1. Featured Articles

    1. Longitudinal deep-brain imaging in mouse using visible-light optical coherence tomography through chronic microprism cranial window

      Explore OSA | OSA Publishing Developmental Biology , Neurology
      Longitudinal deep-brain imaging in mouse using visible-light optical coherence tomography through chronic microprism cranial window

      We longitudinally imaged both the superficial and deep cortical microvascular networks in brains of healthy mice and in a mouse model of stroke in vivo using visible-light optical coherence tomography (vis-OCT). We surgically implanted a microprism in mouse brains sealed by a chronic cranial window. The microprism enabled vis-OCT to image the entire depth of the mouse cortex. Following microprism implantation, we imaged the mice for 28 days and found that that it took around 15 days for both the superficial and deep cortical microvessels to recover from the implantation surgery. After the brains recovered, we introduced ischemic strokes by ...

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      Mentions: Northwestern University Hao F. Zhang Roman V. Kuranov

    2. Postdoctoral Research Fellowships (Optical Coherence Tomography) at Massachusetts General Hosptial

      Explore Optical Coherence Tomography News Jobs & Studentships
      Postdoctoral Research Fellowships (Optical Coherence Tomography) at Massachusetts General Hosptial

      Employer Description Until recently, visualizing the architectural and cellular morphology of human tissue has required histopathological examination. Samples would be excised from the patient, processed, sectioned, stained and viewed under a microscope. In addition to being invasive, time consuming and costly, the static nature of conventional pathology prohibits the study of biological dynamics and function. The Tearney Laboratory at Massachusetts General Hospital has led the way in transforming the current diagnostic paradigm through the invention and translation of new noninvasive, high-resolution optical imaging modalities that enable disease diagnosis from living patients without excising tissues from the body. Led by Guillermo ...

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      Mentions: Guillermo J. Tearney Massachusetts General Hospital Harvard University

    3. Integrated optical system with photonic integrated circuit including coherent optical receiver and optical phased array

      Explore uspto.gov Patents
      Integrated optical system with photonic integrated circuit including coherent optical receiver and optical phased array

      An integrated optical system includes a frequency tunable optical source. A reference path is coupled to the frequency tunable source. The integrated optical system also includes a photonic integrated circuit (PIC) comprising a coherent optical receiver that is optically coupled to the reference path. An optical phased array is optically coupled to the frequency tunable source and is positioned to couple light to and from a sample. The integrated optical system is configured such that when the frequency tunable optical source is tuned in optical frequency, the coherent optical receiver produces electrical signals having optical information about the sample.

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      Mentions: Eric A. Swanson

    5. OCT and Ophthalmology in the Age of Artificial Intelligence, Tuesday Oct 8, 2019 1:00P EDT

      Explore Photonics.com
      OCT and Ophthalmology in the Age of Artificial Intelligence, Tuesday Oct 8, 2019 1:00P EDT

      This webinar will provide an executive overview for leaders in imaging and ophthalmology on how artificial intelligence (AI) is transforming the field of medical imaging. Presenter Nishant Mohan will provide a hands-on demonstration of how to develop a deep-learning AI system from scratch, giving attendees critical insight into how to use this powerful tool. Separating the hype from reality, Mohan will discuss essential concepts behind the revolutionizing power of AI. In addition, he will present critical factors in the ecosystem that is driving AI technology and major AI platforms. He will provide specific examples of the application of AI in ...

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      Mentions: Wasatch Photonics Nishant Mohan

    6. Electromagnetic analysis for optical coherence tomography based through silicon vias metrology

      Explore OSA | OSA Publishing NDE/NDT , Other Non-Medical
      Electromagnetic analysis for optical coherence tomography based through silicon vias metrology

      This paper reports on progress in the analysis of time-domain optical coherence tomography (OCT) applied to the dimensional metrology of through-silicon vias (TSVs), which are vertical interconnect accesses in silicon, enabling three-dimensional (3D) integration in microelectronics, and estimates the deviations from earlier, simpler models. The considered TSV structures are 1D trenches and circular holes etched into silicon with a large aspect ratio. As a prerequisite for a realistic modeling, we work with spectra obtained from reference interferograms measured at a planar substrate, which fully includes the dispersion of the OCT apparatus. Applying a rigorous modal approach, we estimate the differences ...

