Optical Coherence Tomography News

Feature Of The Week: Growth Kinetics of Concave Nanocubes Studied by Optical Coherence Tomography

This work presents the analysis of the growth kinetics of two syntheses of concave gold nanocubes with a mean size of 72 and 108 nm followed by the optical coherence tomography (OCT) technique by acquiring B-scan images each 5 s. In addition, ultra violet-visible (UV-Vis) spectra and mean size from dynamic light scattering (DLS) were acquired during nanoparticle growth to generate kinetic plots in order to corroborate the OCT results. Kinetic plots from OCT images were obtained by plotting contrast enhancement of B-scan images as function of time. Fitting parameters values given by using the classical Kolmogorov-Johnson-Mehl-Avrami (KJMA) equation show that the growth rate parameter k is higher for small cubes than for large ones, and that the Avrami exponent n associated to the growth kinetics of concave nanocubes is close to 2 for both syntheses. The results of UV-Vis spectroscopy and DLS confirm that OCT is a viable technique to provide information about nanoparticle growth kinetics. Moreover, to our knowledge, this is the first time that OCT technique is used to follow nanoparticle growth kinetics.

For more information see recent Article. Courtesy Yenisey Ponce de León from the Centro de Investigaciones en Óptica, A.C. To share this article click Here.
Featured Articles
1. Two Postdoctoral Positions in Optical imaging at Casey Eye Institute, Oregon Health & Science University, Portland, OR, USA
  
  Explore Optical Coherence Tomography News 20 hours, 20 min ago Ophthalmology , Jobs & Studentships
  
  The Center for Ophthalmic Optics and Lasers www.COOLLab.net , Casey Eye Institute, Oregon Health & Science University, is seeking outstanding candidates for the following positions in optical imaging research in the field of ophthalmology. v Post-Doc (hardware): develop optical imaging instruments Requirements: Skills in optics (optical design, microscope or fiber optics). Experience of programming with C++ or LabView for data acquisition and equipment control. Experience of optical coherence tomography (OCT) is desirable but not a must. PhD degree in a relevant discipline (Optics, Electrical Engineering, Biomedical Engineering, Physics). The successful candidate will be supervised by David Huang, MD, PhD and ...
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  Mentions: David Huang Oregon Health & Science University Center for Ophthalmic Optics and Lasers
2. Swept-source OCT and glaucoma
  
  Explore eyeworld.org Apr 18 2014 Ophthalmology , Tunable Sources
  
  A technology being investigated for use in posterior segment imaging may have a role in glaucoma diagnosis, according to the literature First there was time-domain optical coherence tomography (TD-OCT), then spectral-domain OCT (SD-OCT); now a newer technology—swept-source OCT—may be able to image structures that the previous technologies could not, according to researchers involved in clinical studies of the device. "With swept-source technology, a frequency swept light source and a high speed detector are used to detect the interference signal as a function of time, instead of a spectrometer and camera as in spectral-domain technology," explained James G. Fujimoto ...
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  Mentions: University of Pittsburgh Massachusetts Institute of Technology James G. Fujimoto
3. Intra-operative OCT devices for ophthalmic use: an overview
  
  Explore Home - Springer Apr 17 2014 Ophthalmology
  
  It is feasible to bring the currently most used examination method in ophthalmology, optical coherence tomography (OCT), into ophthalmic surgery to enhance information and control for the surgeon and increase outcome for the patient. In this overview, the currently commercially available OCT devices intending intra-operative OCT imaging are described. Further experience with these systems might not only aid in solving current problems but also open our minds to detect processes so far unknown and help answer questions so far unaddressed.
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  Mentions: Optovue Heidelberg Engineering Cornell University
4. Measurement of wavefront aberrations and lens deformation in the accommodated eye with optical coherence tomography-equipped wavefront system
  
  Explore opticsinfobase.org Apr 16 2014 Ophthalmology
  
  To quantitatively approach the relationship between optical changes in an accommodated eye and the geometrical deformation of its crystalline lens, a long scan-depth anterior segment OCT equipped wavefront sensor was developed and integrated with a Badal system. With this system, accommodation was stimulated up to 6.0D in the left eye and also measured in the same eye for three subjects. High correlations between the accommodative responses of refractive power and the radius of the anterior lens surface were found for the three subjects (r>0.98). The change in spherical aberration was also highly correlated with the change in ...
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  Mentions: Jianhua Wang University of Miami
5. Virtual reality simulator for vitreoretinal surgery using integrated OCT data
  
