1. Feature Of The Week

    The study of mosquitoes and analysis of their behavior are of crucial importance in the on-going efforts to control the alarming increase in mosquito-borne diseases. Furthermore, a non-destructive and real-time imaging technique to study the anatomical features of mosquito specimens can greatly aid the study of mosquitoes. In this study, we demonstrate the three-dimensional imaging capabilities of optical coherence tomography (OCT) for structural analysis of Anopheles sinensis mosquitoes. The anatomical features of An. sinensis head, thorax, and abdominal regions, along with the morphology of internal structures, such as foregut, midgut, and hindgut, were studied using OCT imaging. Two-dimensional and three-dimensional OCT images, used in conjunction with histological images, proved useful for anatomical analysis of mosquito specimens. By presenting this work as an initial study, we demonstrate the applicability of OCT for future mosquito-related entomological research, and also in identifying changes in mosquito anatomical structure.

    For more information see recent Article. Courtesy Naresh Kumar Ravichandran from Kyungpook National University. To share this article click Here.

  2. Featured Articles

    1. Optical coherence tomography angiography retinal vascular network assessment in multiple sclerosis

      Explore SAGE Journals Neurology , Ophthalmology
      Optical coherence tomography angiography retinal vascular network assessment in multiple sclerosis

      Background: Optical coherence tomography (OCT) angiography is a new method to assess the density of the vascular networks. Vascular abnormalities are considered involved in multiple sclerosis (MS) pathology. Objective: To assess the presence of vascular abnormalities in MS and to evaluate their correlation to disease features. Methods: A total of 50 MS patients with and without history of optic neuritis (ON) and 46 healthy subjects were included. All underwent spectral domain (SD)-OCT and OCT angiography. Clinical history, Expanded Disability Status Scale (EDSS), Multiple Sclerosis Severity Score (MSSS) and disease duration were collected. Results: Angio-OCT showed a vessel density reduction ...

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    2. CNNs Enable Accurate and Fast Segmentation of Drusen in Optical Coherence Tomography

      Explore Home - Springer Ophthalmology
      CNNs Enable Accurate and Fast Segmentation of Drusen in Optical Coherence Tomography

      Optical coherence tomography (OCT) is used to diagnose and track progression of age-related macular degeneration (AMD). Drusen, which appear as bumps between Bruch’s membrane (BM) and the retinal pigment epithelium (RPE) layer, are among the most important biomarkers for staging AMD. In this work, we develop and compare three automated methods for Drusen segmentation based on the U-Net convolutional neural network architecture. By cross-validating on more than 50, 000 annotated images, we demonstrate that all three approaches achieve much better accuracy than a current state-of-the-art method. Highest accuracy is achieved when the CNN is trained to segment the BM ...

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      Mentions: University of Bonn Frank G. Holz

    3. Tissue characterization with depth-resolved attenuation coefficient and backscatter term in intravascular optical coherence tomography images

      Explore SPIE Digital Library Cardiology
      Tissue characterization with depth-resolved attenuation coefficient and backscatter term in intravascular optical coherence tomography images

      An important application of intravascular optical coherence tomography (IVOCT) for atherosclerotic tissue analysis is using it to estimate attenuation and backscatter coefficients. This work aims at exploring the potential of the attenuation coefficient, a proposed backscatter term, and image intensities in distinguishing different atherosclerotic tissue types with a robust implementation of depth-resolved (DR) approach. Therefore, the DR model is introduced to estimate the attenuation coefficient and further extended to estimate the backscatter-related term in IVOCT images, such that values can be estimated per pixel without predefining any delineation for the estimation. In order to exclude noisy regions with a weak ...

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      Mentions: Leiden University Academic Medical Center at the University of Amsterdam Patrick W. Serruys

    4. Performance characteristics of optical coherence tomography in assessment of Barrett's esophagus and esophageal cancer: systematic review

      Explore Journals Gastroenterology
      Performance characteristics of optical coherence tomography in assessment of Barrett's esophagus and esophageal cancer: systematic review

      Optical coherence tomography (OCT) can generate high-resolution images of the esophagus that allows cross-sectional visualization of esophageal wall layers. We conducted a systematic review to assess the utility of OCT for diagnosing of esophageal intestinal metaplasia (IM; Barrett's esophagus BE)), dysplasia, cancer and staging of early esophageal cancer. English language human observational studies and clinical trials published in PubMed and Embase were included if they assessed any of the following: (i) in-vivo features and accuracy of OCT at diagnosing esophageal IM, sub-squamous intestinal metaplasia (SSIM), dysplasia, or cancer, and (ii) accuracy of OCT in staging esophageal cancer. Twenty-one of ...

