1. Featured Articles

    1. Metasurface-based focus-tunable mirror

      Explore OSA | OSA Publishing Probes
      Metasurface-based focus-tunable mirror

      Varifocal mirrors, which have various applications in optical coherent tomography and three-dimensional displays, are traditionally based on the fluid pressure or mechanical pusher to deform the mirror. The limitations of conventional varifocal mirrors are obvious, such as the heavy size of the device and constraints of tunability, due to their mechanical pressure control elements. The reprogrammable metasurface, a new flat photonic device with multifunction in an ultrathin dimension, paves the way towards an ultrathin and lightweight mirror with precise phase profile. Here, an active reconfigurable metasurface is proposed to achieve the manipulation of the wavefront. The meta-atom in the metasurface ...

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    2. Marie Curie Early Stage Researcher “NExt generation of Tunable LASers for Optical Coherence Tomography”

      Explore Optical Coherence Tomography News Jobs & Studentships
      Marie Curie Early Stage Researcher “NExt generation of Tunable LASers for Optical Coherence Tomography”

      School of Physical Sciences Location: Canterbury Salary: £32,500 Grade: Marie Curie Post Type: Full Time Contract Type: Fixed Term - 36 Months Release Date: Thursday 10 October 2019 Closing Date: 23.59 hours GMT on Monday 30 December 2019 (unless otherwise stated) Reference: STM-074-19 We are recruiting for three PhD Studentships in the fields of Optics and Laser Physics, with emphasis on optical coherence tomography for a period of 36 months with a start date anytime between 1st February 2020 and 31 January 2021, within the Applied Optics Group, School of Physical Sciences. These are supported by the Marie Curie ...

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      Mentions: Université Pierre et Marie Curie University of Kent

    3. Scientific Reports Journal Collection on "Quantitative and Computational Techniques in Optical Coherence Tomography" open for submission

      Explore Optical Coherence Tomography News
      Scientific Reports Journal Collection on "Quantitative and Computational Techniques in Optical Coherence Tomography" open for submission

      Scientific Reports , a Nature Research journal, is welcoming original primary research articles for a special Guest Edited Collection on ‘Quantitative and computational techniques in optical coherence tomography’ (https://www.nature.com/srep/guestedited#optical-coherence-tomography ). This Collection seeks to bring together original Articles which exploit realistic mathematical models of OCT image formation to obtain insight not otherwise available from raw OCT images. This includes research using techniques such as parametric attenuation imaging, local birefringence retrieval, full-wave modelling, computational adaptive optics, flow and displacement measurement, elastography and inverse scattering. Submissions are welcome on a rolling basis. For information regarding Scientific Reports' policies ...

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      Mentions: University College London Peter R. T. Munro

    4. A Deep Learning Approach to Denoise Optical Coherence Tomography Images of the Optic Nerve Head

      Explore Nature Publishing Group Ophthalmology
      A Deep Learning Approach to Denoise Optical Coherence Tomography Images of the Optic Nerve Head

      Optical coherence tomography (OCT) has become an established clinical routine for the in vivo imaging of the optic nerve head (ONH) tissues, that is crucial in the diagnosis and management of various ocular and neuro-ocular pathologies. However, the presence of speckle noise affects the quality of OCT images and its interpretation. Although recent frame-averaging techniques have shown to enhance OCT image quality, they require longer scanning durations, resulting in patient discomfort. Using a custom deep learning network trained with 2,328 ‘clean B-scans’ (multi-frame B-scans; signal averaged), and their corresponding ‘noisy B-scans’ (clean B-scans + Gaussian noise), we were able to ...

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      Mentions: Medical University of Vienna Singapore Eye Research Institute Nanyang Technological University

    5. VISE affiliates awarded $1.8 million grant to improve surgical guidance during eye surgery

      Explore School of Engineering Ophthalmology , Funding
      VISE affiliates awarded $1.8 million grant to improve surgical guidance during eye surgery

      A team of Vanderbilt University engineers and clinicians have won a five-year $1.8 million National Eye Institute grant to develop and translate novel intraoperative imaging technologies to the ophthalmic surgical suite to enable real-time surgical guidance. “Our group has spent quite a few years working on developing the underlying imaging technology,” said Yuankai Kenny Tao, assistant professor of biomedical engineering and a faculty researcher in the Vanderbilt Institute for Surgery and Engineering, is the principal investigator. “This grant will support our translational efforts and allow us to identify ophthalmic surgeries that will directly benefit from real-time guidance and to ...

