1. Featured Articles

    1. An open-source robotic platform that enables automated monitoring of replicate biofilm cultivations using optical coherence tomography

      Explore Nature Publishing Group NDE/NDT , Other Non-Medical
      An open-source robotic platform that enables automated monitoring of replicate biofilm cultivations using optical coherence tomography

      The paper introduces a fully automated cultivation and monitoring tool to study biofilm development in replicate experiments operated in parallel. To gain a fundamental understanding of the relation between cultivation conditions and biofilm characteristics (e.g., structural, mechanical) a monitoring setup allowing for the standardization of methods is required. Optical coherence tomography (OCT) is an imaging modality ideal for biofilms since it allows for the monitoring of structure in real time. By integrating an OCT device into the open-source robotic platform EvoBot, a fully automated monitoring platform for investigating biofilm development in several flow cells at once was realized. Different ...

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      Mentions: University of Copenhagen

    2. Spectroscopic optical coherence refraction tomography

      Explore OSA | OSA Publishing
      Spectroscopic optical coherence refraction tomography

      In optical coherence tomography (OCT), the axial resolution is often superior to the lateral resolution, which is sacrificed for long imaging depths. To address this anisotropy, we previously developed optical coherence refraction tomography (OCRT), which uses images from multiple angles to computationally reconstruct an image with isotropic resolution, given by the OCT axial resolution. On the other hand, spectroscopic OCT (SOCT), an extension of OCT, trades axial resolution for spectral resolution and hence often has superior lateral resolution. Here, we present spectroscopic OCRT (SOCRT), which uses SOCT images from multiple angles to reconstruct a spectroscopic image with isotropic spatial resolution ...

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      Mentions: Joseph A. Izatt Duke University Sina Farsiu

    3. NIR-II dual-modal optical coherence tomography and photoacoustic imaging-guided dose-control cancer chemotherapy

      Explore ACS Publications Home Page Gastroenterology
      NIR-II dual-modal optical coherence tomography and photoacoustic imaging-guided dose-control cancer chemotherapy

      In this study, an organic nano-drug delivery platform was constructed as a biocompatible cancer chemotherapeutic system, in which clini-cally approved sorafenib was loaded in the redox-responsive polymeric micelles, enabling dose-control release of drug to cancer tissues. In addition, visualizing tumor microenvironment changes is also essential for cancer chemotherapy, which can provide a priori and feedback control of drug delivery with reduced side effect. Therefore, second near-infrared window (NIR-II) dual-modal optical coherence tomogra-phy (OCT) and photoacoustic imaging were performed for real-time visualizing tumor microenvironment changes in vivo during chemo-therapy. In particular, the tumor angiogenesis, the vascular networks density change, and the ...

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    4. Open Rank Tenure Track Faculty Position in Retina Research, University of Rochester, Rochester, NY

      Explore Optical Coherence Tomography News Jobs & Studentships
      Open Rank Tenure Track Faculty Position in Retina Research, University of Rochester, Rochester, NY

      Open Rank Tenure Track Faculty Position in Retina Research, University of Rochester, Rochester, NY The University of Rochester Flaum Eye Institute has a tenure-track position available for scientists working in retina research with a desire to utilize high resolution retinal imaging. A strategic goal of the Flaum Eye Institute is to develop and apply innovative new capabilities to study the structure and function of the retina in healthy and diseased eyes. This includes basic research on a number of animal model systems including (but not limited to) mouse and non-human primate systems. Research may also involve human imaging and the ...

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      Mentions: University of Rochester Geunyoung Yoon

    5. NTU scientists develop handheld, high-resolution medical imaging device

      Explore EurekAlert! Probes
      NTU scientists develop handheld, high-resolution medical imaging device

      NTU scientists develop handheld, high-resolution medical imaging device with potential for bedside scanning Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed the prototype of a handheld medical imaging device that can produce images down to resolutions of 1 to 2 micrometres. This is detailed enough to spot the first signs of tumours in specific cells and is about 100 times higher resolution than what X-Ray, computed tomography (CT) and Magnetic Resonance Imaging (MRI) machines can provide. The technology behind the device is a result of six years of optical imaging research and was jointly developed by a team ...

