1. Featured Articles

    1. ZEISS Marks Milestone for its New North America High Tech Site in Dublin, California

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      ZEISS Marks Milestone for its New North America High Tech Site in Dublin, California

      The internationally leading optics and optoelectronics technology enterprise ZEISS completed the “steel topping out” phase of its new high tech site in the San Francisco Bay Area. The new site in Dublin is an integral part of ZEISS’ global investment strategy and is one element in a string of international projects aimed at expanding, modernizing and realigning sites that ZEISS has been implementing in locations such as Germany, Europe and Asia since 2011. “Our investments are focused on leveraging the existing potential in our growth markets,” explains Dr. Christian Mueller, Member of the Executive Board and CFO of the ZEISS ...

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      Mentions: Carl Zeiss Meditec

    2. Using Optical Coherence Tomography to Make Needle Biopsies Safer

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      Using Optical Coherence Tomography to Make Needle Biopsies Safer

      Stereotactic needle biopsy continues to be widely employed in the diagnosis of intracranial lesions. Despite an overall low complication rate, hemorrhage remains one the most common and potentially serious risks of the procedure. Previous series have reported a symptomatic hemorrhage rate of 3% to 6%, with a minority requiring craniotomy and hemorrhage evacuation. 1-4 Though certain factors inherent to the lesion or the patient have been known to increase hemorrhage risk, 2 , 3 up until this point there has been little that surgeons can do intraoperatively to avoid hemorrhage after a trajectory has been selected. A new report in Science ...

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      Mentions: Brigham and Women’s Hospital Harvard University

    3. Identification of Retinal Biomarkers in Alzheimer’s Disease Using Optical Coherence Tomography: Recent Insights, Challenges, and Opportunities

      Explore MDPI Open Access Journals Platform Ophthalmology
      Identification of Retinal Biomarkers in Alzheimer’s Disease Using Optical Coherence Tomography: Recent Insights, Challenges, and Opportunities

      This review will highlight recent insights into measuring retinal structure in Alzheimer’s disease (AD). A growing body of evidence indicates that disturbances in retinal blood flow and structure are related to cognitive function, which can severely impair vision. Optical coherence tomography (OCT) is an optical imaging technology that may allow researchers and physicians to gain deeper insights into retinal morphology and clarify the impact of AD on retinal health and function. Direct and noninvasive measurement of retinal morphology using OCT has provided useful diagnostic and therapeutic indications in several central nervous system (CNS) diseases, including AD, multiple sclerosis, and ...

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      Mentions: University of Miami Delia Cabrera DeBuc

    4. Senior Scientist on Topcon Milpitas California

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      Senior Scientist on Topcon Milpitas California

      Overview Topcon is a comprehensive ophthalmic device manufacturer within the worldwide ophthalmic community. It introduced the world’s first commercial back-of-the-eye spectral domain (SD) and swept source (SS) optical coherence tomography (OCT) systems, which have driven innovation in eye-care. More recently, Topcon Healthcare Solutions started to enhance not only its hardware but also its software solutions. To become the leader in diagnostic software, Topcon has developed a new strategic division whose primary objective is to create world-class software solutions for the eye-care industry and beyond. Our products enable the collection and visualization of a wide range of imaging and clinical ...

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      Mentions: Topcon Medical Systems

    5. International Ocular Circulation Society Inaugural Meeting, August 10, 2019 Portland Oregon

      Explore Optical Coherence Tomography News Ophthalmology
      International Ocular Circulation Society Inaugural Meeting, August 10, 2019 Portland Oregon

      The International Ocular Circulation Society (IOCS) was co-founded by a group of leading researchers in America, Asia, and Europe in 2018. The inaugural meeting of the new Society will be hosted by David Huang, M.D. and Yali Jia, Ph.D. of the Casey Eye Institute in Portland Oregon on August 10, 2019. The meeting will present 28 papers and 35 posters on technologies on the topics of imaging and measurement of ocular blood flow and oxygen metabolism, vascular anatomy and physiology, and the roles of ocular circulation in retina, optic nerve, neurological, and systemic diseases. The Oregon Health & Science ...