  Explore Medical Journals Publisher Apr 15 2014 Ophthalmology
  
  Operative practice using surgical simulators has become a part of training in many surgical specialties, including ophthalmology. We introduce a virtual reality retina surgery simulator capable of integrating optical coherence tomography (OCT) scans from real patients for practicing vitreoretinal surgery using different pathologic scenarios.
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  Mentions: Igor Kozak
6. Assessment of early occlusal caries pre- and post- sealant application—An imaging approach
  
  Explore Wiley Online Library Apr 15 2014 Dentistry
  
  Background and Objective Clinicians have difficulty assessing and monitoring early occlusal caries. Traditional clinical exam and radiographs are unable to detect the subtle alterations in enamel indicative of de- or re-mineralization, particularly under dental sealants. Although clinicians have used laser fluorescence (LF) to address this gap, this modality has demonstrated weak correlation with histology. The International Caries Detection and Assessment System (ICDAS-II) has demonstrated high sensitivity and specificity for caries detection, but since it is based on visual assessment, it is of no use in areas beneath the most commonly used dental sealants which are opaque. Optical coherence tomography (OCT ...
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  Mentions: University of Michigan Zhongping Chen UC Irvine
7. Optical frequency domain imaging in patients with Barrett's neoplasia: an ex vivo case study with correlated endoscopic and histology views
  
  Explore Gastrointestinal Endoscopy Apr 13 2014 Gastroenterology
  
  This video (, available online at www.giejournal.org) describes the optical frequency domain interferometry (OFDI) imaging technique, which is a U.S. Food and Drug Administration–approved and commercially available second-generation of optical coherence tomography, and its close correlation with endoscopic views and histopathology results in patients with Barrett's esophagus.
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  Mentions: FDA
8. Postdoctoral Associate Position in Biophotonics at Stanford University
  
  Explore Optical Coherence Tomography News Apr 11 2014 Jobs & Studentships
  
  The Stanford Biomedical Optics Group (PI: Audrey K Ellerbee), in collaboration with clinical researchers in the School of Medicine (urology and embryology), seeks highly motivated postdoctoral candidates with a strong experimental background and solid theoretical preparation in optics, microscopy, medical imaging and image processing. Stanford University provides an outstanding environment for solid technical research with clinical impact. A postdoctoral position is available related to active research in the following areas: optical coherence tomography, endoscopic probe development, spectroscopy. Start date: Immediate. Term: Up to 2 years. Requirements: Applicants should have received a Ph.D. in Electrical Engineering, Physics / Applied Physics, Optics ...
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  Mentions: Stanford University Audrey K. Ellerbee
9. Expanding OCT: Quanitifying the Cornea’s Optical Performance
  
  Explore osa-opn.org Apr 11 2014 Ophthalmology
  
  Optical coherence tomography, a well-known method for imaging the retina, may allow physicians to perform quantitative metrology of the eye’s own optics. Swept-source OCT allows for simultaneous imaging of the cornea, iris and retina in living patients. Laser refractive surgeries such as laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) have brought better vision to tens of millions worldwide. But these techniques also exact a cost: because they work by reshaping the eye’s cornea, they make accurate measurement of the cornea’s optical parameters after surgery unreliable using conventional tools. That’s important, not only because inaccurate ...
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  Mentions: Joseph A. Izatt Duke University
10. Postdoctoral Research Fellowships in Optical Coherence Tomography at Wellman Center for Photomedicine Massachusetts General Hospital
  
  Explore Optical Coherence Tomography News Apr 10 2014 Jobs & Studentships
  
  A Postdoctoral research fellowship in the area of In Vivo Microscopy is available in the Tearney Lab at the Massachusetts General Hospital (MGH) in the Wellman Center for Photomedicine. This appointment will be made at the rank of postdoctoral fellow at Harvard Medical School. MGH’s role as a leading teaching affiliate of Harvard Medical School and close ties to Harvard University and MIT provide an outstanding environment for developing and translating new in vivo microscopy technologies with applications in basic and clinical research. The fellowship will focus on the development and clinical application of advanced in vivo microscopy imaging ...
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  Mentions: Guillermo J. Tearney Massachusetts Institute of Technology Massachusetts General Hospital
11. Adaptive replanning intensity-modulated radiotherapy for choroidal metastasis of breast cancer using optical coherence tomography
  