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      Mentions: Imperial College London Harvard University Nanyang Technological University

    6. COMPARISON OF POST STENT OPTICAL COHERENCE TOMOGRAPHY FINDINGS AMONG THREE SUBTYPES OF CALCIFIED CULPRIT PLAQUES IN PATIENTS WITH ACUTE CORONARY SYNDROME

      Explore onlinejacc.org Cardiology
      COMPARISON OF POST STENT OPTICAL COHERENCE TOMOGRAPHY FINDINGS AMONG THREE SUBTYPES OF CALCIFIED CULPRIT PLAQUES IN PATIENTS WITH ACUTE CORONARY SYNDROME

      Background Recently, three subtypes of calcified plaques at the culprit lesion were reported in patients with acute coronary syndrome (ACS): eruptive calcified nodule, superficial calcific sheet, and calcified protrusion. Methods A total of 157 patients with ACS and calcified plaque at the culprit lesion were selected from our database. Optical coherence tomography (OCT) findings at index procedure and after stent implantation were compared among the three subgroups. Results In the final analysis, 92 cases were included. Pre-procedural OCT showed eruptive calcified nodules in 20 (21.7%) cases, superficial calcific sheets in 66 (71.7%), and calcified protrusion in 6 (6 ...

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      Mentions: Massachusetts General Hospital Ik-Kyung Jang Masamichi Takano

    7. Three‐dimensional mapping of the attenuation coefficient in optical coherence tomography to enhance breast tissue micro‐architecture contrast

      Explore Wiley Online Library Oncology
      Three‐dimensional mapping of the attenuation coefficient in optical coherence tomography to enhance breast tissue micro‐architecture contrast

      Effective intraoperative tumor margin assessment is needed to reduce re‐excision rates in breast‐conserving surgery (BCS). Mapping the attenuation coefficient in optical coherence tomography (OCT) throughout a sample to create an image (attenuation imaging) is one promising approach. For the first time, three‐dimensional OCT attenuation imaging of human breast tissue micro‐architecture using a wide‐field (up to ~45 × 45 × 3.5 mm) imaging system is demonstrated. Representative results from three mastectomy and one BCS specimen (from 31 specimens) are presented with co‐registered postoperative histology. Attenuation imaging is shown to provide substantially improved contrast over OCT, delineating ...

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      Mentions: University of Western Australia Brendan F. Kennedy

    8. Novel Tunable Lasers for Optical Coherence Tomography: Marie Curie Early Stage Positions to train towards PhD in an European Innovative Training Network

      Explore Optical Coherence Tomography News Jobs & Studentships
      Novel Tunable Lasers for Optical Coherence Tomography: Marie Curie Early Stage Positions to train towards PhD in an European Innovative Training Network

      We are recruiting for a PhD Studentship in the fields of Optics and Laser Physics, with emphasis on optical coherence tomography for a period of 36 months starting up to 31 January 2021, within the Applied Optics Group, School of Physical Sciences. These are supported by the Marie Curie Innovative Training Network scheme, 860807, EU funded, jointly organised with 14 other universities, companies and hospitals in Europe. You will spend time at the University of Kent and at the other beneficiaries or associated partners. Supervision will be provided in an European setting where specialized and complementary training will be provided ...

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      Mentions: Université Pierre et Marie Curie Adrian G. Podoleanu University of Kent

    10. ZEISS Medical Technology Announces Changes in Ophthalmic Devices Executive Leadership

      Explore Optical Coherence Tomography News Ophthalmology , Other Business News
      ZEISS Medical Technology Announces Changes in Ophthalmic Devices Executive Leadership

      Effective 1 May 2020, Jim Mazzo will retire from his position as President Ophthalmic Devices and Head of the Ophthalmic Devices Strategic Business Unit for ZEISS. He will continue to support ZEISS as an advisor. With over forty years in the ophthalmic industry, Jim has successfully transformed ZEISS Global Ophthalmic Devices as the number two industry leader in Ophthalmology by creating a strong customer focused organization within his three plus years with ZEISS. "I am very proud of what we have accomplished for customers and employees and pleased to hand over responsibility to Euan and the team. With this team ...

