1. Featured Articles

    1. Spectroscopic optical coherence refraction tomography

      Explore OSA | OSA Publishing
      Spectroscopic optical coherence refraction tomography

      In optical coherence tomography (OCT), the axial resolution is often superior to the lateral resolution, which is sacrificed for long imaging depths. To address this anisotropy, we previously developed optical coherence refraction tomography (OCRT), which uses images from multiple angles to computationally reconstruct an image with isotropic resolution, given by the OCT axial resolution. On the other hand, spectroscopic OCT (SOCT), an extension of OCT, trades axial resolution for spectral resolution and hence often has superior lateral resolution. Here, we present spectroscopic OCRT (SOCRT), which uses SOCT images from multiple angles to reconstruct a spectroscopic image with isotropic spatial resolution ...

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      Mentions: Joseph A. Izatt Duke University Sina Farsiu

    2. NIR-II dual-modal optical coherence tomography and photoacoustic imaging-guided dose-control cancer chemotherapy

      Explore ACS Publications Home Page Gastroenterology
      NIR-II dual-modal optical coherence tomography and photoacoustic imaging-guided dose-control cancer chemotherapy

      In this study, an organic nano-drug delivery platform was constructed as a biocompatible cancer chemotherapeutic system, in which clini-cally approved sorafenib was loaded in the redox-responsive polymeric micelles, enabling dose-control release of drug to cancer tissues. In addition, visualizing tumor microenvironment changes is also essential for cancer chemotherapy, which can provide a priori and feedback control of drug delivery with reduced side effect. Therefore, second near-infrared window (NIR-II) dual-modal optical coherence tomogra-phy (OCT) and photoacoustic imaging were performed for real-time visualizing tumor microenvironment changes in vivo during chemo-therapy. In particular, the tumor angiogenesis, the vascular networks density change, and the ...

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    3. Open Rank Tenure Track Faculty Position in Retina Research, University of Rochester, Rochester, NY

      Explore Optical Coherence Tomography News Jobs & Studentships
      Open Rank Tenure Track Faculty Position in Retina Research, University of Rochester, Rochester, NY

      Open Rank Tenure Track Faculty Position in Retina Research, University of Rochester, Rochester, NY The University of Rochester Flaum Eye Institute has a tenure-track position available for scientists working in retina research with a desire to utilize high resolution retinal imaging. A strategic goal of the Flaum Eye Institute is to develop and apply innovative new capabilities to study the structure and function of the retina in healthy and diseased eyes. This includes basic research on a number of animal model systems including (but not limited to) mouse and non-human primate systems. Research may also involve human imaging and the ...

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      Mentions: University of Rochester Geunyoung Yoon

    4. NTU scientists develop handheld, high-resolution medical imaging device

      Explore EurekAlert! Probes
      NTU scientists develop handheld, high-resolution medical imaging device

      NTU scientists develop handheld, high-resolution medical imaging device with potential for bedside scanning Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed the prototype of a handheld medical imaging device that can produce images down to resolutions of 1 to 2 micrometres. This is detailed enough to spot the first signs of tumours in specific cells and is about 100 times higher resolution than what X-Ray, computed tomography (CT) and Magnetic Resonance Imaging (MRI) machines can provide. The technology behind the device is a result of six years of optical imaging research and was jointly developed by a team ...

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      Mentions: Imperial College London Harvard University Nanyang Technological University

    5. COMPARISON OF POST STENT OPTICAL COHERENCE TOMOGRAPHY FINDINGS AMONG THREE SUBTYPES OF CALCIFIED CULPRIT PLAQUES IN PATIENTS WITH ACUTE CORONARY SYNDROME

      Explore onlinejacc.org Cardiology
      COMPARISON OF POST STENT OPTICAL COHERENCE TOMOGRAPHY FINDINGS AMONG THREE SUBTYPES OF CALCIFIED CULPRIT PLAQUES IN PATIENTS WITH ACUTE CORONARY SYNDROME

      Background Recently, three subtypes of calcified plaques at the culprit lesion were reported in patients with acute coronary syndrome (ACS): eruptive calcified nodule, superficial calcific sheet, and calcified protrusion. Methods A total of 157 patients with ACS and calcified plaque at the culprit lesion were selected from our database. Optical coherence tomography (OCT) findings at index procedure and after stent implantation were compared among the three subgroups. Results In the final analysis, 92 cases were included. Pre-procedural OCT showed eruptive calcified nodules in 20 (21.7%) cases, superficial calcific sheets in 66 (71.7%), and calcified protrusion in 6 (6 ...

