1. Featured Articles

    1. AI-Assisted In Situ Detection of Human Glioma Infiltration Using a Novel Computational Method for Optical Coherence Tomography

      Explore Clinical Cancer Research Neurology
      AI-Assisted In Situ Detection of Human Glioma Infiltration Using a Novel Computational Method for Optical Coherence Tomography

      Purpose: In glioma surgery, it is critical to maximize tumor resection without compromising adjacent non-cancerous brain tissue. Optical Coherence Tomography (OCT) is a non-invasive, label-free, real-time, high-resolution imaging modality that has been explored for glioma infiltration detection. Here we report a novel artificial intelligence (AI) assisted method for automated, real-time, in situ detection of glioma infiltration at high spatial resolution. Experimental Design: Volumetric OCT datasets were intraoperatively obtained from resected brain tissue specimens of 21 patients with glioma tumors of different stages and labeled as either non-cancerous or glioma-infiltrated based on histopathology evaluation of the tissue specimens (gold standard). Labeled ...

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      Mentions: Johns Hopkins University Texas A&M University Javier A. Jo

    2. Motorized capsule for shadow-free OCT imaging and synchronous beam control

      Explore OSA | OSA Publishing Gastroenterology , Probes
      Motorized capsule for shadow-free OCT imaging and synchronous beam control

      We demonstrate a tethered motorized capsule for unobstructed optical coherence tomography (OCT) imaging of the esophagus. By using a distal reflector design, we avoided the common shadow artifact induced by the motor wires. A synchronous driving technique features three types of beam-scanning modes of the capsule, i.e., circumferential beam scanning, localized beam scanning, and accurate beam positioning. We characterized these three modes and carried out ex vivo imaging experiments using the capsule. The results show that the capsule can potentially be a useful tool for diagnostic OCT imaging and OCT-guided biopsy and therapy of the esophagus.

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      Mentions: Brett E. Bouma Massachusetts General Hospital Harvard University

    3. ZEISS Marks Milestone for its New North America High Tech Site in Dublin, California

      Explore ZEISS United States Other Business News
      ZEISS Marks Milestone for its New North America High Tech Site in Dublin, California

      The internationally leading optics and optoelectronics technology enterprise ZEISS completed the “steel topping out” phase of its new high tech site in the San Francisco Bay Area. The new site in Dublin is an integral part of ZEISS’ global investment strategy and is one element in a string of international projects aimed at expanding, modernizing and realigning sites that ZEISS has been implementing in locations such as Germany, Europe and Asia since 2011. “Our investments are focused on leveraging the existing potential in our growth markets,” explains Dr. Christian Mueller, Member of the Executive Board and CFO of the ZEISS ...

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      Mentions: Carl Zeiss Meditec

    4. Using Optical Coherence Tomography to Make Needle Biopsies Safer

      Explore Journals Probes
      Using Optical Coherence Tomography to Make Needle Biopsies Safer

      Stereotactic needle biopsy continues to be widely employed in the diagnosis of intracranial lesions. Despite an overall low complication rate, hemorrhage remains one the most common and potentially serious risks of the procedure. Previous series have reported a symptomatic hemorrhage rate of 3% to 6%, with a minority requiring craniotomy and hemorrhage evacuation. 1-4 Though certain factors inherent to the lesion or the patient have been known to increase hemorrhage risk, 2 , 3 up until this point there has been little that surgeons can do intraoperatively to avoid hemorrhage after a trajectory has been selected. A new report in Science ...

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      Mentions: Brigham and Women’s Hospital Harvard University

    5. Identification of Retinal Biomarkers in Alzheimer’s Disease Using Optical Coherence Tomography: Recent Insights, Challenges, and Opportunities

      Explore MDPI Open Access Journals Platform Ophthalmology
      Identification of Retinal Biomarkers in Alzheimer’s Disease Using Optical Coherence Tomography: Recent Insights, Challenges, and Opportunities

      This review will highlight recent insights into measuring retinal structure in Alzheimer’s disease (AD). A growing body of evidence indicates that disturbances in retinal blood flow and structure are related to cognitive function, which can severely impair vision. Optical coherence tomography (OCT) is an optical imaging technology that may allow researchers and physicians to gain deeper insights into retinal morphology and clarify the impact of AD on retinal health and function. Direct and noninvasive measurement of retinal morphology using OCT has provided useful diagnostic and therapeutic indications in several central nervous system (CNS) diseases, including AD, multiple sclerosis, and ...

