Recent Articles From Around The Web

1. Distortion and Instability Compensation with Deep Learning for Rotational Scanning Endoscopic Optical Coherence Tomography

   Explore ScienceDirect 22 min ago Probes

   

   Optical Coherence Tomography (OCT) is increasingly used in endoluminal procedures since it provides high-speed and high resolution imaging. Distortion and instability of images obtained with a proximal scanning endoscopic OCT system are significant due to the motor rotation irregularity, the friction between the rotating probe and outer sheath and synchronization issues. On-line compensation of artefacts is essential to ensure image quality suitable for real-time assistance during diagnosis or minimally invasive treatment. In this paper, we propose a new online correction method to tackle both B-scan distortion, video stream shaking and drift problem of endoscopic OCT linked to A-line level image ...

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2. Laser-induced choroidal neovascularization detected on optical coherence tomography angiography in patients with diabetic retinopathy

   Explore ScienceDirect 26 min ago Ophthalmology

   

   Purpose To report two cases of laser-induced choroidal neovascularization (CNV) using swept source optical coherence tomography (SS-OCTA) imaging in patients with proliferative diabetic retinopathy. Observations Two patients developed CNV adjacent to laser scars, and these neovascular lesions were detected on SS-OCTA imaging. Historically, both patients had subretinal fluid associated with these lesions. Visual acuity for both patients was 20/25 in the affected eyes. Both patients were observed over multiple years with stable CNV and visual acuity. Conclusions and importance SS-OCTA was able to detect laser-induced CNV in a rapid and non-invasive manner. When there is no foveal involvement and ...

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   Mentions: University of Miami

3. Optical coherence tomography- angiography: A new diagnostic and follow-up tool for glaucoma

   Explore Internet Archive Scholar 34 min ago Ophthalmology

   

   Glaucoma is an optic neuropathy and is one of the leading causes of irreversible vision loss worldwide. There are studies on the role of vascular dysfunction in the pathogenesis of glaucoma. Evaluation of intraocular blood flow will be useful in elucidating the pathogenesis. Various techniques are available for the diagnosis and follow-up of patients with glaucoma. Optical coherence tomography angiography (OCTA) has emerged as a new technology to detect the vascular effects of the glaucoma. Optical coherence tomography angiography (OCTA) is a new technology and many publications have been made in the field of glaucoma. In this article, we aimed ...

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4. Corneal Irregular Astigmatism And Visual Function On Anterior Segment Optical Coherence Tomography In TGFBI Corneal Dystrophy

   Explore assets.researchsquare.com 1 hour, 3 min ago Ophthalmology

   

   The purpose of this study was to evaluate corneal irregular astigmatism of patients with granular and lattice corneal dystrophy (GCD and LCD). 70 GCD, 35 LCD, and 23 control eyes were included. Anterior and posterior corneal topographic data obtained from anterior segment optical coherence tomography were expanded into four components via Fourier harmonic analysis. These components were compared with healthy eyes and the association between each component and best-corrected visual acuity (BCVA) was investigated. Anterior and posterior components increased in LCD eyes, but none increased in GCD. Posterior components of GCD type 2 (GCD2), anterior and posterior of LCD type ...

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   Mentions: University of Tokyo

5. Early-term Optical Coherence Tomography Angiographic Findings in Pediatric Patients Infected with COVID-19

   Explore Taylor & Francis Online 5 hours, 29 min ago Ophthalmology

   

   Purpose: The aim of this study was to investigate possible vascular changes in pediatric patients infected with COVID-19 and to compare these with an age-matched control group. Methods: All patients underwent an ocular assessment and optical coherence tomography angiography examination. Two vascular networks were analyzed as the superficial and deep regions. Results: Evaluation was made of 40 eyes of 20 patients who had recently recovered from COVID infection and 80 eyes of 40 healthy individuals. The DCP-VD values of the COVID group were significantly lower than the control group in most quadrants. The FAZ PERIM and FAZ area values in ...