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      Mentions: Vanderbilt University Yuankai K. Tao

    6. Advances In Intraoperative OCT

      Explore Review of Ophthalmology® > Home Ophthalmology
      Advances In Intraoperative OCT

      Over the past decade, there have been major advances in the field of intraoperative optical coherence tomography. From the development of the portable OCT probe to the first microscope-integrated system, intraoperative OCT has evolved from a research idea to a clinically viable technology. Advances such as heads-up visualization and microscope-integration, as well as the results from large clinical studies, have pushed the field forward. While the feasibility and potential utility of intraoperative optical coherence tomography has been demonstrated both in clinical studies and in real-world usage, several areas of enhancement are needed to enable iOCT to be part of a ...

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      Mentions: Cleveland Clinic Justis P. Ehlers

    7. Co-cultured microfluidic model of the airway optimized for microscopy and micro-optical coherence tomography imaging

      Explore OSA | OSA Publishing Pulmonology
      Co-cultured microfluidic model of the airway optimized for microscopy and micro-optical coherence tomography imaging

      We have developed a human bronchial epithelial (HBE) cell and endothelial cell co-cultured microfluidic model to mimic the in vivo human airway. This airway-on-a-chip was designed with a central epithelial channel and two flanking endothelial channels, with a three-dimensional monolayers of cells growing along the four walls of the channel, forming central clear lumens. These cultures mimic airways and microvasculature in vivo . The central channel cells are grown at air-liquid interface and show features of airway differentiation including tight-junction formation, mucus production, and ciliated cells. Combined with novel micro-optical coherence tomography, this chip enables functional imaging of the interior of ...

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      Mentions: Guillermo J. Tearney Massachusetts General Hospital University of Alabama

    8. Measuring light scattering and absorption in corals with Inverse Spectroscopic Optical Coherence Tomography (ISOCT): a new tool for non-invasive monitoring

      Explore Nature Publishing Group NDE/NDT
      Measuring light scattering and absorption in corals with Inverse Spectroscopic Optical Coherence Tomography (ISOCT): a new tool for non-invasive monitoring

      The success of reef-building corals for >200 million years has been dependent on the mutualistic interaction between the coral host and its photosynthetic endosymbiont dinoflagellates (family Symbiodiniaceae) that supply the coral host with nutrients and energy for growth and calcification. While multiple light scattering in coral tissue and skeleton significantly enhance the light microenvironment for Symbiodiniaceae, the mechanisms of light propagation in tissue and skeleton remain largely unknown due to a lack of technologies to measure the intrinsic optical properties of both compartments in live corals. Here we introduce ISOCT (inverse spectroscopic optical coherence tomography), a non-invasive approach to measure ...

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      Mentions: Northwestern University

    9. Fractional Flow Reserve or Optical Coherence Tomography to Guide Management of Angiographically-Intermediate Coronary Stenosis: A Single-Center Trial

      Explore interventions.onlinejacc.org Cardiology
      Fractional Flow Reserve or Optical Coherence Tomography to Guide Management of Angiographically-Intermediate Coronary Stenosis: A Single-Center Trial

      Background Fractional flow reserve (FFR) and optical coherence tomography (OCT) may help both in assessment of angiographically-intermediate coronary lesions (AICL) and in percutaneous coronary interventions (PCI) optimization. Objectives: To compare OCT-guidance and FFR-guidance in patients with AICL in a single-center, prospective, 1:1 randomized trial (acronym: FORZA, NCT01824030 ). Methods Patients with AICL were randomized to FFR or OCT. In the FFR arm, PCI was performed if FFR was ≤0.80. In the OCT arm, PCI was performed if area stenosis was ≥75% or 50%-75% with minimal lumen area <2.5 mm 2 or plaque rupture. Angina (evaluated by Seattle ...