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      Mentions: Massachusetts General Hospital Ik-Kyung Jang Masamichi Takano

    6. Three‐dimensional mapping of the attenuation coefficient in optical coherence tomography to enhance breast tissue micro‐architecture contrast

      Explore Wiley Online Library Oncology
      Three‐dimensional mapping of the attenuation coefficient in optical coherence tomography to enhance breast tissue micro‐architecture contrast

      Effective intraoperative tumor margin assessment is needed to reduce re‐excision rates in breast‐conserving surgery (BCS). Mapping the attenuation coefficient in optical coherence tomography (OCT) throughout a sample to create an image (attenuation imaging) is one promising approach. For the first time, three‐dimensional OCT attenuation imaging of human breast tissue micro‐architecture using a wide‐field (up to ~45 × 45 × 3.5 mm) imaging system is demonstrated. Representative results from three mastectomy and one BCS specimen (from 31 specimens) are presented with co‐registered postoperative histology. Attenuation imaging is shown to provide substantially improved contrast over OCT, delineating ...

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      Mentions: University of Western Australia Brendan F. Kennedy

    7. Novel Tunable Lasers for Optical Coherence Tomography: Marie Curie Early Stage Positions to train towards PhD in an European Innovative Training Network

      Explore Optical Coherence Tomography News Jobs & Studentships
      Novel Tunable Lasers for Optical Coherence Tomography: Marie Curie Early Stage Positions to train towards PhD in an European Innovative Training Network

      We are recruiting for a PhD Studentship in the fields of Optics and Laser Physics, with emphasis on optical coherence tomography for a period of 36 months starting up to 31 January 2021, within the Applied Optics Group, School of Physical Sciences. These are supported by the Marie Curie Innovative Training Network scheme, 860807, EU funded, jointly organised with 14 other universities, companies and hospitals in Europe. You will spend time at the University of Kent and at the other beneficiaries or associated partners. Supervision will be provided in an European setting where specialized and complementary training will be provided ...

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      Mentions: Université Pierre et Marie Curie Adrian G. Podoleanu University of Kent

    9. ZEISS Medical Technology Announces Changes in Ophthalmic Devices Executive Leadership

      Explore Optical Coherence Tomography News Ophthalmology , Other Business News
      ZEISS Medical Technology Announces Changes in Ophthalmic Devices Executive Leadership

      Effective 1 May 2020, Jim Mazzo will retire from his position as President Ophthalmic Devices and Head of the Ophthalmic Devices Strategic Business Unit for ZEISS. He will continue to support ZEISS as an advisor. With over forty years in the ophthalmic industry, Jim has successfully transformed ZEISS Global Ophthalmic Devices as the number two industry leader in Ophthalmology by creating a strong customer focused organization within his three plus years with ZEISS. "I am very proud of what we have accomplished for customers and employees and pleased to hand over responsibility to Euan and the team. With this team ...

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      Mentions: University of London Carl Zeiss Meditec Ludwin Monz

    10. Optical Coherence Tomography Angiography of Idiopathic Foveal Hypoplasia and Its Correlation With Visual Acuity

      Explore LWW Online Ophthalmology
      Optical Coherence Tomography Angiography of Idiopathic Foveal Hypoplasia and Its Correlation With Visual Acuity

      SIGNIFICANCE Foveal hypoplasia is described clinically by the absence of a foveal pit and subsequent reduction in visual acuity. Optical coherence tomography angiography provides precise segmentation of the retinal vascular supply demonstrating the vascular perfusion in affected patients. Preservation of perfusion is linked to visual acuity and function. PURPOSE This case report describes a patient with foveal hypoplasia and preservation of visual acuity with preserved retinal capillary density of the superficial and deep capillary plexuses on optical coherence tomography angiography. In addition, the diagnostic findings of foveal hypoplasia as seen on optical coherence tomography angiography will be described. CASE REPORT ...