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      Mentions: David Huang Oregon Health & Science University Center for Ophthalmic Optics and Lasers

    6. ZEISS Ophthalmic Digital Summit 2019

      Explore LMC Creative Ophthalmology , Other Business News
      ZEISS Ophthalmic Digital Summit 2019

      In partnership with ODwire, Carl Zeiss Meditec, Inc. and Carl Zeiss Vision invite you to the ZEISS Ophthalmic Digital Summit 2019 . This two-day complimentary program offers live sessions and an interactive product showcase—all within a virtual exhibit hall—designed to provide you with the latest technology innovations and clinical solutions for your practice. Taught by industry leaders , you'll get trained and informed on how the Integrated Diagnostic Imaging platform and ZEISS leading imaging technologies will help shape the future of your practice. Event attendees will also be eligible for special show promotions and discounts on ZEISS instruments.

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      Mentions: Carl Zeiss Meditec

    7. Bacterial Density and Biofilm Structure Determined by Optical Coherence Tomography

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      Bacterial Density and Biofilm Structure Determined by Optical Coherence Tomography

      Optical-coherence-tomography (OCT) is a non-destructive tool for biofilm imaging, not requiring staining, and used to measure biofilm thickness and putative comparison of biofilm structure based on signal intensity distributions in OCT-images. Quantitative comparison of biofilm signal intensities in OCT-images, is difficult due to the auto-scaling applied in OCT-instruments to ensure optimal quality of individual images. Here, we developed a method to eliminate the influence of auto-scaling in order to allow quantitative comparison of biofilm densities in different images. Auto- and re-scaled signal intensities could be qualitatively interpreted in line with biofilm characteristics for single and multi-species biofilms of different strains ...

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    8. Handheld spectrally encoded coherence tomography and reflectometry for motion-corrected ophthalmic optical coherence tomography and optical coherence tomography angiography

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      Handheld spectrally encoded coherence tomography and reflectometry for motion-corrected ophthalmic optical coherence tomography and optical coherence tomography angiography

      Optical coherence tomography (OCT) is the gold standard for quantitative ophthalmic imaging. The majority of commercial and research systems require patients to fixate and be imaged in a seated upright position, which limits the ability to perform ophthalmic imaging in bedridden or pediatric patients. Handheld OCT devices overcome this limitation, but image quality often suffers due to a lack of real-time aiming and patient eye and photographer motion. We describe a handheld spectrally encoded coherence tomography and reflectometry (SECTR) system that enables simultaneous en face reflectance and cross-sectional OCT imaging. The handheld probe utilizes a custom double-pass scan lens for ...

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      Mentions: Vanderbilt University Yuankai K. Tao

    9. Laser cleaning of paintings: in situ optimization of operative parameters through non-invasive assessment by optical coherence tomography (OCT), reflection FT-IR spectroscopy and laser induced fluorescence spectroscopy (LIF)

      Explore Heritage Science Art , NDE/NDT
      Laser cleaning of paintings: in situ optimization of operative parameters through non-invasive assessment by optical coherence tomography (OCT), reflection FT-IR spectroscopy and laser induced fluorescence spectroscopy (LIF)

      Nowadays the use of laser technology as a highly precise tool for the cleaning of paintings is gaining ground. The development of a non-invasive analytical protocol aimed at thorough assessment of the treated surfaces and real time monitoring of the laser cleaning action is thus becoming imperative. This ensures that no side effects (e.g. discoloration, darkening, blackening) will occur on the painting surfaces due to laser ablation. In the present study the potential of the combined use of optical coherence tomography (OCT) and reflection FT-IR spectroscopy for in situ non-invasive assessment of laser cleaning procedures has been investigated on ...

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      Mentions: Nicolaus Copernicus University Piotr Targowski Marcin Sylwestrzak

    10. Spatiotemporal Tracking of Brain-Tumor-Associated Myeloid Cells in Vivo through Optical Coherence Tomography with Plasmonic Labeling and Speckle Modulation

      Explore ACS Publications Home Page Neurology
      Spatiotemporal Tracking of Brain-Tumor-Associated Myeloid Cells in Vivo through Optical Coherence Tomography with Plasmonic Labeling and Speckle Modulation

      By their nature, tumors pose a set of profound challenges to the immune system with respect to cellular recognition and response coordination. Recent research indicates that leukocyte subpopulations, especially tumor-associated macrophages (TAMs), can exert substantial influence on the efficacy of various cancer immunotherapy treatment strategies. To better study and understand the roles of TAMs in determining immunotherapeutic outcomes, significant technical challenges associated with dynamically monitoring single cells of interest in relevant live animal models of solid tumors must be overcome. However, imaging techniques with the requisite combination of spatiotemporal resolution, cell-specific contrast, and sufficient signal-to-noise at increasing depths in tissue ...