  Explore Oxford Journals Apr 10 2014 Oncology
  
  Swept source optical coherence tomography (SS-OCT) is a convenient method for precise, early-stage detection of choroidal metastatic lesions, involving assessment of tumor response, and for regular follow-up studies. Using information obtained with SS-OCT, we performed intensity-modulated radiotherapy (IMRT) for a patient with choroidal metastasis from breast cancer with more accuracy than had been previously possible. We made replanning adaptive radiotherapy (ART) three times based on the rapid tumor shrinkage detected by weekly assessments with SS-OCT. Accordingly, the planning target volume (PTV) decreased from 1.6 cm 3 to 0.61 cm 3 (38%), with 0.95 cm 3 (59%) and ...
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  Mentions: Osaka University
12. St. Jude Medical Recognized as Innovative Technology Supplier of the Year by Nation’s Largest Health Care Contracting Organization
  
  Explore Optical Coherence Tomography News Apr 10 2014 Cardiology , Other Business News
  
  St. Jude Medical, Inc . ( STJ ), a global medical device company, was recognized by Novation as the 2013 Innovative Technology Supplier of the Year. Novation members selected the St Jude Medical ILUMIEN™ PCI Optimization System based on their experience using the technology to deliver improved patient outcomes. Novation works with its more than 100,000 members and affiliates to identify innovative technology that improves patient care or reduces the risk of harm to patients or providers, while simultaneously raising the standard of patient care and safety. “Novation’s goals of improving patient outcomes through innovative technology align with our mission at ...
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  Mentions: St. Jude Medical St. Jude Ilumien System
13. Business Forum: Professional society in our photonics ecosystem
  
  Explore Laser Focus World Apr 7 2014
  
  This is the second in a series of interviews of CEOs of our professional societies to give us a better understanding of the ecosystem of our industry. It is a pleasure for me to chat with Eugene Arthurs, someone I have known for more than 30 years. Arthurs is CEO of the International Society for Optics and Photonics after joining SPIE as executive director in 1999. Prior to this, he was president and CEO of Cleveland Crystals (CCI); before that, he was with Quantronix and Oriel. Arthurs received his B.Sc. with honors in Physics and his Ph.D. in ...
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  Mentions: California Institute of Technology Queen's University Belfast
14. Spatial Heterogeneity of Neoatherosclerosis, and its Relationship with Neovascularization and Adjacent Plaque Characteristics: Optical Coherence Tomography Study
  
  Explore American Heart Journal Apr 7 2014 Cardiology
  
  Background Development of neoatherosclerosis (NA) has been reported to be a potential cause of late stent failure. However, the distribution of NA and its relationship with neovascularization (NV) and adjacent plaque characteristics remain unclear. Methods We investigated 167 stents (40 bare-metal stents, 84 sirolimus-eluting stents, and 43 everolimus-eluting stents) with optical coherence tomography. Each stent was divided into the proximal section (PS), mid section (MS) and distal section (DS). NA was defined as lipid-laden neointima or calcification inside stent. Adjacent plaque characteristics were evaluated within 5 mm proximal and distal reference segments. Results NA was more frequent in PS and ...
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  Mentions: University of Pittsburgh Massachusetts General Hospital Ik-Kyung Jang
15. Imalux Ceases Operation
  
  Explore Optical Coherence Tomography News Apr 3 2014 Other Business News
  
  Imalux Corporation has announced that it has ceased operations due to various challenges to become a profitable on-going business. Imalux Corporation was one of the earliest OCT startup companies and received its first seed funding in 2000. Imalux opened operations in Cleveland Ohio with a strong technology connection to the Institute of Applied Physics in Russia. With the visionary leadership of Paul Amazeen and Felix Feldchtein Imalux developed the Niris product line that offered unique endoscopy imaging capabilities. Niris systems were delivered to customer's worldwide offering physicians the ability to identify structural changes in tissues, guide surgical interventions and ...
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  Mentions: Paul Amazeen Imalux Felix I. Feldchtein
16. International Workshop on Tissue Phantoms and Standardization in Biophotonics at University of Maryland, May 21, 2014
  