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    7. Postdoc Position at the University of Southern California

      Explore Optical Coherence Tomography News Ophthalmology , Jobs & Studentships
      Postdoc Position at the University of Southern California

      A postdoctoral researcher position is available immediately in the Department of Otolaryngology at the University of Southern California. The principal project will be to develop Optical Coherence Tomography (OCT) systems for functional and morphological imaging in the human ear. The utilization of OCT for imaging in the human ear is a growing field with a range of applications from basic science research to the diagnosis and monitoring of disease. The postdoctoral researcher will work within the lab of Brian Applegate, PhD , but in close collaboration with the group of John Oghalai, MD. They occupy adjacent lab space and are part ...

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      Mentions: University of Southern California Brian E. Applegate John S. Oghalai

    8. Specsavers Installs the 350th Topcon Maestro Fully Automated OCT

      Explore Optical Coherence Tomography News Ophthalmology , Other Business News
      Specsavers Installs the 350th Topcon Maestro Fully Automated OCT

      Leading OCT Technology Enables Specsavers Optometrists to Provide Unsurpassed Eye Care to Their Patients Topcon Medical Systems (TMS), of Oakland, NJ, USA, a leading provider of diagnostic equipment and software solutions for the eye care industry, and Specsavers, Australia’s #1 optometry practice network, are pleased to announce the installation of the 350th Topcon Maestro Fully Automated OCT/Fundus Camera into Specsavers retail locations across Australia and New Zealand. After careful consideration of several devices, Specsavers chose to incorporate the Maestro OCT into all its locations based on its ease of use, space-saving design, enhanced diagnostic tools and clinical accuracy ...

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      Mentions: Topcon Medical Systems Specsavers

    9. Measurement of Vibrating Tympanic Membrane in an In Vivo Mouse Model Using Doppler Optical Coherence Tomography

      Explore MDPI Open Access Journals Platform Otolaryngology
      Measurement of Vibrating Tympanic Membrane in an In Vivo Mouse Model Using Doppler Optical Coherence Tomography

      Optical coherence tomography (OCT) has a micro-resolution with a penetration depth of about 2 mm and field of view of about 10 mm. This makes OCT well suited for analyzing the anatomical and internal structural assessment of the middle ear. To study the vibratory motion of the tympanic membrane (TM) and its internal structure, we developed a phase-resolved Doppler OCT system using Kasai’s autocorrelation algorithm. Doppler optical coherence tomography is a powerful imaging tool which can offer the micro-vibratory measurement of the tympanic membrane and obtain the micrometer-resolved cross-sectional images of the sample in real-time. To observe the relative ...

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      Mentions: Jeehyun Kim Kyungpook National University Mansik Jeon

    10. Changes in viscoelastic properties of articular cartilage in early stage of osteoarthritis, as determined by optical coherence tomography-based strain rate tomography

      Explore BMC Musculoskeletal Disorders
      Changes in viscoelastic properties of articular cartilage in early stage of osteoarthritis, as determined by optical coherence tomography-based strain rate tomography

      Background Biomechanical changes in articular cartilage are associated with the onset of osteoarthritis. We developed an optical coherence tomography-based strain rate tomography method: stress relaxation optical coherence straingraphy (SR-OCSA). The purpose of this study was to establish an approach for measuring mechanical properties of articular cartilage using SR-OCSA, and to investigate the distribution of viscoelastic properties of articular cartilage in early osteoarthritis. Methods Anterior cruciate ligament transection surgery was performed on the left knees of 8–9-month-old New Zealand white rabbits. SR-OCSA was used to visualize and measure the viscoelastic properties of articular cartilage via attenuation coefficient of strain rate ...