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      Mentions: Stanford University Adam de la Zerda Elliott D. SoRelle
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  2. Recent Articles From Around The Web

    1. Image contrast correction method in full-field optical coherence tomography

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      Image contrast correction method in full-field optical coherence tomography

      An image contrast correction method is proposed for en face images obtained with full-field optical coherence tomography (FFOCT). First, the mechanism of image contrast decrease in FFOCT is considered and the theoretical models of main parameters that degrade image contrast are analyzed. Second, changes of contrast with depth are calculated under various conditions, from which the main parameters that affect contrast in tissue are identified. Then based on the analysis, the methods are proposed for correcting image contrast. Finally, the en face tomographic images of human liver tissue at different depths with and without contrast correction are presented to demonstrate ...

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      Mentions: Wanrong Gao Nanjing University of Science and Technology

    2. Evaluation of posterior vitreous detachment using ultrasonography and optical coherence tomography

      Explore Wiley Online Library Ophthalmology
      Evaluation of posterior vitreous detachment using ultrasonography and optical coherence tomography

      Purpose To compare the diagnostic ability of ultrasonography (US) and optical coherence tomography (OCT) in evaluating posterior vitreous detachment (PVD) status. Methods In total, 124 eyes in 63 patients were prospectively enrolled. Posterior vitreous detachment (PVD) status was evaluated by two examiners independently using US and OCT (transverse scan with/without peripapillary scan). By combining all examination results from both examiners, a final agreement on the PVD status was made. Inter‐observer agreement and inter‐examination agreement on PVD detection were evaluated. Results The inter‐observer agreement on PVD grading based on US was substantial (kappa = 0.628). The inter ...

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    3. Optical coherence tomography angiography characteristics of acute retinal arterial occlusion

      Explore BMC Ophthalmology Ophthalmology
      Optical coherence tomography angiography characteristics of acute retinal arterial occlusion

      Background To characterize the vascular changes in eyes within the acute phase of retinal arterial occlusion (RAO) by optical coherence tomography angiography (OCT-A) imaging. Methods This was a retrospective, observational study. Nineteen patients with RAO (symptom onset within 7 days) and 19 age and sex-matched normal control individuals were included. A comprehensive ophthalmic examination and OCT-A examination were conducted for all the patients. Results The vessel density of the superficial capillary plexus (SCP), deep capillary plexus (DCP), and area with a width of 300 μm around the FAZ (FD-300) was significantly reduced in RAO patients compared with that in the ...

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      Mentions: Jing Xu

    4. Computed Tomography–Mediated Registration of Trapeziometacarpal Articular Cartilage Using Intraarticular Optical Coherence Tomography and Cryomicrotome Imaging: A Cadaver Study

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      Computed Tomography–Mediated Registration of Trapeziometacarpal Articular Cartilage Using Intraarticular Optical Coherence Tomography and Cryomicrotome Imaging: A Cadaver Study

      Objective Accurate, high-resolution imaging of articular cartilage thickness is an important clinical challenge in patients with osteoarthritis, especially in small joints. In this study, computed tomography (CT) mediated catheter-based optical coherence tomography (OCT) was utilized to create a digital reconstruction of the articular surface of the trapeziometacarpal (TMC) joint and to assess cartilage thickness in comparison to cryomicrotome data. Design Using needle-based introduction of the OCT probe, the articular surface of the TMC joint of 5 cadaver wrists was scanned in different probe positions with matching CT scans to record the intraarticular probe trajectory. Subsequently and based on the acquired ...

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      Mentions: Academic Medical Center at the University of Amsterdam Ton G. van Leeuwen Daniël M. de Bruin

    5. Successful Treatment of Genital Warts with Ingenol Mebutate Monitored with Optical Coherence Tomography and Reflectance Confocal Microscopy

      Explore KoreaMed Synapse Dermatology
      Successful Treatment of Genital Warts with Ingenol Mebutate Monitored with Optical Coherence Tomography and Reflectance Confocal Microscopy

      Ingenol mebutate (IM) is approved for the treatment of actinic keratosis and induces cell death in precancerous lesions. The efficacy of IM in the treatment of genital warts was investigated in a therapy-refractory patient. The 74-year-old male was treated with IM gel for three consecutive days. Treatment course and efficacy were evaluated by clinical inspection and non-invasive diagnostics namely optical coherence tomography (OCT) and reflectance confocal microscopy (RCM). Within 24 to 48 hours IM induced a strong local inflammatory reaction. One week later a complete response was observed. OCT and RCM showed a strong reaction after treatment with erosions, swelling ...