  Explore Optical Coherence Tomography News Apr 3 2014
  
  The primary objective of the proposed scientific exchange and conference program is to facilitate development of phantom-based test methods, build a foundation upon which rigorous, least burdensome consensus standards can be achieved and ensure FDA’s readiness to evaluate innovative and emerging optical imaging technologies. A number of key challenges will be addressed in the proposed workshop. Currently, there is a general lack of knowledge in the biophotonics field regarding international consensus standards, including their importance and the extent and type of effort required for their development. Greater understanding and appreciation will likely lead to an increase in the amount ...
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  Mentions: University of Maryland University of Pittsburgh National Institutes of Health
17. NIDEK Announces FDA Clearance of the RS-3000 Advance
  
  Explore Optical Coherence Tomography News Apr 2 2014 Ophthalmology , Other Business News
  
  NIDEK, Inc. a global leader in the design, manufacturing, and distribution of ophthalmic equipment, is pleased to announce FDA clearance of the RS-3000 Advance . This premier OCT system incorporating Scanning Laser Ophthalmoscope is designed for comprehensive evaluation of the retina and choroid. The RS-3000 Advance provides exquisite detail of the retinal and choroidal microstructures to assist in clinical diagnosis. Features include the choroidal mode, which allows detailed evaluation of the choroid. A wide area scan of 9 mm x 9 mm ensures excellent overall coverage of the retinal structures. Microsaccades and other involuntary eye movements are compensated by the Tracing ...
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  Mentions: Nidek FDA Nidek RS-3000
18. MedLumics Announces “BiopsyPen Project” with €3.6M EU in Funding; Initiative Aimed at New Clinical Applications for Optical Coherence Tomography
  
  Explore Optical Coherence Tomography News Mar 31 2014 Dermatology , Funding
  
  MedLumics , a medical imaging company specializing in advanced optical coherence tomography (OCT) technology, today announced the kick off of a three-year initiative to translate the latest OCT research into new clinical applications. Called the “BiopsyPen Project,” the effort is led by MedLumics and the Medical University of Vienna, with participation from a consortium of European members including VTT Finland, Delft University of Technology, Exalos AG, the Polytechnic University of Madrid, and Optocap Ltd. Together, the organizations are working to develop the second generation of a compact handheld diagnostic imaging system that will radically transform the capability of biophotonic technologies for ...
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  Mentions: Wolfgang Drexler Exalos Medical University of Vienna
19. NinePoint Medical Completes $34 Million Series B Financing to Expand Commercialization of its Breakthrough NvisionVLE™ Imaging System
  
  Explore Optical Coherence Tomography News Mar 19 2014 Gastroenterology , Funding , Other Business News
  
  NinePoint Medical, Inc. , an emerging leader in the development of medical devices for advanced optical imaging, today announced it has completed a $34 million Series B financing led by Corning Incorporated (NYSE: GLW), along with founding investors Third Rock Ventures and Prospect Venture Partners. The company also announced the addition of three new members to its board of directors: Curt Weinstein from Corning, and independent directors Tom Miller and Mark Stautberg. Proceeds from the financing will support the ongoing commercial launch of the NvisionVLE Imaging System in the U.S., as well as development of the company’s expanded product ...
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  Mentions: Massachusetts General Hospital Boston Scientific Siemens
20. Eric Swanson Hot Topics presentation: Clinical Translation in OCT: Role of Research, Funding, and Entrepreneurism
  
  Explore Home: SPIE.org Mar 16 2014
  
  Eric Swanson discusses the migration of optical coherence tomography (OCT) into clinical practice in, "Clinical Translation in OCT: Role of Research, Funding, and Entrepreneurism." The translation from research to successful clinical impact is challenging and often the process passes through several stages including product development, initial sales and product iteration, market growth, and, finally, the next generation products. Each step can take several years, requiring persistence and perseverance on the parts of technologists and investors alike. The first release of a reliable, manufacturable, and supportable commercial product into the hands of clinicians is a critical milestone. It allows for fine ...
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  Mentions: Massachusetts Institute of Technology Eric A. Swanson NinePoint Medical
21. See all articles
Recent Articles From Around The Web
1. Towards Extreme Ultra Violet Coherence Tomography with High Harmonic Generation Light Sources
  