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      Mentions: University of Miami Delia Cabrera DeBuc

    6. Senior Scientist on Topcon Milpitas California

      Explore Optical Coherence Tomography News Jobs & Studentships
      Senior Scientist on Topcon Milpitas California

      Overview Topcon is a comprehensive ophthalmic device manufacturer within the worldwide ophthalmic community. It introduced the world’s first commercial back-of-the-eye spectral domain (SD) and swept source (SS) optical coherence tomography (OCT) systems, which have driven innovation in eye-care. More recently, Topcon Healthcare Solutions started to enhance not only its hardware but also its software solutions. To become the leader in diagnostic software, Topcon has developed a new strategic division whose primary objective is to create world-class software solutions for the eye-care industry and beyond. Our products enable the collection and visualization of a wide range of imaging and clinical ...

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      Mentions: Topcon Medical Systems

    7. International Ocular Circulation Society Inaugural Meeting, August 10, 2019 Portland Oregon

      Explore Optical Coherence Tomography News Ophthalmology
      International Ocular Circulation Society Inaugural Meeting, August 10, 2019 Portland Oregon

      The International Ocular Circulation Society (IOCS) was co-founded by a group of leading researchers in America, Asia, and Europe in 2018. The inaugural meeting of the new Society will be hosted by David Huang, M.D. and Yali Jia, Ph.D. of the Casey Eye Institute in Portland Oregon on August 10, 2019. The meeting will present 28 papers and 35 posters on technologies on the topics of imaging and measurement of ocular blood flow and oxygen metabolism, vascular anatomy and physiology, and the roles of ocular circulation in retina, optic nerve, neurological, and systemic diseases. The Oregon Health & Science ...

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      Mentions: David Huang Oregon Health & Science University Center for Ophthalmic Optics and Lasers

    8. ZEISS Ophthalmic Digital Summit 2019

      Explore LMC Creative Ophthalmology , Other Business News
      ZEISS Ophthalmic Digital Summit 2019

      In partnership with ODwire, Carl Zeiss Meditec, Inc. and Carl Zeiss Vision invite you to the ZEISS Ophthalmic Digital Summit 2019 . This two-day complimentary program offers live sessions and an interactive product showcase—all within a virtual exhibit hall—designed to provide you with the latest technology innovations and clinical solutions for your practice. Taught by industry leaders , you'll get trained and informed on how the Integrated Diagnostic Imaging platform and ZEISS leading imaging technologies will help shape the future of your practice. Event attendees will also be eligible for special show promotions and discounts on ZEISS instruments.

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      Mentions: Carl Zeiss Meditec

    9. Bacterial Density and Biofilm Structure Determined by Optical Coherence Tomography

      Explore Nature Publishing Group
      Bacterial Density and Biofilm Structure Determined by Optical Coherence Tomography

      Optical-coherence-tomography (OCT) is a non-destructive tool for biofilm imaging, not requiring staining, and used to measure biofilm thickness and putative comparison of biofilm structure based on signal intensity distributions in OCT-images. Quantitative comparison of biofilm signal intensities in OCT-images, is difficult due to the auto-scaling applied in OCT-instruments to ensure optimal quality of individual images. Here, we developed a method to eliminate the influence of auto-scaling in order to allow quantitative comparison of biofilm densities in different images. Auto- and re-scaled signal intensities could be qualitatively interpreted in line with biofilm characteristics for single and multi-species biofilms of different strains ...

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    10. Handheld spectrally encoded coherence tomography and reflectometry for motion-corrected ophthalmic optical coherence tomography and optical coherence tomography angiography

      Explore SPIE Digital Library
      Handheld spectrally encoded coherence tomography and reflectometry for motion-corrected ophthalmic optical coherence tomography and optical coherence tomography angiography

      Optical coherence tomography (OCT) is the gold standard for quantitative ophthalmic imaging. The majority of commercial and research systems require patients to fixate and be imaged in a seated upright position, which limits the ability to perform ophthalmic imaging in bedridden or pediatric patients. Handheld OCT devices overcome this limitation, but image quality often suffers due to a lack of real-time aiming and patient eye and photographer motion. We describe a handheld spectrally encoded coherence tomography and reflectometry (SECTR) system that enables simultaneous en face reflectance and cross-sectional OCT imaging. The handheld probe utilizes a custom double-pass scan lens for ...