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    5. Serial 5-Year Evaluation of Side Branches Jailed by Bioresorbable Vascular Scaffolds Using 3-Dimensional Optical Coherence Tomography

      Explore Circulation Cardiology
      Serial 5-Year Evaluation of Side Branches Jailed by Bioresorbable Vascular Scaffolds Using 3-Dimensional Optical Coherence Tomography

      Background— The long-term fate of Absorb bioresorbable vascular scaffold (Abbott Vascular, Santa Clara, CA) struts jailing side branch ostia has not been clarified. We therefore evaluate serially (post-procedure and at 6 months, 1, 2, 3, and 5 years) the appearance and fate of jailed Absorb bioresorbable vascular scaffold struts. Methods and Results— We performed 3-dimensional optical coherence tomographic analysis of the ABSORB Cohort B trial (A Clinical Evaluation of the Bioabsorbable Everolimus Eluting Coronary Stent System in the Treatment of Patients With De Novo Native Coronary Artery Lesions) up to 5 years using a novel, validated cut-plane analysis method. We ...

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      Mentions: Patrick W. Serruys Stephan Windecker Yoshinobu Onuma

    6. Dual-beam manually-actuated distortion-corrected imaging (DMDI) with micromotor catheters

      Explore OSA | OSA Publishing
      Dual-beam manually-actuated distortion-corrected imaging (DMDI) with micromotor catheters

      e present a new paradigm for performing two-dimensional scanning called dual-beam manually-actuated distortion-corrected imaging (DMDI). DMDI operates by imaging the same object with two spatially-separated beams that are being mechanically scanned rapidly in one dimension with slower manual actuation along a second dimension. Registration of common features between the two imaging channels allows remapping of the images to correct for distortions due to manual actuation. We demonstrate DMDI using a 4.7 mm OD rotationally scanning dual-beam micromotor catheter (DBMC). The DBMC requires a simple, one-time calibration of the beam paths by imaging a patterned phantom. DMDI allows for distortion ...

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      Mentions: British Columbia Cancer Agency

    7. Rapid measurement of transversal flow velocity vector with high spatial resolution using speckle decorrelation optical coherence tomography

      Explore OSA | OSA Publishing
      Rapid measurement of transversal flow velocity vector with high spatial resolution using speckle decorrelation optical coherence tomography

      We propose and demonstrate a novel method that uses only three sets of B-scans to accurately determine both the direction and the speed of a transversal flow using speckle decorrelation optical coherence tomography. Our tri-scan method has the advantages of high measurement speed, high spatial resolution, and insensitivity to the flow speed. By introducing error maps, we show that the flow angle inaccuracy can be minimized by choosing the measurement result with a lesser error between results obtained from the

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      Mentions: Yimin Wang General Photonics Steve Yao

    8. Evaluating biomechanical properties of murine embryos using Brillouin microscopy and optical coherence tomography

      Explore SPIE Digital Library Developmental Biology
      Evaluating biomechanical properties of murine embryos using Brillouin microscopy and optical coherence tomography

      Embryogenesis is regulated by numerous changes in mechanical properties of the cellular microenvironment. Thus, studying embryonic mechanophysiology can provide a more thorough perspective of embryonic development, potentially improving early detection of congenital abnormalities as well as evaluating and developing therapeutic interventions. A number of methods and techniques have been used to study cellular biomechanical properties during embryogenesis. While some of these techniques are invasive or involve the use of external agents, others are compromised in terms of spatial and temporal resolutions. We propose the use of Brillouin microscopy in combination with optical coherence tomography (OCT) to measure stiffness as well ...

