1. Featured Articles

    1. Use of optical coherence tomography deemed feasible after first-in-human analysis

      Explore NeuroNews International Cardiology , Neurology
      Use of optical coherence tomography deemed feasible after first-in-human analysis

      Results of the first-in-human analysis of acute interactions and healing process after flow diverter implantation using optical coherence tomography (OCT) imaging was presented by Boris Pab ón and Juan Mejia as members of Angioteam, Angiodinamia, Clinica Del Norte, Medellín, Colombia, at the 15 th Congress of the World Federation of Interventional and Therapeutic Neuroradiology (WFITN; 21–24 October 2019, Naples, Italy). Having evaluated three patients at the time of presentation, Pabón said: “The ultimate objective was to evaluate the feasibility and success of OCT technology after deploying dual layer flow diverter stents intracranially and extracranially, and to describe ...

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      Mentions: Gentuity

    2. Noise reduction in optical coherence tomography images using a deep neural network with perceptually-sensitive loss function

      Explore OSA | OSA Publishing
      Noise reduction in optical coherence tomography images using a deep neural network with perceptually-sensitive loss function

      Optical coherence tomography (OCT) is susceptible to the coherent noise, which is the speckle noise that deteriorates contrast and the detail structural information of OCT images, thus imposing significant limitations on the diagnostic capability of OCT. In this paper, we propose a novel OCT image denoising method by using an end-to-end deep learning network with a perceptually-sensitive loss function. The method has been validated on OCT images acquired from healthy volunteers’ eyes. The label images for training and evaluating OCT denoising deep learning models are images generated by averaging 50 frames of respective registered B-scans acquired from a region with ...

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      Mentions: University of Erlangen Gangjun Liu Peking University

    3. High-throughput dark-field full-field optical coherence tomography

      Explore OSA | OSA Publishing
      High-throughput dark-field full-field optical coherence tomography

      Full-field optical coherence tomography (FF-OCT) can rapidly acquire 2D en face OCT images through a scattering medium. However, the standard interferometer configurations waste almost 75% of light. In addition, specular reflections can saturate the detector, limiting FF-OCT performance. Here, we report on a high-throughput dark-field (HTDF) FF-OCT configuration that efficiently uses the available light budget and allows suppressing specular reflections. Specifically, we demonstrate that images acquired with the HTDF FF-OCT system have 3.5 times higher signal-to-noise ratio when compared to our previously developed regular FF-OCT system.

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      Mentions: Claude Boccara ESPCI ParisTech Egidijus Auksorius

    4. Optical rotary junction incorporating a hollow shaft DC motor for high-speed catheter-based optical coherence tomography

      Explore OSA | OSA Publishing Probes
      Optical rotary junction incorporating a hollow shaft DC motor for high-speed catheter-based optical coherence tomography

      In intravascular optical coherence tomography (OCT), the optical rotary junction plays an important role in rotating and pulling back the catheter to generate cross-sectional coronary artery images. To meet the requirements of high-speed intravascular OCT in a clinical setting, the rotary junction should generate high torque and low vibration. In this Letter, we demonstrate an ultrahigh speed optical rotary junction incorporating a hollow shaft brushless DC servomotor to remove a pulley belt, or a gear to minimize vibration noise and transfer stable torque. To evaluate the performance of the rotary junction, the vibration noise and variation of rotation were measured ...

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    5. Beyond Fourier transform: break the axial resolution limit in optical coherence tomography

      Explore arxiv.org
      Beyond Fourier transform: break the axial resolution limit in optical coherence tomography

      Optical coherence tomography (OCT) is a volumetric imaging modality that empowers the clinicians and scientists to noninvasively visualize and examine the microscopic cross-sectional architectures of biological samples. By taking advantages of the coherence gating, OCT could achieve micrometer-level axial sectioning with high sensitivity. In the past decade, substantial efforts have been made to push the axial resolution of Fourier-domain OCT (FD-OCT) further into the sub-micron regime via physically extending the system’s spectral bandwidth. Here, we would like to offer a new perspective on this problem. We argue that the coupling between the axial resolution and the spectral bandwidth in ...