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      Mentions: Vanderbilt University Yuankai K. Tao

    11. Laser cleaning of paintings: in situ optimization of operative parameters through non-invasive assessment by optical coherence tomography (OCT), reflection FT-IR spectroscopy and laser induced fluorescence spectroscopy (LIF)

      Explore Heritage Science Art , NDE/NDT
      Laser cleaning of paintings: in situ optimization of operative parameters through non-invasive assessment by optical coherence tomography (OCT), reflection FT-IR spectroscopy and laser induced fluorescence spectroscopy (LIF)

      Nowadays the use of laser technology as a highly precise tool for the cleaning of paintings is gaining ground. The development of a non-invasive analytical protocol aimed at thorough assessment of the treated surfaces and real time monitoring of the laser cleaning action is thus becoming imperative. This ensures that no side effects (e.g. discoloration, darkening, blackening) will occur on the painting surfaces due to laser ablation. In the present study the potential of the combined use of optical coherence tomography (OCT) and reflection FT-IR spectroscopy for in situ non-invasive assessment of laser cleaning procedures has been investigated on ...

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      Mentions: Nicolaus Copernicus University Piotr Targowski Marcin Sylwestrzak

    12. Spatiotemporal Tracking of Brain-Tumor-Associated Myeloid Cells in Vivo through Optical Coherence Tomography with Plasmonic Labeling and Speckle Modulation

      Explore ACS Publications Home Page Neurology
      Spatiotemporal Tracking of Brain-Tumor-Associated Myeloid Cells in Vivo through Optical Coherence Tomography with Plasmonic Labeling and Speckle Modulation

      By their nature, tumors pose a set of profound challenges to the immune system with respect to cellular recognition and response coordination. Recent research indicates that leukocyte subpopulations, especially tumor-associated macrophages (TAMs), can exert substantial influence on the efficacy of various cancer immunotherapy treatment strategies. To better study and understand the roles of TAMs in determining immunotherapeutic outcomes, significant technical challenges associated with dynamically monitoring single cells of interest in relevant live animal models of solid tumors must be overcome. However, imaging techniques with the requisite combination of spatiotemporal resolution, cell-specific contrast, and sufficient signal-to-noise at increasing depths in tissue ...

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      Mentions: Stanford University Adam de la Zerda Elliott D. SoRelle
    13. See all articles

  2. Recent Articles From Around The Web

    1. Notal Vision Diagnostic Clinic reports completion of 6 million ForeseeHome AMD home-monitoring tests

      Explore Optical Coherence Tomography News Ophthalmology , Other Business News
      Notal Vision Diagnostic Clinic reports completion of 6 million ForeseeHome AMD home-monitoring tests

      Notal Vision, Inc., a company focused on advancing eye care with precision medicine by extending disease management from the clinic to the home, celebrates the completion of six million patient tests performed with ForeseeHome, the first FDA-cleared home-monitoring device for patients with intermediate dry Age-related Macular Degeneration (AMD) at risk for developing wet AMD. ForeseeHome uses a patented technology, Preferential Hyperacuity Perimetry® (PHP), that can identify minute changes in the central 14 degrees of visual field before the patient has any visual symptoms. During the test, which takes about three minutes, the central macula is evaluated for changes in metamorphopsia ...

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      Mentions: Notal Vision

    2. Monitoring retinal responses to acute intraocular pressure elevation in rats with visible light optical coherence tomography

      Explore SPIE Digital Library Ophthalmology
      Monitoring retinal responses to acute intraocular pressure elevation in rats with visible light optical coherence tomography

      Elevated intraocular pressure (IOP) is an important risk factor for glaucoma. However, the role of IOP in glaucoma progression, as well as retinal physiology in general, remains incompletely understood. We demonstrate the use of visible light optical coherence tomography to measure retinal responses to acute IOP elevation in Brown Norway rats. We monitored retinal responses in reflectivity, angiography, blood flow, oxygen saturation (sO2 ), and oxygen metabolism over a range of IOP from 10 to 100 mmHg. As IOP was elevated, nerve fiber layer reflectivity was found to decrease. Vascular perfusion in the three retinal capillary plexuses remained steady until IOP ...

