1. Feature Of The Week

    Laser transmission welding as a contactless and locally limited joining technique is well-established in different production areas. It is used in a variety of demanding applications like for example parts which require a particle-free joining process. Sensitive parts demand a joining technique which does not affect the inner components. The welding process itself faces higher requirements concerning for example tightness of the weld joint or cleanliness of the produced part (no material must impurify the part during the process).

    During the laser transmission welding process the laser radiation is locally focused on an absorbing surface. The joining is performed between a transmissive part (regarding the process laser wavelength) and an absorbing part. After solidification the weld seam is created at the intersection of both parts within the material. The weld seam is hermetically enclosed within the material and cannot be visually inspected.

    A very narrow process parameter window during the laser process or process deviations have led to an increase on the requirements for the laser transmission welding process and on monitoring devices. A qualitative feedback for process adaptation is not given by today´s state of the art measurement systems. Pyrometers detect the process emission but return no tomographical information. Quality assurance of the fabricated product is done via destructive testing resulting in production of scrap parts.

    Inline integrated optical measurement systems capable of providing non-invasive tomographical images of the transparent material, the weld seam and its surrounding areas with micron resolution would improve the overall process by providing more detailed information about the actual forming process. Hereby obtained measurement data enable qualitative feedback into the system to adapt process parameters to obtain a more robust laser transmission welding process. Non-destructive testing during the laser welding process would reduce the process cost as well.

    Within the European-funded research project Manunet “Weldable” an inline monitoring device based on Fourier-domain optical coherence tomography was developed at the Fraunhofer IPT. This device, after adaptation to the laser transmission welding process is optically integrated into the existing laser machine. Pre-process analysis of the work piece can as easily be performed as well as post-process quality assurance inspection. The main target lies within the inline process control destined to extract tomographical geometrical measurement data from the weld seam forming process. Hereby process feedback is given to adapt prior set laser parameters as well as high resolution images are made available for quality inspection. In-process obtained data make obsolete the need for further testing and reduce the handling of the product. Usage of this non-destructive and non-invasive technology makes offline destructive testing of produced parts unnecessary as any defects occurring during the process can be identified and its information feedback for laser process adaptation, delivering hereby a reliable weld process and a safe product.

    For more information see recent Article. Courtesy Robert Schmitt from RWTH Aachen University and Philippe Ackermann from Fraunhofer-Institut für Produktionstechnologie. To share this article click Here.

  2. Featured Articles

    1. Viewing a Weld Seam in 360°: New Scan Solution Utilizes OCT Technology to Coaxially Track and Inspect Seams

      Explore Optical Coherence Tomography News NDE/NDT
      Viewing a Weld Seam in 360°: New Scan Solution Utilizes OCT Technology to Coaxially Track and Inspect Seams

      At the Laser World of Photonics tradeshow in Munich, Germany, Blackbird Robotersysteme GmbH (acknowledged remote welding expert and SCANLAB GmbH associate company) will present an entirely new scan solution prototype with integrated distance sensor. Based on optical coherence tomography (OCT), the system detects and measures 3D laser weld seam topographies in high resolution. This is particularly advantageous for industrial system integrators and users looking to secure process safety and comprehensive quality management without a separate monitoring solution. In healthcare OCT has proven itself as an examination technique for opththamology, skin analysis, cancer diagnosis and more. For patients, this optical measurement ...

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      Mentions: Blackbird Robotersysteme GmbH SCANLAB GmbH

    2. Highly phase-stable 200 kHz swept-source optical coherence tomography based on KTN electro-optic deflector

      Explore OSA | OSA Publishing Tunable Sources
      Highly phase-stable 200 kHz swept-source optical coherence tomography based on KTN electro-optic deflector

      The rapid advance in swept-source optical coherence tomography (SS-OCT) technology has enabled exciting new applications in elastography, angiography, and vibrometry, where both high temporal resolution and phase stability are highly sought-after. In this paper, we present a 200 kHz SS-OCT system centered at 1321 nm by using an electro-optically tuned swept source. The proposed system’s performance was fully characterized, and it possesses superior phase stability (0.0012% scanning variability and <1 ns timing jitter) that is promising for many phase-sensitive imaging applications. Biological experiments were demonstrated within ex vivo human tracheobronchial ciliated epithelium where both the ciliary motion and ...