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    11. Postdoc Opening in Coronary Artery, Intravascular OCT Computational Imaging at Case Western Reserve University

      Explore Optical Coherence Tomography News Cardiology , Jobs & Studentships
      Postdoc Opening in Coronary Artery, Intravascular OCT Computational Imaging at Case Western Reserve University

      We have a postdoctoral opportunity to advance new solutions in cardiovascular and ophthalmological biomedical imaging using machine and deep learning approaches. Projects include mass screening of disease, diagnosis/staging, treatment evaluation, and image guided therapies. A particular opportunity exists in coronary artery intravascular OCT, where we use biomechanical experiments, deep learning. and finite element modeling with the intention of creating software to help plan interventional treatments. Trainees will have an opportunity to join and learn from the wide ranging biomedical imaging community at Case Western Reserve University, which includes the Center of Computational Imaging and Personalized Diagnostics (CCIPD), the Case ...

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      Mentions: Case Western Reserve University David L. Wilson

    12. ZEISS Showcases New CIRRUS 6000 OCT System at the European Society of Retina Specialists 2019 Congress

      Explore Optical Coherence Tomography News Ophthalmology , Other Business News
      ZEISS Showcases New CIRRUS 6000 OCT System at the European Society of Retina Specialists 2019 Congress

      CIRRUS 6000 at EURETINA ZEISS Showcases New CIRRUS 6000 OCT System at the European Society of Retina Specialists 2019 Congress The ZEISS CIRRUS 6000, 100kHz OCT system promises to dramatically elevate the efficiency of eye care practices. ZEISS Medical Technology Segment expands its *CIRRUS ® — the most trusted Optical Coherence Tomography (OCT) with the launch of its new CIRRUS 6000, 100kHz ultra-fast OCT system that promises to dramatically elevate the efficiency of advanced care practices. CIRRUS 6000 is the latest addition to an already robust portfolio of OCT devices that are designed to meet the needs of all types and levels ...

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      Mentions: Carl Zeiss Meditec

    13. PhD Position at the Center for Medical Physics and Biomedical Engineering – Medical University of Vienna

      Explore Optical Coherence Tomography News Jobs & Studentships
      PhD Position at the Center for Medical Physics and Biomedical Engineering – Medical University of Vienna

      Position: PhD, Doctoral student in multimodal optical imaging Location: Center for Medical Physics and Biomedical Engineering – Medical University of Vienna Description: The Center for Medical Physics and Biomedical Engineering at the Medical University of Vienna has an immediate opening for a PhD position. The Center for Medical Physics and Biomedical Engineering is located in one of the largest European University hospitals (AKH Vienna) enabling multi-disciplinary innovative, vibrant science from bench to bedside. The research field focuses on the development, design, and realization as well as application of novel biomedical optical imaging technologies. The post will involve developing a novel imaging ...

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      Mentions: Medical University of Vienna

    14. Clinical use of intracoronary imaging. Part 2: acute coronary syndromes, ambiguous coronary angiography findings, and guiding interventional decision-making: an expert consensus document of the European Association of Percutaneous Cardiovascular Intervent

      Explore eurointervention.pcronline.com Cardiology
      Clinical use of intracoronary imaging. Part 2: acute coronary syndromes, ambiguous coronary angiography findings, and guiding interventional decision-making: an expert consensus document of the European Association of Percutaneous Cardiovascular Intervent

      This consensus document is the second of two reports summarizing the views of an expert panel organized by the European Association of Percutaneous Cardiovascular Interventions (EAPCI) on the clinical use of intracoronary imaging including intravascular ultrasound (IVUS), optical coherence tomography (OCT), and near infrared spectroscopy (NIRS)-IVUS. Beyond guidance of stent selection and optimization of deployment, invasive imaging facilitates angiographic interpretation and may guide treatment in acute coronary syndrome. Intravascular imaging can provide additional important diagnostic information when confronted with angiographically ambiguous lesions and allows assessment of plaque morphology enabling identification of vulnerability characteristics. This second document focuses on useful ...