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      Mentions: David Huang Oregon Health & Science University Yali Jia

    3. Optical Coherence Tomography-Angiography of Different Choroidal Neovascularization Subtypes in Wet Age-related Macular Degeneration

      Explore Home Ophthalmology
      Optical Coherence Tomography-Angiography of Different Choroidal Neovascularization Subtypes in Wet Age-related Macular Degeneration

      Age-related macular degeneration is a leading cause of irreversible vision loss in individuals over 55 years of age worldwide. Conventionally, it is divided into two subtypes – dry (non-neovascular) and wet (neovascular) form. Neovascular age-related macular degeneration comprises only 10-15% of all patients but is responsible for more than 80% of blindness related to the disease. It requires early diagnosis and timely treatment. Fluorescein angiography is the current ‘gold standard’ for diagnosing neovascular forms. However, as an invasive procedure, it may be contraindicated in some circumstances and cause serious adverse effects. Optical coherence tomography-angiography is a relatively new, non-invasive and fast ...

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    4. Optical Coherence Tomography Angiography of Macula in Chronic Anterior Ischaemic Optic Neuropathy Associated with Giant Cell Arteritis

      Explore Taylor & Francis Online Neurology , Ophthalmology
      Optical Coherence Tomography Angiography of Macula in Chronic Anterior Ischaemic Optic Neuropathy Associated with Giant Cell Arteritis

      A 74-year-old man presented with bilateral optic nerve atrophy related to arteritic anterior ischaemic optic neuropathy (AION) which started 22 years ago. Atrophic papilla was noted in both eyes and optical coherence tomography showed thinning of the retinal nerve fibres layer as well as the macular ganglion cell complex. Optical coherence tomography angiography of the macula found a decreased density of the superficial capillary complex, whereas deep capillary complex was well-preserved. Inner retinal layer atrophy in chronic arteritic AION is followed by a loss of vascularisation in these layers as a consequence of the neurodegeneration.

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    5. Impact of late stent malapposition after drug-eluting stent implantation on long-term clinical outcomes

      Explore atherosclerosis-journal.com Cardiology
      Impact of late stent malapposition after drug-eluting stent implantation on long-term clinical outcomes

      Background and aims The impact of late drug-eluting stent (DES) malapposition detected by optical coherence tomography (OCT) on long-term clinical outcomes has not been clearly established. We evaluated long-term clinical outcomes of late stent malapposition (LSM) detected by OCT in a qualified study population. Methods A total of 428 patients were selected from previous randomized OCT studies that evaluated the degree of strut coverage of different DESs at a 3–12-month follow-up OCT examination. These patients were assigned to one of two groups based on the presence (n = 136) or absence (n = 292) of LSM on follow-up OCT images (performed ...

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      Mentions: Yonsei University Jung-Sun Kim Dong Hoon Choi

    6. Vascular Responses After Percutaneous Coronary Intervention With Stenting In Patients With Obstructive Sleep Apnea

      Explore Home - ClinicalTrials.gov Cardiology , Clinical Trials
      Vascular Responses After Percutaneous Coronary Intervention With Stenting In Patients With Obstructive Sleep Apnea

      Obstructive sleep apnea (OSA) is an increasingly common chronic disorder in adults. Compared to the general population, OSA occurs more often in patients with coronary artery disease (CAD), with a reported prevalence of 38% to 65%. Emerging evidence indicates OSA initiates and exacerbates coronary atherosclerosis. Moreover, several observational studies indicate the presence of OSA was associated with higher rate of restenosis and repeat revascularization (mainly attributed non-culprit lesion revascularization) after percutaneous coronary intervention (PCI). OSA might initiate endothelial injury by repetitive bursts of sympathetic activity that occur with apneas and hypopneas. Moreover, untreated OSA reduces endothelial repair capacity. Whether OSA ...

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    7. Optical coherence tomography angiography findings in preeclampsia

      Explore Nature Publishing Group Ophthalmology
      Optical coherence tomography angiography findings in preeclampsia

      Objectives To investigate vascular density analysis in the superficial (SCP) and deep capillary plexus (DCP), foveal avascular zone (FAZ), peripapillary vascular density analysis (PPCVD), and peripapillary retinal nerve fiber thickness analysis (PPRNFL) using optical coherence tomography angiography (OCTA) in pregnant women with preeclampsia and to compare the obtained values with healthy pregnant and nonpregnant healthy individuals. Methods A total of 98 pregnant women (55 had preeclampsia, 43 were healthy pregnant women) and 38 healthy nonpregnant women of reproductive age were included in the study. The patients were divided into three groups. Group 1 consisted of pregnant women with preeclampsia, group ...