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      Mentions: Columbia University Christine Hendon

    3. Two Engineering Openings at Startup Company Opticent Health

      Explore Optical Coherence Tomography News Jobs & Studentships
      Two Engineering Openings at Startup Company Opticent Health

      Opticent, Inc. (Opticent Health – www.opticenthealth.com) is a start-up company commercializing an in-house developed patent portfolio related to visible-light optical coherence tomography (OCT) targeting the ophthalmic market. Opticent Health’s core technologies were developed at Northwestern University. Since its founding, Opticent Health has experienced rapid market adoption of its OCT instruments and rapid commercial expansion. Opticent Health is located in Evanston IL, part of the greater Chicago metropolitan area. The company’s management team, with guidance from its prominent advisory board, is expanding its engineering staff and seeks highly qualified personnel for the following two positions: 1. Ph.D ...

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      Mentions: Northwestern University Hao F. Zhang Opticent Health

    4. Complex decorrelation averaging in optical coherence tomography: a way to reduce the effect of multiple scattering and improve image contrast in a dynamic scattering medium

      Explore OSA | OSA Publishing
      Complex decorrelation averaging in optical coherence tomography: a way to reduce the effect of multiple scattering and improve image contrast in a dynamic scattering medium

      We demonstrate that complex decorrelation averaging can reduce the effect of multiple scattering and improve optical coherence tomography (OCT) imaging contrast. Complex decorrelation averaging calculates the product of an A-scan and the complex conjugate of a subsequent A-scan. The resultant signal is the product of the amplitudes and the phase difference. All these resulting complex signals at a particular location are then averaged. We take advantage of the fact that complex averaging, in contrast to conventional magnitude averaging, is sensitive to phase decorrelation. Sample motion that increases signal phase variance results in lower signal magnitude after complex averaging. Such motion ...

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      Mentions: Andrew M. Rollins Case Western Reserve University Lars Thrane

    5. Michelson Diagnostics Secures CPT codes for Optical Coherence Tomography Imaging of Skin

      Explore Optical Coherence Tomography News Dermatology , Other Business News
      Michelson Diagnostics Secures CPT codes for Optical Coherence Tomography Imaging of Skin

      Michelson Diagnostics announces that the American Medical Association (AMA) CPT Editorial Panel recently approved two new Category III CPT codes for Optical Coherence Tomography (OCT) imaging of skin. Code 0470T is for OCT microstructural and morphological imaging of skin, image acquisition, interpretation and report for a first lesion; code 0471T is the same for each additional lesion. The new Category III codes, which are for emerging technologies, services, and procedures, are effective July 1, 2017. Michelson Diagnostics pursued approval of this code at the AMA CPT Panel meeting in October 2017, receiving support from the American Academy of Dermatology. “Obtaining ...

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      Mentions: Michelson Diagnostics Jon Holmes FDA

    6. Murine chronic lymph node window for longitudinal intravital lymph node imaging

      Explore Nature Publishing Group
      Murine chronic lymph node window for longitudinal intravital lymph node imaging

      Chronic imaging windows in mice have been developed to allow intravital microscopy of many different organs and have proven to be of paramount importance in advancing our knowledge of normal and disease processes. A model system that allows long-term intravital imaging of lymph nodes would facilitate the study of cell behavior in lymph nodes during the generation of immune responses in a variety of disease settings and during the formation of metastatic lesions in cancer-bearing mice. We describe a chronic lymph node window (CLNW) surgical preparation that allows intravital imaging of the inguinal lymph node in mice. The CLNW is ...

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      Mentions: Massachusetts General Hospital Harvard University Sungkyunkwan University

    7. Assessment of the radiofrequency ablation dynamics of esophageal tissue with optical coherence tomography

      Explore SPIE | Journal Gastroenterology
      Assessment of the radiofrequency ablation dynamics of esophageal tissue with optical coherence tomography

      Radiofrequency ablation (RFA) is widely used for the eradication of dysplasia and the treatment of early stage esophageal carcinoma in patients with Barrett’s esophagus (BE). However, there are several factors, such as variation of BE epithelium (EP) thickness among individual patients and varying RFA catheter-tissue contact, which may compromise RFA efficacy. We used a high-speed optical coherence tomography (OCT) system to identify and monitor changes in the esophageal tissue architecture from RFA. Two different OCT imaging/RFA application protocols were performed using an ex vivo swine esophagus model: (1) post-RFA volumetric OCT imaging for quantitative analysis of the coagulum ...

