1. Feature Of The Week

    The study of mosquitoes and analysis of their behavior are of crucial importance in the on-going efforts to control the alarming increase in mosquito-borne diseases. Furthermore, a non-destructive and real-time imaging technique to study the anatomical features of mosquito specimens can greatly aid the study of mosquitoes. In this study, we demonstrate the three-dimensional imaging capabilities of optical coherence tomography (OCT) for structural analysis of Anopheles sinensis mosquitoes. The anatomical features of An. sinensis head, thorax, and abdominal regions, along with the morphology of internal structures, such as foregut, midgut, and hindgut, were studied using OCT imaging. Two-dimensional and three-dimensional OCT images, used in conjunction with histological images, proved useful for anatomical analysis of mosquito specimens. By presenting this work as an initial study, we demonstrate the applicability of OCT for future mosquito-related entomological research, and also in identifying changes in mosquito anatomical structure.

    For more information see recent Article. Courtesy Naresh Kumar Ravichandran from Kyungpook National University. To share this article click Here.

  2. Featured Articles

    1. The Validity of the Diagnosis of Plant Leaf Infections Using Non-Destructive Optical Inspection Technique and Depth-Scan Signal Analysis

      Explore ripublication.com NDE/NDT , Other Non-Medical
      The Validity of the Diagnosis of Plant Leaf Infections Using Non-Destructive Optical Inspection Technique and Depth-Scan Signal Analysis

      The applicability of non-destructive optical imaging technique for the diagnosis of infected leaf materials was investigated along with a depth-scan (amplitude depth profile) signal analysis. The experimented plant leaf specimens were collected from persimmon plantations and the specimens were categorized into three groups: healthy leaf specimens, infected leaf specimens, and apparently healthy leaf specimens collected from infected trees. The non-destructive diagnosis was performed using 840 nm spectral domain optical coherence tomography (SD-OCT) system. The obtained OCT results confirmed that the proposed method is capable of identifying morphological differences between healthy specimens from infected specimens and partially infected specimens. Therefore, this ...

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      Mentions: Jeehyun Kim Kyungpook National University Ruchire Eranga Wijesinghe

    2. Optical coherence tomography angiography retinal vascular network assessment in multiple sclerosis

      Explore SAGE Journals Neurology , Ophthalmology
      Optical coherence tomography angiography retinal vascular network assessment in multiple sclerosis

      Background: Optical coherence tomography (OCT) angiography is a new method to assess the density of the vascular networks. Vascular abnormalities are considered involved in multiple sclerosis (MS) pathology. Objective: To assess the presence of vascular abnormalities in MS and to evaluate their correlation to disease features. Methods: A total of 50 MS patients with and without history of optic neuritis (ON) and 46 healthy subjects were included. All underwent spectral domain (SD)-OCT and OCT angiography. Clinical history, Expanded Disability Status Scale (EDSS), Multiple Sclerosis Severity Score (MSSS) and disease duration were collected. Results: Angio-OCT showed a vessel density reduction ...

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    3. CNNs Enable Accurate and Fast Segmentation of Drusen in Optical Coherence Tomography

      Explore Home - Springer Ophthalmology
      CNNs Enable Accurate and Fast Segmentation of Drusen in Optical Coherence Tomography

      Optical coherence tomography (OCT) is used to diagnose and track progression of age-related macular degeneration (AMD). Drusen, which appear as bumps between Bruch’s membrane (BM) and the retinal pigment epithelium (RPE) layer, are among the most important biomarkers for staging AMD. In this work, we develop and compare three automated methods for Drusen segmentation based on the U-Net convolutional neural network architecture. By cross-validating on more than 50, 000 annotated images, we demonstrate that all three approaches achieve much better accuracy than a current state-of-the-art method. Highest accuracy is achieved when the CNN is trained to segment the BM ...