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    8. Image contrast correction method in full-field optical coherence tomography

      Explore SPIE Digital Library
      Image contrast correction method in full-field optical coherence tomography

      An image contrast correction method is proposed for en face images obtained with full-field optical coherence tomography (FFOCT). First, the mechanism of image contrast decrease in FFOCT is considered and the theoretical models of main parameters that degrade image contrast are analyzed. Second, changes of contrast with depth are calculated under various conditions, from which the main parameters that affect contrast in tissue are identified. Then based on the analysis, the methods are proposed for correcting image contrast. Finally, the en face tomographic images of human liver tissue at different depths with and without contrast correction are presented to demonstrate ...

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      Mentions: Wanrong Gao Nanjing University of Science and Technology

    9. Evaluation of posterior vitreous detachment using ultrasonography and optical coherence tomography

      Explore Wiley Online Library Ophthalmology
      Evaluation of posterior vitreous detachment using ultrasonography and optical coherence tomography

      Purpose To compare the diagnostic ability of ultrasonography (US) and optical coherence tomography (OCT) in evaluating posterior vitreous detachment (PVD) status. Methods In total, 124 eyes in 63 patients were prospectively enrolled. Posterior vitreous detachment (PVD) status was evaluated by two examiners independently using US and OCT (transverse scan with/without peripapillary scan). By combining all examination results from both examiners, a final agreement on the PVD status was made. Inter‐observer agreement and inter‐examination agreement on PVD detection were evaluated. Results The inter‐observer agreement on PVD grading based on US was substantial (kappa = 0.628). The inter ...

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    10. Optical coherence tomography angiography characteristics of acute retinal arterial occlusion

      Explore BMC Ophthalmology Ophthalmology
      Optical coherence tomography angiography characteristics of acute retinal arterial occlusion

      Background To characterize the vascular changes in eyes within the acute phase of retinal arterial occlusion (RAO) by optical coherence tomography angiography (OCT-A) imaging. Methods This was a retrospective, observational study. Nineteen patients with RAO (symptom onset within 7 days) and 19 age and sex-matched normal control individuals were included. A comprehensive ophthalmic examination and OCT-A examination were conducted for all the patients. Results The vessel density of the superficial capillary plexus (SCP), deep capillary plexus (DCP), and area with a width of 300 μm around the FAZ (FD-300) was significantly reduced in RAO patients compared with that in the ...

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      Mentions: Jing Xu

    11. Computed Tomography–Mediated Registration of Trapeziometacarpal Articular Cartilage Using Intraarticular Optical Coherence Tomography and Cryomicrotome Imaging: A Cadaver Study

      Explore SAGE Journals
      Computed Tomography–Mediated Registration of Trapeziometacarpal Articular Cartilage Using Intraarticular Optical Coherence Tomography and Cryomicrotome Imaging: A Cadaver Study

      Objective Accurate, high-resolution imaging of articular cartilage thickness is an important clinical challenge in patients with osteoarthritis, especially in small joints. In this study, computed tomography (CT) mediated catheter-based optical coherence tomography (OCT) was utilized to create a digital reconstruction of the articular surface of the trapeziometacarpal (TMC) joint and to assess cartilage thickness in comparison to cryomicrotome data. Design Using needle-based introduction of the OCT probe, the articular surface of the TMC joint of 5 cadaver wrists was scanned in different probe positions with matching CT scans to record the intraarticular probe trajectory. Subsequently and based on the acquired ...

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      Mentions: Academic Medical Center at the University of Amsterdam Ton G. van Leeuwen Daniël M. de Bruin

    12. Successful Treatment of Genital Warts with Ingenol Mebutate Monitored with Optical Coherence Tomography and Reflectance Confocal Microscopy

      Explore KoreaMed Synapse Dermatology
      Successful Treatment of Genital Warts with Ingenol Mebutate Monitored with Optical Coherence Tomography and Reflectance Confocal Microscopy

      Ingenol mebutate (IM) is approved for the treatment of actinic keratosis and induces cell death in precancerous lesions. The efficacy of IM in the treatment of genital warts was investigated in a therapy-refractory patient. The 74-year-old male was treated with IM gel for three consecutive days. Treatment course and efficacy were evaluated by clinical inspection and non-invasive diagnostics namely optical coherence tomography (OCT) and reflectance confocal microscopy (RCM). Within 24 to 48 hours IM induced a strong local inflammatory reaction. One week later a complete response was observed. OCT and RCM showed a strong reaction after treatment with erosions, swelling ...