  Explore opticsinfobase.org 20 hours, 10 min ago
  
  Optical coherence tomography (OCT) is a well-established method to retrieve three-dimensional, cross-sectional images of biological samples in a non-invasive way using near-infrared radiation. The axial resolution of OCT is on the order of the coherence length lc / 20 =FWHM which depends on the central wavelength 0 and the spectral width (FWHM) FWHM of a light source. As a consequence, the axial resolution only depends on the spectrum rather than the geometrical properties of the radiation. OCT with broadband visible and near-infrared sources typically reaches axial (depth) resolutions in the order of a few micrometers [1]. However, in contrast, extreme ultra ...
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2. Reproducibility of In-Vivo OCT Measured Three-Dimensional Human Lamina Cribrosa Microarchitecture
  
  Explore PLoS ONE Apr 18 2014 Ophthalmology
  
  Purpose To determine the reproducibility of automated segmentation of the three-dimensional (3D) lamina cribrosa (LC) microarchitecture scanned in-vivo using optical coherence tomography (OCT). Methods Thirty-nine eyes (8 healthy, 19 glaucoma suspects and 12 glaucoma) from 49 subjects were scanned twice using swept-source (SS−) OCT in a 3.5×3.5×3.64 mm (400×400×896 pixels) volume centered on the optic nerve head, with the focus readjusted after each scan. The LC was automatically segmented and analyzed for microarchitectural parameters, including pore diameter, pore diameter standard deviation (SD), pore aspect ratio, pore area, beam thickness, beam thickness SD, and ...
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  Mentions: University of Pittsburgh Massachusetts Institute of Technology James G. Fujimoto
3. Expectations and limitations of contemporary intravascular imaging: lessons learned from pathology
  
  Explore Informa Healthcare Apr 18 2014 Cardiology
  
  Acute coronary syndrome is the leading cause of death worldwide and plaque rupture is the most common underlying mechanism of coronary thrombosis. During the last 2 decades the understanding of atherosclerotic plaque progression advanced dramatically and pathology studies provided fundamental insights of underlying plaque morphology, which paved the way for invasive imaging modalities, which bring a new area of atherosclerotic plaque characterization in vivo. The development of intravascular ultrasound (IVUS) allowed the field to evaluate the principles of vascular anatomy, which is often underestimated by coronary angiography. Furthermore, IVUS image technologies were developed to obtain improved characterization of plaque composition ...
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  Mentions: Cardiovascular Research Foundation Renu Virmani Michael Joner
4. Orthogonal dispersive spectral-domain optical coherence tomography
  
  Explore opticsinfobase.org Apr 18 2014 Ophthalmology
  
  Ultrahigh depth range spectral domain optical coherence tomography (SDOCT) can be realized based on the orthogonal dispersive spectrometer consisted by a high spectral resolution virtually-imaged phased array (VIPA) and a low spectral resolution grating. However, two critical issues result in the challenge of obtaining desirable one-dimensional (1-D) spectra from the recorded two-dimensional (2-D) orthogonal spectra for high-quality OD-SDOCT imaging. One is the wavenumber mapping errors and the other is the periodic intensity modulations. The paper proposes a method for desirable reconstruction of 1-D spectra from the recorded 2-D orthogonal spectra. A sample etalon with identical parameters to the dispersive VIPA ...
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  Mentions: Zhihua Ding Zhejiang University
5. Simultaneously measuring the refractive index and thickness of an optical sample by using improved fiber-based optical coherence tomography
  
  Explore SPIE | Journal Apr 17 2014
  
  $Simultaneously measuring the refractive index and thickness of an optical sample by using improved fiber-based optical coherence tomography$
  An improved structure for the optical coherence tomography (OCT) scheme based on a 4 × 4 fiber coupler for simultaneously measuring the refractive index and thickness of optical samples is presented. The proposed structure incorporates the optical path length difference of interference light and is used to calculate the refractive index and thickness of an unknown sample without any prior knowledge of the sample parameters. Two methods (time-domain and Fourier-domain OCT) of obtaining information about an unknown sample are proposed, and a high-speed high-resolution OCT system was developed.
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  Mentions: Hsu-Chih Cheng
6. Optical Coherence Tomography-guided Bifurcation Stenting of a Coronary Artery Dissection
  