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      Mentions: University of London Carl Zeiss Meditec Ludwin Monz

    11. Optical Coherence Tomography Angiography of Idiopathic Foveal Hypoplasia and Its Correlation With Visual Acuity

      Explore LWW Online Ophthalmology
      Optical Coherence Tomography Angiography of Idiopathic Foveal Hypoplasia and Its Correlation With Visual Acuity

      SIGNIFICANCE Foveal hypoplasia is described clinically by the absence of a foveal pit and subsequent reduction in visual acuity. Optical coherence tomography angiography provides precise segmentation of the retinal vascular supply demonstrating the vascular perfusion in affected patients. Preservation of perfusion is linked to visual acuity and function. PURPOSE This case report describes a patient with foveal hypoplasia and preservation of visual acuity with preserved retinal capillary density of the superficial and deep capillary plexuses on optical coherence tomography angiography. In addition, the diagnostic findings of foveal hypoplasia as seen on optical coherence tomography angiography will be described. CASE REPORT ...

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    12. Optical coherence tomography/angiography-guided tumor ablation with a continuous-wave laser diode

      Explore IEEE Xplore
      Optical coherence tomography/angiography-guided tumor ablation with a continuous-wave laser diode

      Laser ablation can be an effective modality for treatment, but it is complicated to apply continuous-wave (CW) light sources for laser ablation because of the unpredictable photothermal damage. In this study, an integrated theranostic system combining a low-cost CW laser diode with optical coherence tomography (OCT)/angiography (OCTA) was utilized for the in vivo ablation of tumor tissues. To examine the effect of laser exposure on tissue scattering characteristics, the OCT backscattering intensities of non-ablated and ablated tissues were analyzed, and the effect on the skin microvasculature produced by laser ablation was quantitatively evaluated. Moreover, the integrated system and the ...

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      Mentions: National Taiwan University Meng-Tsan Tsai Chang Gung University

    13. Dual-band infrared optical coherence tomography using a single supercontinuum source

      Explore OSA | OSA Publishing NDE/NDT
      Dual-band infrared optical coherence tomography using a single supercontinuum source

      Recent developments and commercial availability of low-noise and bright infrared (IR) supercontinuum sources initiated intensive applied research in the last few years. Covering a significant part of near- and mid-infrared spectral ranges, supercontinuum radiation opened up unique possibilities and alternatives for the well-established imaging technique of optical coherence tomography (OCT). In this contribution, we demonstrate the development, performance, and maturity of a cost-efficient dual-band Fourier-domain IR OCT system (2 µm and 4 µm central wavelengths). The proposed OCT setup is elegantly employing a single supercontinuum source and a pyroelectric linear array. We discuss adapted application-oriented approaches to signal acquisition and ...

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      Mentions: Bettina Heise RECENDT

    14. Mirau-based line-field confocal optical coherence tomography

      Explore OSA | OSA Publishing
      Mirau-based line-field confocal optical coherence tomography

      Line-field confocal optical coherence tomography (LC-OCT) is an imaging technique in which A-scans are acquired in parallel through line illumination with a broadband laser and line detection with a line-scan camera. B-scan imaging at high spatial resolution is achieved by dynamic focusing in a Linnik interferometer. This paper presents an LC-OCT device based on a custom-designed Mirau interferometer that offers similar spatial resolution and detection sensitivity. The device has the advantage of being more compact and lighter. In vivo imaging of human skin with a resolution of 1.3 µm × 1.1 µm (lateral × axial) is demonstrated over a field ...

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      Mentions: Arnaud Dubois Damae Medical

    15. Dynamic contrast in scanning microscopic OCT

      Explore arxiv.org
      Dynamic contrast in scanning microscopic OCT

      While optical coherence tomography (OCT) provides a resolution down to 1 micrometer it has difficulties to visualize cellular structures due to a lack of scattering contrast. By evaluating signal fluctuations, a significant contrast enhancement was demonstrated using time-domain full-field OCT (FF-OCT), which makes cellular and subcellular structures visible. The putative cause of the dynamic OCT signal is ATP-dependent motion of cellular structures in a sub-micrometer range, which provides histology-like contrast. Here we demonstrate dynamic contrast with a scanning frequency-domain OCT (FD-OCT). Given the inherent sectional imaging geometry, scanning FD-OCT provides depth-resolved images across tissue layers, a perspective known from histopathology ...

