1. Recent Articles From Around The Web

    1. Postdoctoral Fellow, In Vivo Ophthalmology at Roche in Basel, Switzerland

      Postdoctoral Fellow, In Vivo Ophthalmology at Roche in Basel, Switzerland

      We are seeking an exceptional, highly motivated, and talented postdoctoral fellow ( DVM , PhD, or MD-PhD) to perform in vivo and ex vivo experiments to explore safety of novel therapeutic targets for ocular diseases. In this position you will interact closely with other scientists and technicians in a laboratory. Specifically, you will: · Perform ocular examinations of animal models in drug safety studies; · Apply established in vivo imaging modalities, including optical coherence tomography ( OCT ) in conjunction with further diagnostic techniques such as electroretinography ( ERG ); · Participate in ongoing research projects ; · Train and supervise laboratory technicians and fellow researchers to expand skills and knowledge ...

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    2. RETINOCYTOMA WITH VITREOUS SEEDING: NEW INSIGHTS FROM ENHANCED DEPTH IMAGING OPTICAL COHERENCE TOMOGRAPHY AND HIGH-RESOLUTION POSTERIOR SEGMENT ULTRASONOGRAPHY

      RETINOCYTOMA WITH VITREOUS SEEDING: NEW INSIGHTS FROM ENHANCED DEPTH IMAGING OPTICAL COHERENCE TOMOGRAPHY AND HIGH-RESOLUTION POSTERIOR SEGMENT ULTRASONOGRAPHY

      Purpose: To report an atypical case of a patient with symptomatic retinocytoma associated with diffuse calcified vitreous seeds. Methods: Retrospective chart review. Results: A 46-year-old healthy woman presented with a history of floaters in the right eye for several months. She had been referred for abnormal findings in the retina and vitreous on routine examination. Visual acuity was 20/20. An incidental retinocytoma associated with extensive calcified vitreous seeding was observed. Enhanced depth optical coherence tomography showed an absence of normal retinal layers with numerous cystoid cavities throughout the lesion. High-resolution 20-MHz posterior B-scan ultrasonography demonstrated that the calcified vitreous ...

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    3. Optical Coherence Tomography Angiography In ADULT-ONSET Foveomacular Vitelliform Dystrophy

      Optical Coherence Tomography Angiography In ADULT-ONSET Foveomacular Vitelliform Dystrophy

      Purpose: To determine the ability of optical coherence tomography angiography (OCTA) to detect choroidal neovascularization (CNV) in the pseudohypopyon stage of adult-onset foveomacular vitelliform dystrophy. Methods: Prospective case series of eight consecutive patients with adult-onset foveomacular vitelliform dystrophy with at least one eye in the pseudohypopyon stage (a total of 14 eyes). Patients were assessed with spectral domain OCT, flourescein angiography, and OCTA. Main outcome measures were the presence or absence of CNV and any unifying patterns that could be identified on OCTA for adult-onset foveomacular vitelliform dystrophy. Results: One (12.5%) of eight eyes in the pseudohypopyon stage had ...

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    4. A Study Using Optical Coherence Tomography Angiography

      A Study Using Optical Coherence Tomography Angiography

      Purpose: To evaluate the prevalence, the vascular features, and the clinical diagnostic implication of retinal vascular abnormalities (RVAs) associated with neurofibromatosis Type 1 (NF1) in a large cohort of patients. Methods: Two hundred and ninety-four patients affected by NF1 were consecutively enrolled. The presence of RVAs was detected by means of infrared confocal scanning laser ophthalmoscopy images. Three hundred age- and race-matched healthy subjects were enrolled as a healthy control group. Fluorescein angiography, indocyanine green angiography, and optical coherence tomography angiography were also performed in patients with RVAs. Results: Retinal vascular abnormalities were detected in 18 patients with NF1 (6 ...

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    5. Spectral Domain Optical Coherence Tomography Versus Swept-Source Optical Coherence Tomography

      Spectral Domain Optical Coherence Tomography Versus Swept-Source Optical Coherence Tomography

      Purpose: To compare the visualization of the macula between spectral domain optical coherence tomography (SD-OCT) and swept-source OCT (SS-OCT) in gas-filled eyes. Methods: Sixty-one patients with common indications of gas tamponade, including 27 with macular holes and 34 with rhegmatogenous retinal detachment, who were treated with vitrectomy and gas tamponade were imaged using both SD-OCT (3D-OCT 2000, Topcon, Tokyo, Japan) and SS-OCT (DRI-OCT, Topcon) at 1, 3, and 7 days after the surgery. Good visualization of the macular area was defined as 1) visible foveal contour and discriminable status of hole (open or closed) for macular hole and 2) visible ...