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    11. Optical coherence tomography/angiography-guided tumor ablation with a continuous-wave laser diode

      Explore IEEE Xplore
      Optical coherence tomography/angiography-guided tumor ablation with a continuous-wave laser diode

      Laser ablation can be an effective modality for treatment, but it is complicated to apply continuous-wave (CW) light sources for laser ablation because of the unpredictable photothermal damage. In this study, an integrated theranostic system combining a low-cost CW laser diode with optical coherence tomography (OCT)/angiography (OCTA) was utilized for the in vivo ablation of tumor tissues. To examine the effect of laser exposure on tissue scattering characteristics, the OCT backscattering intensities of non-ablated and ablated tissues were analyzed, and the effect on the skin microvasculature produced by laser ablation was quantitatively evaluated. Moreover, the integrated system and the ...

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      Mentions: National Taiwan University Meng-Tsan Tsai Chang Gung University

    12. Dual-band infrared optical coherence tomography using a single supercontinuum source

      Explore OSA | OSA Publishing NDE/NDT
      Dual-band infrared optical coherence tomography using a single supercontinuum source

      Recent developments and commercial availability of low-noise and bright infrared (IR) supercontinuum sources initiated intensive applied research in the last few years. Covering a significant part of near- and mid-infrared spectral ranges, supercontinuum radiation opened up unique possibilities and alternatives for the well-established imaging technique of optical coherence tomography (OCT). In this contribution, we demonstrate the development, performance, and maturity of a cost-efficient dual-band Fourier-domain IR OCT system (2 µm and 4 µm central wavelengths). The proposed OCT setup is elegantly employing a single supercontinuum source and a pyroelectric linear array. We discuss adapted application-oriented approaches to signal acquisition and ...

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      Mentions: Bettina Heise RECENDT

    13. Mirau-based line-field confocal optical coherence tomography

      Explore OSA | OSA Publishing
      Mirau-based line-field confocal optical coherence tomography

      Line-field confocal optical coherence tomography (LC-OCT) is an imaging technique in which A-scans are acquired in parallel through line illumination with a broadband laser and line detection with a line-scan camera. B-scan imaging at high spatial resolution is achieved by dynamic focusing in a Linnik interferometer. This paper presents an LC-OCT device based on a custom-designed Mirau interferometer that offers similar spatial resolution and detection sensitivity. The device has the advantage of being more compact and lighter. In vivo imaging of human skin with a resolution of 1.3 µm × 1.1 µm (lateral × axial) is demonstrated over a field ...

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      Mentions: Arnaud Dubois Damae Medical

    14. Dynamic contrast in scanning microscopic OCT

      Explore arxiv.org
      Dynamic contrast in scanning microscopic OCT

      While optical coherence tomography (OCT) provides a resolution down to 1 micrometer it has difficulties to visualize cellular structures due to a lack of scattering contrast. By evaluating signal fluctuations, a significant contrast enhancement was demonstrated using time-domain full-field OCT (FF-OCT), which makes cellular and subcellular structures visible. The putative cause of the dynamic OCT signal is ATP-dependent motion of cellular structures in a sub-micrometer range, which provides histology-like contrast. Here we demonstrate dynamic contrast with a scanning frequency-domain OCT (FD-OCT). Given the inherent sectional imaging geometry, scanning FD-OCT provides depth-resolved images across tissue layers, a perspective known from histopathology ...

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      Mentions: Columbia University Gereon Hüttmann University of Lübeck

    15. Long-term in vivo Monitoring of Gliotic Sheathing of Ultrathin Entropic Coated Brain Microprobes with Fiber-based Optical Coherence Tomography

      Explore bioRxiv.org Neurology
      Long-term in vivo Monitoring of Gliotic Sheathing of Ultrathin Entropic Coated Brain Microprobes with Fiber-based Optical Coherence Tomography

      Microfabricated neuroprosthetic devices have made possible important observations on neuron activity; however, long-term high-fidelity recording performance of these devices has yet to be realized. Tissue-device interactions appear to be a primary source of lost recording performance. The current state of the art for visualizing the tissue response surrounding brain implants in animals is Immunohistochemistry + Confocal Microscopy, which is mainly performed after sacrificing the animal. Monitoring the tissue response as it develops could reveal important features of the response which may inform improvements in electrode design. Optical Coherence Tomography (OCT), an imaging technique commonly used in ophthalmology, has already been adapted ...