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      Mentions: Kawasaki Medical School

    6. Comparison of peripapillary and subfoveal choroidal thickness in normal versus primary open-angle glaucoma (POAG) subjects using spectral domain optical coherence tomography (SD-OCT) and swept source optical coherence tomography (SS-OCT)

      Explore Home | BMJ Open Ophthalmology Ophthalmology
      Comparison of peripapillary and subfoveal choroidal thickness in normal versus primary open-angle glaucoma (POAG) subjects using spectral domain optical coherence tomography (SD-OCT) and swept source optical coherence tomography (SS-OCT)

      Objective To elucidate the difference between choroidal thickness (CT) in primary open-angle glaucoma (POAG) and normal subjects and to compare the CT measured using spectral domain optical coherence tomography (SD-OCT) and swept source optical coherence tomography (SS-OCT). Methods and analysis This cross-sectional observational study included 25 eyes of 17 POAG subjects (cases) and 31 eyes of 20 normal subjects (controls). All the patients underwent complete ophthalmologic examination, enhanced depth imaging, SD-OCT and SS-OCT. In both controls and cases, the CT was measured in seven predetermined points in macular and peripapillary area and were compared. Results Choroid was significantly thicker on ...

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      Mentions: L V Prasad Eye Institute Sirisha Senthil

    7. Methods for Quantifying Optic Disc Volume and Peripapillary Deflection Volume Using Radial Optical Coherence Tomography Scans and Association with Intracranial Pressure

      Explore Frontiers Ophthalmology
      Methods for Quantifying Optic Disc Volume and Peripapillary Deflection Volume Using Radial Optical Coherence Tomography Scans and Association with Intracranial Pressure

      Purpose: Papilledema and peripapillary deformation of Bruch’s membrane(BM) are associated with elevated intracranial pressure(ICP). We have developed a novel methodology to measure these parameters using a radial optical coherence tomography(OCT) scan pattern and apply this to test the hypothesis that ICP is associated with volumetric features of ophthalmic structures. Methods: 6-radial OCT B-scans centered over the optic nerve head were acquired in 17 subjects(30 eyes) before lumbar puncture with measurement of ICP(range:10-55 cm H2O). Internal limiting membrane(ILM) and BM were segmented. Three definitions of BM were studied to account for imaging artifact ...

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      Mentions: Stanford University

    8. Disease classification of macular Optical Coherence Tomography scans using deep learning software: validation on independent, multi-centre data

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      Disease classification of macular Optical Coherence Tomography scans using deep learning software: validation on independent, multi-centre data

      Purpose: To evaluate Pegasus-OCT, a clinical decision support software for the identification of features of retinal disease from macula OCT scans, across heterogenous populations involving varying patient demographics, device manufacturers, acquisition sites and operators. Methods: 5,588 normal and anomalous macular OCT volumes (162,721 B-scans), acquired at independent centres in five countries, were processed using the software. Results were evaluated against ground truth provided by the dataset owners. Results: Pegasus-OCT performed with AUROCs of at least 98% for all datasets in the detection of general macular anomalies. For scans of sufficient quality, the AUROCs for general AMD and DME ...

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      Mentions: Cardiff University Kings College London

    9. Optical coherence tomography-based patient-specific coronary artery reconstruction and fluid–structure interaction simulation

      Explore Home - Springer Cardiology
      Optical coherence tomography-based patient-specific coronary artery reconstruction and fluid–structure interaction simulation

      Plaque rupture is related to the mechanical stress it suffered. The value and distribution of the mechanical stress in plaque could help on assessing plaque vulnerability. To look into the stress conditions in the coronary artery, a patient-specific coronary model was created by using optical coherence tomography (OCT) and angiography imaging data. The reconstructed coronary model consisted of the structure of the lumen, the arterial wall and plaque components. Benefited by the high resolution of OCT, detailed structures such as the thin fibrous cap could be observed and built into the geometry. On this reconstructed coronary model, a fully coupled ...

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    10. Optical coherence tomography of the retina, nerve fiber layer, and optic nerve head in dogs with glaucoma

      Explore Wiley Online Library Ophthalmology
      Optical coherence tomography of the retina, nerve fiber layer, and optic nerve head in dogs with glaucoma

      Objective To evaluate the retina and optic nerve head (ONH) in canine eyes predisposed to glaucoma using optical coherence tomography (OCT). Animals Twenty‐five eyes (24 dogs). Methods Measures of peripapillary retinal, retinal nerve fiber layer (RNFL), and ganglion cell complex (GCC) thickness and ONH parameters were obtained in vivo by OCT of the unaffected eye in dogs diagnosed with unilateral primary glaucoma (predisposed; n = 12) and compared with measures of healthy control eyes (normal; n = 13). Repeatability and intrarater reliability were explored using intraclass correlation coefficients (ICC). Results Compared to normal eyes, predisposed eyes had a thinner retina in ...