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      Mentions: University of Maryland Kirill V. Larin University of Houston

    9. Register Now for the International Congress on OCT Angiography, "en face" OCT, and Advances in OCT on December 15th in Rome Italy which Already has over 1,000 Attendees

      Explore Optical Coherence Tomography News
      Register Now for the International Congress on OCT Angiography, "en face" OCT, and Advances in OCT on December 15th in Rome Italy which Already has over 1,000 Attendees

      The fifth international congress on OCT Angiography, "en face" OCT, and advances in OCT will take place in Rome Italy on December 15th an 16th. The meeting has its own personality: it brings together both the clinical and basic science communities, has high scientific contents and good organization, friendly atmosphere, sweet weather and Rome beauty. The conference organizers include Bruno Lumbroso, David Huang, Gabriel Coscas, Yali Jia, K. Bailey Freund, Richard Rosen, Philip Rosenfeld, David Sarraf, Eric Souied, Richard Spaide, Giovanni Staurenghi, Nadia Waheed. Quan Dong Nguyen, SriniVas Sadda, Yves Cohen, Wolfgang Drexler, Joseph Carroll, and Ursula Schmidt Erfurth. The ...

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      Mentions: Philip J. Rosenfeld David Huang Wolfgang Drexler

    10. Automatic Identification of Weave Patterns of Checked and Colored Fabrics Using Optical Coherence Tomography

      Explore IEEE Xplore NDE/NDT
      Automatic Identification of Weave Patterns of Checked and Colored Fabrics Using Optical Coherence Tomography

      Identifying the weave pattern of fabrics can be done manually or automatically. Carrying out the weave recognition automatically will reduce the procedure time and error rates since automatic systems can perform successive measurements at high speeds and with great repeatability and quality. Woven fabric repeat identification systems that are automatic, usually work by employing complex algorithms and techniques. It is known that these automatic techniques struggle when trying to identify highly complex patterns, composing of a combination of different structures, figures, and colors. For example, image processing algorithms are known to make errors when dealing with checked and colored fabrics ...

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    11. Depolarization signatures map gold nanorods within biological tissue

      Explore lmrt.mit.edu
      Depolarization signatures map gold nanorods within biological tissue

      Owing to their electromagnetic properties, tunability and biocompatibility, gold nanorods are being investigated as multifunctional probes for a range of biomedical applications. However, detection beyond the reach of traditional fluorescence and two-photon approaches and quantitation of their concentration in biological tissue remain challenging tasks in microscopy. Here, we show how the size and aspect ratio that impart gold nanorods with their plasmonic properties also make them a source of entropy. We report on how depolarization can be exploited as a strategy to visualize gold nanorod diffusion and distribution in biologically relevant scenarios ex vivo, in vitro and in vivo. We ...

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      Mentions: Brett E. Bouma Massachusetts General Hospital Harvard University

    12. Thermo-elastic optical coherence tomography

      Explore OSA | OSA Publishing
      Thermo-elastic optical coherence tomography

      The absorption of nanosecond laser pulses induces rapid thermo-elastic deformation in tissue. A sub-micrometer scale displacement occurs within a few microseconds after the pulse arrival. In this Letter, we investigate the laser-induced thermo-elastic deformation using a 1.5 MHz phase-sensitive optical coherence tomography (OCT) system. A displacement image can be reconstructed, which enables a new modality of phase-sensitive OCT, called thermo-elastic OCT. An analysis of the results shows that the optical absorption is a dominating factor for the displacement. Thermo-elastic OCT is capable of visualizing inclusions that do not appear on the structural OCT image, providing additional tissue type information.

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      Mentions: Robert A. Huber Delft University of Technology Chinese Academy of Sciences

    13. Visualization and Detection of Ciliary Beating Pattern and Frequency in the Upper Airway using Phase Resolved Doppler Optical Coherence Tomography

      Explore Nature Publishing Group Pulmonology
      Visualization and Detection of Ciliary Beating Pattern and Frequency in the Upper Airway using Phase Resolved Doppler Optical Coherence Tomography

      Ciliary motion plays a critical role in the overall respiratory health of the upper airway. These cilia beat at a native frequency and in a synchronized pattern to continuously transport foreign particulate trapped in a layer of mucous out of the upper airway. Disruption of ciliary motion can lead to severe respiratory diseases and compromised respiratory function. Currently, the study of cilia requires expensive high speed cameras and high powered microscopes which is unsuitable for in vivo imaging and diagnosis. Doppler based optical coherence tomography has the potential to visualize the microscopic motion of cilia during their beating cycle. We ...

