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  1. Feature Of The Week

    Optical Coherence Tomography continues to make tremendous progress in the diagnosis and treatment of coronary artery disease and second generation systems have accelerated that progress. The Thoraxcenter has been a leading organizations in this field as can be seen by clicking the Cardiology tag an scrolling down to "Organizations in the News". Described below is some recent work by Nico Bruining et al which discusses fully automatic three-dimensional quantitative analysis of intracoronary OCT.

    Coronary artery disease (CAD) is one of the most diagnosed pathologies in humans and still one of the leading causes of death. Although great progress has been made in treatment of CAD, for both acute interventions as well as pharmacological treatment, there is still much room for further improvements. Research in this area is heavily depending on coronary artery imaging and to study into detail coronary atherosclerosis mostly intracoronary imaging methods are applied. Until recently intracoronary ultrasound (ICUS) was the de-facto imaging method of choice for studies in which new interventional techniques (e.g. new stent designs) and/or pharmacological treatments (e.g. atherosclerosis progression-regression) were applied. See the rest of this article HERE.

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  3. Recent Articles From Around The Web

    1. Edema of the Photoreceptor Layer in Vogt-Koyanagi-Harada Disease Observed Using High-Resolution Optical Coherence Tomography

      Explore Article 대한안과학회 (1 hour, 1 minute ago) Ophthalmology

      Purpose: To evaluate the characteristics of fluid accumulation in the uveitic stage of Vogt-Koyanagi-Harada (VKH) disease using high resolution optical coherence tomography (OCT3). Methods: Twenty-eight eyes in 14 patients with VKH disease were reviewed retrospectively. These 28 eyes were divided into 19 eyes with intraretinal fluid (C group) and 9 eyes without intraretinal fluid (N group). Changes in visual acuity and fluid accumulation observed using OCT were compared between the two groups. Results: Visual acuity ... (Read Full Article)

      Comment on Article

    2. Refractive Prescription Using Optical Coherence Tomography (Wo 2009/080331)

      Explore Article wipo.int (Jul 2 2009) Ophthalmology , Patents

      Refractive Prescription Using Optical Coherence Tomography (Wo 2009/080331) An optical coherence tomography apparatus and method for measuring refractive power of the human cornea is disclosed. The apparatus collects both the specularly reflected light from the anterior surface of the cornea and diffusely reflected light from the interior of the cornea. The combined refractive power of both surfaces of the cornea is determined. (Read Full Article)

      Comment on Article Mentions:   Scott A. Meyer   Carl Zeiss Meditec

    3. Fundus Autofluorescence in Type 2 Idiopathic Macular Telangiectasia: Correlation with Optical Coherence Tomography and Microperimetry

      Explore Article American Journal of Ophthalmology (Jul 1 2009) Ophthalmology

      Purpose: To use multiple imaging methods to investigate patients with type 2 idiopathic macular telangiectasia (IMT) at different disease severity stages so as to characterize and categorize disease progression through the full spectrum of disease phenotypes.Design: Observational case series.Methods: Twelve patients with type 2 IMT (22 eyes) examined with fundus photography, angiography, optical coherence tomography imaging, fundus autofluorescence (FAF), and microperimetry testing in an institutional setting.Results: Eyes examined by multiple imaging methods were classified into ... (Read Full Article)

      Comment on Article Mentions:   National Eye Institute

    4. Spectral domain phase microscopy (sdpm) dual mode imaging systems and related methods and computer program products

      Explore Article PatFT » Page 1 of 1 (Jun 30 2009) Patents

      Some embodiments of the present invention provide optical coherence tomography systems including an OCT engine and a processor. The OCT engine is configured to provide both standard OCT imaging and spectral domain phase microscopy (SDPM) imaging. The processor is coupled to the OCT engine and is configured to use a first signal processing method when the OCT engine is configured to provide standard OCT imaging and a second signal processing method when the OCT engine ... (Read Full Article)

      Comment on Article Mentions:   Joseph A. Izatt   Eric L. Buckland   Bioptigen

    5. Light source for swept source optical coherence tomography based on cascaded distributed feedback lasers with engineered band gaps