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      Mentions: University of Bonn Frank G. Holz

    4. Tissue characterization with depth-resolved attenuation coefficient and backscatter term in intravascular optical coherence tomography images

      Explore SPIE Digital Library Cardiology
      Tissue characterization with depth-resolved attenuation coefficient and backscatter term in intravascular optical coherence tomography images

      An important application of intravascular optical coherence tomography (IVOCT) for atherosclerotic tissue analysis is using it to estimate attenuation and backscatter coefficients. This work aims at exploring the potential of the attenuation coefficient, a proposed backscatter term, and image intensities in distinguishing different atherosclerotic tissue types with a robust implementation of depth-resolved (DR) approach. Therefore, the DR model is introduced to estimate the attenuation coefficient and further extended to estimate the backscatter-related term in IVOCT images, such that values can be estimated per pixel without predefining any delineation for the estimation. In order to exclude noisy regions with a weak ...

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      Mentions: Leiden University Academic Medical Center at the University of Amsterdam Patrick W. Serruys

    5. Performance characteristics of optical coherence tomography in assessment of Barrett's esophagus and esophageal cancer: systematic review

      Explore Journals Gastroenterology
      Performance characteristics of optical coherence tomography in assessment of Barrett's esophagus and esophageal cancer: systematic review

      Optical coherence tomography (OCT) can generate high-resolution images of the esophagus that allows cross-sectional visualization of esophageal wall layers. We conducted a systematic review to assess the utility of OCT for diagnosing of esophageal intestinal metaplasia (IM; Barrett's esophagus BE)), dysplasia, cancer and staging of early esophageal cancer. English language human observational studies and clinical trials published in PubMed and Embase were included if they assessed any of the following: (i) in-vivo features and accuracy of OCT at diagnosing esophageal IM, sub-squamous intestinal metaplasia (SSIM), dysplasia, or cancer, and (ii) accuracy of OCT in staging esophageal cancer. Twenty-one of ...

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    6. Serial 5-Year Evaluation of Side Branches Jailed by Bioresorbable Vascular Scaffolds Using 3-Dimensional Optical Coherence Tomography

      Explore Circulation Cardiology
      Serial 5-Year Evaluation of Side Branches Jailed by Bioresorbable Vascular Scaffolds Using 3-Dimensional Optical Coherence Tomography

      Background— The long-term fate of Absorb bioresorbable vascular scaffold (Abbott Vascular, Santa Clara, CA) struts jailing side branch ostia has not been clarified. We therefore evaluate serially (post-procedure and at 6 months, 1, 2, 3, and 5 years) the appearance and fate of jailed Absorb bioresorbable vascular scaffold struts. Methods and Results— We performed 3-dimensional optical coherence tomographic analysis of the ABSORB Cohort B trial (A Clinical Evaluation of the Bioabsorbable Everolimus Eluting Coronary Stent System in the Treatment of Patients With De Novo Native Coronary Artery Lesions) up to 5 years using a novel, validated cut-plane analysis method. We ...

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      Mentions: Patrick W. Serruys Stephan Windecker Yoshinobu Onuma

    7. Dual-beam manually-actuated distortion-corrected imaging (DMDI) with micromotor catheters

      Explore OSA | OSA Publishing
      Dual-beam manually-actuated distortion-corrected imaging (DMDI) with micromotor catheters

      e present a new paradigm for performing two-dimensional scanning called dual-beam manually-actuated distortion-corrected imaging (DMDI). DMDI operates by imaging the same object with two spatially-separated beams that are being mechanically scanned rapidly in one dimension with slower manual actuation along a second dimension. Registration of common features between the two imaging channels allows remapping of the images to correct for distortions due to manual actuation. We demonstrate DMDI using a 4.7 mm OD rotationally scanning dual-beam micromotor catheter (DBMC). The DBMC requires a simple, one-time calibration of the beam paths by imaging a patterned phantom. DMDI allows for distortion ...