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      Mentions: Massachusetts Institute of Technology James G. Fujimoto Harvard University

    8. Optical coherence tomography angiography of retinal vascular occlusions produced by imaging-guided laser photocoagulation

      Explore OSA | OSA Publishing
      Optical coherence tomography angiography of retinal vascular occlusions produced by imaging-guided laser photocoagulation

      Retinal vascular occlusive diseases represent a major form of vision loss worldwide. Rodent models of these diseases have traditionally relied upon a slit-lamp biomicroscope to help visualize the fundus and subsequently aid delivery of high-power laser shots to a target vessel. Here we describe a multimodal imaging system that can produce, image, and monitor retinal vascular occlusions in rodents. The system combines a spectral-domain optical coherence tomography system for cross-sectional structural imaging and three-dimensional angiography, and a fluorescence scanning laser ophthalmoscope for Rose Bengal monitoring and high-power laser delivery to a target vessel. This multimodal system facilitates the precise production ...

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      Mentions: Northwestern University Hao F. Zhang

    10. Assessment of acquired mucociliary clearance defects using micro-optical coherence tomography

      Explore Wiley Online Library
      Assessment of acquired mucociliary clearance defects using micro-optical coherence tomography

      Background Dehydration of airway surface liquid (ASL) disrupts normal mucociliary clearance (MCC) in sinonasal epithelium, which may lead to chronic rhinosinusitis (CRS). Abnormal chloride (Cl − ) transport is one such mechanism that contributes to this disorder and can be acquired secondary to environmental perturbations, such as hypoxia at the tissue surface. The objective of this study was to assess the technological feasibility of the novel micro-optical coherence tomography (μOCT) imaging technique for investigating acquired MCC defects in cultured human sinonasal epithelial (HSNE) cells. Methods Primary HSNE cell cultures were subjected to a 1% oxygen environment for 12 hours to induce acquired ...

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      Mentions: Guillermo J. Tearney Massachusetts General Hospital Harvard University

    11. Can OCT Angiography Be Made a Quantitative Blood Measurement Tool?

      Explore MDPI Open Access Journals Platform
      Can OCT Angiography Be Made a Quantitative Blood Measurement Tool?

      Optical Coherence Tomography Angiography (OCTA) refers to a powerful class of OCT scanning protocols and algorithms that selectively enhance the imaging of blood vessel lumens, based mainly on the motion and scattering of red blood cells (RBCs). Though OCTA is widely used in clinical and basic science applications for visualization of perfused blood vessels, OCTA is still primarily a qualitative tool. However, more quantitative hemodynamic information would better delineate disease mechanisms, and potentially improve the sensitivity for detecting early stages of disease. Here, we take a broader view of OCTA in the context of microvascular hemodynamics and light scattering. Paying ...

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      Mentions: Vivek J. Srinivasan UC Davis

    12. Tunable laser array system

      Explore uspto.gov Patents , Tunable Sources
      Tunable laser array system

      A system for swept source optical coherence tomography, the system including a light source emitting multiplexed wavelength-swept radiation over a total wavelength range, the light source including N wavelength-swept vertical cavity lasers (VCL) emitting N tunable VCL outputs having N wavelength trajectories, a combiner for combining the N tunable VCL optical outputs into a common optical path to create the multiplexed wavelength-swept radiation, a splitter for splitting the multiplexed wavelength-swept radiation to a sample and a reference path, an optical detector for detecting an interference signal created by an optical interference between a reflection from the sample and light traversing ...

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      Mentions: Thorlabs Alex E. Cable Benjamin M. Potsaid

    13. Automatic classification of atherosclerotic tissue in intravascular optical coherence tomography images

      Explore OSA | OSA Publishing Cardiology
      Automatic classification of atherosclerotic tissue in intravascular optical coherence tomography images

      Intravascular optical coherence tomography (IVOCT) has been successfully utilized for in vivo diagnostics of coronary plaques. However, classification of atherosclerotic tissues is mainly performed manually by experienced experts, which is time-consuming and subjective. To overcome these limitations, an automatic method of segmentation and classification of IVOCT images is developed in this paper. The method is capable of detecting the plaque contour between the fibrous tissues and other components. Subsequently, the method classifies the tissues based on their texture features described by Fourier transform and discrete wavelet transform. The experimental results of 103 images show that an overall classification accuracy of ...