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      Mentions: Zhongping Chen UC Irvine Brian J. F. Wong

    14. Human Factor and Usability Testing of a Binocular Optical Coherence Tomography System

      Explore TVST Journal Ophthalmology
      Human Factor and Usability Testing of a Binocular Optical Coherence Tomography System

      Purpose : To perform usability testing of a binocular optical coherence tomography (OCT) prototype to predict its function in a clinical setting, and to identify any potential user errors, especially in an elderly and visually impaired population. Methods : Forty-five participants with chronic eye disease (mean age 62.7 years) and 15 healthy controls (mean age 53 years) underwent automated eye examination using the prototype. Examination included ‘whole-eye' OCT, ocular motility, visual acuity measurement, perimetry, and pupillometry. Interviews were conducted to assess the subjective appeal and ease of use for this cohort of first-time users. Results : All participants completed the full suite ...

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      Mentions: University College London University of Ulster Pearse A. Keane

    15. From lab to clinic

      Explore Physics Today
      From lab to clinic

      Last month I visited my eye doctor, Harold Jacobson, for a routine checkup. After reading rows of ever-smaller letters, just as I had when my eyes were first tested in the 1970s, I asked him what new technology he was most excited about. “Optical coherence tomography,” he replied. “It’s a game changer!” Jacobson had bought an OCT scanner after my previous visit, so I got to see the game changer firsthand. As a patient, I briefly looked into a pair of eyepieces. As an ophthalmologist, Jacobson reviewed a wealth of information on the scanner’s screen. Beside cross sections ...

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      Mentions: Carmen A. Puliafito James G. Fujimoto Carl Zeiss Meditec

    16. Optical coherence tomography detects necrotic regions and volumetrically quantifies multicellular tumor spheroids

      Explore Cancer Research Oncology
      Optical coherence tomography detects necrotic regions and volumetrically quantifies multicellular tumor spheroids

      hree-dimensional (3D) tumor spheroid models have gained increased recognition as important tools in cancer research and anti-cancer drug development. However, currently available imaging approaches employed in high-throughput screening drug discovery platforms e.g. bright field, phase contrast, and fluorescence microscopies, are unable to resolve 3D structures deep inside (>50 μm) tumor spheroids. In this study, we established a label-free, non-invasive optical coherence tomography (OCT) imaging platform to characterize 3D morphological and physiological information of multicellular tumor spheroids (MCTS) growing from ~250 μm up to ~600 μm in height over 21 days. In particular, tumor spheroids of two cell lines glioblastoma ...

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      Mentions: Lehigh University Chao Zhou
    17. See all articles

  3. Recent Articles From Around The Web

    1. Multi-Modal Imaging Including Optical Coherence Tomography Angiography in Patients With Posterior Multifocal Placoid Pigment Epitheliopathy

      Explore Healio.com Ophthalmology
      Multi-Modal Imaging Including Optical Coherence Tomography Angiography in Patients With Posterior Multifocal Placoid Pigment Epitheliopathy

      ACKGROUND AND OBJECTIVE: New imaging methods provide novel insights into the pathogenesis of acute posterior multifocal placoid pigment epitheliopathy (APMPPE). PATIENTS AND METHODS: Four patients (eight eyes) in acute, subacute, and late phases of the disease were analyzed with multi-modal imaging methods including optical coherence tomography angiography (OCTA), structural OCT, fundus photography, and fundus autofluorescence. One patient was observed during the entire disease course. RESULTS: In acute and subacute phases of the disease, an early blockage in fluorescein angiography was found. OCTA showed perfusion defects in choriocapillaris and choroid slabs. During the course of disease, perfusion deficits observed in OCTA ...

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    2. Simultaneous OCT and B-FAF in Eyes With Alteration of the Foveal Contour

      Explore Home - ClinicalTrials.gov Ophthalmology , Clinical Trials
      Simultaneous OCT and B-FAF in Eyes With Alteration of the Foveal Contour

      Some alterations of the foveal contour do not meet the criteria established for the definition of lamellar macular hole on the basis of optical coherence tomography (OCT). However, these alterations may show an appearance, on blue fundus autofluorescence (B-FAF) imaging, reminiscent of lamellar macular hole. The aim of the study is to evaluate in detail these alterations recording simultaneously OCT and B-FAF.