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      Mentions: University of Alabama Singapore Eye Research Institute Nanyang Technological University

    6. Resolving absolute depth in circular-ranging optical coherence tomography by using a degenerate frequency comb

      Explore OSA | OSA Publishing Tunable Sources
      Resolving absolute depth in circular-ranging optical coherence tomography by using a degenerate frequency comb

      In Fourier-domain optical coherence tomography, an interference signal is generated that spans an RF bandwidth proportional to the product of three parameters: the imaging range, the imaging speed, and the inverse of the axial resolution. Circular-ranging optical coherence tomography (CR-OCT) architectures were introduced to ease long-range imaging by decoupling the imaging range from the signal RF bandwidth. As a consequence, present CR-OCT systems resolve the relative, but not the absolute, depth location of the scatterers. We introduce here a modified implementation of CR-OCT that uses a degenerate frequency comb source that allows recovery of absolute depth information while only minimally ...

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      Mentions: Massachusetts General Hospital Harvard University Benjamin J. Vakoc

    7. Frequency-domain optical coherence tomography system in the terahertz region

      Explore Home - Springer NDE/NDT , Other Non-Medical
      Frequency-domain optical coherence tomography system in the terahertz region

      In this study, a frequency-domain optical coherence tomography (FD-OCT) system in the terahertz frequency range was developed. To generate tunable continuous-wave terahertz radiation, the outputs of two near-infrared external cavity diode lasers were mixed in an antenna-coupled photo-mixer. Using the FD-OCT system, tomographic profiling of the front and back surfaces of a high-resistivity silicon plate was realized.

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      Mentions: Osaka University

    8. CPT codes for home OCT established

      Explore Optical Coherence Tomography News Ophthalmology , Other Business News
      CPT codes for home OCT established

      The AMA’s CPT® Editorial Panel has accepted three new category III codes for reporting patient-initiated remote retinal OCT scans, facilitated by Notal Vision’s home-based OCT pipeline technology Notal Vision, Inc., a privately held ophthalmic diagnostic services company focused on advancing eye care with precision medicine by extending disease management from the clinic to the home, announced today that the American Medical Association’s (AMA) Current Procedural Terminology (CPT) Editorial Panel has established three new Category III codes (0604T, 0605T, 0606T) to report patient-initiated remote retinal optical coherence tomography (OCT) scans, which is performed using Notal Vision’s home-based ...

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      Mentions: Kester Nahen Notal Vision

    9. Identification of Fungus-infected Tomato Seeds Based on Full-Field Optical Coherence Tomography

      Explore OSA | OSA Publishing NDE/NDT , Other Non-Medical
      Identification of Fungus-infected Tomato Seeds Based on Full-Field Optical Coherence Tomography

      The morphological changes of anthracnose (fungus) -infected tomato seeds have been studied to identify the infection and characterize its effect. Full-field optical coherence tomography (FF-OCT) has been utilized as a nondestructive but efficient modality for visualizing the effects of fungal infection. The cross-sectional images extracted from a stack of en face FF-OCT images showed significant changes with infection in the seed structure. First of all, the seed coat disappeared with the infection. The thickness of the seed coat of a healthy seed was measured as 28.2 µm, with a standard deviation of 1.2 µm. However, for infected seeds ...