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      Mentions: Columbia University Gereon Hüttmann University of Lübeck

    16. Long-term in vivo Monitoring of Gliotic Sheathing of Ultrathin Entropic Coated Brain Microprobes with Fiber-based Optical Coherence Tomography

      Explore bioRxiv.org Neurology
      Long-term in vivo Monitoring of Gliotic Sheathing of Ultrathin Entropic Coated Brain Microprobes with Fiber-based Optical Coherence Tomography

      Microfabricated neuroprosthetic devices have made possible important observations on neuron activity; however, long-term high-fidelity recording performance of these devices has yet to be realized. Tissue-device interactions appear to be a primary source of lost recording performance. The current state of the art for visualizing the tissue response surrounding brain implants in animals is Immunohistochemistry + Confocal Microscopy, which is mainly performed after sacrificing the animal. Monitoring the tissue response as it develops could reveal important features of the response which may inform improvements in electrode design. Optical Coherence Tomography (OCT), an imaging technique commonly used in ophthalmology, has already been adapted ...

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      Mentions: University of Washington

    17. Comparative study of deep learning models for optical coherence tomography angiography

      Explore OSA | OSA Publishing
      Comparative study of deep learning models for optical coherence tomography angiography

      Optical coherence tomography angiography (OCTA) is a promising imaging modality for microvasculature studies. Meanwhile, deep learning has achieved rapid development in image-to-image translation tasks. Some studies have proposed applying deep learning models to OCTA reconstruction and have obtained preliminary results. However, current studies are mostly limited to a few specific deep neural networks. In this paper, we conducted a comparative study to investigate OCTA reconstruction using deep learning models. Four representative network architectures including single-path models, U-shaped models, generative adversarial network (GAN)-based models and multi-path models were investigated on a dataset of OCTA images acquired from rat brains. Three ...

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      Mentions: University of Erlangen Gangjun Liu Peking University

    18. Optical coherence tomography imaging of plant root growth in soil

      Explore OSA | OSA Publishing NDE/NDT , Other Non-Medical
      Optical coherence tomography imaging of plant root growth in soil

      Complex interactions between roots and soil provide the nutrients and physical support required for robust plant growth. Yet, visualizing the root–soil interface is challenged by soil’s opaque scattering characteristics. Herein, we describe methods for using optical coherence tomography (OCT) to provide non-destructive 3D and cross-sectional root imaging not available with traditional bright-field microscopy. OCT is regularly used for bioimaging, especially in ophthalmology, where it can detect retinal abnormalities. Prior use of OCT in plant biology has focused on surface defects of above-ground tissues, predominantly in food crops. Our results show OCT is also viable for detailed, in situ ...

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    19. See all articles

  2. Recent Articles From Around The Web

    1. Factors Affecting Repeatability of Foveal Avascular Zone Measurement Using Optical Coherence Tomography Angiography in Pathologic Eyes

      Explore Medical Journals Publisher Ophthalmology
      Factors Affecting Repeatability of Foveal Avascular Zone Measurement Using Optical Coherence Tomography Angiography in Pathologic Eyes

      Purpose: To determine factors that may affect the repeatability of the foveal avascular zone (FAZ) measurement obtained using optical coherence tomography angiography (OCTA) including instrument type, image segmentation, image quality, and fundus pathology. Patients and Methods: This prospective single-center study enrolled 43 subjects (85 eyes) with retinal vasculopathy, macular edema, optic pathology or normal contralateral eye. The macula was imaged twice using Optovue Angiovue and once using Cirrus Angioplex to obtain 3x3mm OCTA images centered on the fovea. Images were generated by the same operator within 30 mins. The FAZ size for the entire retinal thickness (“overall FAZ”) was measured ...