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      Mentions: Imperial College London Columbia University Cardiovascular Research Foundation

    15. Assessment of simulated osteoporosis in alveolar bone using optical coherence tomography - Del‐Valle - - Journal of Biophotonics

      Explore Wiley Online Library Ophthalmology
      Assessment of simulated osteoporosis in alveolar bone using optical coherence tomography - Del‐Valle - - Journal of Biophotonics

      Osteoporosis is a skeletal disorder that compromises bone resistance and its diagnosis is usually performed using dual energy X‐ray absorptiometry. Thus, the search for efficient diagnostic methods that do not involve the emission of ionizing radiation is necessary. This study proposed to use the Optical Coherence Tomography (OCT) to evaluate osteoporosis in alveolar bone. Osteoporosis lesions is simulated in vitro in porcine bones, and imaging is performed by OCT and micro‐computed tomography (micro‐CT). A developed algorithm is proposed to calculate the optical attenuation coefficient ( μ t ), mean optical attenuation coefficient ( μ t ), integrated reflectivity ( Δ R ) and bone density ( BD ...

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    16. Cylite Announces Series B Funding Round led by Main Sequence Ventures

      Explore Optical Coherence Tomography News Funding , Other Business News
      Cylite Announces Series B Funding Round led by Main Sequence Ventures

      Cylite Pty Ltd, a developer of 3D imaging and measurement systems for Ophthalmology and Optometry announces the successful close of its Series B funding round led by leading Australian VC firm Main Sequence Ventures with participation from existing US and Australian investors. The new funding leverages previous funding, and grants from the Australian government, to build additional manufacturing capacity for Cylite’s Hyperparallel OCT (HP-OCT) platform as well as extend its sales and support networks in Europe and the US. The investment will also support further R&D to provide new diagnostic capabilities for improved outcomes in anterior segment cataract ...

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      Mentions: Cylite

    17. Optical probe using multimode optical waveguide and proximal processing

      Explore uspto.gov Patents , Probes
      Optical probe using multimode optical waveguide and proximal processing

      An optical probe includes an optical source that generates an optical beam that propagates from a proximal end to a distal end of an optical fiber that imparts a transformation of a spatial profile of the optical beam. An optical control device imparts a compensating spatial profile on the optical beam that at least partially compensates for the transformation of the spatial profile of the optical beam imparted by the optical fiber in response to a control signal from a signal processor. A distal optical source generates a calibration light that propagates through the one or more optical waveguides from ...

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      Mentions: Eric A. Swanson
    18. See all articles

  2. Recent Articles From Around The Web

    1. Diurnal Stability Of Peripapillary Vessel Density And Nerve Fiber Layer Thickness On Optical Coherence Tomography Angiography In Healthy, Ocular Hypertension And Glaucoma Eyes

      Explore Medical Journals Publisher Ophthalmology
      Diurnal Stability Of Peripapillary Vessel Density And Nerve Fiber Layer Thickness On Optical Coherence Tomography Angiography In Healthy, Ocular Hypertension And Glaucoma Eyes

      Purpose: By using optical coherence tomography angiography (OCTA), to evaluate diurnal changes of the following parameters: vessel density in the peripapillary area (PP-VD) and in the optic nerve head (ONH-VD); thickness of retinal nerve fibre layer (RNFL) and ganglion cell complex (GCC). Methods: All prospectively enrolled participants were imaged on the same day at 8 am and 7 pm by means of the XR Avanti device with AngioVue and AngioAnalytics software (Optovue Inc., Fremont, CA, USA). Only eyes with correct automatic segmentation and good-quality images (scan quality > 7/10) were included. Results: Forty-six eyes from 28 patients with glaucoma, 53 ...