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      Mentions: University of Sydney

    11. MGH Receives NIH Grant for Quantitative Biomechanics Imaging

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      MGH Receives NIH Grant for Quantitative Biomechanics Imaging

      Massachusetts General Hospital Receives a 2019 NIH Grant for $340,916 for Quantitative Biomechanics Imaging. The principal investigator is Seok-Hyun Andy Yun. The program began in 2019 and ends in 2020. Below is a summary of the proposed work. TRD 1 The proposed research in TRD Project 1 is to develop novel optical coherence tomography (OCT)-based techniques and tools for measuring the mechanical properties and parameters as well as acoustic transduction in tissues. The focus on tissue biomechanics responds to the emerging opportunity to harness OCT's unique capabilities to obtain quantitative maps of tissue vibration, deformation, strain, and ...

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      Mentions: Seok-Hyun Yun Massachusetts General Hospital

    12. MGH Receives NIH Grant for: Percutaneous and Interstitial Imaging

      Explore Optical Coherence Tomography News Funding
      MGH Receives NIH Grant for: Percutaneous and Interstitial Imaging

      Massachusetts General Hospital Receives a 2019 NIH Grant for $317,085 for TRD23: Percutaneous and Interstitial Imaging. The principal investigator is Martin Villiger. The program began in 2019 and ends in 2020. Below is a summary of the proposed work. TRD 3 The overall goal of TRD 3 is to enable advanced OCT imaging, with high resolution and functional and dynamic contrast, inside the living body, through narrow diameter, rotational probes. Instruments and algorithms will be developed that overcome fundamental barriers, intrinsic to flexible, rotational fiber-optic probes, that have previously compromised image quality and prohibited the integration of functional and ...

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      Mentions: Massachusetts General Hospital Martin L. Villiger

    13. MGH Receives NIH Grant for TRD: Functional Imaging

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      MGH Receives NIH Grant for TRD: Functional Imaging

      Massachusetts General Hospital Receives a 2019 NIH Grant for $338,551 for TRD: Functional Imaging. The principal investigator is Benjamin Vakoc. The program began in 2019 and ends in 2021. Below is a summary of the proposed work. TRD 2 TRD project 2 will develop novel optical coherence tomography (OCT) technologies to address unmet needs in the functional imaging of tissue. Specific Aim #1 addresses the need for high-speed and high- resolution angiographic imaging systems for preclinical research. A new high-speed optical architecture for high-resolution optical coherence microscopy (OCM) will be constructed that is 100 times faster than existing OCM ...

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      Mentions: Massachusetts General Hospital Benjamin J. Vakoc

    14. MGH Receives NIH Grant for the Center for Biomedical OCT Research and Translation

      Explore Optical Coherence Tomography News Funding
      MGH Receives NIH Grant for the Center for Biomedical OCT Research and Translation

      Massachusetts General Hospital Receives a 2019 NIH Grant for $749,999 for the Center for Biomedical OCT Research and Translation. The principal investigator is Brett Bouma. The program began in 2011 and ends in 2021. Below is a summary of the proposed work. Overall the Center for Biomedical OCT Research and Translation seeks to push the technological frontier of optical coherence tomography instrumentation and methods in response to challenges in biology and medicine. Fundamental to our approach, CBORT thrives on an intimate, push-pull relationship between physicists/engineers and biological, pre-clinical and clinical scientists. The most direct impact o the Resource ...

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      Mentions: Brett E. Bouma Massachusetts General Hospital

    15. UIUC Receives NIH Grant for Integration of Raman Spectroscopy and OCT for In-vivo identification of Bacterial Otitis Media

      Explore Optical Coherence Tomography News Otolaryngology , Funding
      UIUC Receives NIH Grant for Integration of Raman Spectroscopy and OCT for In-vivo identification of Bacterial Otitis Media

      University of Illinois at Urbana Champaign Receives a 2019 NIH Grant for $648,154 for Integration of Raman Spectroscopy and Optical Coherence Tomography (RS-OCT) for In-vivo identification of Bacterial Otitis Media. The principal investigator is Stephen Boppart. The program began in 2019 and ends in 2023. Below is a summary of the proposed work. Otitis media (middle ear infection) is a highly prevalent disease, especially in young children. It has been documented that more than 75% of children will have at least one episode of otitis media (OM) by age 3, and many children will have recurrent or chronic OM ...