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      Mentions: Byeong Ha Lee Gwangju Institute of Science and Technology

    10. PhotoniCare Announces FDA Clearance for First-In-Class Technology for Imaging the Ear

      Explore Optical Coherence Tomography News Otolaryngology , Clinical Trials , Other Business News
      PhotoniCare Announces FDA Clearance for First-In-Class Technology for Imaging the Ear

      PhotoniCare, Inc., a company dedicated to revolutionizing healthcare by providing physicians with better diagnostic tools, today announced that the U.S. Food & Drug Administration (FDA) has granted 510(k) clearance for its TOMi ™ Scope for non-invasive imaging of the middle ear. Using optical coherence tomography (OCT) high resolution depth imaging, TOMi Scope helps to determine the presence or absence of fluid in the middle ear and to characterize the fluid type. According to clinical guidelines, the presence of fluid in the middle ear is a primary indicator for determining infection. Designed to eliminate subjectivity and speculation, TOMi Scope allows physicians ...

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      Mentions: Ryan L. Shelton PhotoniCare

    11. The year in cardiology: acute coronary syndromes: The year in cardiology 2019

      Explore Journals Cardiology
      The year in cardiology: acute coronary syndromes: The year in cardiology 2019

      The mechanisms and the pathologic substrate of plaque erosion and plaque fissure are different. Indeed, plaques complicated by erosion tend to be matrix-rich, lipid-poor, and usually lack prominent macrophage collections, unlike plaques that rupture, which characteristically have thin fibrous caps, large lipid pools, and abundant foam cells. 9 In a prospective study in 211 patients with STEMI who underwent pre-intervention optical coherence tomography (OCT) examination for the culprit lesion, Tan et al . 10 found that trimethylamine N-oxide (TMAO) levels, a gut microbiota-dependent metabolite derived from dietary phosphatidylcholine and choline, were significantly and independently higher in patients with plaque fissure than ...

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      Mentions: Imperial College London Oxford University Thomas F. Luscher

    12. Interferometer-in-Spectrometer for High-Resolution Optical Coherence Tomography

      Explore Hindawi Publishing Corporation
      Interferometer-in-Spectrometer for High-Resolution Optical Coherence Tomography

      Ultrahigh-resolution optical coherence tomography provides an axial resolution of 1-2  μ m for resolving cellular structures of biological tissues critical for the diagnosis of diseases. However, it requires a relatively large spectral bandwidth which is not supported by the key components of the imaging system. We propose a novel spectral-domain OCT design, termed interferometer-in-spectrometer, which is able to compensate the bandwidth limitations of the grating and the line scan sensor by spectral shaping without compromising the signal intensity and adding the system cost. The advantage of axial resolution and ranging depth over the standard design is experimentally validated using the standard ...

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      Mentions: Nanyang Technological University Linbo Liu
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  2. Recent Articles From Around The Web

    1. Stress, anxiety, harassment: huge survey reveals pressures of scientists’ working lives

      Explore Nature Publishing Group
      Stress, anxiety, harassment: huge survey reveals pressures of scientists’ working lives

      Global study highlights long hours, poor job security and mental-health struggles. A survey of more than 4,000 scientists has painted a damning picture of the culture in which they work, suggesting that highly competitive and often hostile environments are damaging the quality of research. Around 80% of the survey’s participants — mostly academic researchers in the United Kingdom — believed that competition had fostered mean or aggressive working conditions, and half described struggles with depression or anxiety. Nearly two-thirds of respondents reported witnessing bullying or harassment and 43% said they had experienced it. “These results paint a shocking portrait of ...

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    2. Widefield Swept Source OCTA in Retinitis Pigmentosa

      Explore MDPI Open Access Journals Platform Ophthalmology
      Widefield Swept Source OCTA in Retinitis Pigmentosa

      1) Background: To evaluate superficial capillary plexus (SCP), deep capillary plexus (DCP), choriocapillaris (CC), perfusion density (PD), and vessel length density (VLD) in macular and near/mid periphery regions in patients with retinitis pigmentosa (RP) using widefield swept source optical coherence tomography angiography (WSS-OCTA). (2) Methods: Twelve RP patients (20 eyes) and 20 age-matched subjects (20 eyes) were imaged with the SS-OCTA system (PLEX Elite 9000, Carl Zeiss Meditec Inc., Dublin, CA, USA). Quantitative analysis was performed in the macular and peripheral regions. The main outcome measures were SCP, DCP, CC, PD, and VLD in central and peripheral areas. (3 ...