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      Mentions: University of Washington

    16. Comparative study of deep learning models for optical coherence tomography angiography

      Explore OSA | OSA Publishing
      Comparative study of deep learning models for optical coherence tomography angiography

      Optical coherence tomography angiography (OCTA) is a promising imaging modality for microvasculature studies. Meanwhile, deep learning has achieved rapid development in image-to-image translation tasks. Some studies have proposed applying deep learning models to OCTA reconstruction and have obtained preliminary results. However, current studies are mostly limited to a few specific deep neural networks. In this paper, we conducted a comparative study to investigate OCTA reconstruction using deep learning models. Four representative network architectures including single-path models, U-shaped models, generative adversarial network (GAN)-based models and multi-path models were investigated on a dataset of OCTA images acquired from rat brains. Three ...

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      Mentions: University of Erlangen Gangjun Liu Peking University

    17. Optical coherence tomography imaging of plant root growth in soil

      Explore OSA | OSA Publishing NDE/NDT , Other Non-Medical
      Optical coherence tomography imaging of plant root growth in soil

      Complex interactions between roots and soil provide the nutrients and physical support required for robust plant growth. Yet, visualizing the root–soil interface is challenged by soil’s opaque scattering characteristics. Herein, we describe methods for using optical coherence tomography (OCT) to provide non-destructive 3D and cross-sectional root imaging not available with traditional bright-field microscopy. OCT is regularly used for bioimaging, especially in ophthalmology, where it can detect retinal abnormalities. Prior use of OCT in plant biology has focused on surface defects of above-ground tissues, predominantly in food crops. Our results show OCT is also viable for detailed, in situ ...

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    18. See all articles

  2. Recent Articles From Around The Web

    2. Imaging retinal structures at cellular-level resolution by visible-light optical coherence tomography

      Explore OSA | OSA Publishing Ophthalmology
      Imaging retinal structures at cellular-level resolution by visible-light optical coherence tomography

      In vivo high-resolution images are the most direct way to understand retinal function and diseases. Here we report the use of visible-light optical coherence tomography with volumetric registration and averaging to achieve cellular-level retinal structural imaging in a rat eye, covering the entire depth of the retina. Vitreous fibers, nerve fiber bundles, and vasculature were clearly revealed, as well as at least three laminar sublayers in the inner plexiform layer. We also successfully visualized ganglion cell somas in the ganglion cell layer, cells in the inner nuclear layer, and photoreceptors in the outer nuclear layer and ellipsoid zone. This technique ...

      Read Full Article
      Mentions: Oregon Health & Science University Yali Jia

    3. Radial Artery Spiral Dissection Confirmed by OCT Without Guidewire Shadow

      Explore Invasive Cardiology Cardiology
      Radial Artery Spiral Dissection Confirmed by OCT Without Guidewire Shadow

      A 75-year-old man underwent right transradial coronary angiography because of acute myocardial infarction. Postprocedural radial angiography revealed a dissection with a spiral luminal filling defect in the proximal radial artery corresponding to a National Heart, Lung, and Blood Institute type D dissection (Figure 1A; Video 1). In order to acquire a full, 360° optical coherence tomography (OCT) image, we withdrew the guidewire out of the sheath ahead of pullback and left the OCT imaging wire in the vessel alone. However, subsequent pullbacks were performed without any difficulties. Without the guidewire shadow, it was clear that the dissection started from a ...

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    4. Intraretinal Fluid Pattern Characterization in Optical Coherence Tomography Images

      Explore MDPI Open Access Journals Platform Ophthalmology
      Intraretinal Fluid Pattern Characterization in Optical Coherence Tomography Images

      Optical Coherence Tomography (OCT) has become a relevant image modality in the ophthalmological clinical practice, as it offers a detailed representation of the eye fundus. This medical imaging modality is currently one of the main means of identification and characterization of intraretinal cystoid regions, a crucial task in the diagnosis of exudative macular disease or macular edema, among the main causes of blindness in developed countries. This work presents an exhaustive analysis of intensity and texture-based descriptors for its identification and classification, using a complete set of 510 texture features, three state-of-the-art feature selection strategies, and seven representative classifier strategies ...

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    5. Procedural and one-year outcomes of patients treated with orbital and rotational atherectomy with mechanistic insights from optical coherence tomography

      Explore eurointervention.pcronline.com Cardiology
      Procedural and one-year outcomes of patients treated with orbital and rotational atherectomy with mechanistic insights from optical coherence tomography

      Aims: We sought to evaluate procedural complications and one-year clinical outcomes for patients who underwent percutaneous coronary intervention (PCI) with orbital (OA) and rotational atherectomy (RA). Methods and results: From a total of 13,467 patients who underwent PCI in our hospital between January 2013 and June 2016, 1,149 consecutive patients were treated with atherectomy for moderately-severely calcified lesions (184 with OA, 965 with RA). Procedural complications were similarly observed in the two groups except for higher dissection and perforation rates with OA. Major adverse cardiovascular events (MACE) were defined as the composite of death, myocardial infarction or target ...