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      Mentions: British Columbia Cancer Agency

    8. Rapid measurement of transversal flow velocity vector with high spatial resolution using speckle decorrelation optical coherence tomography

      Explore OSA | OSA Publishing
      Rapid measurement of transversal flow velocity vector with high spatial resolution using speckle decorrelation optical coherence tomography

      We propose and demonstrate a novel method that uses only three sets of B-scans to accurately determine both the direction and the speed of a transversal flow using speckle decorrelation optical coherence tomography. Our tri-scan method has the advantages of high measurement speed, high spatial resolution, and insensitivity to the flow speed. By introducing error maps, we show that the flow angle inaccuracy can be minimized by choosing the measurement result with a lesser error between results obtained from the

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      Mentions: Yimin Wang General Photonics Steve Yao

    9. Evaluating biomechanical properties of murine embryos using Brillouin microscopy and optical coherence tomography

      Explore SPIE Digital Library Developmental Biology
      Evaluating biomechanical properties of murine embryos using Brillouin microscopy and optical coherence tomography

      Embryogenesis is regulated by numerous changes in mechanical properties of the cellular microenvironment. Thus, studying embryonic mechanophysiology can provide a more thorough perspective of embryonic development, potentially improving early detection of congenital abnormalities as well as evaluating and developing therapeutic interventions. A number of methods and techniques have been used to study cellular biomechanical properties during embryogenesis. While some of these techniques are invasive or involve the use of external agents, others are compromised in terms of spatial and temporal resolutions. We propose the use of Brillouin microscopy in combination with optical coherence tomography (OCT) to measure stiffness as well ...

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      Mentions: University of Maryland Kirill V. Larin University of Houston

    10. Register Now for the International Congress on OCT Angiography, "en face" OCT, and Advances in OCT on December 15th in Rome Italy which Already has over 1,000 Attendees

      Explore Optical Coherence Tomography News
      Register Now for the International Congress on OCT Angiography, "en face" OCT, and Advances in OCT on December 15th in Rome Italy which Already has over 1,000 Attendees

      The fifth international congress on OCT Angiography, "en face" OCT, and advances in OCT will take place in Rome Italy on December 15th an 16th. The meeting has its own personality: it brings together both the clinical and basic science communities, has high scientific contents and good organization, friendly atmosphere, sweet weather and Rome beauty. The conference organizers include Bruno Lumbroso, David Huang, Gabriel Coscas, Yali Jia, K. Bailey Freund, Richard Rosen, Philip Rosenfeld, David Sarraf, Eric Souied, Richard Spaide, Giovanni Staurenghi, Nadia Waheed. Quan Dong Nguyen, SriniVas Sadda, Yves Cohen, Wolfgang Drexler, Joseph Carroll, and Ursula Schmidt Erfurth. The ...

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      Mentions: Philip J. Rosenfeld David Huang Wolfgang Drexler

    11. Automatic Identification of Weave Patterns of Checked and Colored Fabrics Using Optical Coherence Tomography

      Explore IEEE Xplore NDE/NDT
      Automatic Identification of Weave Patterns of Checked and Colored Fabrics Using Optical Coherence Tomography

      Identifying the weave pattern of fabrics can be done manually or automatically. Carrying out the weave recognition automatically will reduce the procedure time and error rates since automatic systems can perform successive measurements at high speeds and with great repeatability and quality. Woven fabric repeat identification systems that are automatic, usually work by employing complex algorithms and techniques. It is known that these automatic techniques struggle when trying to identify highly complex patterns, composing of a combination of different structures, figures, and colors. For example, image processing algorithms are known to make errors when dealing with checked and colored fabrics ...

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    12. Depolarization signatures map gold nanorods within biological tissue

      Explore lmrt.mit.edu
      Depolarization signatures map gold nanorods within biological tissue

      Owing to their electromagnetic properties, tunability and biocompatibility, gold nanorods are being investigated as multifunctional probes for a range of biomedical applications. However, detection beyond the reach of traditional fluorescence and two-photon approaches and quantitation of their concentration in biological tissue remain challenging tasks in microscopy. Here, we show how the size and aspect ratio that impart gold nanorods with their plasmonic properties also make them a source of entropy. We report on how depolarization can be exploited as a strategy to visualize gold nanorod diffusion and distribution in biologically relevant scenarios ex vivo, in vitro and in vivo. We ...