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      Mentions: Optovue Carl Zeiss Meditec UC Davis

    2. Macular choroidal thickness in patients with pseudoxanthoma elasticum measured by enhanced-depth imaging spectral-domain optical coherence tomography

      Explore Home - Springer Ophthalmology
      Macular choroidal thickness in patients with pseudoxanthoma elasticum measured by enhanced-depth imaging spectral-domain optical coherence tomography

      Background/objectives To analyze macular choroidal thickness in patients with pseudoxanthoma elasticum (PXE) by enhanced depth imaging optical coherence tomography (EDI-OCT). Subjects/methods This is a prospective cross-sectional study. Sixty-eight eyes of 34 patients with PXE and 68 normal eyes of 34 controls were included to study the macular area with enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT). Eyes with PXE were classified in three groups: those without choroidal neovascularization (CNV) or chorioretinal macular atrophy macular (Group 1); those with active CNV (Group 2) and those with macular atrophy secondary to inactive CNV (Group 3). Results Mean subfoveal choroidal ...

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    3. The use of anterior segment optical coherence tomography in evaluation of punctal stenosisL’utilisation de l’OCT-SA dans la sténose du point lacrymal

      Explore ScienceDirect Ophthalmology
      The use of anterior segment optical coherence tomography in evaluation of punctal stenosisL’utilisation de l’OCT-SA dans la sténose du point lacrymal

      Purpose To evaluate the applicability of anterior segment optical coherence tomography (AS-OCT) for objective diagnosis of punctal stenosis. Methods We report the use of AS-OCT in 3 cases of epiphora related to punctal stenosis. We followed the methodology described in previous studies. The examination was performed by a single technician using a single Spectralis OCT with the AS-OCT module. Three patients with complaints of epiphora (mean age = 80 years) were examined. The external punctal diameter was measured on both infrared (IR) and OCT images. The internal diameter was measured on OCT images at a depth of 500 μm. The diagnosis ...

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      Mentions: Heidelberg Spectralis

    4. Using optical coherence tomography angiography in assessment of the anti-vascular endothelial growth factor effect for pathological vascular tissue in age-related macular degeneration and polypoidal choroidal vasculopathy

      Explore SAGE Journals Ophthalmology
      Using optical coherence tomography angiography in assessment of the anti-vascular endothelial growth factor effect for pathological vascular tissue in age-related macular degeneration and polypoidal choroidal vasculopathy

      Purpose: Using optical coherence tomography angiography to assess and compare changes in pathological vascular tissue, including choroidal neovascularization in neovascular age-related macular degeneration and polypoidal complex in polypoidal choroidal vasculopathy, after treatment with anti-vascular endothelial growth factor. Methods: This is a retrospective observational case series study. Clinical data were collected, including that on the best-corrected visual acuity and images of spectrum domain optical coherence tomography and optical coherence tomography angiography of consecutive patients with macula-involved lesions, active pathological vascular tissue in neovascular age-related macular degeneration, and polypoidal complex in polypoidal choroidal vasculopathy who were treated with anti-vascular endothelial growth factor ...

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    5. Quantum-inspired detection for Spectral Domain Optical Coherence Tomography

      Explore arxiv.org
      Quantum-inspired detection for Spectral Domain Optical Coherence Tomography

      The intensity levels allowed by safety standards (ANSI or ICNIRP) limit the amount of light that can be used in a clinical setting to image highly scattering or absorptive tissues with Optical Coherence Tomography (OCT). To achieve high-sensitivity imaging at low intensity levels, we adapt a detection scheme - which is used in quantum optics for providing information about spectral correlations of photons - into a standard spectral domain OCT system. This detection scheme is based on the concept of Dispersive FourierTransformation, where a fibre introduces a wavelength-dependent time delay measured by a single-pixel detector, usually a high-speed photoreceiver. Here, we use ...

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      Mentions: Nicolaus Copernicus University University of Auckland Frederique Vanholsbeeck

    6. En face slab optical coherence tomography imaging successfully monitors progressive degenerative changes in the innermost layer of the diabetic retina

      Explore BMJ Open Diabetes Research & Care
      En face slab optical coherence tomography imaging successfully monitors progressive degenerative changes in the innermost layer of the diabetic retina

      Objective To evaluate the usefulness of en face slab optical coherence tomography (OCT) imaging for monitoring diabetic retinal neurodegeneration with supporting animal experimental data. Research design and methods We retrospectively examined 72 diabetic eyes over 3 years using Cirrus-HD OCT. Two-dimensional en face slab OCT images of the innermost retina were reconstructed and graded according to the ratio of dark area to total area, and relative red, green, and blue color area ratios were calculated and used as indexes for each en face slab OCT image. Values from en face OCT images were used for statistical analyses. To obtain insight ...