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      Mentions: Mount Sinai School of Medicine

    6. Myocardial Infarction Complicating Vasospastic Angina in a Female Patient—Case Report

      Explore scirp.org Cardiology
      Myocardial Infarction Complicating Vasospastic Angina in a Female Patient—Case Report

      Coronary artery vasospasm is an infrequent cause of acute coronary syndrome (ACS). A 50-year-old female developed persistent chest discomfort related to anterior STEMI. After an unsuccessful thrombolysis attempt, due to delay concern, the patient was then sent to the catheterization laboratory for rescue PCI. The coronary angiogram revealed a TIMI 3 flow proximal LAD significant stenosis with spastic appearance of the coronary arteries which has improved after intracoronary nitrates administration. Optical Coherence Tomography (OCT) excluded coronary artery dissection and haematoma also revealed thrombus on moderate atherosclerotic plaque. The patient was then pain-free; she was managed medically and discharged after few ...

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    7. OCT-A characterisation of recurrent type 3 macular neovascularisation

      Explore BJO Online
      OCT-A characterisation of recurrent type 3 macular neovascularisation

      Purpose To investigate optical coherence tomography angiography (OCT-A) findings in recurrent type 3 macular neovascularisation (MNV). Methods In this retrospective cohort study, consecutive patients with type 3 MNV secondary to age-related macular degeneration underwent OCT-A at three different time points: baseline, after anti-vascular endothelial growth factor treatment with complete resolution of the exudative signs (ie, non-exudative stage) and at the recurrence of exudation (ie, recurrence stage). Demographics and clinical findings were analysed, including OCT-A features of type 3 MNV recurrence. Results Twelve eyes (12 patients, mean age 78±7 years) were included. Using OCT-A, at baseline all type 3 MNVs ...

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      Mentions: Centre Hospitalier Intercommunal de Créteil Giuseppe Querques Eric H. Souied

    8. Quantitative Coronary Angiography Can Predict Cardiac Allograft Vasculopathy in Pediatric Heart Transplant Recipients

      Explore ScienceDirect Cardiology
      Quantitative Coronary Angiography Can Predict Cardiac Allograft Vasculopathy in Pediatric Heart Transplant Recipients

      Purpose Cardiac allograft vasculopathy (CAV) is a leading cause of death and re-transplantation (tx). Intravascular ultrasound (IVUS) and optical coherence tomography (OCT) are increasingly used for earlier detection, but lengthen procedure time and cost, and are unsuitable in small children. Coronary angiography is routine in all age groups but may be subjectively interpreted. We hypothesized that serial analysis of quantitative coronary angiography (QCA) is possible in infants and children and may also predict disease progression. Methods Pediatric recipients between Feb 1999 - July 2012 were studied. QCA was performed in two projections of the same region of the right (RCA), left ...

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    9. “Virtual Biopsies” of Normal Skin and Thermal and Chemical Burn Wounds

      Explore LWW Online Dermatology
      “Virtual Biopsies” of Normal Skin and Thermal and Chemical Burn Wounds

      The search for noninvasive methods to image and measure the mechanical properties of skin has been a frequent subject of research for many years. Although suction testing, elastography, and other testing can be noninvasive, these tests fail to yield comparable results to destructive tests such as uniaxial tensile testing. Accordingly, researchers have developed a technique to combine optical coherence tomography with vibrational analysis ( vibrational optical coherence tomography ) to image and analyze the biomechanical properties of tissues noninvasively and nondestructively. The result of this analysis is a “ virtual biopsy ” of skin , along with a physical analysis of the major components of ...

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    10. Dynamic optical coherence elastography (Thesis)

      Explore UR Research Institutional Repository
      Dynamic optical coherence elastography (Thesis)

      Dynamic optical coherence elastography (OCE) is a functional imaging modality which leverages the propagation of mechanical waves in order to estimate the mechanical properties of tissues. It is very useful since it does not require (i) a priori knowledge of force/stress, (ii) mandatory direct contact between the mechanical loading source and the tissue under study, and (iii) large deformation of tissues. Therefore, dynamic OCE shows promise for non-contact, in situ, and in vivo mechanical characterization of tissues with applications in laboratory and clinical studies. To date, the impact of using transient/continuous temporal excitation produced by one/multiple loading ...