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      Mentions: Brett E. Bouma Massachusetts General Hospital Harvard University

    13. Thermo-elastic optical coherence tomography

      Explore OSA | OSA Publishing
      Thermo-elastic optical coherence tomography

      The absorption of nanosecond laser pulses induces rapid thermo-elastic deformation in tissue. A sub-micrometer scale displacement occurs within a few microseconds after the pulse arrival. In this Letter, we investigate the laser-induced thermo-elastic deformation using a 1.5 MHz phase-sensitive optical coherence tomography (OCT) system. A displacement image can be reconstructed, which enables a new modality of phase-sensitive OCT, called thermo-elastic OCT. An analysis of the results shows that the optical absorption is a dominating factor for the displacement. Thermo-elastic OCT is capable of visualizing inclusions that do not appear on the structural OCT image, providing additional tissue type information.

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      Mentions: Robert A. Huber Delft University of Technology Chinese Academy of Sciences

    14. Visualization and Detection of Ciliary Beating Pattern and Frequency in the Upper Airway using Phase Resolved Doppler Optical Coherence Tomography

      Explore Nature Publishing Group Pulmonology
      Visualization and Detection of Ciliary Beating Pattern and Frequency in the Upper Airway using Phase Resolved Doppler Optical Coherence Tomography

      Ciliary motion plays a critical role in the overall respiratory health of the upper airway. These cilia beat at a native frequency and in a synchronized pattern to continuously transport foreign particulate trapped in a layer of mucous out of the upper airway. Disruption of ciliary motion can lead to severe respiratory diseases and compromised respiratory function. Currently, the study of cilia requires expensive high speed cameras and high powered microscopes which is unsuitable for in vivo imaging and diagnosis. Doppler based optical coherence tomography has the potential to visualize the microscopic motion of cilia during their beating cycle. We ...

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      Mentions: Zhongping Chen UC Irvine Brian J. F. Wong

    15. Human Factor and Usability Testing of a Binocular Optical Coherence Tomography System

      Explore TVST Journal Ophthalmology
      Human Factor and Usability Testing of a Binocular Optical Coherence Tomography System

      Purpose : To perform usability testing of a binocular optical coherence tomography (OCT) prototype to predict its function in a clinical setting, and to identify any potential user errors, especially in an elderly and visually impaired population. Methods : Forty-five participants with chronic eye disease (mean age 62.7 years) and 15 healthy controls (mean age 53 years) underwent automated eye examination using the prototype. Examination included ‘whole-eye' OCT, ocular motility, visual acuity measurement, perimetry, and pupillometry. Interviews were conducted to assess the subjective appeal and ease of use for this cohort of first-time users. Results : All participants completed the full suite ...

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      Mentions: University College London University of Ulster Pearse A. Keane

    16. From lab to clinic

      Explore Physics Today
      From lab to clinic

      Last month I visited my eye doctor, Harold Jacobson, for a routine checkup. After reading rows of ever-smaller letters, just as I had when my eyes were first tested in the 1970s, I asked him what new technology he was most excited about. “Optical coherence tomography,” he replied. “It’s a game changer!” Jacobson had bought an OCT scanner after my previous visit, so I got to see the game changer firsthand. As a patient, I briefly looked into a pair of eyepieces. As an ophthalmologist, Jacobson reviewed a wealth of information on the scanner’s screen. Beside cross sections ...

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      Mentions: Carmen A. Puliafito James G. Fujimoto Carl Zeiss Meditec

    17. Optical coherence tomography detects necrotic regions and volumetrically quantifies multicellular tumor spheroids

      Explore Cancer Research Oncology
      Optical coherence tomography detects necrotic regions and volumetrically quantifies multicellular tumor spheroids

      hree-dimensional (3D) tumor spheroid models have gained increased recognition as important tools in cancer research and anti-cancer drug development. However, currently available imaging approaches employed in high-throughput screening drug discovery platforms e.g. bright field, phase contrast, and fluorescence microscopies, are unable to resolve 3D structures deep inside (>50 μm) tumor spheroids. In this study, we established a label-free, non-invasive optical coherence tomography (OCT) imaging platform to characterize 3D morphological and physiological information of multicellular tumor spheroids (MCTS) growing from ~250 μm up to ~600 μm in height over 21 days. In particular, tumor spheroids of two cell lines glioblastoma ...