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      Mentions: Rocco Vergallo

    10. Fully Automatic Artificial Intelligence Diagnostic Model Of Coronary Artery Lesions Using Oct Imaging

      Explore Canadian Journal of Cardiology Cardiology
      Fully Automatic Artificial Intelligence Diagnostic Model Of Coronary Artery Lesions Using Oct Imaging

      Background Coronary artery disease leads to progression of pathological formations in arterial wall layers, which may be followed by acute coronary syndrome. Optical Coherence Tomography has high resolution to visualize intracoronary wall structure. In this study, we aimed to design a computer aided diagnostic model providing clinicians with an operator-independent diagnosis of coronary lesions. Jump to Section Background Methods and Results Conclusion Methods and Results 45 OCT pullbacks obtained from different pediatric patients using ILUMIEN OCT system with ∼100 images per pullback are used in this study. Our proposed coronary diagnostic model starts with evaluating the structural changes of the ...

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    11. OCT-Based Tooth Scan and Reconstruction

      Explore MDPI Open Access Journals Platform Dentistry
      OCT-Based Tooth Scan and Reconstruction

      Digital dental reconstruction can be a more efficient and effective mechanism for artificial crown construction and period inspection. However, optical methods cannot reconstruct those portions under gums, and X-ray-based methods have high radiation to limit their applied frequency. Optical coherence tomography (OCT) can harmlessly penetrate gums using low-coherence infrared rays, and thus, this work designs an OCT-based framework for dental reconstruction using optical rectification, fast Fourier transform, volumetric boundary detection, and Poisson surface reconstruction to overcome noisy imaging. Additionally, in order to operate in a patient’s mouth, the caliber of the injector is small along with its short penetration ...

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      Mentions: National Taiwan University National Yang-Ming University

    12. Intravascular optical coherence tomography method for automated detection of macrophage infiltration within atherosclerotic coronary plaques

      Explore atherosclerosis-journal.com Cardiology
      Intravascular optical coherence tomography method for automated detection of macrophage infiltration within atherosclerotic coronary plaques

      Background and aims Significant macrophages infiltration in advanced atherosclerotic plaques promotes acute coronary events. Hence, the clinical imaging of macrophage content in coronary atherosclerotic plaques could potentially aid in identifying patients most at risk of future acute coronary events. The aim of this study was to introduce and validate a simple intravascular optical coherence tomography (IV-OCT) image processing method for automated, accurate and fast detection of macrophage infiltration within coronary atherosclerotic plaques. Methods This method calculates the ratio of the normalized-intensity standard deviation (NSD) values estimated over two axially-adjacent regions of interest in an IV-OCT cross-sectional image (B-scan). When applied ...

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      Mentions: Javier A. Jo

    13. Postdoctoral Research Associate - Biomedical Optics and Functional Imaging Laboratory at University of Illinois at Chicago

      Explore Optical Coherence Tomography News Jobs & Studentships
      Postdoctoral Research Associate - Biomedical Optics and Functional Imaging Laboratory at University of Illinois at Chicago

      A postdoctoral position is available in the Biomedical Optics and Functional Imaging group with Dr. Xincheng Yao ( yaolab.bioe.uic.edu ) within the Department of Bioengineering, University of Illinois at Chicago. Dr. Yao’s Biomedical Optics and Functional Imaging Laboratory is housed in the Lions of Illinois Eye Research Institute (LIERI), within the same building with UIC Retina Clinic. In collaboration with experienced ophthalmologists and vision scientists, our lab is focusing on new development of ophthalmic instrumentation and imaging technology to advance retinal study, disease diagnosis and treatment evaluation. Our current research includes ultra-wide field fundus photography, functional optical coherence ...

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      Mentions: Xincheng Yao

    14. VIS-OCT Opens Eyes to New Approaches

      Explore Photonics.com
      VIS-OCT Opens Eyes to New Approaches

      First reported in 1991 by Huang and colleagues 1 , OCT has become an important imaging tool for ophthalmology following innovations over the past three decades. OCT noninvasively provides 3D in vivo optical biopsy with microscopic resolution in the eye at a depth range up to the choroid 2 . Besides 3D anatomical imaging, OCT can also provide functional information. The most notable functional extension is OCT angiography (OCTA), which can map the microvasculature in the eye without contrast agent and is being investigated in clinical ophthalmology.

