1. Recent Articles From Around The Web

    1. Topcon Announces Date for 3rd Annual ISSOCT Conference

      Topcon Announces Date for 3rd Annual ISSOCT Conference

      Leading International Swept Source OCT Meeting to Be Held in the U.S. in February 2019 Topcon Medical Systems (TMS) of Oakland, NJ is pleased to announce that the 3rd Annual ISSOCT Conference will be held on February 10-11, 2019 at the Sanibel Harbour Marriott Resort in Fort Myers, Florida, USA. Join the world’s leading ophthalmologists as they present new clinical findings made possible with Swept Source Imaging and OCT Angiography.1 The 2nd ISSOCT Conference, which was held recently in Paris, France, was attended by over 420 delegates from 46 countries. The scientific program, designed by Richard F ...

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    2. Detect Diabetic Retinopathy Earlier with OCT-A

      Detect Diabetic Retinopathy Earlier with OCT-A

      Routine screening could change the standard of care. A new study found screening diabetes patients with optical coherence tomography angiography (OCT-A) could uncover early microvascular changes that may help clinicians intervene sooner to avoid the development of diabetic retinopathy (DR). 1 Researchers at the Vanderbilt Eye Institute studied 37 eyes of 20 patients with diabetes, none of whom showed signs of DR upon clinical and dilated exam by a retina specialist. Subjects had a mean glycated hemoglobin A1c of 7.2%. After assessing vessel density, flow area and foveal avascular zone size with OCT-A, the researchers discovered 15 eyes had ...

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    3. Multimodal Imaging Analysis, SD-OCT and OCT Angiography, Retinal Variations Observed in Dialysis Patients

      Multimodal Imaging Analysis, SD-OCT and OCT Angiography, Retinal Variations Observed in Dialysis Patients

      Little knowledge exist on the short and long-term ophthalmological effect of the dialysis. Some studies stated a variation of the thickness subfoveal choroidal before and after a session of dialyse as well as variations of the coat of optical fibers measured in OCT. The Optical Coherence Tomography angiography OCT is a not invasive imaging technique which is now a part of examinations of investigation in imaging of retina. This technique allows to study the retinal macula vascularization without injection of contrast agent and thus allows to deepen the knowledge in medical domains where the exploration was to limited because of ...

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    4. Imaging probes and associated devices, systems, and methods utilizing an elastomeric optical element

      Imaging probes and associated devices, systems, and methods utilizing an elastomeric optical element

      The imaging probe can comprise a housing, having a proximal region configured to be coupled to an optical cable; a cannula, extending from a distal region of the housing; an optical guide, positioned partially in the housing and partially in the cannula, configured to receive an imaging light from the cable in the proximal region of the housing, and to guide the imaging light towards a distal end of the cannula; an optical focusing element, configured to receive the imaging light from the optical guide, and to emit a focused imaging light; an elastomeric optical element, configured to receive the ...

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    5. Specsavers Uses Topcon OCT In Its Stores

      Specsavers Uses Topcon OCT In Its Stores

      Topcon Healthcare Solutions, Inc., a wholly-owned subsidiary of Topcon America Corporation (“Topcon”) based in Oakland, NJ, has announced that eye health provider Specsavers had recently completed equipping its stores with Topcon's Optical Coherence Tomography (OCT) instruments. On September 21, 2018, Specsavers had reported that Specsavers Blacktown (NSW) had become the 200th store in Australia and New Zealand (ANZ) to have OCT technology. An OCT is often used for the early detection of sight-threatening diseases such as glaucoma, diabetic retinopathy and age-related macular degeneration (AMD). Topcon’s OCT technology is now a part of every eye exam. With this consistent ...

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    6. Optical Coherence Tomography Angiography Evolution of Choroidal Neovascular Membrane in Choroidal Rupture Managed by Intravitreal Bevacizumab

      Optical Coherence Tomography Angiography Evolution of Choroidal Neovascular Membrane in Choroidal Rupture Managed by Intravitreal Bevacizumab

      Purpose . To describe a case of a 25-year-old man with choroidal neovascularization (CNV) secondary to traumatic choroidal rupture treated with intravitreal bevacizumab and to evaluate the vascular structure of the area near the traumatic choroidal rupture. Methods . The patient underwent complete ophthalmologic evaluation, including best-corrected visual acuity (BCVA), intraocular pressure, anterior segment and funds examination, and optical coherence tomography angiography (OCTA) at baseline and on each follow-up visit. Fluorescein angiography (FA) was performed at baseline. Intravitreal bevacizumab was administered at the time of choroidal neovascular membrane diagnosis. Results . At baseline, ophthalmoscopic examination of the left eye revealed four subretinal macular ...