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      Mentions: Lehigh University Chao Zhou
    18. See all articles

  3. Recent Articles From Around The Web

    1. Automatic vessel detection by means of brightness profile characterization in OCT images

      Explore ACM Digital Library Ophthalmology
      Automatic vessel detection by means of brightness profile characterization in OCT images

      Optical Coherence Tomography (OCT) is a well-established medical imaging technique that allows the analysis of the eye fundus characteristics in real time. These images enable the experts to make a clinical evaluation of the retinal vasculature, whose morphology provides relevant information for diseases like diabetes, hypertension or arteriosclerosis. In this paper, we present a novel proposal for the automatic vasculature identification in retinal OCT images. To achieve this, we analyse the intensity profiles between representative retinal layers, previously segmented. Then, two statistical models are generated using representative samples of vessel and non-vessel profiles. The analysis of both statistical models let ...

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    2. A COMPARATIVE STUDY OF CENTRAL FOVEAL THICKNESS PRE AND POST CATARACT SURGERY USING SD-OPTICAL COHERENCE TOMOGRAPHY

      Explore jebmh.com Ophthalmology
      A COMPARATIVE STUDY OF CENTRAL FOVEAL THICKNESS PRE AND POST CATARACT SURGERY USING SD-OPTICAL COHERENCE TOMOGRAPHY

      BACKGROUND The purpose of this study is to compare central foveal thickness (CFT) of patients preoperatively and postoperatively cataract surgery using SD- optical coherence tomography and to correlate CFT with vision. MATERIALS AND METHODS 200 eyes of 100 patients were examined and two groups were formed. Group-A was considered as the control group in the study and eyes in group-B were operated for cataract using SICS technique. The central foveal thickness (CFT) in each group was measured using SD-OCT machine (Cirrus Zeiss) preoperatively, postoperatively on day 1, week 1 and after 1 month and the data was compiled and compared ...

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    3. Optical coherence tomography findings and successful repair of retina detachment in Knobloch syndrome

      Explore djo.harvard.edu Ophthalmology

      A 7-year-old Afghani girl was referred to the retina clinic of Massachusetts Eye and Ear for a chronic-appearing, macula-off retinal detachment in the left eye. On examination, best-corrected visual acuity was 20/400 in the right eye and 20/800 in the left eye. She had bilateral horizontal nystagmus. Ophthalmoscopy revealed prominent choroidal vessels, chorioretinal atrophy in the macular area, attenuated retinal vasculature, and pale optic discs bilaterally. Spectral domain optical coherence tomography demonstrated atrophy of the choriocapillaris and the retinal pigment epithelium, retinal thinning, and abnormal foveal contour. In the right eye, findings were reminiscent of dome shape maculopathy ...

      Read Full Article
      Mentions: Harvard University Massachusetts Eye and Ear Infirmary

    4. Feature definition, analysis and selection for cystoid region characterization in Optical Coherence Tomography

      Explore ScienceDirect Ophthalmology
      Feature definition, analysis and selection for cystoid region characterization in Optical Coherence Tomography

      Optical Coherence Tomography (OCT) is, nowadays, a clinical standard imaging technique in opthalmology as it provides more information than other classical modalities as can be, for instance, retinographies. OCT scans show a 3D representation of the real layout of the eye fundus in a non-invasive way, letting clinicians inspect deeply the retinal layers in a cross-sectional visualization. For that reason, OCT scans are commonly used in the study of the retinal morphology and the identification of pathological structures. Among them, an appropriate identification and analysis of any present intraretinal cystoid region is crucial to perform an adequate diagnosis of the ...

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    5. Automatic spectral calibration for polarization-sensitive optical coherence tomography

      Explore OSA | OSA Publishing
      Automatic spectral calibration for polarization-sensitive optical coherence tomography

      Accurate wavelength assignment is important for Fourier domain polarizationsensitive optical coherence tomography. Incorrect wavelength mapping between the orthogonal horizontal (H) and vertical (V) polarization channels leads to broadening the axial point spread function and generating polarization artifacts. To solve the problem, we propose an automatic spectral calibration method by seeking the optimal calibration coefficient between wavenumber kH and kV. The method first performs a rough calibration to get the relationship between the wavelength λ and the pixel number x of the CCD for each channel. And then a precise calibration is taken to bring both polarization interferograms in the same k ...