      Explore Article PatFT » Page 1 of 1 (Jun 30 2009) Patents , Tunable Sources

      The present invention is a tunable semiconductor laser for swept source optical coherence tomography, comprising a semiconductor substrate; a waveguide on top of said substrate with multiple sections of different band gap engineered multiple quantum wells (MQWs); a multiple of distributed feedback (DFB) gratings corresponding to each said band gap engineered MWQs, each DFB having a different Bragg grating period; and anti-reflection (AR) coating deposited on at least the laser emission facet of the laser ... (Read Full Article)

      Comment on Article Mentions:   Carl Zeiss Meditec

    6. Device for treating vulnerable plaque

      Explore Article PatFT » Page 1 of 1 (Jun 30 2009) Cardiology , Patents

      A method of treating vulnerable plaque comprising intentionally damaging or rupturing the vulnerable plaque using a wingless balloon which is inflated from a wingless unexpanded diameter to a limited expanded diameter. This process produces significant increase in ECM synthesis at the site of the damage or rupture. As a result, the method strengthens the vulnerable plaque while minimizing or avoiding damage to the surrounding wall of the body lumen or damaging a stable plaque mistakenly ... (Read Full Article)

      Comment on Article Mentions:   Advanced Cardiovascular Systems

    7. Macular and Nerve Fiber Layer Thickness in Amblyopia: The Sydney Childhood Eye Study

      Explore Article OphSource (Jun 28 2009) Ophthalmology

      Purpose: To examine macular and peripapillary retinal nerve fiber layer (RNFL) thickness in amblyopia.Design: Population-based cross-sectional study.Participants: Of 4118 children examined in the Sydney Childhood Eye Study (incorporating the Sydney Myopia Study) from 34 randomly selected primary schools and 21 secondary schools from 2003 to 2005, 3529 (85.7%) were included in this analysis. The median age of the 2 samples was 6 years (n = 1395) and 12 years (n = 2134), respectively.Methods: A detailed ... (Read Full Article)

      Comment on Article Mentions:   Zeiss Stratus OCT   Carl Zeiss Meditec   Paul Mitchell

    8. Optical coherence tomography is less sensitive than visual evoked potentials in optic neuritis

      Explore Article Neurology (Jun 28 2009) Ophthalmology

      Objectives: Determine the utility of optical coherence tomography (OCT) to detect clinical and subclinical remote optic neuritis (ON), its relationship to clinical characteristics of ON and visual function, and whether the retinal nerve fiber layer (RNFL) thickness functions as a surrogate marker of global disease severity. Methods: Cross-sectional study of 65 subjects with at least 1 clinical ON episode at least 6 months prior. Measures included clinical characteristics, visual acuity (VA), contrast sensitivity (CS), OCT, ... (Read Full Article)

      Comment on Article Mentions:   Washington University in St. Louis

    9. Feature Of The Week: 6/28/09: Fully Automatic Three-Dimensional (3D) Quantitative Analysis of Intracoronary Optical Coherence Tomography: Method and Validation

      Explore Article Optical Coherence Tomography News (Jun 27 2009) Cardiology

      Feature Of The Week: 6/28/09: Fully Automatic Three-Dimensional (3D) Quantitative Analysis of Intracoronary Optical Coherence Tomography: Method and Validation Feature Of The Week: 6/26/09: Optical Coherence Tomography continues to make tremendous progress in the diagnosis and treatment of coronary artery disease and second generation systems have accelerated that progress. The Thoraxcenter has been a leading organizations in this field as can be seen by clicking the Cardiology t (Read Full Article)

      Comment on Article Mentions:   Thoraxcenter at Erasmus University Medical Center   Nico Bruining   LightLab Imaging

    10. BS/MS Research Associate - Ocular Imaging at Novartis

      Explore Article CareerBuilder.com Jobs (Jun 27 2009) Jobs & Studentships

      We are seeking a highly motivated scientist with experience in ocular imaging technologies or electrophysiology to join the Ophthalmology Pharmacology group of the Novartis Institutes for Biomedical Research (NIBR) in Cambridge, MA. Primary responsibilities will include animal model characterization employing techniques such as ERG, optical coherence tomography (OCT), scanning laser ophthalmoscopy (SLO) and confocal microscopy.The ideal candidate will have a B.S. or M.S. in Biophysics, Biomedical Engineering, Physiology, Vision Science, Pharmacology, or a related field ... (Read Full Article)