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6. Integrated deep learning framework for accelerated optical coherence tomography angiography

   Explore Nature Publishing Group 6 hours, 33 min ago Ophthalmology

   

   Label-free optical coherence tomography angiography (OCTA) has become a premium imaging tool in clinics to obtain structural and functional information of microvasculatures. One primary technical drawback for OCTA, however, is its imaging speed. The current protocols require high sampling density and multiple acquisitions of cross-sectional B-scans to form one image frame, resulting in low acquisition speed. Recently, deep learning (DL)-based methods have gained attention in accelerating the OCTA acquisition process. They achieve faster acquisition using two independent reconstructing approaches: high-quality angiograms from a few repeated B-scans and high-resolution angiograms from undersampled data. While these approaches have shown promising results ...

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7. The utility of wide-field optical coherence tomography angiography in diagnosis and monitoring of proliferative diabetic retinopathy in pregnancy

   Explore ScienceDirect 19 hours, 40 min ago Ophthalmology

   

   Diabetic retinopathy is an increasingly common complication of diabetes mellitus that benefits from early diagnosis and frequent monitoring, especially in pregnancy where there is a greater risk of progression. Fundus fluorescein angiography is currently the gold standard method of investigation for neovascularization. However, this has risks of unpleasant and potentially dangerous side effects, with an added theoretical risk to the fetus in pregnancy. Wide-field optical coherence tomography angiography (PLEX Elite 9000, Carl Zeiss Meditec, Inc. USA and DRI Swept Source OCT Triton, Topcon Medical Systems, Inc. USA) potentially offers a safer, faster and equally effective alternative method for diagnosis and ...

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   Mentions: University College London Topcon Medical Systems Carl Zeiss Meditec

8. Automatic Assessment of Calcified Plaque and Nodule by Optical Coherence Tomography Adopting Deep Learning Mode

   Explore SPIE Digital Library 20 hours, 4 min ago Cardiology

   

   Significance: Detection and characterization of coronary atherosclerotic plaques often need reviews of a large number of optical coherence tomography (OCT) imaging slices to make a clinical decision. However, it is a challenge to manually review all the slices and consider the interrelationship between adjacent slices. Approach : Inspired by the recent success of deep convolutional network on the classification of medical images, we proposed a ResNet-3D network for classification of coronary plaque calcification in OCT pullbacks. The ResNet-3D network was initialized with a trained ResNet-50 network and a three-dimensional convolution filter filled with zeros padding and non-zeros padding with a convolutional ...

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   Mentions: University of Queensland

9. Capillary density and caliber as assessed by optical coherence tomography angiography may be significant predictors of diabetic retinopathy severity

   Explore Journals | PLOS Jan 26 2022 Ophthalmology

   

   Purpose To validate retinal capillary density and caliber associations with diabetic retinopathy (DR) severity in different clinical settings. Methods This cross-sectional study assessed retinal capillary density and caliber in the superficial retinal layer of 3-mm OCTA scans centered on the fovea. Images were collected from non-diabetic controls and subjects with mild or referable DR (defined DR worse than mild DR) between February 2016 and December 2019 at secondary and tertiary eye care centers. Vessel Skeleton Density (VSD), a measure of capillary density, and Vessel Diameter Index (VDI), a measure of vascular caliber, were calculated from these images. Discriminatory performance of ...

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   Mentions: Johns Hopkins University National Institutes of Health University of Southern California

10. Idiopathic Epiretinal Membrane: Microvasculature Analysis with Optical Coherence Tomography and Optical Coherence Tomography Angiography

    Explore MDPI Open Access Journals Platform Jan 26 2022 Ophthalmology

    

    Background: The present study examined the relationships among macular microvasculature, retinal structure, and epiretinal membrane (ERM) and explored the utility of optical coherence tomography (OCT) angiography (OCTA) in idiopathic ERM assessment. Methods: The study sample comprised 276 eyes of 276 patients. A total of 154 eyes with ERM and 122 normal (control) eyes were analyzed. Only one eye of each participant was randomly selected for posterior segment imaging. Each patient underwent OCT and OCTA. Images were analyzed with AngioTool 0.6. Results: Foveal avascular zone was significantly smaller in the ERM group ( p = 0.044). Average retinal thickness and foveal ...