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      Mentions: Xiangzhao Wang Chinese Academy of Sciences Zhongliang Li

    6. Using polarisation-sensitive optical coherence tomography and mechanical indentation to assess cartilage degeneration in the bovine model of early osteoarthritis

      Explore arxiv.org
      Using polarisation-sensitive optical coherence tomography and mechanical indentation to assess cartilage degeneration in the bovine model of early osteoarthritis

      Recent studies have shown potential for using polarisation sensitive optical coherence tomography (PS-OCT) to study cartilage morphology, and this presents a useful real-time non-invasive tool for detecting osteoarthritic changes. However, there has been relatively limited ability of this method to quantify the subtle changes in the early stages of joint degeneration. In this study, we investigate the ability of PS-OCT to detect microscale degenerative changes in cartilage, following compression, using a validated animal model of early cartilage degeneration, and a special indentation technique. It was found that PS-OCT was able to detect and quantify microstructural changes between healthy and early ...

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      Mentions: University of Auckland Frederique Vanholsbeeck

    7. Cystoid macular edema segmentation of Optical Coherence Tomography images using fully convolutional neural networks and fully connected CRFs

      Explore arxiv.org Ophthalmology
      Cystoid macular edema segmentation of Optical Coherence Tomography images using fully convolutional neural networks and fully connected CRFs

      In this paper we present a new method for cystoid macular edema (CME) segmentation in retinal Optical Coherence Tomography (OCT) images, using a fully convolutional neural network (FCN) and a fully connected conditional random fields (dense CRFs). As a first step, the framework trains the FCN model to extract features from retinal layers in OCT images, which exhibit CME, and then segments CME regions using the trained model. Thereafter, dense CRFs are used to refine the segmentation according to the edema appearance. We have trained and tested the framework with OCT images from 10 patients with diabetic macular edema (DME ...

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      Mentions: University of Kent

    8. Simultaneous, label-free, multispectral fluorescence lifetime imaging and optical coherence tomography using a double-clad fiber

      Explore OSA | OSA Publishing
      Simultaneous, label-free, multispectral fluorescence lifetime imaging and optical coherence tomography using a double-clad fiber

      We present a novel fiber-based imaging platform that allows simultaneous fluorescence lifetime imaging (FLIm) and optical coherence tomography (OCT) using a double-clad fiber. This platform acquires co-registered images showing structural and compositional contrast in unlabeled biological samples by scanning the fiber tip across the sample surface. In this Letter, we report a characterization of each modality and show examples of co-registered FLIm and OCT images acquired from a lemon segment and a section of human coronary artery. The close comparison between the combined FLIm and OCT images and a co-registered histology section provides a qualitative validation of the technique and ...

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    9. Effect of Post-Dilatation Following Primary PCI With Everolimus-Eluting Bioresorbable Scaffold Versus Everolimus-Eluting Metallic Stent Implantation: An Angiographic and Optical Coherence Tomography TROFI II Substudy

      Explore ScienceDirect Cardiology
      Effect of Post-Dilatation Following Primary PCI With Everolimus-Eluting Bioresorbable Scaffold Versus Everolimus-Eluting Metallic Stent Implantation: An Angiographic and Optical Coherence Tomography TROFI II Substudy

      Objectives This study sought to investigate the effect of post-dilatation on angiographic and intracoronary imaging parameters in the setting of primary percutaneous coronary intervention comparing the everolimus-eluting bioresorbable scaffold (BRS) with the everolimus-eluting metallic stent (EES). Background Routine post-dilatation of BRS has been suggested to improve post-procedural angiographic and subsequent device-related clinical outcomes. Methods In the ABSORB STEMI TROFI II trial, 191 patients with ST-segment elevation myocardial infarction were randomly assigned to treatment with BRS (n = 95) or EES (n = 96). Minimal lumen area and healing score as assessed by optical coherence tomography at 6 months were compared between BRS- ...