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      Mentions: Makoto Nakamura Kobe University Graduate School of Medicine

    7. Repeatability of Manual Measurement of Foveal Avascular Zone Area in Optical Coherence Tomography Angiography Images in High Myopia

      Explore KoreaMed Synapse Ophthalmology
      Repeatability of Manual Measurement of Foveal Avascular Zone Area in Optical Coherence Tomography Angiography Images in High Myopia

      Purpose To analyze the repeatability of manual measurement of foveal avascular zone (FAZ) area in an optical coherence tomography angiography (OCTA) image in high myopia. Methods This study comprised patients with high myopia and controls. Two consecutive FAZ areas of the superficial and deep capillary plexus were obtained using OCTA. The intraclass correlation coefficient (ICC) and coefficient of variation (CV) were assessed, and univariate and multivariate generalized linear mixed models were conducted to identify factors related to repeatability. Results Thirty eyes with high myopia and 34 eyes of healthy subjects were included in the study. The mean age in high ...

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      Mentions: Konyang University

    8. Fluorescein angiography versus optical coherence tomography angiography: FA vs OCTA Italian Study

      Explore SAGE Journals Ophthalmology
      Fluorescein angiography versus optical coherence tomography angiography: FA vs OCTA Italian Study

      Purpose: To assess the current role of fluorescein angiography after the introduction of optical coherence tomography angiography in real-life clinical practice. Methods: This was a multicentric retrospective observational study to evaluate the number of fluorescein angiography and optical coherence tomography angiography procedures performed by different devices from January 2013 to December 2018. The centers involved were Centro Italiano Macula (Rome), and ophthalmology departments of University “G. D’Annunzio” Chieti–Pescara (Chieti) and “Azienda Ospedaliero Universitaria Careggi” (Florence). Results: Out of 19,898 total fluorescein angiography procedures performed in the observation period, 3444 (17.3%) were in 2013, 3972 (19.9 ...

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      Mentions: Maria Cristina Savastano Bruno Lumbroso Marco Rispoli

    9. Optic nerve head diurnal vessel density variations in glaucoma and ocular hypertension measured by optical coherence tomography angiography

      Explore Home - Springer Ophthalmology
      Optic nerve head diurnal vessel density variations in glaucoma and ocular hypertension measured by optical coherence tomography angiography

      Background/aims To evaluate diurnal variations in optic nerve head (ONH) vessel density assessed by optical coherence tomography angiography (OCT-A) in healthy subjects, ocular hypertension (OHT), and open-angle glaucoma (OAG) patients. Methods Forty subjects (OAG, 21; OHT, 6; healthy, 13) were assessed for vessel density percentage (VD%) and flow index in the ONH (NH VD%, NH index), and in the radial peripapillary capillary layer (RPC VD%, RPC index) at 9:00, 11:00, 14:00, 16:00, and 18:00 on a single day. Repeated measures ANOVAs were used to test for changes in the parameters measured at multiple time ...

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      Mentions: Mount Sinai School of Medicine Indiana University

    10. INS-fOCT: a label-free, all-optical method for simultaneously manipulating and mapping brain function

      Explore SPIE Digital Library Neurology
      INS-fOCT: a label-free, all-optical method for simultaneously manipulating and mapping brain function

      Significance: Current approaches to stimulating and recording from the brain have combined electrical or optogenetic stimulation with recording approaches, such as two-photon, electrophysiology (EP), and optical intrinsic signal imaging (OISI). However, we lack a label-free, all-optical approach with high spatial and temporal resolution. Aim: To develop a label-free, all-optical method that simultaneously manipulates and images brain function using pulsed near-infrared light (INS) and functional optical coherence tomography (fOCT), respectively. Approach: We built a coregistered INS, fOCT, and OISI system. OISI and EP recordings were employed to validate the fOCT signals. Results: The fOCT signal was reliable and regional, and the ...