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    2. The impact of artificial intelligence in the diagnosis and management of glaucoma

      Explore Nature Publishing Group Ophthalmology
      The impact of artificial intelligence in the diagnosis and management of glaucoma

      eep learning (DL) is a subset of artificial intelligence (AI), which uses multilayer neural networks modelled after the mammalian visual cortex capable of synthesizing images in ways that will transform the field of glaucoma. Autonomous DL algorithms are capable of maximizing information embedded in digital fundus photographs and ocular coherence tomographs to outperform ophthalmologists in disease detection. Other unsupervised algorithms such as principal component analysis (axis learning) and archetypal analysis (corner learning) facilitate visual field interpretation and show great promise to detect functional glaucoma progression and differentiate it from non-glaucomatous changes when compared with conventional software packages. Forecasting tools such ...

      Read Full Article

    3. VIS-OCT offers sight line

      Explore Photonics.com Microscopy , Ophthalmology
      VIS-OCT offers sight line

      The benefits of optical coherence tomography (OCT) have long been known as an imaging tool in ophthalmology, enabling the examination of the eye at microscopic resolution. But what may not be widely appreciated is that the use of visible light sources can improve upon the results of this well-developed technique in the detection and understanding of various eye-related diseases such as macular degeneration and glaucoma. While most commercial OCT and OCTA (angiography) systems use NIR light for economic and technical reasons, broadband visible light sources have expanded from 400 to 2000 nm or more. This has enabled the imaging of ...

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    4. Avinger Announces Full Commercial Launch of Pantheris SV

      Explore Optical Coherence Tomography News Cardiology , Other Business News
      Avinger Announces Full Commercial Launch of Pantheris SV

      Avinger, Inc. (NASDAQ: AVGR ), a commercial-stage medical device company marketing the first and only intravascular image-guided, catheter-based system for diagnosis and treatment of Peripheral Artery Disease (PAD), today announced the full commercial launch of the Pantheris SV (small vessel) image-guided atherectomy system in the U.S. All current and prospective Lumivascular accounts are now eligible to order the Pantheris SV device. Avinger launched Pantheris SV at select Avinger sites in late July in order to demonstrate the product's ease of use and efficiency across a variety of user approaches and vascular conditions in a real-world clinical setting, as well ...

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      Mentions: Avinger

    5. Postdoctoral Research Fellowships (In Vivo Microscopy) At Massachusetts General Hospital

      Explore Optical Coherence Tomography News Jobs & Studentships
      Postdoctoral Research Fellowships (In Vivo Microscopy) At Massachusetts General Hospital

      Employer Description Until recently, visualizing the architectural and cellular morphology of human tissue has required histopathological examination. Samples would be excised from the patient, processed, sectioned, stained and viewed under a microscope. In addition to being invasive, time consuming and costly, the static nature of conventional pathology prohibits the study of biological dynamics and function. The Tearney Laboratory at Massachusetts General Hospital has led the way in transforming the current diagnostic paradigm through the invention and translation of new noninvasive, high-resolution optical imaging modalities that enable disease diagnosis from living patients without excising tissues from the body. Led by Guillermo ...

      Read Full Article
      Mentions: Guillermo J. Tearney Massachusetts General Hospital Harvard University

    6. Circumpapillary and macular vessel density assessment by optical coherence tomography angiography in eyes with temporal hemianopia from chiasmal compression. Correlation with retinal neural and visual field loss

      Explore Nature Publishing Group Ophthalmology
      Circumpapillary and macular vessel density assessment by optical coherence tomography angiography in eyes with temporal hemianopia from chiasmal compression. Correlation with retinal neural and visual field loss

      Aims To compare the circumpapillary and macular vessel density (cpVD/mVD) of eyes with temporal visual field (VF) defect and band atrophy (BA) of the optic nerve and normal controls using OCTA and to verify the association of VD parameters with circumpapillary retinal nerve fibre layer (cpRNFL) thickness, macular ganglion cell complex (mGCC) thickness and VF loss. Methods Thirty-three eyes of 26 patients with BA and 42 eyes of 22 age-matched normal controls underwent OCT + OCTA scanning. cpVD and cpRNFL were expressed as average and sector measurements. mVD and mGCC were calculated as averages and in quadrants and hemiretinas. VF ...