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    3. Anterior segment optical coherence tomographic characterisation of keratic precipitate

      Explore ScienceDirect Ophthalmology
      Anterior segment optical coherence tomographic characterisation of keratic precipitate

      Background/objectives Anterior segment optical coherence tomography (AS-OCT) can be used to visualise keratic precipitates (KPs) on the corneal endothelium. However, there has been no correlation between characteristic clinical appearances of KPs and AS-OCT morphology. We wished to assess the potential diagnostic role of AS-OCT in patients presenting with inflammatory eye disease and KPs. Subjects/methods Six patients with inflammatory KPs were compared to one patient with infective interface keratitis following Descemet Membrane Endothelial Keratoplasty (DMEK) and one patient with endothelial pigment. AS-OCT was performed in each case and morphological features of the KPs were compared. Reflectivity of KPs was ...

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    4. Vascular changes with optical coherence tomography angiography during aura of migraine: A case report

      Explore SAGE Journals Neurology , Ophthalmology
      Vascular changes with optical coherence tomography angiography during aura of migraine: A case report

      Purpose: To demonstrate macular and optic disk vessel changes by optical coherence tomography angiography during and after a migraine attack with aura Methods: Case report Results: A 34-year-old healthy female patient was evaluated by optical coherence tomography angiography imaging during visual aura with phosphenes in the left visual field. Optical coherence tomography angiography imaging showed diffuse narrowing of the retinal vessels, decreased radial peripapillary capillary density, and decreased superficial and deep foveal vessel density in the right eye. These changes improved 3 hours after visual aura. The patient suffered from right eye pain and right-sided headache, which are typical for ...

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    5. Numerical method for axial motion artifact correction in retinal spectral-domain optical coherence tomography

      Explore Home - Springer Ophthalmology
      Numerical method for axial motion artifact correction in retinal spectral-domain optical coherence tomography

      A numerical method that compensates image distortions caused by random fluctuations of the distance to an object in spectral-domain optical coherence tomography (SD OCT) has been proposed and verified experimentally. The proposed method is based on the analysis of the phase shifts between adjacent scans that are caused by micrometer-scale displacements and the subsequent compensation for the displacements through phase-frequency correction in the spectral space. The efficiency of the method is demonstrated in model experiments with harmonic and random movements of a scattering object as well as during in vivo imaging of the retina of the human eye.

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      Mentions: Nizhny Novgorod State Medical Academy Institute of Applied Physics Grigory V. Gelikonov

    6. OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN PATIENTS WITH RETINITIS PIGMENTOSA–ASSOCIATED CYSTOID MACULAR EDEMA

      Explore LWW Online Ophthalmology
      OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN PATIENTS WITH RETINITIS PIGMENTOSA–ASSOCIATED CYSTOID MACULAR EDEMA

      Purpose: To investigate the microstructure of cystoid macular edema (CME) in retinitis pigmentosa (RP) and the associated vascular changes using optical coherence tomography (OCT) angiography. Methods: In this retrospective study, we included 42 eyes of 21 patients with RP and age-similar normally sighted controls who underwent both OCT and optical coherence tomography angiography . Using OCT, spatial distribution of CME and the retinal layer, which CME located, was examined. Optical coherence tomography angiography images of the superficial capillary plexus and deep capillary plexus were obtained. Foveal and parafoveal flow densities in each layer and foveal avascular zone area were measured. Results ...

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      Mentions: Young H. Yoon University of Ulsan

    7. Optical coherence tomography angiography in diabetes: A review

      Explore SAGE Journals Ophthalmology
      Optical coherence tomography angiography in diabetes: A review

      Diabetic retinopathy is a common diabetes complication representing a heavy burden in terms of visual impairment and heath expenditure. Optical coherence tomography angiography is a relatively new imaging method and has proven to be a powerful tool in the analysis of diabetic retinopathy common features, including microaneurysms, intraretinal microvascular abnormalities, or neovascularization, as well as in research field, challenging the gold standard of fluorescein angiography. Many studies underlined the vascular impairment observed through optical coherence tomography angiography and its typical parameters such as vessel length density, foveal avascular zone, and fractal dimension. Choriocapillaris involvement in the pathogenesis of diabetic retinopathy ...