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    14. Optical coherence microscopy as a novel, non-invasive method for the 4D live imaging of early mammalian embryos

      Explore Nature Publishing Group Developmental Biology , Microscopy
      Optical coherence microscopy as a novel, non-invasive method for the 4D live imaging of early mammalian embryos

      Imaging of living cells based on traditional fluorescence and confocal laser scanning microscopy has delivered an enormous amount of information critical for understanding biological processes in single cells. However, the requirement for a high numerical aperture and fluorescent markers still limits researchers’ ability to visualize the cellular architecture without causing short- and long-term photodamage. Optical coherence microscopy (OCM) is a promising alternative that circumvents the technical limitations of fluorescence imaging techniques and provides unique access to fundamental aspects of early embryonic development, without the requirement for sample pre-processing or labeling. In the present paper, we utilized the internal motion of ...

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      Mentions: Maciej Wojtkowski Nicolaus Copernicus University Maciej Szkulmowski

    15. Compact Imaging Teams with SRI International for Dynamic Biometrics Development under IARPA Odin Program

      Explore Optical Coherence Tomography News Other Non-Medical , Funding
      Compact Imaging Teams with SRI International for Dynamic Biometrics Development under IARPA Odin Program

      Compact Imaging, Inc. (CI) today announced that SRI International has selected CI’s non-invasive depth scanning sensor, MRO™, as a critical component in the development of “dynamic biometrics” for improved detection of attempts to evade or deceive biometric security systems, such as fingerprint scanners. The development is being performed under a multi-year contract awarded to SRI as part of IARPA’s (Intelligence Advanced Research Projects Activity, National Intelligence Directorate) Odin Program. The goal of the Odin Program is to develop advanced technologies to detect “presentation attacks,” as attempts to deceive biometric security systems are often called. Conventional biometrics, such as ...

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      Mentions: Don Bogue Compact Imaging, Inc

    16. 16  MHz wavelength-swept and wavelength-stepped laser architectures based on stretched-pulse active mode locking with a single continuously chirped fiber Bragg grating

      Explore OSA | OSA Publishing Tunable Sources
      16  MHz wavelength-swept and wavelength-stepped laser architectures based on stretched-pulse active mode locking with a single continuously chirped fiber Bragg grating

      We demonstrate a novel high-speed and broadband laser architecture based on stretched pulse active mode locking that provides a wavelength-swept and wavelength-stepped output. The laser utilizes a single intracavity 8.3 meter chirped fiber Bragg grating to generate positive and negative dispersion, and can be operated with or without an intracavity fixed Fabry–Perot etalon to generate wavelength-swept and wavelength-stepped (frequency comb) outputs, respectively. Using a four-path delay line at the output, we achieved 16.3 MHz repetition rates and a 62 nm lasing bandwidth centered at 1550 nm. Single-sided double-pass coherence lengths of 1.25 mm for the wavelength-swept ...

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      Mentions: Massachusetts Institute of Technology Massachusetts General Hospital Harvard University
    17. See all articles

  3. Recent Articles From Around The Web

    1. Imaging the event-prone coronary artery plaque

      Explore Home - Springer Cardiology
      Imaging the event-prone coronary artery plaque

      Acute coronary events, the dreaded manifestation of coronary atherosclerosis, remain one of the main contributors to mortality and disability in the developed world. The majority of those events are associated with atherosclerotic plaques-related thrombus formation following an acute disruption, that being rupture or erosion, of an event-prone lesion. These historically termed vulnerable plaques have been the target of numerous benchtop and clinical research endeavors, yet to date without solid results that would allow for early identification and potential treatment. Technological leaps in cardiovascular imaging have provided novel insights into the formation and role of the event-prone plaques. From intracoronary optical ...