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      Mentions: Academic Medical Center at the University of Amsterdam Patrick W. Serruys Stephan Windecker

    11. Quantitative optical coherence tomography angiography of macular vascular structure and foveal avascular zone in glaucoma

      Explore Journals | PLOS Ophthalmology
      Quantitative optical coherence tomography angiography of macular vascular structure and foveal avascular zone in glaucoma

      Objective The study aimed to evaluate the quantitative characteristics of the macular vessel density (VD) and foveal avascular zone (FAZ) in glaucoma using optical coherence tomography angiography (OCT-A). Design Cross-sectional, age- and sex-matched case–control study. Methods Fifty-two eyes of 52 patients with primary open angle glaucoma and 52 eyes from 52 healthy participants were recruited retrospectively. OCT-A was performed on a 3 x 3-mm macular region centered on the fovea. OCT-A scans were manually graded to define the FAZ. Parafoveal VD in superficial and deep retina were analyzed in the circular- and quadrant-segmented zone. The FAZ parameters included size ...

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      Mentions: Asan Medical Center University of Ulsan Michael S. Kook

    12. Choroidal Variations in Diabetic Macular Edema: Fluorescein Angiography and Optical Coherence Tomography

      Explore Taylor & Francis Online Ophthalmology
      Choroidal Variations in Diabetic Macular Edema: Fluorescein Angiography and Optical Coherence Tomography

      Purposes : To (i) evaluate variations in choroidal thickness (CT) and choroidal volume (CV) in diabetic macular edema (DME), as demonstrated by fluorescein angiography (FA) and enhanced depth-imaging (EDI) optical coherence tomography (OCT) (EDI-OCT) and (ii) correlate these variations with visual acuity. Methods : This study was a retrospective observational case series of patients with diabetic retinopathy (DR) and DME. The study groups comprised 77 DR patients ( n = 87), all of whom underwent color fundus photography, FA, and OCT on the same day. The control group comprised 25 age-matched healthy individuals ( n = 50 eyes). CT was measured by manual segmentation (EDI-OCT built-in ...

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      Mentions: Shanghai Jiao Tong University

    13. Flexible wide-field optical micro-angiography based on Fourier-domain multiplexed dual-beam swept source optical coherence tomography

      Explore Wiley Online Library
      Flexible wide-field optical micro-angiography based on Fourier-domain multiplexed dual-beam swept source optical coherence tomography

      Wide-field optical coherence tomography angiography (OCTA) is gaining interest in clinical imaging applications. In this pursuit, it is challenging to maintain the imaging resolution and sensitivity throughout the wide field of view (FoV). Here, we propose a novel method/system of dual-beam arrangement and Fourier domain multiplexing to achieve wide field OCTA when imaging the uneven surface samples. The proposed system provides two separate FoVs, with flexibility that the imaging area, focus of the imaging beam and imaging depth range can be individually adjusted for each FoV, leading to either 1) increased system imaging FoV or 2) capability of targeting ...

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      Mentions: University of Washington Ruikang K. Wang

    14. Baton Handover At Blackbird Robotics

      Explore biospace.com NDE/NDT
      Baton Handover At Blackbird Robotics

      Since 2008, Blackbird Robotersysteme has stood for intelligent system solutions in the robot-assisted laser welding field. Its internally developed control technology and user software are combined with scan systems of affiliated company SCANLAB to create top-performing welding systems. The product range consistently focuses on requirements of customers in the automotive branch and other industrial sectors, while offering increasingly highly integrated system solutions. A laser welding system with OCT (optical coherence tomography) technology for integrated seam tracking and process monitoring, newly introduced just this June, is proof of the company's strategic advancement to system supplier. And international growth, particularly in ...

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      Mentions: Blackbird Robotersysteme GmbH SCANLAB GmbH

    15. Multi-Modal Imaging Including Optical Coherence Tomography Angiography in Patients With Posterior Multifocal Placoid Pigment Epitheliopathy

      Explore Healio.com Ophthalmology
      Multi-Modal Imaging Including Optical Coherence Tomography Angiography in Patients With Posterior Multifocal Placoid Pigment Epitheliopathy

      ACKGROUND AND OBJECTIVE: New imaging methods provide novel insights into the pathogenesis of acute posterior multifocal placoid pigment epitheliopathy (APMPPE). PATIENTS AND METHODS: Four patients (eight eyes) in acute, subacute, and late phases of the disease were analyzed with multi-modal imaging methods including optical coherence tomography angiography (OCTA), structural OCT, fundus photography, and fundus autofluorescence. One patient was observed during the entire disease course. RESULTS: In acute and subacute phases of the disease, an early blockage in fluorescein angiography was found. OCTA showed perfusion defects in choriocapillaris and choroid slabs. During the course of disease, perfusion deficits observed in OCTA ...