  Explore ScienceDirect Apr 17 2014 Cardiology
  
  Periprocedural guide-wire induced coronary artery dissection is a rare but potentially serious complication of PCI. Immediate stenting of the entry point is one of the therapeutic options but engaging the guide-wire in the true lumen may be challenging. We report a case of a 55-year-old woman with a guide-wire induced coronary dissection that occurred during treatment of a bifurcation lesion. Optical coherence tomography was instrumental to distinguish true form false lumen and thereby guide correct positioning of the guide-wire to successfully treat the lesion using a dedicated bifurcation stent.
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  Mentions: Evelyn Regar Erasmus Medical Center Jurgen M. Ligthart
7. Preservation of the Photoreceptor Layer following Subthreshold Laser Treatment for Diabetic Macular Edema as Demonstrated by SD-OCT
  
  Explore iovs.org Apr 17 2014 Ophthalmology
  
  Purpose: Subthreshold laser treatment of diabetic macular edema (DME) may have less deleterious effects on the photoreceptors than regular continuous wave laser. This study aimed to assess whether subthreshold laser causes a long-term damage to the retinal structures, as demonstrated by spectral-domain optical coherence tomography (SD-OCT), and to evaluate the change in the axial diameter of retinal diabetic microaneurysms following treatment. Methods: A retrospective study of eyes that were diagnosed with non-foveal involving DME and underwent subthreshold laser treatment with the Lumenis Novus SRT system. SD-OCT scans of treated retinal areas, performed prior to treatment and approximately 4 months following ...
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8. Hyperreflective Pyramidal Structures on Optical Coherence Tomography in Geographic Atrophy Areas
  
  Explore LWW Online Apr 17 2014 Ophthalmology
  
  Purpose: We observed hyperreflective dome-shaped or pyramidal structures (HPS) on spectral domain optical coherence tomography (SD-OCT) in patients affected with geographic atrophy (GA). Our purpose was to describe the multimodal imaging features of HPS identified in areas of GA in patients with age-related macular degeneration. Methods: This is a retrospective case series of patients with GA harboring HPS in atrophic areas. Multimodal imaging examination including infrared reflectance, fundus autofluorescence, and SD-OCT, was performed for each patient. Infrared and fundus autofluorescence appearance and mean SD-OCT height of HPS in GA were analyzed. Results: A total of 36 eyes of 25 patients ...
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  Mentions: Centre Hospitalier Intercommunal de Créteil Giuseppe Querques Eric H. Souied
9. Potential new diagnostic tool for Alzheimer's disease using a linear discriminant function for Fourier domain optical coherence tomography
  
  Explore iovs.org Apr 17 2014 Neurology , Ophthalmology
  
  Purpose: To calculate and validate a linear discriminant function (LDF) for Fourier domain optical coherence tomography (OCT) to improve the diagnostic ability of retinal and retinal nerve fiber layer (RNFL) thickness parameters in the detection of Alzheimer's disease (AD). Method: AD patients (n=151) and age-matched, healthy subjects (n=61) were enrolled. The Cirrus and Spectralis OCT systems were used to obtain retinal measurements and circumpapillary RNFL thickness for each participant. A LDF was calculated using all retinal and RNFL OCT measurements. Receiver operating characteristic (ROC) curves were plotted and compared among the LDF and the standard parameters provided ...
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  Mentions: Miguel Servet University Hospital Zeiss Cirrus HD-OCT José M. Larrosa
10. Vitreous Hyper-Reflective Dots in Optical Coherence Tomography and Cystoid Macular Edema after Uneventful Phacoemulsification Surgery
  