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    2. K-distribution three-dimensional mapping of biological tissues in optical coherence tomography

      Explore Wiley Online Library
      K-distribution three-dimensional mapping of biological tissues in optical coherence tomography

      Probability density function (PDF) analysis with K-distribution model of optical coherence tomography (OCT) intensity signals has previously yielded a good representation of the average number of scatterers in a coherence volume for microspheres-in-water systems, and has shown initial promise for biological tissue characterization. In this work, we extend these previous findings, based on single point M-mode or 2D slice analysis, to full 3D imaging maps of the shape parameter α of the K-distribution PDF. After selecting a suitably-sized 3D evaluation window, and verifying methodology in phantoms the resultant parametric α images obtained in different animal tissues (rat liver and brain) show new ...

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      Mentions: University of Toronto I. Alex Vitkin

    3. Macular findings in Spectral Domain Optical Coherence Tomography and OCT Angiography in a patient with Kearns–Sayre syndrome

      Explore journalretinavitreous.biomedcentral.com Ophthalmology
      Macular findings in Spectral Domain Optical Coherence Tomography and OCT Angiography in a patient with Kearns–Sayre syndrome

      Background To report the clinical, electrophysiological and the anatomical findings in a patient with Kearns–Sayre syndrome (KSS). Case Presentation We present the case of a 55-year-old female with KSS, who developed systemic features and ocular manifestations as ophthalmoplegia and retinal dysfunction, that were corroborated by electrophysiological test and High Definition Spectral Domain Optical Coherence Tomography (HD SD OCT) and OCT-Angiography (OCT-A). Conclusion We report a patient with KSS, accompanied by some alterations of the RPE and photoreceptors observed in the external HD SD OCT and OCT-A. In the best of our knowledge, this is the first report in the ...

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    4. Current clinical applications of coronary optical coherence tomography

      Explore Home - Springer Cardiology
      Current clinical applications of coronary optical coherence tomography

      Optical coherence tomography (OCT) is an intra-coronary diagnostic technique that provides detailed imagings of blood vessels in the current cardiac catheterization laboratory. The higher resolution of OCT often provides superior delineation of each structure compared with intravascular ultrasound (IVUS), and it can reliably visualize the microstructure of normal and diseased arteries. The capabilities of OCT are well suited for the identification of calcified plaque and neointima formation after stent implantation. It has been reported that OCT-guided percutaneous coronary intervention (PCI) resulted in equivalent clinical and angiographic outcomes in comparison with IVUS-guided PCI. Recently, the three-dimensional reconstruction of OCT and a ...

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      Mentions: Kawasaki Medical School Shiro Uemura Teruyoshi Kume

    5. Optical Coherence Tomography Features Preceding the Onset of Advanced Age-Related Macular Degeneration

      Explore IOVS Journal Ophthalmology
      Optical Coherence Tomography Features Preceding the Onset of Advanced Age-Related Macular Degeneration

      Purpose : Age-related macular degeneration (AMD) is a progressive disease with multifactorial etiology. There is a need to identify clinical features that are harbingers of advanced disease. We evaluated morphologic features of the retina and choroid on optical coherence tomography (OCT) to determine if they predict progression to advanced disease. Methods : Progressors transitioned from early or intermediate AMD to advanced disease ( n = 40 eyes), and were matched on baseline AMD grade and follow-up interval to nonprogressors who did not develop advanced AMD ( n = 40 eyes). Features of the neurosensory retina, photoreceptors, retinal pigment epithelium (RPE), and choroid were evaluated. Logistic regression ...

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      Mentions: Tufts University Daniela Ferrara

    6. Deep-learning based, automated segmentation of macular edema in optical coherence tomography

      Explore OSA | OSA Publishing Ophthalmology
      Deep-learning based, automated segmentation of macular edema in optical coherence tomography

      Evaluation of clinical images is essential for diagnosis in many specialties. Therefore the development of computer vision algorithms to help analyze biomedical images will be important. In ophthalmology, optical coherence tomography (OCT) is critical for managing retinal conditions. We developed a convolutional neural network (CNN) that detects intraretinal fluid (IRF) on OCT in a manner indistinguishable from clinicians. Using 1,289 OCT images, the CNN segmented images with a 0.911 cross-validated Dice coefficient, compared with segmentations by experts. Additionally, the agreement between experts and between experts and CNN were similar. Our results reveal that CNN can be trained to ...