      Read Full Article
      16. See all articles
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    1. (4 articles) University of Southern California
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    1. (2 articles) Scott E. Fraser
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    1. (2 articles) NKT Photonics
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  9. Picture Gallery

    The Validity of the Diagnosis of Plant Leaf Infections Using Non-Destructive Optical Inspection Technique and Depth-Scan Signal Analysis Optical coherence tomography angiography retinal vascular network assessment in multiple sclerosis CNNs Enable Accurate and Fast Segmentation of Drusen in Optical Coherence Tomography Tissue characterization with depth-resolved attenuation coefficient and backscatter term in intravascular optical coherence tomography images Performance characteristics of optical coherence tomography in assessment of Barrett's esophagus and esophageal cancer: systematic review Serial 5-Year Evaluation of Side Branches Jailed by Bioresorbable Vascular Scaffolds Using 3-Dimensional Optical Coherence Tomography Dual-beam manually-actuated distortion-corrected imaging (DMDI) with micromotor catheters Rapid measurement of transversal flow velocity vector with high spatial resolution using speckle decorrelation optical coherence tomography Evaluating biomechanical properties of murine embryos using Brillouin microscopy and optical coherence tomography Register Now for the International Congress on OCT Angiography, "en face" OCT, and Advances in OCT on December 15th in Rome Italy which Already has over 1,000 Attendees Automatic Identification of Weave Patterns of Checked and Colored Fabrics Using Optical Coherence Tomography Depolarization signatures map gold nanorods within biological tissue

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    1. Optovue continues to lead innovation in Optical Coherence Tomography (OCT) imaging with the first non-contact technique of measuring the epithelial layer of the cornea...Our epi-mapping software has been the subject of more than 200 publications, underscoring its importance and value in the care of patients with corneal and ocular surface conditions. With epi-mapping, physicians are able to quantify epithelial thickness in patients in a manner that is suitable for daily clinical practice.
      By Jay Wei
    2. Combining en-face OCT with movement detection within blood vessels, we get OCT-A, and with it a new imaging era.
      By Eric H. Souied
    3. Obtaining the Category III CPT code for OCT of the skin is an important step towards our goal of obtaining reimbursement and coverage, and we welcome the new codes that can be used by clinicians to record their clinical use of VivoSight OCT in their practice.
      By Jon Holmes
    4. We showed that you can take effectively any OCT system out there and, with minimal changes, boost its resolution to the point where it can detect anatomical features smaller than the size of a typical cell.
      By Adam de la Zerda
    5. This honor highlights the commitment Avinger has to bring the most advanced technology to market for physicians dedicated to treating PAD and their patients who are affected by this disease...Pantheris radically changes the treatment of vascular disease and the Edison Award represents a win for our entire Lumivascular portfolio.
      By John B. Simpson
    6. While we have been actively advancing our lesion assessment technology for the last two years, we are very pleased to see that the significant Series B investment will give MedLumics the means to complete our best-in-class product, conduct a series of international clinical trials to prove its safety and efficacy, and market it to specialist centers. As the company advances and grows into new areas, we will now expand and develop the team internationally.
      By Eduardo Margallo Balbás
    7. It's the most rapidly adopted ophthalmic technology in history.
      By Joel S. Schuman
    8. Our OCT Angiography congresses is a major force in promoting the transition from FA to OCTA by educating the ophthalmologists .
      By Bruno Lumbroso
    9. The development of OCT in the early 1990s greatly benefited from components and methods used in fiber-optical communications...And still, 25 years later, advances in the optical communications industry continue to greatly benefit OCT.
      By James G. Fujimoto
    10. Research by our group at MIT and our collaborators at Praevium Research and Thorlabs indicated that the coherence length of the VCSEL source was orders of magnitude longer than other swept laser technologies suitable for OCT, which suggested the possibility of long-range OCT imaging.
      By Benjamin M. Potsaid