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    11. Refractive Surgery: Advanced optical coherence tomography an integral diagnostic tool

      Explore Article Modern Medicine (Jun 27 2009) Ophthalmology

      Refractive Surgery: Advanced optical coherence tomography an integral diagnostic tool Retinal optical coherence tomography (OCT) is on its way to becoming the next "must-have" tool for preoperative examination of refractive surgery candidates. Spectral-domain OCT (SD-OCT) devices, such as a particular device (3D-OCT, Topcon Medical Systems), enable clinicians to see anatomic features and abnormalities that cannot be visualized with other routine screening technologies, said Daniel S. Durrie, MD, a refractive surgeon in Overland Park, KS (Read Full Article)

      Comment on Article Mentions:   Topcon Medical Systems   Daniel S. Durrie

    12. Datasheet: SU-LDH Digital Line Scan Camera

      Explore Article Photonics Online (Jun 27 2009) Other Business News

      The new SU-LDH-1.7 Linear Digital High speed InGaAs Camera increases line rates for 1024 pixels to over 46,000 lines per second for spectral-domain optical coherence tomography (SD-OCT), NIR spectroscopy and machine vision. This versatile high speed camera provides 14-bit digital capture into base format Camera Link® interface cards. It utilizes the new LC series of linear arrays, which feature double-sampling, integrate-whileread acquisition and low noise, delivering the high dynamic range demanded by these applications. The ... (Read Full Article)

      Comment on Article Mentions:   Sensors Unlimited

    13. The Supercontinuum Laser Source: Fundamentals with Updated References

      Explore Article Springer US (Jun 27 2009) Broadband Sources , Textbooks

      The Supercontinuum Laser Source: Fundamentals with Updated References Photonics and nonlinear optics are important areas of science, engineering and technology. One of the most important ultrafast nonlinear optical processes is the supercontinuum (SC) – the production of intense white light pulses covering: uv, visible, NIR, MIR, and IR. It is produced using ultrashort laser pulses (ps/fs) to produce the ultrabroad band of frequencies. This book covers the fundamental principles and surveys research of current thinkers and experts in the field with updated references ... (Read Full Article)

      Comment on Article Mentions:   City University of New York   Robert R. Alfano

    14. Repeatability and Reproducibility of Macular Thickness Measurements Using Fourier Domain Optical Coherence Tomography

      Explore Article bentham.org (Jun 26 2009) Ophthalmology

      Aim: To evaluate repeatability and reproducibility of macular thickness measurements in visually normal eyes using the Topcon 3D OCT-1000. Methods: Phase 1 investigated scan repeatability, the effect of age and pupil dilation. Two groups (6 younger and 6 older participants) had one eye scanned 5 times pre and post- dilation by 1 operator. Phase 2 investigated between-operator, within and between-visit reproducibility. 10 participants had 1 un-dilated eye scanned 3 times on 2 separate visits by ... (Read Full Article)

      Comment on Article Mentions:   Topcon Medical Systems   Topcon OCT-1000

    15. Interobserver agreement for the detection of optical coherence tomography features of neovascular age-related macular degeneration

      Explore Article iovs.org (Jun 26 2009) Ophthalmology

      Purpose. To investigate the inter-observer agreement for the detection of optical coherence tomography (OCT) features of disease activity in patients with neovascular age-related macular degeneration (nAMD). Method. A cross-sectional agreement study with grading of OCT line scans from patients with nAMD prior to receiving treatment conducted by 2 retinal specialists. Scans were graded for the presence of features of nAMD disease activity (intra-retinal cysts, IRC; subretinal fluid, SRF; diffuse retinal edema, DRE; retinal pigment epithelial ... (Read Full Article)

      Comment on Article Mentions:   Adnan Tufail   Praveen J. Patel

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