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      Mentions: University of Rochester

    11. The evaluation and correlation of subfoveal choroidal thickness and macular hole apical and basal diameters with enhanced depth imaging optical coherence tomography in patients with idiopathic macular hole

      Explore Eye Reports Ophthalmology
      The evaluation and correlation of subfoveal choroidal thickness and macular hole apical and basal diameters with enhanced depth imaging optical coherence tomography in patients with idiopathic macular hole

      Purpose: To investigate the evaluation and correlation between apical and basal hole diameters and subfoveal choroidal thickness (SCT) in patients with idiopathic macular hole (IMH), using enhanced depth imaging optical coherence tomography (OCT). Methods: This cross-sectional study included 30 eyes of 30 patients with IMH and 30 healthy controls eyes. The SCT of subjects were measured using enhanced depth imaging OCT and the results were compared. In the IMH group, the mean horizontal apical and basal diameters of IMH were calculated and the correlation between mean apical and basal diameters and SCT were investigated. All patients with IMH underwent vitreoretinal ...

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    12. In vivo imaging of human cornea with highspeed and high-resolution Fourier-domain full-field optical coherence tomography

      Explore arxiv.org Ophthalmology
      In vivo imaging of human cornea with highspeed and high-resolution Fourier-domain full-field optical coherence tomography

      : Corneal evaluation in ophthalmology necessitates cellular-resolution and fast imaging techniques allowing accurate diagnoses. Currently, the fastest volumetric imaging technique is Fourier-domain full-field optical coherence tomography (FD-FF-OCT) that uses a fast camera and a rapidly tunable laser source. Here, we demonstrate high-resolution, highspeed, non-contact corneal volumetric imaging in vivo with FD-FF-OCT that can acquire a single 3D volume with a voxel rate of 7.8 GHz. The spatial coherence of the laser source was suppressed to prevent it from focusing to a spot on the retina, and therefore, exceeding the maximum permissible exposure (MPE). Inherently volumetric nature of FD-FF-OCT data enabled ...

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      Mentions: Maciej Wojtkowski Egidijus Auksorius

    13. Accuracy of swept source optical coherence tomography and ultrasound biomicroscopy for evaluation of posterior lens capsule in traumatic cataract

      Explore American Journal of Ophthalmology Ophthalmology
      Accuracy of swept source optical coherence tomography and ultrasound biomicroscopy for evaluation of posterior lens capsule in traumatic cataract

      Purpose To assess the efficacy of swept source optical coherence tomography (SS-OCT) and ultrasound biomicroscopy (UBM) in detecting posterior capsule (PC) defect in patients with traumatic cataract. Design Observational case-series Methods Sixty-seven eyes from 67 patients, without age limitation and with traumatic cataract severe enough to prevent slit lamp evaluation of the PC, included in a simple sequence without randomization. Patients underwent both 50 MHz UBM and SS-OCT evaluation of the PC by different operators. Then, cataract surgery was performed using a single technique. Results Sixty-seven eyes from 67 patients including 60 men and 7 women were studied. The mean ...

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    15. RAG-FW: A hybrid convolutional framework for the automated extraction of retinal lesions and lesion-influenced grading of human retinal pathology

      Explore IEEE Xplore
      RAG-FW: A hybrid convolutional framework for the automated extraction of retinal lesions and lesion-influenced grading of human retinal pathology

      The identification of retinal lesions plays a vital role in accurately classifying and grading retinopathy. Many researchers have presented studies on optical coherence tomography (OCT) based retinal image analysis over the past. However, to the best of our knowledge, there is no framework yet available that can extract retinal lesions from multi-vendor OCT scans and utilize them for the intuitive severity grading of the human retina. To cater this lack, we propose a deep retinal analysis and grading framework (RAG-FW). RAG-FW is a hybrid convolutional framework that extracts multiple retinal lesions from OCT scans and utilizes them for lesion-influenced grading ...