  Explore PLoS ONE Apr 17 2014 Ophthalmology
  
  Purpose To report the observation of hyper-reflective dots in the vitreous cavity using spectral domain optical coherence tomography (SD-OCT) after uneventful phacoemulsification cataract surgery and to investigate their association with cystoid macular edema (CME). Materials and Methods Medical records of consecutive Asian patients who had no preoperative retinopathy and underwent uneventful phacoemulsification cataract surgery from March 2012 through February 2013 were reviewed. SD-OCTs were performed before, 1 week, and 1 month after surgery. The number of vitreous hyper-reflective dots (VHDs) was counted in 5 OCT images of high-definition 5-line raster scans. The development of CME was assessed using postoperative 1-month ...
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  Mentions: Harvard University Carl Zeiss Meditec Zeiss Cirrus HD-OCT
11. High Power Laser Sources At Exotic Wavelengths
  
  Explore Photonics Online Apr 16 2014
  
  High power laser sources at exotic wavelengths may be a step closer as researchers in China report a fibre optic parametric oscillator with record breaking efficiency. The research team believe this could lead to new light sources for a range of biomedical imaging applications. Mature commercial laser platforms are available for common output wavelengths. Some applications, however, require wavelengths that cannot readily be produced with established technologies. Several of these are in the field of biomedical imaging and spectroscopy (e.g. coherent anti-Stokes Raman scattering microscopy and optical coherence tomography). In such systems if the wavelength of light used can ...
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12. Advancing OCT Algorithmic Standardization
  
  Explore iovs.org Apr 15 2014 Ophthalmology
  
  Neovascular exudative AMD (wet AMD) continues to rank as a top reason to visit eye care specialists, and the early identification of this disease has important prognostic implications for patients. 1 Advancements in optical coherence tomography (OCT) imaging have surpassed other modalities in the ability to detect the earliest development of wet AMD and prompt treatment initiation, in spite of lack of inter- and intradevice standardization. 2 , 3 Zhang et al. 4 present a novel, automated way to detect changes at the border where choroidal neovascularization (CNV) first affects the retina. They use a technique that presents an automated method ...
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13. Phase correction using programmable phase modulator (PPM) in optical coherence tomography
  
  Explore Home - Springer Apr 15 2014
  
  Purpose Adaptive optics is used in optical coherence tomography (OCT) in order to improve lateral resolution based on aberration correction. Methods Experiments were performed to compensate higher order aberrations based on wavefront sensing and correction scheme using adaptive optics. The device utilized for compensation is parallel-aligned nematic liquid crystal spatial light modulator (PAL-SLM), PPM X7550 series. Wavefront of light at the sample path was measured by using OCT for aberration correction. Since the phase information can be obtained from interferogram therefore no additional optics is used. The performance of this device is evaluated for the correction of linear tilt aberration ...
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  Mentions: Jeehyun Kim Kyungpook National University
14. Full-range Fourier domain Doppler optical coherence tomography based on sinusoidal phase modulation
  
  Explore opticsinfobase.org Apr 15 2014 Velocimetry
  
  A novel full-range Fourier domain Doppler optical coherence tomography (full-range FD-DOCT) using sinusoidal phase modulation for B-M scan is proposed. In this sinusoidal B-M scan, zero optical path difference (OPD) position does not move corresponding to lateral scanning points in contrast to linear B-M scan. Since high phase sensitivity arises around the zero OPD position, the proposed full-range FD-DOCT can achieve easily high velocity sensitivity without mirror image around the zero OPD position. Velocity sensitivity dependent on the OPD and the interval of scanning points is examined, and flow velocity detection capability is verified through Doppler imaging of a flow ...
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  Mentions: Carl Zeiss Meditec Osami Sasaki Xiangzhao Wang
15. Optical coherence tomography characteristics of the iris in Cogan-Reese syndrome
  
  Explore eur-j-ophthalmol.com Apr 15 2014 Ophthalmology
  
  PurposeTo describe the characteristic optical coherence tomography (OCT) findings of the iris in Cogan-Reese syndrome.MethodsA 63-year-old woman was referred for consultation due to diffuse pigmentation of the iris and elevated intraocular pressure (IOP) in the left eye. The clinical examination revealed Cogan-Reese syndrome with pedunculated iris outcroppings on the entire iris surface, and no peripheral anterior synechia. The right eye was normal with normal IOP.ResultsImaging the left iris with the CAM-L cornea lens adapter of the Optovue Fourier-domain OCT (RTVue-OCT) showed a folded iris surface, an increased total iris thickness, and an increased distance between the anterior and ...
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  Mentions: Optovue Optovue RTVue-100 Semmelweis University