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      Mentions: University of Washington

    7. Uncovered Culprit Plaque Ruptures in Patients With ST-Segment Elevation Myocardial Infarction Assessed by Optical Coherence Tomography and Intravascular Ultrasound With iMap

      Explore ScienceDirect Cardiology
      Uncovered Culprit Plaque Ruptures in Patients With ST-Segment Elevation Myocardial Infarction Assessed by Optical Coherence Tomography and Intravascular Ultrasound With iMap

      Objectives This study assessed the incidence and course of healing of uncovered plaque ruptures (PR) following primary percutaneous coronary intervention. Background The infarct-related occlusion is frequently located at the lesion site with maximum thrombus burden, whereas the culprit PR may be situated more proximally or distally. Methods Uncovered PR in segments adjacent to the stent were identified by optical coherence tomography and intravascular ultrasound using iMap (Boston Scientific, Marlborough, Massachusetts) within 48 h and after 12 months. The percentages of necrotic core, fibrotic tissue, lipid tissue, and calcific tissue were determined. Results Eleven uncovered PR were found in 10 of ...

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    8. Retinal Loop Vessel Captured with Optical Coherence Tomography-Angiography

      Explore Ophthalmology Ophthalmology
      Retinal Loop Vessel Captured with Optical Coherence Tomography-Angiography

      A 50-year-old woman with a history of rheumatoid arthritis and macular hydroxychloroquine toxicity presented for a routine eye examination. An incidental loop vessel of the inferior prepapillary arteriole was readily apparent on examination (Fig 1 A ). Three-dimensional optical coherence tomography (OCT; Avanti, Optovue, Fremont, CA) demonstrated the elevation of this vessel into the vitreous (Fig 1 B ). The vessel was also captured on OCT-angiography (Fig 1 C ) with segmentation of the superficial retina and vitreous interface demonstrated by the B-scan image (inset). Retinal loop vessels are a common incidental finding on ophthalmic examination, but they can also be associated with ...

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      Mentions: Optovue Harvard University Massachusetts Eye and Ear Infirmary

    9. Optical Coherence Tomography Imaging of a Large Spherical Seed in Retinoblastoma

      Explore Ophthalmology Ophthalmology
      Optical Coherence Tomography Imaging of a Large Spherical Seed in Retinoblastoma

      The clinical applications of handheld optical coherence tomography (OCT) imaging (Bioptigen, Morrisville, NC) for retinoblastoma continue to evolve and include characterization of small tumors, tumor recurrences, evaluation of seeding, and retinal anatomy. OCT was performed at staging examination of the left eye in a 13-month-old child diagnosed with bilateral retinoblastoma (Group C right eye, Group D left eye) demonstrated normal foveal architecture, preretinal dusting of small hyper-reflective seeds, and a hollow reflective cystic structure floating above the retina, with shadowing posteriorly, which correlated clinically with a large translucent spherical seed in the vitreous cavity (Fig 1, asterisk).

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      Mentions: Bioptigen

    10. Very early great saphenous vein graft aneurysm treated by percutaneous coronary intervention under ChromaFlo imaging guidance

      Explore casereports.bmj.com Cardiology
      Very early great saphenous vein graft aneurysm treated by percutaneous coronary intervention under ChromaFlo imaging guidance

      A 73-year-old man, who had undergone coronary artery bypass grafting (CABG) 10 days prior, presented with a great saphenous vein graft aneurysm (SVGA). CT revealed the increasing size of the aneurysm. Since the SVGA occurred immediately after CABG and there were no other complications, the aneurysm was treated percutaneously. While intravascular ultrasonography (IVUS) and optical coherence tomography failed to detect the entry point, an IVUS catheter with the addition of ChromaFlo imaging clearly revealed the entry point, size and length of the SVGA. To prevent migration and edge restenosis associated with covered stents, the covered stent (3.0×19 mm ...

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    13. Method for reducing the dimensionality of a spatially registered signal derived from the optical properties of a sample, and device therefor

      Explore uspto.gov Patents
      Method for reducing the dimensionality of a spatially registered signal derived from the optical properties of a sample, and device therefor

      At least one embodiment of the method is designed to create a two-dimensional image of a three-dimensional sample. The method comprises the following steps: provision of a wave-length-tunable light source (1) that emits primary radiation (P) with wavelengths that vary over time; sampling of location points of the sample (2) with the primary radiation (P); collection of secondary radiation (S), wherein the secondary radiation (S) is a part of the primary radiation (P) reflected by the sample (2); creation of an interferometer-based detection signal for a plurality of sample areas, each with at least one location point, using a detection ...