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      Mentions: Giuseppe Querques Francesco Bandello Università Vita-Salute San Raffaele

    8. ATTENUATION OUTER RETINAL BANDS ON OPTICAL COHERENCE TOMOGRAPHY FOLLOWING MACULAR EDEMA: A Possible Manifestation of Photoreceptor Misalignmen

      Explore LWW Online Ophthalmology

      Purpose: Macular edema is a common retinal disease which may leave important anatomical and functional sequelaes. Directional fundus imaging consists of comparing on- and off-axis images to reveal angle-dependent reflectance properties of fundus structures, which may be related to misaligned photoreceptors . Here, we analyzed directional optical coherence tomography (OCT) and flood-illumination adaptive optics ophthalmoscopy images to detect evidence of misaligned photoreceptors following macular edema . Methods: Transversal, observational study. Nine patients having recovered a normal macular profile after macular edema due to retinal vein occlusion were included. For each patient, a reference OCT scan (i.e., with the incident beam normal ...

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      Mentions: Michel Pâques Kate Grieve

    9. Quantification of Retinal Nerve Fibre Layer Thickness on Optical Coherence Tomography with a Deep Learning Segmentation-Free Approach

      Explore Nature Publishing Group Ophthalmology
      Quantification of Retinal Nerve Fibre Layer Thickness on Optical Coherence Tomography with a Deep Learning Segmentation-Free Approach

      This study describes a segmentation-free deep learning (DL) algorithm for measuring retinal nerve fibre layer (RNFL) thickness on spectral-domain optical coherence tomography (SDOCT). The study included 25,285 B-scans from 1,338 eyes of 706 subjects. Training was done to predict RNFL thickness from raw unsegmented scans using conventional RNFL thickness measurements from good quality images as targets, forcing the DL algorithm to learn its own representation of RNFL. The algorithm was tested in three different sets: (1) images without segmentation errors or artefacts, (2) low-quality images with segmentation errors, and (3) images with other artefacts. In test set 1 ...

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      Mentions: UCSD Felipe A. Medeiros

    10. Optical coherence tomography of the retina in schizophrenia: Inter-device agreement and relations with perceptual function

      Explore ScienceDirect Neurology , Ophthalmology
      Optical coherence tomography of the retina in schizophrenia: Inter-device agreement and relations with perceptual function

      Background Optical coherence tomography (OCT) studies have demonstrated differences between people with schizophrenia and controls. Many questions remain including the agreement between scanners. The current study seeks to determine inter-device agreement of OCT data in schizophrenia compared to controls and to explore the relations between OCT and visual function measures. Methods Participants in this pilot study were 12 individuals with schizophrenia spectrum disorders and 12 age- and sex-matched controls. Spectralis and Cirrus OCT machines were used to obtain retinal nerve fiber layer (RNFL) thickness and macular volume. Cirrus was used to obtain ganglion cell layer + inner plexiform layer (GCL + IPL ...

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      Mentions: Laura J. Balcer

    11. Correlation of Microvascular Ophthalmic Disease With Macrovascular Coronary Artery Disease in Trinidad

      Explore Home - ClinicalTrials.gov Cardiology , Clinical Trials
      Correlation of Microvascular Ophthalmic Disease With Macrovascular Coronary Artery Disease in Trinidad

      Coronary artery disease (CAD) is the leading cause of death in Trinidad and Tobago. Early detection and management can help improve morbidity and mortality. Retinal artery microvascular disease has been shown to directly correlate with coronary artery disease. Retinal artery calibre screening via the Optic Coherence Tomography (OCT) will provide a non-invasive method of diagnosing CAD.