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11. Neuro-ophthalmological evaluation including optical coherence tomography surrounding venous sinus stenting in idiopathic intracranial hypertension with papilledema: a case series

    Explore Home - Springer Jan 26 2022 Ophthalmology

    

    Venous sinus stenting (VSS) for idiopathic intracranial hypertension (IIH) has been demonstrated to achieve significant symptom improvement while harboring a low periinterventional morbidity profile. Comprehensive neuro-ophthalmological monitoring represents a cornerstone of disease monitoring. The value of optical coherence tomography (OCT) requires further exploration. Patients with IIH and papilledema who underwent VSS between 04/2018 and 02/2021 were retrospectively reviewed. Clinical and radiological were analyzed. Neuro-ophthalmological data included visual acuity, visual fields, fundoscopy categorized via Frisén scale, and OCT obtained retinal nerve fiber layer (RNFL) thickness were analyzed. Of 39 IIH patients who underwent cerebral angiography with transverse-sigmoid sinus ...

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12. Association of prediabetes with retinal microvasculature on swept-source optical coherence tomography angiography in the elderly

    Explore LWW Online Jan 26 2022 Ophthalmology

    

    Aims: To investigate the retinal microvasculature in the elderly persons with prediabetes mellitus (preDM) and type 2 DM. Methods: This cross-sectional study included a total of 452 eyes without retinal pathologies of 301 elderly volunteers aged ≥65 years, and they were categorized into nonDM (225 eyes), preDM (177 eyes), and DM (50 eyes) groups based on their HbA1c. Fundus photography, swept-source optical coherence tomography and angiography, and comprehensive systemic examinations were conducted. Vessel density (VD) and foveal avascular zone (FAZ) in superficial and deep retinal microvasculature were investigated for their association with DM stages using linear mixed model. Results: Superficial ...

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    Mentions: University of Tokyo

13. The Role of Optical Coherence Tomography Angiography in Detecting and Monitoring Inflammatory Choroidal Neovascularization

    Explore LWW Online Jan 26 2022 Ophthalmology

    

    Purpose: To investigate the utility of optical coherence tomography angiography (OCTA) for the detection of inflammatory choroidal neovascularization (iCNV) and monitoring their response to treatment. Methods: A retrospective review of patients with a diagnosis of uveitis and associated iCNV with active exudation was performed. Active iCNV was determined by spectral domain-OCT and/or fluorescein angiogram. Spectral domain-OCTA outer retina to choriocapillaris (ORCC) slabs were evaluated for the presence of iCNV. Follow-up OCTA images were qualitatively assessed to determine if regression of iCNV occurred following treatment. Results: Thirteen eyes of 12 patients were included. The etiologies of uveitis included punctate inner ...

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14. Pachychoroid spectrum disease and choriocapillary flow analysis in patients with Cushing disease: an optical coherence tomography angiography study

    Explore Home - Springer Jan 26 2022 Ophthalmology

    

    Purpose: To investigate the presence of pachychoroid spectrum disease (PSD) in patients with Cushing disease (CD) and to evaluate subfoveal choroidal thickness (SFCT) and choriocapillary flow using spectral domain OCT (SD-OCT) with the enhanced depth imaging (EDI) and optical coherence tomography angiography (OCT-A). Methods: Thirty-two patients with CD and 32 age- and sex-matched healthy volunteers were enrolled in this observational study. All participants had a complete ophthalmic examination including SD-OCT with EDI and OCT-A, and were subjected to the Perceived Stress Scale test (PSS). All patients with CD had hormone test including 24-h urinary-free cortisol (UFC) and plasma adrenocorticotropic hormone ...

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15. Optical Coherence Tomography Angiography in Diabetic Patients: A Systematic Review

    Explore MDPI Open Access Journals Platform Jan 26 2022 Ophthalmology

    

    Background: Diabetic retinopathy (DR) is the leading cause of legal blindness in the working population in developed countries. Optical coherence tomography (OCT) angiography (OCTA) has risen as an essential tool in the diagnosis and control of diabetic patients, with and without DR, allowing visualisation of the retinal and choroidal microvasculature, their qualitative and quantitative changes, the progression of vascular disease, quantification of ischaemic areas, and the detection of preclinical changes. The aim of this article is to analyse the current applications of OCTA and provide an updated overview of them in the evaluation of DR. Methods: A systematic literature search ...

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