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    6. Postdoctoral Fellow: Biophotonics Stanford University / Vanderbilt University

      Postdoctoral Fellow: Biophotonics Stanford University / Vanderbilt University

      The Stanford Biomedical Optics group (http://sbo.stanford.edu) develops optical imaging and sensing technologies for clinical and basic science applications, with additional interest in the development of low-cost and portable technologies for low-resource environments.

      We are looking to hire two new postdocs with core strengths and interest in biophotonics to join our lab as we make the exciting transition from Stanford to Vanderbilt University in Nashville, TN in Summer 2018. We especially encourage applicants with demonstrated expertise in instrumentation, signal processing and or computer programming for optical coherence tomography, advanced microscopy and/or point-of-care technology. Experience with small animal ...

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    7. 'Girl with Pearl Earring' to undergo examination

      'Girl with Pearl Earring' to undergo examination

      One of the world's most famous paintings "Girl with a Pearl Earring" is to undergo a two-week scientific examination in front of curious visitors to the Dutch museum where it lives. The luminescent tableau painted by Dutch master Johannes Vermeer around 1665 was last examined in 1994 during a conservation treatment at the Mauritshuis museum in the centre of The Hague. "Although further restoration is not yet required, major advances in non-invasive technical analysis have been made over the last 25 years," the museum said in a statement. Researchers have long been fascinated by the painting of a young ...

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    8. Artificial intelligence quickly and accurately diagnoses eye diseases and pneumonia

      Artificial intelligence quickly and accurately diagnoses eye diseases and pneumonia

      Using artificial intelligence and machine learning techniques, researchers at Shiley Eye Institute at UC San Diego Health and University of California San Diego School of Medicine, with colleagues in China, Germany and Texas, have developed a new computational tool to screen patients with common but blinding retinal diseases, potentially speeding diagnoses and treatment. The findings are published in the February 22 issue of Cell . "Artificial intelligence (AI) has huge potential to revolutionize disease diagnosis and management by doing analyses and classifications involving immense amounts of data that are difficult for human experts—and doing them rapidly," said senior author Kang ...

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    9. Design and implementation of a low-cost, portable OCT system

      Design and implementation of a low-cost, portable OCT system

      Optical coherence tomography (OCT) is a widely used biomedical imaging tool, primarily in ophthalmology to diagnose and stage retinal diseases. In order to increase access for a wider range of applications and in low resource settings, we developed a portable, low-cost OCT system that has comparable imaging performance to commercially available systems. Here, we present the system design and characterization and compare the system performance to other commercially available OCT systems. In addition, future cost reductions and potential additional applications of the low-cost OCT system are discussed.

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    10. Carotid artery stenting with optical coherence tomography

      Carotid artery stenting with optical coherence tomography

      A 61-year-old man underwent a left cervical internal carotid artery stenting following a recent ischemic stroke. Postoperative angiography was satisfactory and did not reveal any in-stent filling defect ( figure 1A ). Optical coherence tomography (OCT) probe was used to visualize the endoluminal area following stenting. OCT confirmed optimum placement of the stent and reveled a small plaque protrusion from the stent struts following deployment ( figure 1B ).

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    11. Artificial intelligence quickly and accurately diagnoses eye diseases and pneumonia

      Artificial intelligence quickly and accurately diagnoses eye diseases and pneumonia

      Using artificial intelligence and machine learning techniques, researchers at Shiley Eye Institute at UC San Diego Health and University of California San Diego School of Medicine, with colleagues in China, Germany and Texas, have developed a new computational tool to screen patients with common but blinding retinal diseases, potentially speeding diagnoses and treatment. The findings are published in the February 22 issue of Cell . "Artificial intelligence (AI) has huge potential to revolutionize disease diagnosis and management by doing analyses and classifications involving immense amounts of data that are difficult for human experts -- and doing them rapidly," said senior author Kang ...

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    12. First of its Kind: Peering into the Heart without Touching

      First of its Kind: Peering into the Heart without Touching

      More than 320 million people live in the United States. Staggeringly, most of them will die from some form of heart disease. As the leading cause of death in the U.S., heart disease also occupies the minds of great researchers, who continue to develop breakthroughs to advance treatments and science. That includes University of Houston professor of biomedical engineering Kirill Larin who has developed what he describes as a “frontier technology” that can immediately assess if heart medicine is working and scar tissue healing following a heart attack. No biopsies needed, no invasive measures taken. Larin simply peers into ...