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      Mentions: Northwestern University Hao F. Zhang Opticent Health

    15. OCT and Ophthalmology in the Age of Artificial Intelligence, Tuesday Oct 8, 2019 1:00P EDT

      Explore Photonics.com
      OCT and Ophthalmology in the Age of Artificial Intelligence, Tuesday Oct 8, 2019 1:00P EDT

      This webinar will provide an executive overview for leaders in imaging and ophthalmology on how artificial intelligence (AI) is transforming the field of medical imaging. Presenter Nishant Mohan will provide a hands-on demonstration of how to develop a deep-learning AI system from scratch, giving attendees critical insight into how to use this powerful tool. Separating the hype from reality, Mohan will discuss essential concepts behind the revolutionizing power of AI. In addition, he will present critical factors in the ecosystem that is driving AI technology and major AI platforms. He will provide specific examples of the application of AI in ...

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      Mentions: Wasatch Photonics Nishant Mohan
    16. See all articles

  2. Recent Articles From Around The Web

    1. Efficient supercontinuum generation enabled by dispersion engineering in a dual-core waveguide

      Explore ScienceDirect Broadband Sources
      Efficient supercontinuum generation enabled by dispersion engineering in a dual-core waveguide

      A compact dual-core waveguide is proposed for efficient supercontinuum generation, in which the use of Si-rich nitride and titanium dioxide provides a large enough index contrast for dispersion engineering. Strong anomalous group velocity dispersion is obtained over a wide bandwidth of 1860 nm which greatly reduces the dispersion length. The nonlinear length can also be significantly decreased due to high nonlinear Kerr index of Si-rich nitride. As a consequence, it could facilitate octave-spanning supercontinuum generation from 1160 to 2385 nm in a greatly reduced propagation distance, as short as 165μm . It is more than one order of magnitude shorter ...

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      Mentions: University of Central Florida

    2. 3D Fingerprint Gender Classification Using Deep Learning

      Explore Home - Springer NDE/NDT , Other Non-Medical
      3D Fingerprint Gender Classification Using Deep Learning

      Optical Coherence Tomography (OCT) is a high resolution imaging technology, which provides a 3D representation of the fingertip skin. This paper for the first time investigates gender classification using those 3D fingerprints. Different with current fingerprint gender classification methods, the raw multiple longitudinal( X - Z ) fingertip images of one finger can be applied instead of studying features extracted from fingerprints, and the model can be trained effectively when the training data set is relatively small. Experimental results show that the best accuracy of 80.7% is achieved by classifying left fore finger on a small database with 59 persons. Meanwhile ...

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    3. Transfer Learning for Automated OCTA Detection of Diabetic Retinopathy

      Explore arxiv.org Ophthalmology
      Transfer Learning for Automated OCTA Detection of Diabetic Retinopathy

      Purpose: To test the feasibility of using deep learning for optical coherence tomography angiography (OCTA) detection of diabetic retinopathy (DR). Methods: A deep learning convolutional neural network (CNN) architecture VGG16 was employed for this study. A transfer learning process was implemented to re-train the CNN for robust OCTA classification. In order to demonstrate the feasibility of using this method for artificial intelligence (AI) screening of DR in clinical environments, the re-trained CNN was incorporated into a custom developed GUI platform which can be readily operated by ophthalmic personnel. Results: With last nine layers re-trained, CNN architecture achieved the best performance ...

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      Mentions: Xincheng Yao

    4. Imaging in Neuro-ophthalmology

      Explore LWW Online Neurology , Ophthalmology
      Imaging in Neuro-ophthalmology

      PURPOSE OF REVIEW:This article discusses an approach to imaging in patients with neuro-ophthalmologic disorders, with emphasis on the clinical-anatomic localization of lesions affecting afferent and efferent visual function. RECENT FINDINGS:Advances in MRI, CT, ultrasound, and optical coherence tomography have changed how neuro-ophthalmic disorders are diagnosed and followed in the modern clinical era. SUMMARY:The advantages, disadvantages, and indications for various imaging techniques for neuro-ophthalmologic disorders are discussed, with a view to optimizing how these tools can be used to enhance patient care.