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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign
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    1. (4 articles) Massachusetts General Hospital
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  9. Picture Gallery

    ZEISS Marks Milestone for its New North America High Tech Site in Dublin, California Using Optical Coherence Tomography to Make Needle Biopsies Safer Identification of Retinal Biomarkers in Alzheimer’s Disease Using Optical Coherence Tomography: Recent Insights, Challenges, and Opportunities Senior Scientist on Topcon Milpitas California International Ocular Circulation Society Inaugural Meeting, August 10, 2019 Portland Oregon ZEISS Ophthalmic Digital Summit 2019 Bacterial Density and Biofilm Structure Determined by Optical Coherence Tomography Handheld spectrally encoded coherence tomography and reflectometry for motion-corrected ophthalmic optical coherence tomography and optical coherence tomography angiography Laser cleaning of paintings: in situ optimization of operative parameters through non-invasive assessment by optical coherence tomography (OCT), reflection FT-IR spectroscopy and laser induced fluorescence spectroscopy (LIF) Spatiotemporal Tracking of Brain-Tumor-Associated Myeloid Cells in Vivo through Optical Coherence Tomography with Plasmonic Labeling and Speckle Modulation Image contrast correction method in full-field optical coherence tomography Evaluation of posterior vitreous detachment using ultrasonography and optical coherence tomography

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    1. Imaging is more accurate, helps guide decisions and facilitates tailored therapy, especially in younger heart attack patients who more frequently have plaque erosion or non-atherosclerotic coronary artery disease.
      By Giulio Guagliumi
    2. We are very pleased with the outcomes of this study, which are the culmination of hard work by 47 physicians across 18 collaborating hospitals...What is further encouraging is that this study was undertaken without key technological improvements that have since been launched commercially. We anticipate that future studies using the Real-time Targeting laser marking feature and our newly launched artificial intelligence software, Intelligent Real-time Image Segmentation, will improve upon these already very positive results. Working together with our commercial partner, Merit Medical, and many of the leading hospitals in the United States, we are ecstatic that this technology continues to have an important and beneficial impact for patients.
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    3. We can’t use functional OCT/OCTA in the brain to look at neurovascular coupling at the cellular level because the brain is surrounded by the skull, and fine resolution isn’t possible...But we can use functional OCT/OCTA to examine the interactions between individual photoreceptors and their blood vessels in the retina, which is much more accessible in the eye.
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    4. With the NSTIN plot, the temporal quadrant of the retinal nerve fiber layer is displayed in the center of the B-scan. This portion of the disc is crucial for everyday visual function, and identification of abnormal thinning in this region is essential for managing glaucoma.
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    5. Conavi is delighted to receive approval for the clinical use of the Novasight Hybrid System in Canada and are thankful to the many researchers, clinicians, patients, employees and other stakeholders that made this milestone possible.
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    6. Being named a Fellow is a great honor, and I am in very illustrious company.
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    7. We are very excited and honored to partner with the team at Adachi. Adachi’s strong market presence in Otolaryngology, as well as their expertise in navigating Japanese regulatory and reimbursement pathways, will ensure a powerful launch of the TOMi Scope in the Japanese marketplace. We see this partnership as further validation of our technology and its potential to impact healthcare in a meaningful way. We look forward to a long and fruitful relationship with Adachi.
      By Ryan L. Shelton
    8. You can see right into the tooth,” said Dr. Daniel Fried, professor, University of California, San Francisco School of Dentistry. “The enamel looks almost like an ice cube...Many lesions in the mouth have been re-mineralized and...no longer need inter­vention,” said Fried. “Dentists have trouble telling the difference between active and arrested lesions; this new technology has the potential of differentiating them.
      By Daniel S. Fried
    9. OCT [already] has changed the practice of ophthalmol­ogy...It’s been very successful for retinal imaging...and it’s also very promising for dentistry...If the dentist doesn’t know if [a lesion] is active or arrested,” said Fried, “with OCT, you can actually see the lesion struc­ture, how deep it is and if it has a definitive surface zone suggesting that remineralization has occurred.
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    10. This is the largest meeting in the world for biomedical optics, and that's because of you!
      By Rox Anderson