      Read Full Article
      Mentions: University of Milan

    3. Real-time optical coherence tomography coregistration with angiography in percutaneous coronary intervention–impact on physician decision-making: The OPTICO-integration study

      Explore Wiley Online Library Cardiology
      Real-time optical coherence tomography coregistration with angiography in percutaneous coronary intervention–impact on physician decision-making: The OPTICO-integration study

      Aims Intracoronary optical coherence tomography (OCT) imaging allows for high-resolution characterization of coronary lesions. Difficulties in matching cross-sectional OCT-images with angiographic lesion localization may limit optimal clinical utilization. We sought to prospectively assess the impact of a novel system of real-time OCT coregistration with angiography (ACR) on physician decision-making during percutaneous coronary interventions (PCI). Methods and Results Strategy for PCI (stent - length, - diameter, - strategy, landing zone) and PCI-optimization (stent-malappostion, -underexpansion, edge-dissections, geographical mismatch) was prospectively assessed in 50 patients with 58 coronary lesions after (I) angiography, (II) OCT imaging, and (III) ACR. Preprocedural OCT imaging altered stent-length (58.9%), diameter ...

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    4. Evaluation of retinal nerve fibre layer, ganglion cell layer and choroidal thickness with optical coherence tomography in migraine patients: a case-control study

      Explore Wiley Online Library Ophthalmology
      Evaluation of retinal nerve fibre layer, ganglion cell layer and choroidal thickness with optical coherence tomography in migraine patients: a case-control study

      Background Evaluation of retinal nerve fibre layer (RNFL), ganglion cell layer (GCL) and choroidal thickness (CT) with optical coherence tomography (OCT) in chronic migraine patients, to compare with healthy controls. Material and Method Ninety-four eyes of 47 chronic migraine patients (Group 1) and 68 eyes of 34 healthy individuals (Group 2) were included in this prospective case-control study. The right and left eyes were separately evaluated. Mean peripapillary RNFL thicknesses, mean GCL measured from superior and inferior quadrants, and mean CT were measured at three different regions (central, 500 μm nasal and temporal region of the fovea). Results There was ...

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    5. 2nd Canterbury Conference on Optical Coherence Tomography

      Explore ubaphodesa.com
      2nd Canterbury Conference on Optical Coherence Tomography

      The Applied Optics Group of the University of Kent organised the 2 nd Canterbury Conference on Optical Coherence Tomography (2CCOCT) with emphasis on broadband optical sources from the 6 th to the 8 th of September . 2CCOCT was an international conference with a total of 49 oral presentations and 10 poster presentations . Speakers came from all over the globe, covering countries like Argentina, Australia, Austria, Canada, China, Czech Republic, Denmark, France, Germany, Japan, New Zealand, Romania, Russia, the United Kingdom, the United States of America and Switzerland. The 49 oral presentations are divided into 13 student presentations, 15 invited speakers ...

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      Mentions: Université Pierre et Marie Curie Thorlabs George M. Dobre

    6. Optical Coherence Tomography Angiography to Better understand Glaucoma

      Explore Jaypee Journals Ophthalmology
      Optical Coherence Tomography Angiography to Better understand Glaucoma

      The term optical coherence tomography angiography (OCTA) comprises different OCT-based technologies which all allow noninvasive assessment of retinal perfusion, based on moving red blood cells. The main areas where OCTA is currently used are investigation of perfusion and vascular structure of the macular retina (e.g., in macular degenerations and diabetic macular diseases) and the disk and peripapillary retina (in glaucoma and other optic disk diseases). The current editorial provides a brief overview on the potential of OCTA and its use to measure perfusion in the peripapillary retina in glaucoma.

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      Mentions: Semmelweis University

    7. Clinical relevance of retinal structure in children with laser-treated retinopathy of prematurity versus controls – using optical coherence tomography

      Explore Wiley Online Library Ophthalmology
      Clinical relevance of retinal structure in children with laser-treated retinopathy of prematurity versus controls – using optical coherence tomography

      Purpose We aimed to assess the macular anatomy using spectral domain optical coherence tomography (SD-OCT), in children born preterm who had laser-treated retinopathy of prematurity (ROP), and to investigate the relationship between structural changes in macula and visual function. Methods Thirty-seven 3–8 years old children were included in the study in two groups: 20 children born preterm [(<34 weeks of gestation, birthweight (BW) <2000 g)] who had laser-treated ROP in the Neonatology Department, Municipal Clinical Emergency Hospital of Timisoara, Romania; and 17 controls (children born at term, without eye disease, matched for age and gender). Spectral domain optical coherence ...