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      Mentions: Fiona E. Costello

    5. Precision Microfabrication of Optical Probes for Intravascular Diagnostics (Thesis)

      Explore UCL Discovery Cardiology , Probes , Student Theses
      Precision Microfabrication of Optical Probes for Intravascular Diagnostics (Thesis)

      This thesis details a collection of design, optimisation, fabrication and characterisation work to form fiber-optic probes and optical phantom devices for intravascular diagnostics in minimally invasive surgery (MIS). Optically generated ultrasound is an emerging technique to create broadband high frequency ultrasound via the photoacoustic effect. In the first segment of this thesis, the development of a novel miniature fiber-optic ultrasound transmitter is detailed. A morphologically controlled coating was formed at the endface of a multimode optical fiber by controlled electrospinning of a carbon-nanotube composite. Efficient optical ultrasound generation was realised, with signal amplitude, bandwidth and device form factor suited to ...

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      Mentions: University College London

    6. Macular thickness measurements of healthy, naïve cynomolgus monkeys assessed with spectral-domain optical coherence tomography (SD-OCT)

      Explore Journals | PLOS Ophthalmology
      Macular thickness measurements of healthy, naïve cynomolgus monkeys assessed with spectral-domain optical coherence tomography (SD-OCT)

      The purpose of this study was to measure central macular thickness in an unprecedented number of cynomolgus monkeys. Macular thickness was measured with Heidelberg spectral-domain OCT in 320 eyes of healthy and treatment-naïve cynomolgus monkeys (80 males and 80 females). The macula was successfully measured in all 320 eyes. Macular thickness was not significantly different between the sexes. The mean central macular thickness was 244 μm (+/- 21 μm). Macular thicknesses in the quadrants were 327 +/-17 μm (temporal inner), 339 +/- 17 μm (inferior inner), 341 +/- 14 μm (superior inner), 341 +/-18 μm (nasal inner), and 299 +/- 20 μm (temporal ...

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    7. Optical Coherence Tomography Guided Antithrombotic Treatment After Endovascular Thrombectomy of the Posterior Circulation

      Explore Home - ClinicalTrials.gov Cardiology , Clinical Trials
      Optical Coherence Tomography Guided Antithrombotic Treatment After Endovascular Thrombectomy of the Posterior Circulation

      Evidence regarding the role of early (<24 hours) antithrombotics post-revascularization with either intravenous thrombolysis (IVT), endovascular thrombectomy (EVT), or a combination of both remains scarce. In 2018 the American Heart Association/American Stroke Association changed their recommendation, stating that the risk of antithrombotic therapy within the first 24 hours after treatment with IVT (with or without EVT) is uncertain. This was changed after data emerged that early antithrombotics may be safe and may improve outcomes in select patients undergoing EVT. Recently our group showed for the first time that significant residual basilar thrombus can exist after EVT despite complete angiographic ...

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      Mentions: Sunnybrook Health Sciences Centre Victor X. D. Yang

    8. Assessment of Anterior Chamber by Ultrasound Biomicroscopy and Anterior Segment Optical Coherence Tomography in Patients with Inflammatory Glaucoma

      Explore SAGE Journals Ophthalmology
      Assessment of Anterior Chamber by Ultrasound Biomicroscopy and Anterior Segment Optical Coherence Tomography in Patients with Inflammatory Glaucoma

      Objective To investigate the clinical indications of ultrasound biomicroscopy (UBM) and anterior segment optical coherence tomography (AS-OCT) in eyes with inflammatory glaucoma. Methods Sixteen patients (16 eyes) with inflammatory glaucoma were analysed retrospectively. All of the subjects underwent UBM and AS-OCT scans, measuring the following parameters: central corneal thickness (CCT), central anterior chamber depth (ACD), angle-opening distance (AOD500), and trabecular-iris angle (TIA500) in four quadrants. Results Both the UBM and AS-OCT generated detailed, high-resolution images of the anterior segments of the eyes with inflammatory glaucoma. Moreover, the UBM and AS-OCT exhibited statistically similar measurement results for all of the indices ...