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    7. Non-Invasive Quantification of the Growth of Cancer Cell Colonies by a Portable Optical Coherence Tomography

      Non-Invasive Quantification of the Growth of Cancer Cell Colonies by a Portable Optical Coherence Tomography

      Investigation of tumor development is essential in cancer research. In the laboratory, living cell culture is a standard bio-technology for studying cellular response under tested conditions to predict in vivo cellular response. In particular, the colony formation assay has become a standard experiment for characterizing the tumor development in vitro. However, quantification of the growth of cell colonies under a microscope is difficult because they are suspended in a three-dimensional environment. Thus, optical coherence tomography (OCT) imaging was develop in this study to monitor the growth of cell colonies. Cancer cell line of Huh 7 was used and the cells ...

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    8. Macular colobomata: Comparison of clinical and optical coherence tomography features with serological result

      Macular colobomata: Comparison of clinical and optical coherence tomography features with serological result

      Purpose To assess the correlation between the morphological features and serology in eyes with macular colobomata (MC). Design Retrospective comparative case series Methods Setting: Institutional Study population Patients presenting with MC to the retina clinic over a period of two years (January 2016 to December 2017) Interventional/Observational procedure: Color fundus and swept source optical coherence tomography (SS-OCT, Topcon Inc.) features were reviewed and assessed in three groups based on the serum IgG results: positive for Toxoplasma, positive for Cytomegalovirus (CMV), and serology negative. Main outcome measure Morphological features on clinical and OCT-based examination Results A total of 49 eyes ...

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    9. Miniature all-fiber axicon probe with extended Bessel focus for optical coherence tomography

      Miniature all-fiber axicon probe with extended Bessel focus for optical coherence tomography

      The trade-off between lateral resolution and depth of focus (DOF) severely limits the capability of endoscopic optical coherence tomography (OCT) for high-resolution deep-tissue imaging. To address this issue, we developed a novel miniature all-fiber axicon OCT probe by inserting a segment of gradient-index (GRIN) fiber between a piece of single-mode fiber (SMF) and an axicon polished from a no-core fiber. The GRIN lens served as a beam expander extending the probe DOF by 5.2 times while maintaining a high lateral resolution of 2 μm. The DOF extension was experimentally verified by measuring the axial profile of the probe output ...

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      Mentions: Wei Wang
    10. Quantitative quality-control metrics for in vivo oximetry in small vessels by visible light optical coherence tomography angiography

      Quantitative quality-control metrics for in vivo oximetry in small vessels by visible light optical coherence tomography angiography

      Biological functions rely on local microvasculature to deliver oxygen and nutrients and carry away metabolic waste. Alterations to local oxygenation levels are manifested in diseases including cancer, diabetes mellitus, etc. The ability to quantify oxygen saturation (sO 2 ) within microvasculature in vivo to assess local tissue oxygenation and metabolic function is highly sought after. Visible light optical coherence tomography (vis-OCT) angiography has shown promise in reaching this goal. However, achieving reliable measurements in small vessels can be challenging due to the reduced contrast and requires data averaging to improve the spectral data quality. Therefore, a method for quality-control of the ...

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    11. Vascular and structural alterations of the choroid evaluated by optical coherence tomography angiography and optical coherence tomography after half-fluence photodynamic therapy in chronic central serous chorioretinopathy

      Vascular and structural alterations of the choroid evaluated by optical coherence tomography angiography and optical coherence tomography after half-fluence photodynamic therapy in chronic central serous chorioretinopathy

      Purpose To concurrently evaluate the effect of half-fluence photodynamic therapy (hf PDT) on choriocapillaris (CC) perfusion and choroidal structure in chronic central serous chorioretinopathy (CSC). Methods This prospective study included 48 eyes of 41 patients with chronic CSC. Enhanced depth imaging optical coherence tomography and optical coherence tomography angiography (OCTA) images were analyzed. Choroidal area (CA), luminal area (LA), and stromal area (SA) were computed using Image J software. Results One month after hf-PDT, total CA decreased to 1.312 mm 2 from 1.490 mm 2 ( p  < 0.001), LA decreased to 0.981 mm 2 from 1.097 ...