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      Mentions: University of São Paulo

    7. Miniaturizing medical imaging, sensing technology

      Explore PhysOrg.com
      Miniaturizing medical imaging, sensing technology

      Scientists in Christine Hendon's and Michal Lipson's research groups at Columbia University, New York, have used a microchip to map the back of the eye for disease diagnosis. The interference technology, like bat sonar but using light instead of sound waves , used in the microchip has been around for a little while. This is the first time that technical obstacles have been overcome to fabricate a miniature device able to capture high quality images. Ophthalmologists' current optical coherence tomography (OCT) devices and surveyors' light detection and ranging (LIDAR) machines are bulky and expensive. There is a push for ...

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      Mentions: Columbia University Christine P. Hendon

    8. On-chip tunable photonic delay line

      Explore aip.scitation.org
      On-chip tunable photonic delay line

      An on-chip tunable photonic delay line is a key building block for applications including sensing, imaging, and optical communication. However, achieving long and tunable delay lines within a small footprint remains challenging. Here, we demonstrate an on-chip tunable photonic delay line using ultralow loss high confinement Si 3 N 4 waveguides with integrated microheaters. As an example of potential application, we embed a 0.4 m delay line within an optical coherence tomography (OCT) system. We show that the delay line can extend the OCT imaging range by 0.6 mm while maintaining a high signal to noise ratio. Our ...

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      Mentions: Columbia University Christine P. Hendon

    9. Canon Xephilio OCT-A1 Optical Coherence Tomography Device Receives FDA 510(k) Clearance

      Explore Optical Coherence Tomography News Ophthalmology , Other Business News
      Canon Xephilio OCT-A1 Optical Coherence Tomography Device Receives FDA 510(k) Clearance

      Expanding the company's lineup of eye-care product offerings, Canon U.S.A. , Inc., a leader in digital imaging solutions, is pleased to announce the new intuitive, user-friendly Xephilio OCT-A1 Optical Coherence Tomography device from Canon Inc. This device features automated acquisition functionality, which makes it easy to use, allowing healthcare professionals to obtain high-quality reproducible scans and images. The Xephilio OCT-A1 Optical Coherence Tomography device has received FDA 510(k) clearance for sale in the United States of America 1. The Xephilio OCT-A1 Optical Coherence Tomography device, together with the required RX Capture software, computer and LCD monitor (collectively ...

      Read Full Article
      Mentions: Canon Medical Systems

    10. Subintimal Versus Intraplaque Recanalization of Coronary Chronic Total Occlusions: Mid-Term Angiographic and OCT Findings From the ISAR-OCT-CTO Registry

      Explore ScienceDirect Cardiology
      Subintimal Versus Intraplaque Recanalization of Coronary Chronic Total Occlusions: Mid-Term Angiographic and OCT Findings From the ISAR-OCT-CTO Registry

      Objectives The aim of this study was to compare angiographic and optical coherence tomography findings following subintimal as opposed to intraplaque recanalization of chronic total occlusions (CTOs). Background There is ongoing controversy regarding outcomes of intraplaque versus subintimal CTO recanalization. Methods Consecutive patients undergoing angiography and intravascular optical coherence tomography following CTO recanalization were included in the ISAR-OCT-CTO (Intracoronary Stenting and Angiographic Results - Optical Coherence Tomography for Chronic Total Occlusions) registry. The study endpoints were percent diameter stenosis and late lumen loss as well as rate of uncovered and malapposed struts. Independent correlates of uncovered and malapposed struts were assessed ...