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      16. See all articles
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    1. (2 articles) Medical University of Vienna
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    3. (2 articles) University of Rochester
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  9. Picture Gallery

    Spectroscopic optical coherence refraction tomography NIR-II dual-modal optical coherence tomography and photoacoustic imaging-guided dose-control cancer chemotherapy Open Rank Tenure Track Faculty Position in Retina Research, University of Rochester, Rochester, NY NTU scientists develop handheld, high-resolution medical imaging device COMPARISON OF POST STENT OPTICAL COHERENCE TOMOGRAPHY FINDINGS AMONG THREE SUBTYPES OF CALCIFIED CULPRIT PLAQUES IN PATIENTS WITH ACUTE CORONARY SYNDROME Three‐dimensional mapping of the attenuation coefficient in optical coherence tomography to enhance breast tissue micro‐architecture contrast Novel Tunable Lasers for Optical Coherence Tomography: Marie Curie Early Stage Positions to train towards PhD in an European Innovative Training Network PhotoniCare Announces Nishant Mohan as their New Chief Technology and Product Officer ZEISS Medical Technology Announces Changes in Ophthalmic Devices Executive Leadership Optical Coherence Tomography Angiography of Idiopathic Foveal Hypoplasia and Its Correlation With Visual Acuity Optical coherence tomography/angiography-guided tumor ablation with a continuous-wave laser diode Dual-band infrared optical coherence tomography using a single supercontinuum source

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    1. In ophthalmology we have a wealth of eye images—fundus photographs, optical coherence tomography (OCT), etc.—that are fundamental to the diagnosis, monitoring, and treatment of a number of eye diseases, so this field is ideally suited for deep learning applications.
      By Felipe A. Medeiros
    2. We are delighted to have received MHLW approval of the Novasight Hybrid system. Clinical data in the past several years has increasingly demonstrated that intravascular imaging with either IVUS or OCT has significant potential to improve outcomes in the large number of patients being treated with angioplasty and stenting for coronary artery disease. However, there are substantial differences between the images generated by these two technologies. Until now, physicians in Japan have had to choose between IVUS or OCT when performing percutaneous coronary interventions (PCI). We are delighted that Conavi and Japan Lifeline can now begin to offer both of these highly complementary imaging techniques on a single catheter to physicians in Japan.
      By Brian K. Courtney
    3. It is such a huge honor to be recognized with this prestigious industry award for best healthcare product in 2020, and we’d like to thank SPIE and Photonics Media for sponsoring this incredible opportunity...Our team is working hard to provide better options to millions of patients who suffer from middle ear infections. Following our recent 510(k) clearance from the FDA, we cannot wait to see how the TOMi Scope impacts the standard of care for this incredibly common disease.
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    4. We developed an algorithm that can be used to automatically analyze optical coherence tomography (OCT) images of the retina to predict whether a patient is likely to respond to anti-VEGF treatments...This research represents a step toward precision medicine, in which such predictions help clinicians better select first-line therapies for patients based on specific disease conditions.
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    5. This milestone marks the first step towards establishing physician and patient reimbursement for our home OCT pipeline technology...We applaud the AMA’s CPT Editorial panel for establishing codes for billing remote diagnostic services and patient home monitoring services. We believe that a home-based OCT will be the future of monitoring patients with wet AMD, one that allows doctors to individualize their patients’ treatment.
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    6. We hope that this new lab between SNEC-SERI and NTU will be the start of an important programme to utilise engineering solutions to help and improve care of our patients with eye problems.
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    7. “At PhotoniCare we set out to solve the massive problem of frequent misdiagnosis of middle ear infections, and the overuse of antibiotics and referrals to surgery in children that result...We thank the FDA for clearing our TOMi Scope under a new product code unique to our technology, and look forward to bringing this innovation to doctors and patients very soon.”
      By Ryan L. Shelton
    8. The move to the new office space on Fox Drive has been exciting, to say the least...Part of the move includes a build out of a portion of the office space. So the #EnginEarGuys got to try our hand at interior design! Much of the design, however, was spearheaded by one of PhotoniCare’s engineers, Heather Howard. She helped the team navigate the moving process and make decisions on everything from our new manufacturing layout to the aesthetics – carpet, paint, and furniture!
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    9. “Our group has spent quite a few years working on developing the underlying imaging technology...This grant will support our translational efforts and allow us to identify ophthalmic surgeries that will directly benefit from real-time guidance and to better understand how surgical maneuvers impact postoperative visual function.
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    10. An historic issue with OCT is that the depth resolution is typically several times better than the lateral resolution...If the layers of imaged tissues happen to be horizontal, then they're well defined in the scan. But to extend the full power of OCT for live imaging of tissues throughout the body, a method for overcoming the tradeoff between lateral resolution and depth of imaging was needed.
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