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    12. Comparison of retinal nerve fiber layer thickness between normal population and patients with diabetes mellitus using optical coherence tomography

      Comparison of retinal nerve fiber layer thickness between normal population and patients with diabetes mellitus using optical coherence tomography

      Objective: To compare the difference in peripapillary Retinal Nerve Fibre Layer (RNFL) thickness between normal population and Type-II diabetic patients without diabetic retinopathy using Spectral Domain Optical Coherence Tomography (SD OCT). Methods: This cross sectional study was carried out at PNS Shifa Naval Hospital, from May 2017 to November 2017. Out of 200 eyes, 100 eyes were of normal individuals and 100 eyes were of Type-II diabetic patients without diabetic retinopathy. Both groups were age and gender matched. Average RNFL thickness, along with RNFL of each quadrant of individuals was noted using SD OCT, and compared between two groups. Results ...

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    13. Impact of segmentation density on spectral domain optical coherence tomography assessment in Stargardt disease

      Impact of segmentation density on spectral domain optical coherence tomography assessment in Stargardt disease

      Purpose Automated spectral domain optical coherence tomography (SD-OCT) segmentation algorithms currently do not perform well in segmenting individual intraretinal layers in eyes with Stargardt disease (STGD). We compared selective B-scan segmentation strategies for generating mean retinal layer thickness and preserved area data from SD-OCT scans in patients with STGD1. Methods Forty-five eyes from 40 Stargardt patients were randomly selected from the ongoing Natural History of the Progression of Atrophy Secondary to Stargardt Disease (ProgStar) study. All eyes underwent SD-OCT using a standard macular volume consisting of 1024 × 49 equally spaced B-scans within a 20 × 20 degree field centered on the ...

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    14. Fundus autofluorescence and spectral domain optical coherence tomography as predictors for long-term functional outcome in rhegmatogenous retinal detachment

      Fundus autofluorescence and spectral domain optical coherence tomography as predictors for long-term functional outcome in rhegmatogenous retinal detachment

      Purpose To detect pre- and postoperative retinal changes in fundus autofluorescence (AF) and spectral domain optical coherence tomography (SD-OCT) and to correlate these with functional outcome in patients with primary rhegmatogenous retinal detachment (RRD). Methods A prospective, 30-month study of patients operated with 25-gauge vitrectomy for primary RRD. Patients were examined preoperatively and after 6 and 30 months, using ultrawide-field AF images (UWFI) (Optos 200Tx) and SD-OCT (Topcon 3D OCT-2000) imaging. Results Of 84 patients (84 eyes) included at baseline, 100.0 and 86.9% were re-examined at month 6 and 30, respectively. Preoperative findings such as macular attachment, detachment ...

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    15. Anterior segment optical coherence tomography and its clinical applications: a review

      Anterior segment optical coherence tomography and its clinical applications: a review

      Anterior segment optical coherence tomography (AS‐OCT) has become one of the cornerstones of non‐contact imaging modalities for assessing such structures as the cornea, anterior chamber angle, aqueous outflow pathway, sclera, and ocular surface structures. As such, it has a broad range of clinical applications, which have been independently reported in the literature. This paper aims to present a review of extant literature on the utility of AS‐OCT and its efficacy in clinical applications, and to evaluate the quality of available evidence. The following databases were searched from inception to 24 June 2018: Medline via Ovid, Cochrane Central ...

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    Topcon to Provide Free Cloud Storage on OCT Devices High-Quality Imaging Brings Vision to Researchers and Patients Dynamic Optical Coherence Tomography Is a New Technique for Imaging Skin Around Lower Extremity Wounds Measuring Barrett’s Epithelial Thickness with Volumetric Laser Endomicroscopy as a Biomarker to Guide Treatment Extended Coherence Length and Depth Ranging Using a Fourier-Domain Mode-Locked Frequency Comb and Circular Interferometric Ranging Santec Announce a Record Wavelength Scan for an Electrically Pumped VCSEL Acqiris launches the break-through SA2 signal acquisition platform starting with the SA220 14-bit, 2 GS/s ADC Card, designed for easy integration Thorlabs Extends VEGA Swept Source OCT Offering Summary of 6th International Meeting on OCT Angiography & Advances in OCT in Rome December 2018: A Tremendous Success Volumetric analysis of breast cancer tissues using machine learning and swept-source optical coherence tomography System Engineer / Senior System Engineer Opening at NinePoint Medical Postdoc Position at Vanderbilt University
  6. Recent Quotes

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      By Eric L. Buckland
    2. The VEGA series swept source OCT imaging systems have proven to be an excellent tool for a multitude of imaging applications. With this system series update, we aimed to increase the performance and ease of use for customers...The OCT applications team is available to assist with sample test runs and would be pleased to discuss how our OCT systems can be adapted to meet your needs.
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