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      Mentions: Kawasaki Medical School

    13. Comparison of peripapillary and subfoveal choroidal thickness in normal versus primary open-angle glaucoma (POAG) subjects using spectral domain optical coherence tomography (SD-OCT) and swept source optical coherence tomography (SS-OCT)

      Explore Home | BMJ Open Ophthalmology Ophthalmology
      Comparison of peripapillary and subfoveal choroidal thickness in normal versus primary open-angle glaucoma (POAG) subjects using spectral domain optical coherence tomography (SD-OCT) and swept source optical coherence tomography (SS-OCT)

      Objective To elucidate the difference between choroidal thickness (CT) in primary open-angle glaucoma (POAG) and normal subjects and to compare the CT measured using spectral domain optical coherence tomography (SD-OCT) and swept source optical coherence tomography (SS-OCT). Methods and analysis This cross-sectional observational study included 25 eyes of 17 POAG subjects (cases) and 31 eyes of 20 normal subjects (controls). All the patients underwent complete ophthalmologic examination, enhanced depth imaging, SD-OCT and SS-OCT. In both controls and cases, the CT was measured in seven predetermined points in macular and peripapillary area and were compared. Results Choroid was significantly thicker on ...

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      Mentions: L V Prasad Eye Institute Sirisha Senthil

    14. Methods for Quantifying Optic Disc Volume and Peripapillary Deflection Volume Using Radial Optical Coherence Tomography Scans and Association with Intracranial Pressure

      Explore Frontiers Ophthalmology
      Methods for Quantifying Optic Disc Volume and Peripapillary Deflection Volume Using Radial Optical Coherence Tomography Scans and Association with Intracranial Pressure

      Purpose: Papilledema and peripapillary deformation of Bruch’s membrane(BM) are associated with elevated intracranial pressure(ICP). We have developed a novel methodology to measure these parameters using a radial optical coherence tomography(OCT) scan pattern and apply this to test the hypothesis that ICP is associated with volumetric features of ophthalmic structures. Methods: 6-radial OCT B-scans centered over the optic nerve head were acquired in 17 subjects(30 eyes) before lumbar puncture with measurement of ICP(range:10-55 cm H2O). Internal limiting membrane(ILM) and BM were segmented. Three definitions of BM were studied to account for imaging artifact ...

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      Mentions: Stanford University

    15. Disease classification of macular Optical Coherence Tomography scans using deep learning software: validation on independent, multi-centre data

      Explore arxiv.org
      Disease classification of macular Optical Coherence Tomography scans using deep learning software: validation on independent, multi-centre data

      Purpose: To evaluate Pegasus-OCT, a clinical decision support software for the identification of features of retinal disease from macula OCT scans, across heterogenous populations involving varying patient demographics, device manufacturers, acquisition sites and operators. Methods: 5,588 normal and anomalous macular OCT volumes (162,721 B-scans), acquired at independent centres in five countries, were processed using the software. Results were evaluated against ground truth provided by the dataset owners. Results: Pegasus-OCT performed with AUROCs of at least 98% for all datasets in the detection of general macular anomalies. For scans of sufficient quality, the AUROCs for general AMD and DME ...

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      Mentions: Cardiff University Kings College London
      16. See all articles
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    1. (5 articles) Massachusetts General Hospital
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    1. (2 articles) Ruikang K. Wang
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  9. Picture Gallery

    AI-Assisted In Situ Detection of Human Glioma Infiltration Using a Novel Computational Method for Optical Coherence Tomography Motorized capsule for shadow-free OCT imaging and synchronous beam control ZEISS Marks Milestone for its New North America High Tech Site in Dublin, California Using Optical Coherence Tomography to Make Needle Biopsies Safer Identification of Retinal Biomarkers in Alzheimer’s Disease Using Optical Coherence Tomography: Recent Insights, Challenges, and Opportunities Senior Scientist on Topcon Milpitas California International Ocular Circulation Society Inaugural Meeting, August 10, 2019 Portland Oregon ZEISS Ophthalmic Digital Summit 2019 Bacterial Density and Biofilm Structure Determined by Optical Coherence Tomography Handheld spectrally encoded coherence tomography and reflectometry for motion-corrected ophthalmic optical coherence tomography and optical coherence tomography angiography Laser cleaning of paintings: in situ optimization of operative parameters through non-invasive assessment by optical coherence tomography (OCT), reflection FT-IR spectroscopy and laser induced fluorescence spectroscopy (LIF) Spatiotemporal Tracking of Brain-Tumor-Associated Myeloid Cells in Vivo through Optical Coherence Tomography with Plasmonic Labeling and Speckle Modulation

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