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    12. Mechanical test study in composites using digital holographic interferometry and optical coherence tomography simultaneously

      Explore OSA | OSA Publishing NDE/NDT
      Mechanical test study in composites using digital holographic interferometry and optical coherence tomography simultaneously

      A dual optical configuration to inspect the internal and external mechanical response of a composite specimen is presented. The inspection simultaneously uses two equally aligned optical techniques, digital holographic interferometry and Fourier domain optical coherence tomography, to retrieve surface and internal data, respectively. The sample under study is a composite specimen of poly-methyl-methacrylate reinforced with metallic particles. Two different sets of samples are analyzed to compare their mechanical behavior. A homemade, fully controlled testing machine is used to apply a controlled compression load while each technique registers an image. In this form, the surface and internal optical phase measurements are ...

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    13. Retinal Nerve Fiber Layer Thickness and Total Macular Volume in Multiple Sclerosis Subtypes and Their Relationship with Severity of Disease, a Cross-Sectional Study

      Explore Medical Journals Publisher Neurology , Ophthalmology
      Retinal Nerve Fiber Layer Thickness and Total Macular Volume in Multiple Sclerosis Subtypes and Their Relationship with Severity of Disease, a Cross-Sectional Study

      Background: Optic neuritis (ON) is an inflammatory demyelinating lesion in the optic nerve, which is strongly associated with multiple sclerosis (MS). Optical coherence tomography (OCT) is a noninvasive technique for the evaluation of the retinal layers. Our aim was to examine OCT metrics including retinal nerve fiber layer thickness (RNFLT), and total macular volume (TMV), in MS subtypes and their relationship with duration, first manifestation, and severity of disease. Material and Methods: In this cross-sectional study, patients with a definite diagnosis of MS underwent complete ophthalmic and neurologic examination. OCT parameters including TMV and RNFLT were compared between MS subtypes ...

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    14. Noninvasive optical coherence tomography imaging correlates with anatomic and physiologic end-organ changes in healthy normotensives with systemic blood pressure variability

      Explore LWW Online Cardiology
      Noninvasive optical coherence tomography imaging correlates with anatomic and physiologic end-organ changes in healthy normotensives with systemic blood pressure variability

      Objective Blood pressure variability (BPV) is considered as a novel risk factor for cardiovascular disease including left ventricular hypertrophy, vascular stiffness, and renal dysfunction. In this study, we aimed to determine the relationship between ambulatory BPV with subclinical organ damage and vascular stiffness parameters in normotensive healthy subjects. Methods A total of 100 healthy subjects over 18 years of age were included in this cross-sectional study. We divided the participants into two groups according to the median value of the SD of mean 24-h blood pressure (BP) (Group 1: SD of mean 24-h BP <10.15 and Group 2: SD ...

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      Mentions: Duke University

    15. OCT Angiography Features of Neovascularization as Predictive Factors for Frequent Recurrence in Age-Related Macular Degeneration

      Explore American Journal of Ophthalmology Ophthalmology
      OCT Angiography Features of Neovascularization as Predictive Factors for Frequent Recurrence in Age-Related Macular Degeneration

      Purpose To investigate the features of neovascularization (NV) in eyes with neovascular age-related macular degeneration (NVAMD) using optical coherence tomography angiography (OCTA) according to the treatment interval of intravitreal aflibercept injection (IVI). Design Retrospective, interventional, comparative case series. Methods Patients with type 1 NV treated with the “pro-re-nata” regimen after three loading IVI were classified into two groups based on the numbers of treatments during 12 months, specifically a stable group who required less than two injections and an unstable group who required more than three injections. Quantitative features of OCTA including NV area, NV length, NV density, endpoint density ...