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      Mentions: Victor Babes University of Medicine and Pharmacy

    8. University of Southern California Receives NIH Grant for Influence of Hair Bundle Properties on Cochlear Mechanics

      Explore Optical Coherence Tomography News Otolaryngology , Funding
      University of Southern California Receives NIH Grant for Influence of Hair Bundle Properties on Cochlear Mechanics

      University of Southern California Receives a 2017 NIH Grant for $37,696 Influence of Hair Bundle Properties on Cochlear Mechanics. The principal investigator is James Dewey. The program began in 2017 and ends in 2020. Below is a summary of the proposed work. Normal hearing depends on the delicate mechanotransduction apparatus of inner ear hair cells – the stereociliary hair bundle. Cochlear vibrations deflect the hair bundle, which converts mechanical stimulation to electrical signals via gating of mechanosensitive ion channels. Hair bundle transduction is critical for hearing, as it is required for afferent signaling by inner hair cells, and for activation ...

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      Mentions: National Institutes of Health University of Southern California

    9. Stanford University Receives NIH Grant for Imaging Structure and Function

      Explore Optical Coherence Tomography News Ophthalmology , Funding
      Stanford University Receives NIH Grant for Imaging Structure and Function

      Stanford University Receives a 2017 NIH Grant for $139,730 for Imaging Structure and Function. The principal investigator is Thomas Clandinin. The program began in 2017 and ends in 2018. Below is a summary of the proposed work. Imaging technologies such as confocal microscopy, multiphoton microscopy and super- resolution imaging as well as optical coherence tomography have transformed the ability of scientists to observe structural and functional changes in the visual system, in vivo and ex vivo, in both health and disease. The overarching goal of the imaging core is to transform the ability of vision scientists to use these ...

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      Mentions: National Institutes of Health Stanford University

    10. Optical Coherence Tomography Evolution in a Case of X-Linked Juvenile Retinoschisis: 15 Years of Follow-Up

      Explore Karger Publishers Ophthalmology
      Optical Coherence Tomography Evolution in a Case of X-Linked Juvenile Retinoschisis: 15 Years of Follow-Up

      Purpose: We present the evolution of X-linked juvenile retinoschisis (XLRS) in a male patient using optical coherence tomography (OCT) with a long-term follow-up time of 15 years. Case Description: A 10-year-old male patient presented at the Medical Retina Department of our hospital complaining for blurred vision in both eyes. At the initial presentation in 2001, his best corrected visual acuity (BCVA) was 6/12 in both eyes on the Snellen chart. Based on clinical and OCT findings, the diagnosis of XLRS was made, and it was confirmed by genetic testing. No treatment was performed, but the patient was regularly examined ...

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      Mentions: University of Athens

    11. Repeatability and Reproducibility of Superficial Macular Retinal Vessel Density Measurements Using Optical Coherence Tomography Angiography En Face Images

      Explore The JAMA Network Ophthalmology
      Repeatability and Reproducibility of Superficial Macular Retinal Vessel Density Measurements Using Optical Coherence Tomography Angiography En Face Images

      Importance The repeatability and reproducibility of quantitative metrics from optical coherence tomographic angiography (OCTA) must be assessed before these data can be confidently interpreted in clinical research and practice. Objective To evaluate the repeatability and reproducibility of OCTA-derived retinal vascular quantitative metrics. Design, Setting and Participants In this cross-sectional study, 21 healthy volunteers (42 eyes) and 22 patients with retinal disease (22 eyes), including 14 with age-related macular degeneration, 3 with epiretinal membrane, 2 with diabetic retinopathy, 2 with myopic macular degeneration, and 1 with retinal vein occlusion, were enrolled. Participants were recruited from September 1 through November 31, 2016 ...