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    9. Double Interferometer Design for Independent Wavefront Manipulation in Spectral Domain Optical Coherence Tomography

      Explore Nature Publishing Group
      Double Interferometer Design for Independent Wavefront Manipulation in Spectral Domain Optical Coherence Tomography

      Spectral domain optical coherence tomography (SD-OCT) is a highly versatile method which allows for three dimensional optical imaging in scattering media. A number of recent publications demonstrated the technique to benefit from structured illumination and beam shaping approaches, e.g. to enhance the signal-to-noise ratio or the penetration depth with samples such as biological tissue. We present a compact and easy to implement design for independent wavefront manipulation and beam shaping at the reference and sample arm of the interferometric OCT device. The design requires a single spatial light modulator and can be integrated to existing free space SD-OCT systems ...

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      Mentions: University of Hannover

    10. Avinger, Inc.: Avinger Expands US Reach with Seven New Accounts in Third Quarter

      Explore Aktien Cardiology , Other Business News
      Avinger, Inc.: Avinger Expands US Reach with Seven New Accounts in Third Quarter

      Avinger, Inc. (NASDAQ:AVGR), a commercial-stage medical device company marketing the first and only intravascular image-guided, catheter-based system for diagnosis and treatment of Peripheral Artery Disease (PAD), today announced the launch of seven new Lumivascular centers during the third quarter, including sites in the high-volume PAD markets of Florida, Georgia and Arizona. This growth in new accounts is the result of continued expansion of Avinger's sales team and strong market demand for the Company's Pantheris and Pantheris SV image-guided atherectomy products. "We are excited to report the launch of seven new clinical centers using Avinger's best-in-class Lumivascular ...

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      Mentions: Avinger

    11. Short-term variations of optic coherence tomography findings in mild and severe chronic obstructive pulmonary disease

      Explore Nature Publishing Group Ophthalmology
      Short-term variations of optic coherence tomography findings in mild and severe chronic obstructive pulmonary disease

      Objective To evaluate the short-term changes in subfoveal choroidal thickness (SFCT), ganglion cell complex (GCC) analysis, and retinal nerve fiber length (RNFL) of patients with chronic obstructive pulmonary disease (COPD) in a 3-month follow-up. Materials and methods Forty-eight patients with COPD (96 eyes) and 40 control subjects (80 eyes) were enrolled in our study. COPD patients were grouped according to disease severity as Group 1 (mild–moderate) and Group 2 (advanced). GCC, RNFL, and SFCT analysis by Cirrus SD-OCT were obtained for all eyes, in two consecutive examinations with a 3-month interval. Results SFCT in Group 2 was lower than ...

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    12. Dual-angle optical coherence tomography for index of refraction estimation using rigid registration and cross-correlation

      Explore SPIE Digital Library
      Dual-angle optical coherence tomography for index of refraction estimation using rigid registration and cross-correlation

      The index of refraction ( n ) of materials and/or tissues depends on their physical properties and serves as a source of optical contrast in imaging. The variations of the index of refraction have also been investigated for diagnostic purposes in various fields, such as hematology, oncology, etc., since they can signify disease and cell dynamic changes. Optical coherence tomography (OCT) has been used in the past to measure the index ex vivo . However, most methodologies described in the literature are not appropriate for in vivo imaging since they require either a mirror below the sample or a complicated imaging setup ...

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      Mentions: Costas D. Pitris University of Cyprus

    13. Machine learning of retinal pathology in optical coherence tomography images

      Explore Home Ophthalmology
      Machine learning of retinal pathology in optical coherence tomography images

      Background: Acute macular degeneration (AMD), central serous retinopathy (CSR), diabetic retinopathy (DR) and macular hole (MH) are common vision impairing pathologies in the field of ophthalmology. Machine learning with deep convolutional neural networks can be used to analyze ophthalmological diseases using fundus and optical coherence tomography (OCT) images, but with limited accuracy. In order to improve the sensitivity and specificity of these models, the objective of this study was to examine the effect of data augmentation on the performance of the neural network. Methods: OCT Images for above pathologies and normal eye were acquired from the Optical Coherence Tomography Image ...

