber layer is also rougher and more disordered...Our hope is that we can use this insight to create an easy and cheap screening device that wouldn't only be available at your doctor's office, but at places like your local pharmacy as well
      By Adam Wax
    6. Despite living in the 'digital age,' surgeons must routinely rely on their eyesight and sense of touch to determine if they have removed the entire tumor during breast-conserving surgery...Due to lack of adequate tools, 20 to 30 percent of patients must return for additional surgery, resulting in substantial physical and financial burdens and increased risk of complications.
      By Brendan F. Kennedy
    7. In ophthalmology we have a wealth of eye images—fundus photographs, optical coherence tomography (OCT), etc.—that are fundamental to the diagnosis, monitoring, and treatment of a number of eye diseases, so this field is ideally suited for deep learning applications.
      By Felipe A. Medeiros
    8. We are delighted to have received MHLW approval of the Novasight Hybrid system. Clinical data in the past several years has increasingly demonstrated that intravascular imaging with either IVUS or OCT has significant potential to improve outcomes in the large number of patients being treated with angioplasty and stenting for coronary artery disease. However, there are substantial differences between the images generated by these two technologies. Until now, physicians in Japan have had to choose between IVUS or OCT when performing percutaneous coronary interventions (PCI). We are delighted that Conavi and Japan Lifeline can now begin to offer both of these highly complementary imaging techniques on a single catheter to physicians in Japan.
      By Brian K. Courtney
    9. It is such a huge honor to be recognized with this prestigious industry award for best healthcare product in 2020, and we’d like to thank SPIE and Photonics Media for sponsoring this incredible opportunity...Our team is working hard to provide better options to millions of patients who suffer from middle ear infections. Following our recent 510(k) clearance from the FDA, we cannot wait to see how the TOMi Scope impacts the standard of care for this incredibly common disease.
      By Ryan L. Shelton
    10. We developed an algorithm that can be used to automatically analyze optical coherence tomography (OCT) images of the retina to predict whether a patient is likely to respond to anti-VEGF treatments...This research represents a step toward precision medicine, in which such predictions help clinicians better select first-line therapies for patients based on specific disease conditions.
      By Sina Farsiu