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      Mentions: Robert A. Huber Wolfgang Wieser Thomas Klein

    14. Lens-free all-fiber probe with an optimized output beam for optical coherence tomography

      Explore OSA | OSA Publishing Probes
      Lens-free all-fiber probe with an optimized output beam for optical coherence tomography

      A high-efficiency lensless all-fiber probe for optical coherence tomography (OCT) is presented. The probe is composed of a segment of large-core multimode fiber (MMF), a segment of tapered MMF, and a length of single-mode fiber (SMF). A controllable output beam can be designed by a simple adjustment of its probe structure parameters (PSPs), instead of the selection of fibers with different optical parameters. A side-view probe with a diameter of 340 μm and a rigid length of 6.37 mm was fabricated, which provides an effective imaging range of ∼ 0.6    mm ∼0.6  mm with a full width at ...

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      Mentions: Zhihua Ding Zhejiang University Yi Shen

    15. Assessment of bioresorbable scaffold with a novel high-definition 60 MHz IVUS imaging system: Comparison with 40-MHz IVUS referenced to optical coherence tomography

      Explore Wiley Online Library Cardiology
      Assessment of bioresorbable scaffold with a novel high-definition 60 MHz IVUS imaging system: Comparison with 40-MHz IVUS referenced to optical coherence tomography

      Background In vivo assessment of bioresorbable scaffold (BRS) is of growing clinical interest. The novel 60MHz high-definition intravascular ultrasound (HD-IVUS) has been developed to overcome the limitations of conventional 40 MHz IVUS. This study aimed to evaluate the performance and limitations of 60 MHz HD-IVUS compared with 40 MHz IVUS with respect to polymeric-strut visualization, quantitative and qualitative analysis, and feasibility of high-speed pullback in the assessment of BRS. Methods and Results In a bench-test model, 361 struts were analyzed to evaluate the influence of ultrasound-beam angles and proximity of adjacent struts on IVUS visualization of BRS struts. Various settings ...

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      16. See all articles
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    Viewing a Weld Seam in 360°: New Scan Solution Utilizes OCT Technology to Coaxially Track and Inspect Seams Highly phase-stable 200 kHz swept-source optical coherence tomography based on KTN electro-optic deflector Two Engineering Openings at Startup Company Opticent Health Complex decorrelation averaging in optical coherence tomography: a way to reduce the effect of multiple scattering and improve image contrast in a dynamic scattering medium Michelson Diagnostics Secures CPT codes for Optical Coherence Tomography Imaging of Skin Murine chronic lymph node window for longitudinal intravital lymph node imaging Assessment of the radiofrequency ablation dynamics of esophageal tissue with optical coherence tomography Optical coherence tomography angiography of retinal vascular occlusions produced by imaging-guided laser photocoagulation Global Business Lead in OCT Imaging Opening at Leica Microsystems Assessment of acquired mucociliary clearance defects using micro-optical coherence tomography Can OCT Angiography Be Made a Quantitative Blood Measurement Tool? Tunable laser array system

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    8. Research by our group at MIT and our collaborators at Praevium Research and Thorlabs indicated that the coherence length of the VCSEL source was orders of magnitude longer than other swept laser technologies suitable for OCT, which suggested the possibility of long-range OCT imaging.
      By Benjamin M. Potsaid
    9. Our study demonstrates world-record results in cubic meter volume imaging, with at least an order of magnitude larger depth range and volume compared to previous demonstrations of three-dimensional OCT...These results provide a proof-of-principle demonstration for using OCT in this new regime...Long-range OCT is a new range of operation that requires extremely high performance light sources, integrated optical receivers and signal processing.
      By James G. Fujimoto
    10. Research by our group at MIT and our collaborators at Praevium Research and Thorlabs indicated that the coherence length of the VCSEL source was orders of magnitude longer than other swept laser technologies suitable for OCT, which suggested the possibility of long-range OCT imaging.
      By Benjamin M. Potsaid