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      Mentions: University of Cincinnati

    14. Resolution enhancement in low transverse sampling optical coherence tomography angiography using deep learning

      Explore arxiv.org
      Resolution enhancement in low transverse sampling optical coherence tomography angiography using deep learning

      Optical coherence tomography angiography (OCTA) requires high transverse sampling rates for visualizing retinal and choroidal capillaries, which impedes the popularization of the OCTA technique due to the high cost of speedy acquisition systems. On the other hand, current wide-field OCTA using low transverse sampling causes the underestimation of vascular biomarkers in quantitative analysis. In this paper, we propose to use deep learning to repair the resolution degeneration induced by the low transverse sampling. We conducted preliminary experiments on converting the centrally cropped 3 × 3 mm2 field of view (FOV) of the 8 × 8 mm2 foveal OCTA images (a sampling rate ...

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    15. Role of Optical Coherence Tomography in the Prognosis of Vogt–Koyanagi–Harada Disease

      Explore Taylor & Francis Online Ophthalmology
      Role of Optical Coherence Tomography in the Prognosis of Vogt–Koyanagi–Harada Disease

      Purpose : To evaluate the prognostic value of OCT in acute VKH disease Methods : Retrospective series of consecutive VKH patients seen with the first presentation, a minimum follow-up of 1 year and serial OCT imaging. The primary outcome was the clinical activity phase at 1, 2 and 3 years. Results : Among 29 subjects, 7 resolved, 17 became chronic, and 5 developed chronic recurrent VKH. Median RNFL measurement obtained 2 months post-treatment was higher among subjects who developed chronic VKH ( p -value = 0.03) and chronic recurrent disease ( p -value = 0.04). Median CRT 1-week post-treatment was lower among subjects who developed ...

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      Mentions: Singapore Eye Research Institute
      16. See all articles
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  9. Picture Gallery

    Metasurface-based focus-tunable mirror Marie Curie Early Stage Researcher “NExt generation of Tunable LASers for Optical Coherence Tomography” Scientific Reports Journal Collection on "Quantitative and Computational Techniques in Optical Coherence Tomography" open for submission A Deep Learning Approach to Denoise Optical Coherence Tomography Images of the Optic Nerve Head VISE affiliates awarded $1.8 million grant to improve surgical guidance during eye surgery Advances In Intraoperative OCT Co-cultured microfluidic model of the airway optimized for microscopy and micro-optical coherence tomography imaging Measuring light scattering and absorption in corals with Inverse Spectroscopic Optical Coherence Tomography (ISOCT): a new tool for non-invasive monitoring Fractional Flow Reserve or Optical Coherence Tomography to Guide Management of Angiographically-Intermediate Coronary Stenosis: A Single-Center Trial Fully Automatic Artificial Intelligence Diagnostic Model Of Coronary Artery Lesions Using Oct Imaging OCT-Based Tooth Scan and Reconstruction Intravascular optical coherence tomography method for automated detection of macrophage infiltration within atherosclerotic coronary plaques

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    1. “Our group has spent quite a few years working on developing the underlying imaging technology...This grant will support our translational efforts and allow us to identify ophthalmic surgeries that will directly benefit from real-time guidance and to better understand how surgical maneuvers impact postoperative visual function.
      By Yuankai K. Tao
    2. An historic issue with OCT is that the depth resolution is typically several times better than the lateral resolution...If the layers of imaged tissues happen to be horizontal, then they're well defined in the scan. But to extend the full power of OCT for live imaging of tissues throughout the body, a method for overcoming the tradeoff between lateral resolution and depth of imaging was needed.
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    7. We are very pleased with the outcomes of this study, which are the culmination of hard work by 47 physicians across 18 collaborating hospitals...What is further encouraging is that this study was undertaken without key technological improvements that have since been launched commercially. We anticipate that future studies using the Real-time Targeting laser marking feature and our newly launched artificial intelligence software, Intelligent Real-time Image Segmentation, will improve upon these already very positive results. Working together with our commercial partner, Merit Medical, and many of the leading hospitals in the United States, we are ecstatic that this technology continues to have an important and beneficial impact for patients.
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