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      Mentions: Michael Joner Technical University of Munich

    11. Review of methods and applications of attenuation coefficient measurements with optical coherence tomography

      Explore SPIE Digital Library
      Review of methods and applications of attenuation coefficient measurements with optical coherence tomography

      The optical attenuation coefficient (AC), an important tissue parameter that measures how quickly incident light is attenuated when passing through a medium, has been shown to enable quantitative analysis of tissue properties from optical coherence tomography (OCT) signals. Successful extraction of this parameter would facilitate tissue differentiation and enhance the diagnostic value of OCT. In this review, we discuss the physical and mathematical basis of AC extraction from OCT data, including current approaches used in modeling light scattering in tissue and in AC estimation. We also report on demonstrated clinical applications of the AC, such as for atherosclerotic tissue characterization ...

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      Mentions: Vanderbilt University Audrey K. Bowden

    12. Techniques in Optical Coherence and Resonance for Sensing (Thesis)

      Explore eScholarship Student Theses
      Techniques in Optical Coherence and Resonance for Sensing (Thesis)

      Optical sensors are ubiquitous for their precision and non-contact acquisition, and have enjoyed widespread use in applications such as biosensing, environmental monitoring, and security. Despite their sensitivity, many of these sensors rely on costly laboratory instrumentation, and are not adaptable to the ever-growing volume of consumer detectors and optics that are readily available, making their application limited to benchtop analytics. This work leverages plasmonic resonances and optical coherence phenomena to make modifications upon traditional sensing formats that improve their sensitivity when deployed in off-the-shelf optical systems. In particular, we demonstrate that label-free plasmonic sensors can be combined with electrochemical impedance ...

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    13. Recent progress in optical probing and manipulation of tissue: introduction

      Explore OSA | OSA Publishing
      Recent progress in optical probing and manipulation of tissue: introduction

      This feature issue of Biomedical Optics Express represents a cross-section of the most recent work in tissue optics, including exciting developments in tissue optical clearing, deep tissue imaging, optical elastography, nanophotonics in tissue, and therapeutic applications of light, amongst others. A collection of 33 papers provides a comprehensive overview of current research in tissue optics, much of it inspired and informed by the pioneering work of Prof. Valery Tuchin. The issue contains three invited manuscripts and several mini-reviews that we hope will benefit researchers in this exciting area.

      Read Full Article
      Mentions: Kirill V. Larin University of Houston David D. Sampson

    14. Elimination of Artifacts Caused by the Nonidentity of Parallel Signal-Reception Channels in Spectral Domain Optical Coherence Tomography

      Explore Home - Springer
      Elimination of Artifacts Caused by the Nonidentity of Parallel Signal-Reception Channels in Spectral Domain Optical Coherence Tomography

      We study the causes of artifact appearance in the images obtained by the method of spectral domain optical coherence tomography with parallel reception of the optical-spectrum components, which are manifested in repetition and overlay of the structural elements of the images of the studied medium with a shift in depth. It is shown that nonidentity of the transfer characteristics of the channels of the multichannel photoreceiving elements is one of the sources of such artifacts. A numerical method for eliminating such artifacts is proposed and experimentally verified. This method is based on using the models whose parameters are estimated by ...

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      Mentions: Institute of Applied Physics Grigory V. Gelikonov Valentin M. Gelikonov

    15. Changes in Amblyopia Using Optical Coherence Tomography

      Explore Home - ClinicalTrials.gov Ophthalmology , Clinical Trials
      Changes in Amblyopia Using Optical Coherence Tomography

      There have been multiple trials to investigate the morphological changes in the macula and retinal nerve fiber layer of amblyopic eyes, due to the different published results and the lack of evident association between these changes and the patients' parameters. So, we perform this study to compare the variations in macular parameters (central thickness, average thickness, macular volume) and peripapillary thickness in different cases of amblyopic eyes versus the normal fellow eyes using spectral-domain optical coherence tomography . In addition, to estimate the relationship of optical coherence tomography variations with different defined patients' parameters (age, sex, best corrected visual acuity, spherical ...