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      Mentions: Oregon Health & Science University Zhejiang University Peng Li

    11. Biomarkers in Usher syndrome: ultra-widefield fundus autofluorescence and optical coherence tomography findings and their correlation with visual acuity and electrophysiology findings

      Explore Home - Springer Ophthalmology
      Biomarkers in Usher syndrome: ultra-widefield fundus autofluorescence and optical coherence tomography findings and their correlation with visual acuity and electrophysiology findings

      Purpose To investigate the functional and structural biomarkers and their correlation with Usher syndrome (USH). Methods Medical records, imaging and electrophysiology test results of USH patients attending the Save Sight Institute between 2012 and 2017 were reviewed. Best corrected visual acuity (BCVA), ultra-widefield autofluorescence (UW-FAF), spectral-domain optical coherence tomography (SD-OCT), full-field electroretinogram and pattern electroretinogram (pERG) were performed. SD-OCT scans assessed central macular thickness (CMT), greatest linear diameter of preserved outer retinal layers—macular island (MI) and presence of cystoid macular edema (CME). UW-FAF images were qualitatively graded to identify hypo/hyperfluorescence patterns in the peripheral fundus. Results Thirty-six eyes ...

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    12. Researchers find additional uses for OCT, ERG technologies

      Explore Healio.com Ophthalmology
      Researchers find additional uses for OCT, ERG technologies

      Research continues to reveal additional uses for evolving technology in the realm of OCT and ERG. These diagnostic tools offer eye care providers noninvasive means to determine signs and features of retinal impairment to better inform prognosis and treatment. Details from a cross-sectional study published in Ophthalmology showed that patients with OCT images displaying a shallow, irregular retinal pigment epithelium elevation (SIRE) sign had a higher risk for nonexudative macular neovascularization (NE-MNV) and neovascular age-related macular degeneration. “SIRE can be detected on the more ubiquitously available structural OCT B-scans and indicate eyes at higher risk of NE-MNV and, thus, subsequently ...

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      Mentions: Optovue Alcon

    13. Comparison of neointimal coverage between ultrathin biodegradable polymer‐coated sirolimus‐eluting stents and durable polymer‐coated everolimus‐eluting stents: 6 months optical coherence tomography follow‐up from the TAXCO study

      Explore Wiley Online Library Cardiology
      Comparison of neointimal coverage between ultrathin biodegradable polymer‐coated sirolimus‐eluting stents and durable polymer‐coated everolimus‐eluting stents: 6 months optical coherence tomography follow‐up from the TAXCO study

      Aim The TAXCO study was designed to compare the degree of neointimal coverage and the prevalence of malapposition at 6 months subsequent to implantation of ultrathin biodegradable polymer‐coated sirolimus‐eluting stents (SES) and durable polymer‐coated everolimus‐eluting stents (EES) of thin strut thickness using optical coherence tomography (OCT). Methods The TAXCO study included a total of 42 patients who gave consent and underwent OCT examination between August 2017 and September 2017. Of 42, five patients' OCT examinations were of insufficient quality for quantitative analysis. Thus, the OCT analysis group consisted of 37 patients. Among them, 16 patients were ...

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      Mentions: National Institutes of Health Abbot

    14. Comparison Between Two SS-OCT Biometry

      Explore Home - ClinicalTrials.gov Clinical Trials
      Comparison Between Two SS-OCT Biometry

      Since recently a second swept-source optical coherence tomography (ss-OCT) optical biometry device was launched (Anterion, Heidelberg Engineering). Aim of this study is a retrospective data collection of patients who were measured with both ss-OCT optical biometry devices and to assess the limits of agreement of the two devices. Retrospective comparison of two ss-OCT biometry devices concerning comparability of measurements of axial eye length, anterior chamber depth, lens thickness and keratometry

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      Mentions: Heidelberg Engineering Carl Zeiss Meditec
      16. See all articles
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    An open-source robotic platform that enables automated monitoring of replicate biofilm cultivations using optical coherence tomography Spectroscopic optical coherence refraction tomography NIR-II dual-modal optical coherence tomography and photoacoustic imaging-guided dose-control cancer chemotherapy Open Rank Tenure Track Faculty Position in Retina Research, University of Rochester, Rochester, NY NTU scientists develop handheld, high-resolution medical imaging device COMPARISON OF POST STENT OPTICAL COHERENCE TOMOGRAPHY FINDINGS AMONG THREE SUBTYPES OF CALCIFIED CULPRIT PLAQUES IN PATIENTS WITH ACUTE CORONARY SYNDROME Three‐dimensional mapping of the attenuation coefficient in optical coherence tomography to enhance breast tissue micro‐architecture contrast Novel Tunable Lasers for Optical Coherence Tomography: Marie Curie Early Stage Positions to train towards PhD in an European Innovative Training Network PhotoniCare Announces Nishant Mohan as their New Chief Technology and Product Officer ZEISS Medical Technology Announces Changes in Ophthalmic Devices Executive Leadership Optical Coherence Tomography Angiography of Idiopathic Foveal Hypoplasia and Its Correlation With Visual Acuity Optical coherence tomography/angiography-guided tumor ablation with a continuous-wave laser diode