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    13. Optical Coherence Tomography Examination of the Anterior Segment in a Case of Corneal Perforation and Lens Trauma by Chestnut Burr

      Optical Coherence Tomography Examination of the Anterior Segment in a Case of Corneal Perforation and Lens Trauma by Chestnut Burr

      Chestnut burrs, the thorny encapsulation of chestnut fruit, can sometimes cause corneal injuries and ulceration, with poor prognoses. We report a case of corneal perforation and damaged anterior lens capsule due to a chestnut burr, using anterior segment optical coherence tomography (AS-OCT). A 67-year-old woman with a chestnut burr injury in her right eye was referred to our hospital. Her right best-corrected visual acuity (BCVA) was 0.8. Slit-lamp examination and AS-OCT showed perforation involving the endothelial layer at the center of the cornea. The iris and anterior lens capsule were damaged. Cell infiltration was observed around the wound. Bacterial ...

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  3. People in the News

    1. (2 articles) Kang Zhang
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  5. Picture Gallery

    Research Fellow/ Research Associate at The University of Western Australia Postdoctoral Positions Open in Neural, Cognitive, and Rehabilitation Engineering at University of Houston. Optometry-facilitated teleophthalmology: an audit of the first year in Western Australia Summary of Information: Introducing ADQ14OCT – A 14-bit digitizer optimized for Swept-Source Optical Coherence Tomography PhotoniCare wins Startup Challenge with pitch for non-invasive ear inspection Large-volume, low-cost, high-precision FMCW tomography using stitched DFBs Open PhD Position at the Institute of Medical Technology at Hamburg University of Technology “Bringing on the light” in a complex clinical scenario: Optical coherence tomography–guided discontinuation of antiplatelet therapy in cancer patients with coronary artery disease (PROTECT-OCT registry) High-speed optical coherence tomography by circular interferometric ranging OCT Application Engineer: Wasatch Photonics - North Carolina Imaging the Whole Human Eye Post-Doctoral Fellowship on Image Processing (OCT and OCTA) at Oregon Health & Science University
  6. Recent Quotes

    1. We started with middle ear infections because of our personal experience with this disease as both parents and patients. Our novel application of optical coherence tomography revolutionizes the diagnosis, treatment and monitoring of the middle ear infections that affect 80% of children.
      By Ryan L. Shelton
    2. With the assistance of the next generation Pantheris system, we helped restore blood flow within the previously blocked segment of the artery and most importantly achieved a great outcome for the patient.
      By Arne G. Schwindt
    3. OCT is the ‘work horse’ of the biomedical photonics research field ...“Integrating the components in photonics chips will further increase both the technical and the clinical capabilities of OCT. Furthermore, PIC-based OCT will not only make the current applications cheaper but also broaden its application scope.
      By Ton G. van Leeuwen
    4. This agreement represents an important commercial milestone for Conavi. China has the second largest volume of cardiovascular interventional procedures in the world and is growing quickly as a result of extensive investments in healthcare infrastructure. We are delighted to have found a partner that shares our vision of bringing the potential benefits of advanced image guidance to a broad range of existing and emerging minimally invasive cardiovascuar procedures to patients in China.
      By Brian K. Courtney
    5. We are thrilled to be celebrating three years since we introduced our AngioVue OCT Angiography imaging technology at the AAO in 2014.
      By Jay Wei
    6. Optovue continues to lead innovation in Optical Coherence Tomography (OCT) imaging with the first non-contact technique of measuring the epithelial layer of the cornea...Our epi-mapping software has been the subject of more than 200 publications, underscoring its importance and value in the care of patients with corneal and ocular surface conditions. With epi-mapping, physicians are able to quantify epithelial thickness in patients in a manner that is suitable for daily clinical practice.
      By Jay Wei
    7. Combining en-face OCT with movement detection within blood vessels, we get OCT-A, and with it a new imaging era.
      By Eric H. Souied
    8. Obtaining the Category III CPT code for OCT of the skin is an important step towards our goal of obtaining reimbursement and coverage, and we welcome the new codes that can be used by clinicians to record their clinical use of VivoSight OCT in their practice.
      By Jon Holmes
    9. We showed that you can take effectively any OCT system out there and, with minimal changes, boost its resolution to the point where it can detect anatomical features smaller than the size of a typical cell.
      By Adam de la Zerda
    10. This honor highlights the commitment Avinger has to bring the most advanced technology to market for physicians dedicated to treating PAD and their patients who are affected by this disease...Pantheris radically changes the treatment of vascular disease and the Edison Award represents a win for our entire Lumivascular portfolio.
      By John B. Simpson