      Read Full Article
      16. See all articles
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  6. Organizations in the News

    1. (2 articles) Institute of Applied Physics
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    1. (2 articles) Guillermo J. Tearney
    2. (2 articles) Grigory V. Gelikonov
    3. (2 articles) Valentin M. Gelikonov
    4. (2 articles) Christine P. Hendon
    5. (2 articles) Pavel A. Shilyagin
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    10. (1 articles) Pearse A. Keane
    11. (1 articles) Akitaka Tsujikawa
    12. (1 articles) Zhongping Chen
    13. (1 articles) Steven T. Bailey
    14. (1 articles) Matthew Brenner
    15. (1 articles) Yali Jia

  8. OCT Companies in the News

    1. (2 articles) Canon Medical Systems
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    3. (1 articles) Wasatch Photonics
    4. (1 articles) Opticent Health
    5. (1 articles) Avinger

  9. Picture Gallery

    Longitudinal deep-brain imaging in mouse using visible-light optical coherence tomography through chronic microprism cranial window Postdoctoral Research Fellowships (Optical Coherence Tomography) at Massachusetts General Hosptial Integrated optical system with photonic integrated circuit including coherent optical receiver and optical phased array Optoretinography: optical measurements of human cone and rod photoreceptor responses to light OCT and Ophthalmology in the Age of Artificial Intelligence, Tuesday Oct 8, 2019 1:00P EDT Electromagnetic analysis for optical coherence tomography based through silicon vias metrology Postdoc Position at the University of Southern California Specsavers Installs the 350th Topcon Maestro Fully Automated OCT Measurement of Vibrating Tympanic Membrane in an In Vivo Mouse Model Using Doppler Optical Coherence Tomography Changes in viscoelastic properties of articular cartilage in early stage of osteoarthritis, as determined by optical coherence tomography-based strain rate tomography Postdoc Opening in Coronary Artery, Intravascular OCT Computational Imaging at Case Western Reserve University ZEISS Showcases New CIRRUS 6000 OCT System at the European Society of Retina Specialists 2019 Congress

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    1. An historic issue with OCT is that the depth resolution is typically several times better than the lateral resolution...If the layers of imaged tissues happen to be horizontal, then they're well defined in the scan. But to extend the full power of OCT for live imaging of tissues throughout the body, a method for overcoming the tradeoff between lateral resolution and depth of imaging was needed.
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    2. With advances in microscopy techniques such as ours, we hope to change the way we detect, visualize and monitor diseases that will lead to better diagnosis, treatments and outcomes.
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      By Giulio Guagliumi
    6. We are very pleased with the outcomes of this study, which are the culmination of hard work by 47 physicians across 18 collaborating hospitals...What is further encouraging is that this study was undertaken without key technological improvements that have since been launched commercially. We anticipate that future studies using the Real-time Targeting laser marking feature and our newly launched artificial intelligence software, Intelligent Real-time Image Segmentation, will improve upon these already very positive results. Working together with our commercial partner, Merit Medical, and many of the leading hospitals in the United States, we are ecstatic that this technology continues to have an important and beneficial impact for patients.
      By Eman Namati
    7. We can’t use functional OCT/OCTA in the brain to look at neurovascular coupling at the cellular level because the brain is surrounded by the skull, and fine resolution isn’t possible...But we can use functional OCT/OCTA to examine the interactions between individual photoreceptors and their blood vessels in the retina, which is much more accessible in the eye.
      By Xincheng Yao
    8. With the NSTIN plot, the temporal quadrant of the retinal nerve fiber layer is displayed in the center of the B-scan. This portion of the disc is crucial for everyday visual function, and identification of abnormal thinning in this region is essential for managing glaucoma.
      By Donald C. Hood
    9. Conavi is delighted to receive approval for the clinical use of the Novasight Hybrid System in Canada and are thankful to the many researchers, clinicians, patients, employees and other stakeholders that made this milestone possible.
      By Brian K. Courtney
    10. Being named a Fellow is a great honor, and I am in very illustrious company.
      By Audrey K. Bowden