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    1. In ophthalmology we have a wealth of eye images—fundus photographs, optical coherence tomography (OCT), etc.—that are fundamental to the diagnosis, monitoring, and treatment of a number of eye diseases, so this field is ideally suited for deep learning applications.
      By Felipe A. Medeiros
    2. We are delighted to have received MHLW approval of the Novasight Hybrid system. Clinical data in the past several years has increasingly demonstrated that intravascular imaging with either IVUS or OCT has significant potential to improve outcomes in the large number of patients being treated with angioplasty and stenting for coronary artery disease. However, there are substantial differences between the images generated by these two technologies. Until now, physicians in Japan have had to choose between IVUS or OCT when performing percutaneous coronary interventions (PCI). We are delighted that Conavi and Japan Lifeline can now begin to offer both of these highly complementary imaging techniques on a single catheter to physicians in Japan.
      By Brian K. Courtney
    3. It is such a huge honor to be recognized with this prestigious industry award for best healthcare product in 2020, and we’d like to thank SPIE and Photonics Media for sponsoring this incredible opportunity...Our team is working hard to provide better options to millions of patients who suffer from middle ear infections. Following our recent 510(k) clearance from the FDA, we cannot wait to see how the TOMi Scope impacts the standard of care for this incredibly common disease.
      By Ryan L. Shelton
    4. We developed an algorithm that can be used to automatically analyze optical coherence tomography (OCT) images of the retina to predict whether a patient is likely to respond to anti-VEGF treatments...This research represents a step toward precision medicine, in which such predictions help clinicians better select first-line therapies for patients based on specific disease conditions.
      By Sina Farsiu
    5. This milestone marks the first step towards establishing physician and patient reimbursement for our home OCT pipeline technology...We applaud the AMA’s CPT Editorial panel for establishing codes for billing remote diagnostic services and patient home monitoring services. We believe that a home-based OCT will be the future of monitoring patients with wet AMD, one that allows doctors to individualize their patients’ treatment.
      By Kester Nahen
    6. We hope that this new lab between SNEC-SERI and NTU will be the start of an important programme to utilise engineering solutions to help and improve care of our patients with eye problems.
      By Tin Aung
    7. “At PhotoniCare we set out to solve the massive problem of frequent misdiagnosis of middle ear infections, and the overuse of antibiotics and referrals to surgery in children that result...We thank the FDA for clearing our TOMi Scope under a new product code unique to our technology, and look forward to bringing this innovation to doctors and patients very soon.”
      By Ryan L. Shelton
    8. The move to the new office space on Fox Drive has been exciting, to say the least...Part of the move includes a build out of a portion of the office space. So the #EnginEarGuys got to try our hand at interior design! Much of the design, however, was spearheaded by one of PhotoniCare’s engineers, Heather Howard. She helped the team navigate the moving process and make decisions on everything from our new manufacturing layout to the aesthetics – carpet, paint, and furniture!
      By Ryan L. Shelton
    9. “Our group has spent quite a few years working on developing the underlying imaging technology...This grant will support our translational efforts and allow us to identify ophthalmic surgeries that will directly benefit from real-time guidance and to better understand how surgical maneuvers impact postoperative visual function.
      By Yuankai K. Tao
    10. An historic issue with OCT is that the depth resolution is typically several times better than the lateral resolution...If the layers of imaged tissues happen to be horizontal, then they're well defined in the scan. But to extend the full power of OCT for live imaging of tissues throughout the body, a method for overcoming the tradeoff between lateral resolution and depth of imaging was needed.
      By Joseph A. Izatt