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      Mentions: University of Southern California Carl Zeiss Meditec Srinivas R. Sadda

    12. Macular retinal and choroidal thickness in unilateral amblyopia using swept-source optical coherence tomography

      Explore BMC Ophthalmology Ophthalmology
      Macular retinal and choroidal thickness in unilateral amblyopia using swept-source optical coherence tomography

      Background To investigate macular retinal and choroidal thickness in amblyopic eyes compared to that in fellow and normal eyes using swept-source optical coherence tomography (SS-OCT). Methods This study examined 31 patients with hyperopic anisometropic amblyopia (6.9 ± 3.8 years, mean ± standard deviation), 15 patients with strabismic amblyopia without anisometropia (7.9 ± 4.2 years), and 24 age-matched controls (7.8 ± 3.3 years). Retinal and choroidal thickness was measured by 3D scans using SS-OCT. A 6-mm area around the fovea was automatically analyzed using the Early Treatment Diabetic Retinopathy Study map. The thickness from SS-OCT was corrected for magnification ...

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    13. Optical coherence tomography angiography in glaucoma: a mini-review

      Explore F1000Research Ophthalmology
      Optical coherence tomography angiography in glaucoma: a mini-review

      The advent of optical coherence tomography angiography (OCT-A) provides a new opportunity to visualize the retinal vasculature in a non-invasive and dye-free manner which may help identify vascular abnormalities in glaucoma. While a reduction in retinal and optic nerve head vessel densities and blood flow indexes measured by OCT-A has been demonstrated in patients with glaucoma in many studies, it is unclear whether OCT-A provides additional information for the detection and monitoring of glaucoma compared with OCT measurements such as retinal nerve fiber layer thickness, neuroretinal rim width, and ganglion cell inner plexiform layer thickness. Longitudinal studies are needed to ...

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      Mentions: Chris K. S. Leung The Chinese University of Hong Kong

    15. Cilioretinal Artery Imaged with Optical Coherence Tomography Angiography

      Explore Ophthalmology Ophthalmology
      Cilioretinal Artery Imaged with Optical Coherence Tomography Angiography

      A 48-year-old woman presented with peripapillary chorioretinal atrophy and cilioretinal artery in the left eye without other findings (Fig 1A). Optical coherence tomography angiography (OCTA) through full-thickness retinal segmentation (Fig 1B) showed intact retinal perfusion. The cilioretinal artery arose from the temporal margin of the optic nerve and coursed into the retina, resembling a hook.

      Read Full Article
      16. See all articles
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  9. Picture Gallery

    Optical coherence tomography angiography retinal vascular network assessment in multiple sclerosis CNNs Enable Accurate and Fast Segmentation of Drusen in Optical Coherence Tomography Tissue characterization with depth-resolved attenuation coefficient and backscatter term in intravascular optical coherence tomography images Performance characteristics of optical coherence tomography in assessment of Barrett's esophagus and esophageal cancer: systematic review Serial 5-Year Evaluation of Side Branches Jailed by Bioresorbable Vascular Scaffolds Using 3-Dimensional Optical Coherence Tomography Dual-beam manually-actuated distortion-corrected imaging (DMDI) with micromotor catheters Rapid measurement of transversal flow velocity vector with high spatial resolution using speckle decorrelation optical coherence tomography Evaluating biomechanical properties of murine embryos using Brillouin microscopy and optical coherence tomography Register Now for the International Congress on OCT Angiography, "en face" OCT, and Advances in OCT on December 15th in Rome Italy which Already has over 1,000 Attendees Automatic Identification of Weave Patterns of Checked and Colored Fabrics Using Optical Coherence Tomography Depolarization signatures map gold nanorods within biological tissue Thermo-elastic optical coherence tomography

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    7. It's the most rapidly adopted ophthalmic technology in history.
      By Joel S. Schuman
    8. Our OCT Angiography congresses is a major force in promoting the transition from FA to OCTA by educating the ophthalmologists .
      By Bruno Lumbroso
    9. The development of OCT in the early 1990s greatly benefited from components and methods used in fiber-optical communications...And still, 25 years later, advances in the optical communications industry continue to greatly benefit OCT.
      By James G. Fujimoto
    10. Research by our group at MIT and our collaborators at Praevium Research and Thorlabs indicated that the coherence length of the VCSEL source was orders of magnitude longer than other swept laser technologies suitable for OCT, which suggested the possibility of long-range OCT imaging.
      By Benjamin M. Potsaid