      Read Full Article
      16. See all articles
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  9. Picture Gallery

    Use of optical coherence tomography deemed feasible after first-in-human analysis Noise reduction in optical coherence tomography images using a deep neural network with perceptually-sensitive loss function High-throughput dark-field full-field optical coherence tomography Optical rotary junction incorporating a hollow shaft DC motor for high-speed catheter-based optical coherence tomography Beyond Fourier transform: break the axial resolution limit in optical coherence tomography Resolving absolute depth in circular-ranging optical coherence tomography by using a degenerate frequency comb Frequency-domain optical coherence tomography system in the terahertz region CPT codes for home OCT established Identification of Fungus-infected Tomato Seeds Based on Full-Field Optical Coherence Tomography PhotoniCare Announces FDA Clearance for First-In-Class Technology for Imaging the Ear The year in cardiology: acute coronary syndromes: The year in cardiology 2019 Interferometer-in-Spectrometer for High-Resolution Optical Coherence Tomography

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  12. Recent Quotes

    1. This milestone marks the first step towards establishing physician and patient reimbursement for our home OCT pipeline technology...We applaud the AMA’s CPT Editorial panel for establishing codes for billing remote diagnostic services and patient home monitoring services. We believe that a home-based OCT will be the future of monitoring patients with wet AMD, one that allows doctors to individualize their patients’ treatment.
      By Kester Nahen
    2. We hope that this new lab between SNEC-SERI and NTU will be the start of an important programme to utilise engineering solutions to help and improve care of our patients with eye problems.
      By Tin Aung
    3. “At PhotoniCare we set out to solve the massive problem of frequent misdiagnosis of middle ear infections, and the overuse of antibiotics and referrals to surgery in children that result...We thank the FDA for clearing our TOMi Scope under a new product code unique to our technology, and look forward to bringing this innovation to doctors and patients very soon.”
      By Ryan L. Shelton
    4. The move to the new office space on Fox Drive has been exciting, to say the least...Part of the move includes a build out of a portion of the office space. So the #EnginEarGuys got to try our hand at interior design! Much of the design, however, was spearheaded by one of PhotoniCare’s engineers, Heather Howard. She helped the team navigate the moving process and make decisions on everything from our new manufacturing layout to the aesthetics – carpet, paint, and furniture!
      By Ryan L. Shelton
    5. “Our group has spent quite a few years working on developing the underlying imaging technology...This grant will support our translational efforts and allow us to identify ophthalmic surgeries that will directly benefit from real-time guidance and to better understand how surgical maneuvers impact postoperative visual function.
      By Yuankai K. Tao
    6. An historic issue with OCT is that the depth resolution is typically several times better than the lateral resolution...If the layers of imaged tissues happen to be horizontal, then they're well defined in the scan. But to extend the full power of OCT for live imaging of tissues throughout the body, a method for overcoming the tradeoff between lateral resolution and depth of imaging was needed.
      By Joseph A. Izatt
    7. With advances in microscopy techniques such as ours, we hope to change the way we detect, visualize and monitor diseases that will lead to better diagnosis, treatments and outcomes.
      By Stephen A. Boppart
    8. We’ve done a lot of benchtop imaging with micro-OCT, but this is the first time we’ve been able to use it in people...It’s unprecedented to see this pathophysiology dynamically in living patients. It will allow us to begin to understand things we never even knew were there.
      By Guillermo J. Tearney
    9. I’m so proud of the team here at NinePoint,...Our group over the years has really pushed the limits of engineering innovation to help patients. This past year has been especially fruitful, with the clearance and market launch of a first-of-its-kind artificial intelligence technology, and now with the clearance of a pancreatico-biliary application for the Low-Profile Optical Probe. The ability to promote to this new anatomical space really strengthens the platform of the NvisionVLE Imaging System, and continues to build the opportunity for this technology to help patients.
      By Eman Namati
    10. Imaging is more accurate, helps guide decisions and facilitates tailored therapy, especially in younger heart attack patients who more frequently have plaque erosion or non-atherosclerotic coronary artery disease.
      By Giulio Guagliumi